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EP About this file: EP0520987

EP0520987 - METHOD OF SUPPRESSING APPETITE BY ADMINISTRATION OF TETRAHYDRO-$g(b)-CARBOLINE DERIVATIVES [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 08.01.1996 Database last updated on 15.06.2024
Most recent event Tooltip	08.01.1996	Application deemed to be withdrawn	published on 07.02.1996 [1996/06]
Applicant(s)	For all designated states NEUREX CORPORATION 3760 Haven Avenue Menlo Park, CA 94025-1057 / US
	[1993/01]
Inventor(s)	01 / BARCHAS, Jack, D. 669 Mirada Avenue Stanford, CA 94305 / US
	02 / ELLIOT, Glen, R. 1513 Bedford Avenue Sunnyvale, CA 94087 / US
	03 / ADRIAENSSENS, Peter, I. 365 Monroe Drive Palo Alto, CA 94306 / US
	04 / BITNER, Robert, S. 173 Sierra Vista 3 Mountain View, CA 94041 / US
	05 / BOWERSOX, Stephen, S. 148 Dunsmuir Way Menlo Park, CA 94025 / US
	06 / NADASDI, Laszlo 1431 15th Avenue San Francisco, CA 94122 / US
	[1993/01]
Representative(s)	West, Alan Harry, et al R.G.C. Jenkins & Co 26 Caxton Street London SW1H 0RJ / GB
	[N/P]
Former [1993/01]	West, Alan Harry, et al R.G.C. Jenkins & Co. 26 Caxton Street London SW1H 0RJ / GB
Application number, filing date	90909319.7	07.06.1990
	[1993/01]
	WO1990US03249
Priority number, date	US19890363504	08.06.1989 Original published format: US 363504
	[1993/01]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9014827
	Date:	13.12.1990
	Language:	EN
	[1990/28]
	Type:	A1 Application with search report
	No.:	EP0520987
	Date:	07.01.1993
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 13.12.1990 takes the place of the publication of the European patent application.
	[1993/01]
Search report(s)	International search report - published on:	US	13.12.1990
	(Supplementary) European search report - dispatched on:	EP	13.05.1992
Classification	IPC:	A61K31/44	[1993/01]
	CPC:	A61K31/44 (EP,US); A61P3/04 (EP)
Designated contracting states	AT, BE, CH, DE, DK, ES, FR, GB, IT, LI, LU, NL, SE [1993/01]
Title	German:	METHODE ZUR APPETITZÜGELUNG DURCH VERABREICHUNG VON TETRAHYDRO-G(B)-CARBOLINDERIVATEN	[1993/01]
	English:	METHOD OF SUPPRESSING APPETITE BY ADMINISTRATION OF TETRAHYDRO-$g(b)-CARBOLINE DERIVATIVES	[1993/01]
	French:	PROCEDE DE SUPPRESSION DE L'APPETIT PAR ADMINISTRATION DE DERIVES DE TETRAHYDRO-$g(b)-CARBOLINE	[1993/01]
File destroyed:	03.03.2001
Entry into regional phase	03.01.1992	National basic fee paid
	03.01.1992	Search fee paid
	03.01.1992	Designation fee(s) paid
	03.01.1992	Examination fee paid
Examination procedure	13.12.1990	Request for preliminary examination filed International Preliminary Examining Authority: DE
	03.01.1992	Examination requested [1993/01]
	16.03.1994	Despatch of a communication from the examining division (Time limit: M06)
	24.11.1994	Reply to a communication from the examining division
	24.03.1995	Despatch of a communication from the examining division (Time limit: M04)
	04.08.1995	Application deemed to be withdrawn, date of legal effect [1996/06]
	08.09.1995	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [1996/06]
Request for further processing for:	24.11.1994	Request for further processing filed
	24.11.1994	Full payment received (date of receipt of payment) Request granted
	10.03.1995	Decision despatched
Fees paid	Renewal fee
	09.06.1992	Renewal fee patent year 03
	14.06.1993	Renewal fee patent year 04
	11.06.1994	Renewal fee patent year 05
	12.06.1995	Renewal fee patent year 06
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[Y]US3202671 (JACOB SZMUSZKOVICZ);
		[A]EP0302788 (SYNTHELABO [FR]);
		[AP]WO8912447 (NEUREX CORP [US]);
		[XP]WO9003168 (NEUREX CORP [US])
		[XD] - MEDICAL BIOLOGY, vol. 59, no. 4, 1981, pages 190-211; M.M. AIRAKSINEN et al.: "Beta-carbolines, psychoactive compounds in the mammalian body"
		[Y] - PHARMACOLOGY BIOCHEMISTRY & BEHAVIOR, vol. 1, no. 3, 1973, pages 255-258; D.M. NANCE et al.: "Effects of dl-para-chlorophenylalanine on sucrose preference and intake: reversal by 5-hydroxytryptophan and 6-methoxy 1,2,3,4-tetrahydro-beta-carboline"
		[X] - JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 58, no. 8, 1969, pages 998-1001; B.T. HO et al.: "Inhibitors of monoamine oxidase IV: 6(or 8)-substituted tetrahydro-beta-carbolines and their 9-methyl analogs"
		[X] - JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 57, no. 8, 1989, pages 1364-1369; B.T. HO et al.: "Inhibitors of monoamine oxidase II. Synthesis of some N-2(9)-substituted tetrahydro-beta-carbolines and evaluation of their inhibitory activities"
		[Y] - PHARMACOLOGY BIOCHEMISTRY & BEHAVIOR, vol. 24, no. 5, 1986, pages 1209-1213; M.D. SCHECHTER: "Serotonergic mediation of tetrahydro-beta-carboline"
		[Y] - PHARMACY AND PHARMACOLOGY, vol. 28, no. 4, 1976, pages 318-320; A.J. GOUDIE et al.: "Effects of lilly 110140, a specific inhibitor of 5-hydroxytryptamine uptake, on food intake and on 5-hydroxytryptophan-induced anorexia. Evidence for serotoninergic inhibition of feeding"
		[X] - ARCHIV DER PHARMAZIE, vol. 314, no. 7, 1981, pages 627-630; K. REHSE et al.: "Thrombocytenaggregationshemmung durch 1,2,3,4-Tetrahydro-beta-carboline: Ein Hinweis auf serotoninantagonistische Eigenschaften dieser Substanzklasse"
		[AD] - JOURNAL OF MEDICINAL CHEMISTRY, vol. 25, no. 9, 1982, pages 1081-1091; M. CAIN et al.: "Beta-carbolines: synthesis and neurochemical and phramacological actions on brain benzodiazepine receptors"
	International search	[A]EP0304223 (MERCK & CO INC [US])
		[X] - COOPER, et al. Pharmacol. Biochem. Behav. 1986 25 (1) 99-106 CHEMICAL ABSTRACTS Vol. 105, 1986 Abstract: 127278p.
		[A] - GLASSMAN, et al Science 226. 1984 p. 883-6 (Entire document).
		[A] - DEWAR, et al JACS 84. 1962 pp 3548 to 3553 (Entire document).
		[A] - ROBERTSON, et al European J. Pharmacol 76 (1981) 281-284 (Entire document).
		[X] - ROMMELSPACHER, et al Naunyn-Schiedeberg's Arch Pharmacol. 298 83-91 (1977) p. 84 to 86.

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