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Extract from the Register of European Patents

EP About this file: EP0427587

EP0427587 - Process for the preparation of AZT (3'-azido-3'-deoxy-thymidine) and related compounds [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  21.11.1997
Database last updated on 19.10.2024
Most recent event   Tooltip30.11.2007Lapse of the patent in a contracting statepublished on 02.01.2008  [2008/01]
Applicant(s)For all designated states
UNIVERSITE PIERRE ET MARIE CURIE PARIS VI
4, place Jussieu
75230 Paris Cedex 05 / FR
[N/P]
Former [1991/20]For all designated states
UNIVERSITE PIERRE ET MARIE CURIE PARIS VI
4, place Jussieu
F-75230 Paris Cedex 05 / FR
Inventor(s)01 / Czernecki, Stanislas
5 rue des Bertagnes Rubelles
F-77590 Maincy / FR
02 / Valéry, Jean-Marc
250, rue de la Faisanderie
F-77176 Nandy / FR
[1991/20]
Representative(s)Warcoin, Jacques, et al
Cabinet Regimbeau
20, rue de Chazelles
75847 Paris Cedex 17 / FR
[N/P]
Former [1991/20]Warcoin, Jacques, et al
Cabinet Régimbeau, 26, avenue Kléber
F-75116 Paris / FR
Application number, filing date90403010.325.10.1990
[1991/20]
Priority number, dateFR1989001413227.10.1989         Original published format: FR 8914132
[1991/20]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report 
No.:EP0427587
Date:15.05.1991
Language:FR
[1991/20]
Type: B1 Patent specification 
No.:EP0427587
Date:15.01.1997
Language:FR
[1997/03]
Search report(s)(Supplementary) European search report - dispatched on:EP25.03.1991
ClassificationIPC:C07H19/073
[1991/20]
CPC:
C07H19/06 (EP,US); C07H19/073 (KR); A61P31/12 (EP);
A61P31/18 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [1991/20]
TitleGerman:Verfahren zur Herstellung von AZT(3'-azido-3'-desoxythymidin) und diebezüglichen Verbindungen[1991/20]
English:Process for the preparation of AZT (3'-azido-3'-deoxy-thymidine) and related compounds[1991/20]
French:Procédé de préparation de l'AZT (azido-3'-désoxy-3'-thymidine) et de composés apparentés[1991/20]
Examination procedure08.07.1991Examination requested  [1991/36]
09.02.1993Despatch of a communication from the examining division (Time limit: M06)
26.07.1993Reply to a communication from the examining division
25.04.1994Despatch of a communication from the examining division (Time limit: M06)
12.09.1994Reply to a communication from the examining division
02.11.1995Despatch of a communication from the examining division (Time limit: M04)
27.12.1995Reply to a communication from the examining division
20.02.1996Despatch of communication of intention to grant (Approval: Yes)
01.07.1996Communication of intention to grant the patent
30.09.1996Fee for grant paid
30.09.1996Fee for publishing/printing paid
Opposition(s)16.10.1997No opposition filed within time limit [1998/02]
Fees paidRenewal fee
21.09.1992Renewal fee patent year 03
27.09.1993Renewal fee patent year 04
19.12.1994Renewal fee patent year 05
18.09.1995Renewal fee patent year 06
24.09.1996Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
31.10.199405   M06   Fee paid on   19.12.1994
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT15.01.1997
DK15.01.1997
ES15.01.1997
FR15.01.1997
GB15.01.1997
GR15.01.1997
IT15.01.1997
NL15.01.1997
SE15.04.1997
DE16.04.1997
[2008/01]
Former [2003/07]AT15.01.1997
DK15.01.1997
ES15.01.1997
FR15.01.1997
GB15.01.1997
GR15.01.1997
IT15.01.1997
NL15.01.1997
SE15.04.1997
DE16.04.1997
Former [2002/32]AT15.01.1997
DK15.01.1997
ES15.01.1997
FR15.01.1997
GB15.01.1997
GR15.01.1997
IT15.01.1997
SE15.04.1997
DE16.04.1997
Former [2002/25]AT15.01.1997
DK15.01.1997
ES15.01.1997
GB15.01.1997
GR15.01.1997
IT15.01.1997
SE15.04.1997
DE16.04.1997
Former [2000/04]AT15.01.1997
DK15.01.1997
GB15.01.1997
GR15.01.1997
IT15.01.1997
SE15.04.1997
DE16.04.1997
Former [1999/42]AT15.01.1997
DK15.01.1997
GB15.01.1997
IT15.01.1997
SE15.04.1997
DE16.04.1997
Former [1998/15]AT15.01.1997
DK15.01.1997
GB15.01.1997
SE15.04.1997
DE16.04.1997
Former [1998/11]AT15.01.1997
GB15.01.1997
SE15.04.1997
DE16.04.1997
Former [1997/43]AT15.01.1997
GB15.01.1997
DE16.04.1997
Former [1997/42]AT15.01.1997
GB15.01.1997
Documents cited:Search[Y]JP77122398  ;
 [X]EP0199451  (WELLCOME FOUND [GB]);
 [X]US4681933  (CHU CHUNG K [US], et al);
 [X]WO8805657  (CHU CHUNG K [US], et al);
 [X]EP0325537  (UNIV PARIS CURIE [FR])
 [X]  - JOURNAL OF MEDICINAL CHEMISTRY, vol. 26, 1983, pages 544-548, American Chemical Society; T.-S. LIN et al.: "Synthesis and antineoplastic activity of 3'-azido and 3'-amino analogues of pyrimidine deoxyribonucleoside"
 [X]  - EUR. J. MED. CHEM. - CHIM. THER., vol. 20, no. 4, 1985, pages 295-301; L. COLLA et al.: "Synthesis and biological activity of 3'-azido- and 3'-amino substituted nucleoside analogs"
 [X]  - JOURNAL OF ORGANIC CHEMISTRY, vol. 38, no. 25, 1973, pages 4299-4305; R.P. GLINSKI et al.: "Nucleotide synthesis. IV. Phosphorylated 3'-amino-3'-deoxythymidine and 5'-amino-5'-deoxythymidine and derivatives"
 [Y]  - CHEMICAL ABSTRACTS, vol. 88, 1978, pages 590-591, résumé no. 12166x, Columbus, Ohio, US; & JP-A-77 122 398 (YAMASA SHOYU CO., LTD) 14-10-1977, & JP77122398 A 00000000
 [Y]  - BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, vol. 52, no. 4, avril 1979, pages 1191-1196; J. KIMURA et al.: "Studies on nucleosides and nucleotides. VII. Preparation of pyrimidine nucleoside 5'-phosphates and N3,5'-purine cyclonucleosides by selective activation of the 5'-hydroxyl group"
 [X]  - JUSTUS LIEBIGS ANNALEN DER CHEMIE, 1978, pages 78-86, Verlag Chemie, GmbH, Weinheim, DE; H. LOIBNER et al.: "Reaktionen mit phosphororganischen Verbindungen, XLIII. Strukturelle Abwandlungen an Nucleosiden mit Hilfe von Triphenylphosphan/Azodicarbonsäureester"
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.