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Extract from the Register of European Patents

EP About this file: EP0465508

EP0465508 - PHARMACEUTICAL COMPOSITION FOR INSULIN-RESISTANT DIABETICS [Right-click to bookmark this link]
Former [1992/03]DIETARY SUPPLEMENT FOR INSULIN-RESISTANT DIABETICS
[2000/22]
StatusNo opposition filed within time limit
Status updated on  30.03.2001
Database last updated on 06.07.2024
Most recent event   Tooltip30.03.2001No opposition filed within time limitpublished on 16.05.2001 [2001/20]
Applicant(s)For all designated states
THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Towers Office Building, Suite 6-211, 1224 West Main Street Charlottesville
Virginia 22903 / US
[N/P]
Former [1997/44]For all designated states
THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Towers Office Building, Suite 6-211, 1224 West Main Street
Charlottesville, Virginia 22903 / US
Former [1992/03]For all designated states
THE UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION
Towers Office Building, Suite 6-211, 1224 West Main Street
Charlottesville, Virginia 22903 / US
Inventor(s)01 / LARNER, Joseph
1432 Grove Road
Charlottesville, VA 22901 / US
02 / KENNINGTON, Allison
9331 Palmer Place
Laurel, Maryland 20708 / US
[1992/03]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [1995/13]VOSSIUS & PARTNER
Postfach 86 07 67
D-81634 München / DE
Former [1992/03]Orès, Bernard
Cabinet ORES 6, Avenue de Messine
F-75008 Paris / FR
Application number, filing date90905048.608.03.1990
[1992/03]
WO1990US01109
Priority number, dateUS1989032048208.03.1989         Original published format: US 320482
[1992/03]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9010439
Date:20.09.1990
Language:EN
[1990/22]
Type: A1 Application with search report 
No.:EP0465508
Date:15.01.1992
Language:EN
The application published by WIPO in one of the EPO official languages on 20.09.1990 takes the place of the publication of the European patent application.
[1992/03]
Type: B1 Patent specification 
No.:EP0465508
Date:31.05.2000
Language:EN
[2000/22]
Search report(s)International search report - published on:US20.09.1990
(Supplementary) European search report - dispatched on:EP25.03.1992
ClassificationIPC:A61K31/045
[1992/03]
CPC:
A61K31/047 (EP,US); A23L29/37 (EP,US); A61P3/00 (EP);
A61P3/08 (EP); A61P3/10 (EP); A61P43/00 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   IT,   LI,   LU,   NL,   SE [1992/03]
TitleGerman:ARZNEIMITTEL FÜR INSULINRESISTENTE DIABETIKER[2000/22]
English:PHARMACEUTICAL COMPOSITION FOR INSULIN-RESISTANT DIABETICS[2000/22]
French:PREPARATION PHARMACEUTIQUE POUR DIABETIQUES RESISTANT A L'INSULINE[2000/22]
Former [1992/03]DIÄTSUPPLEMENT FÜR INSULINRESISTENTE DIABETIKER
Former [1992/03]DIETARY SUPPLEMENT FOR INSULIN-RESISTANT DIABETICS
Former [1992/03]COMPLEMENT DIETETIQUE POUR DIABETIQUES RESISTANT A L'INSULINE
Entry into regional phase12.08.1991National basic fee paid 
12.08.1991Search fee paid 
12.08.1991Designation fee(s) paid 
12.08.1991Examination fee paid 
Examination procedure27.09.1990Request for preliminary examination filed
International Preliminary Examining Authority: DE
14.08.1991Examination requested  [1992/03]
01.12.1994Despatch of a communication from the examining division (Time limit: M04)
11.04.1995Reply to a communication from the examining division
26.04.1996Despatch of a communication from the examining division (Time limit: M06)
05.11.1996Reply to a communication from the examining division
24.08.1998Despatch of communication of intention to grant (Approval: No)
15.03.1999Despatch of a communication from the examining division (Time limit: M04)
26.07.1999Reply to a communication from the examining division
29.07.1999Despatch of communication of intention to grant (Approval: later approval)
17.08.1999Communication of intention to grant the patent
19.11.1999Fee for grant paid
19.11.1999Fee for publishing/printing paid
Opposition(s)01.03.2001No opposition filed within time limit [2001/20]
Fees paidRenewal fee
13.03.1992Renewal fee patent year 03
09.03.1993Renewal fee patent year 04
09.03.1994Renewal fee patent year 05
13.03.1995Renewal fee patent year 06
07.03.1996Renewal fee patent year 07
27.03.1997Renewal fee patent year 08
30.03.1998Renewal fee patent year 09
04.03.1999Renewal fee patent year 10
06.03.2000Renewal fee patent year 11
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Documents cited:Search[X]EP0179439  (SIREN MATTI);
 [E]EP0359257  (SIREN MATTI)
 [X]  - METABOLISM, CLINICAL AND EXPERIMENTAL, vol. 35, no. 4, suppl. 1, April 1986, pages 41-45; J.R. WILLIAMSON et al.: "Diabetes-induced increases in vascular permeability and changes in granulation tissue levels of sorbitol, myo-inositol, chiro-inositol, and scyllo-inositol are prevented by sorbinil"
 [Y]  - MONATSHEFTO FÜR CHEMIE, vol. 102, 1971, pages 459-464; G. WÖBER et al.: "Untersuchungen über die Biosynthese der Cyclite, 27. Mitt: Ein Dehydrogenase-System, das die Epimerisierung von myo-Inosit zu D-chiro-Inosit in Chlorella fusca katalysieren kann"
International search[Y]  - CHEMICAL ABSTRACT, Volume 83, No. 5 issued 4 August 1975 (Columbus, Ohio, USA) GREENE, DOUGLAS A.; DEJESUS, PACIFICO V. Jr.; WINEGRADE, ALBERT I. "Effects of insulin and dietary myoinositol on impaired peripheral motor nerve conduction velocity in acute streptozotocin diabetes", page Number 85, Abstract Number 38125w. J. Clin. Invest. 1975 55(6), 1326-36 (Eng.).
 [Y]  - CHEMICAL ABSTRACT, Volume 86, No. 21 issued 23 May 1977 (Columbus, Ohio, USA) CLEMENTS, REX S. Jr.; REYNERTSON, RICHARD; "Myoinositol metabolism in diabetes mellitus. Effect of insulin treatment". Page No. 75, Abstract No 150902k, Diabetes 1977, 26(3), 215-21 (Eng).
 [Y]  - CHEMICAL ABSTRACT, Column 109, No. 9 issued 29 August 1988 (Columbus, Ohio, USA); PRICE, DAVID E.; AIREY, C. MARK; ALANI, SHAKIR M.; WALES, JOHN K. "Effect of aldose reductase inhibition nerve conduction velocity and resistance to ischemic conduction block in experimental diabetes. Page No. 317, Abstract No. 71448g; Diabetes 1988, 37(7), 969-73 (Eng).
 [Y]  - CHEMICAL ABSTRACT, Volume 111, No. 7 issued 14 August 1989 (Columbus, Ohio, USA); KNUDSEN, G.M.; JAKOBSEN, J,; BARRY, D.I.; COMPTON, A.M.; TOMLIMSON, D. R.; Myo-inositol normalizes decreased sodium permeability of the blood-brain barrier in streptozotocin diabetes. Page No. 64, Abstract No. 50387n; Neuroscience (Oxford) 1989, 29(3), 773-7 (Eng).
 [Y]  - MIKKO HALLMAN, PIRKKO ARJOMAA KALLE HOPPU; "Inositol supplementation in respiratory distress syndrome: Relationship between serum concentration, renal excretion and lung effluent phospholipids", Pediatrics 1987, 110, page 604-610. See page 605, column 1 last paragraph.
 [Y]  - REX S. CLEMENTS, "New Therapies for Chronic Complications of Older Diabete Patients"; American Journal of Medicine 1986, 80(Supp ISA) pages 54-60.
 [Y]  - D.A. GREENE, S.A. LATTIMER; "Impaired Rat Sciatic Nerve Sodium-Potassium adenosine Triphosphatase in acute streptozocin Diabetes and its correction by Dietary Myo-Inositol Supplementation" Jourmal Clinical Investigation, 1983, Volume 72, pages 1058-1063. See pages 1060, column 1.
 [Y]  - BRUCE J. HOLUB "The Nutritional Significance, Metabolism and Function of Myo-inositol and phosphatidylinosital in Health and Disease". Advanced Nutrition Research, 1982 Volume 4, page 107-141, see pages 127-128.
 [A]  - M. WINDHOLZ "The Merck Index"; 1983, page 722, Number 4861, see "recemic form occur naturely".
 [A]  - ICN Cataloge, 1989 Page AD-19, Hamster diet Inositol as part of Vitamin mix.
 [A]  - Biological Abstracts Volume 75, Number 1 issued January 1, 1983 (Philadelphia, PA, USA) PHILLIPS, D.V., DOUGHERTY, D.E.; SMITH, A.E. "Cyclitols in soybean". Abstract Number 5921; J. Agric Food. Chem. 1982, 30(3) 456-458.
 [A]  - Biological Abstract Volume 83, Number 3 issued February 1, 1987 (Philadelphia, PA USA) BAUMGARTNER, S.; GENNAR-RTIZMANN, R.; HAAS, J.; AMADO. R.; NWUKAM H. "Isolation and identification of Cyclitols in carob pods" Abstract Number 23318; J. Agric. Food Chem. 1986 34(5), 827-829.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.