Deutsch English Français

Contact

EP0432249

European procedure

Quick help

Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...

News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...

Extract from the Register of European Patents

EP About this file: EP0432249

EP0432249 - MONOCLONAL ANTIBODIES AGAINST LEUKOCYTE ADHESION RECEPTOR BETA-CHAIN, METHODS OF PRODUCING THESE ANTIBODIES AND USE THEREFORE [Right-click to bookmark this link]
Former [1991/25]	MONOCLONAL ANTIBODIES AGAINST LEUKOCYTE ADHESION RECEPTOR $g(b)-CHAIN, METHODS OF PRODUCING THESE ANTIBODIES AND USE THEREFORE
	[1996/39]
Status	No opposition filed within time limit Status updated on 01.08.1997 Database last updated on 20.07.2024
Most recent event Tooltip	01.08.1997	No opposition filed within time limit	published on 17.09.1997 [1997/38]
Applicant(s)	For all designated states THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE 720 Rutland Avenue Baltimore, MD 21205 / US
	[1995/05]
Former [1991/25]	For all designated states THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (a Maryland corporation) 720 Rutland Avenue Baltimore, Maryland / US
Inventor(s)	01 / HILDRETH, James, E. 407 North Chapel Street Baltimore, MD 21231 / US
	[1991/25]
Representative(s)	Vossius & Partner Patentanwälte Rechtsanwälte mbB Siebertstrasse 3 81675 München / DE
	[N/P]
Former [1991/25]	VOSSIUS & PARTNER Postfach 86 07 67 D-81634 München / DE
Application number, filing date	90909864.2	30.05.1990
	[1991/25]
	WO1990US02979
Priority number, date	US19890361271	02.06.1989 Original published format: US 361271
	[1991/25]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO9015076
	Date:	13.12.1990
	[1990/28]
	Type:	A1 Application with search report
	No.:	EP0432249
	Date:	19.06.1991
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 13.12.1990 takes the place of the publication of the European patent application.
	[1991/25]
	Type:	B1 Patent specification
	No.:	EP0432249
	Date:	25.09.1996
	Language:	EN
	[1996/39]
Search report(s)	International search report - published on:	US	18.04.1991
	(Supplementary) European search report - dispatched on:	EP	14.11.1991
Classification	IPC:	C07K16/28, C12N5/12, A61K51/00, A61K39/395, G01N33/53, G01N33/535	[1992/01]
	CPC:	C07K16/2845 (EP,US); A61P37/00 (EP); A61P37/02 (EP); A61K38/00 (EP,US)
	Former IPC [1991/25]	C07K15/28, C12N5/12, A61K43/00, A61K39/395, G01N33/53, G01N33/535
Designated contracting states	AT, BE, CH, DE, DK, ES, FR, GB, IT, LI, LU, NL, SE [1991/25]
Title	German:	GEGEN DIE BETA-KETTE DES LEUKOZYTEN-ADHÄSIONS-REZEPTORS GERICHTETE MONOKLONALE ANTIKÖRPER, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG	[1996/39]
	English:	MONOCLONAL ANTIBODIES AGAINST LEUKOCYTE ADHESION RECEPTOR BETA-CHAIN, METHODS OF PRODUCING THESE ANTIBODIES AND USE THEREFORE	[1996/39]
	French:	ANTICORPS MONOCLONAUX CONTRE LA CHAINE BETA DE RECEPTEURS D'ADHESION DE LEUCOCYTES, PROCEDE DE PRODUCTION DE CES ANTICORPS ET UTILISATION	[1996/39]
	Former [1991/25]	GEGEN DIE BETA-KETTE DES LEUKOZYT-ADHÄSIONS-REZEPTORS GERICHTETE MONOKLONALE ANTIKÖRPER, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG
	Former [1991/25]	MONOCLONAL ANTIBODIES AGAINST LEUKOCYTE ADHESION RECEPTOR $g(b)-CHAIN, METHODS OF PRODUCING THESE ANTIBODIES AND USE THEREFORE
	Former [1991/25]	ANTICORPS MONOCLONAUX CONTRE LA CHAINE $g(b) DE RECEPTEURS D'ADHESION DE LEUCOCYTES, PROCEDE DE PRODUCTION DE CES ANTICORPS ET UTILISATION
Biological material	This application mentions deposited biological material, check the file for details
Entry into regional phase	27.02.1991	National basic fee paid
	27.02.1991	Search fee paid
	27.02.1991	Designation fee(s) paid
	12.05.1992	Examination fee paid
Examination procedure	12.05.1992	Examination requested [1992/29]
	08.11.1993	Despatch of a communication from the examining division (Time limit: M04)
	18.03.1994	Reply to a communication from the examining division
	10.08.1994	Despatch of a communication from the examining division (Time limit: M04)
	20.12.1994	Reply to a communication from the examining division
	10.02.1995	Despatch of a communication from the examining division (Time limit: M06)
	21.08.1995	Reply to a communication from the examining division
	26.09.1995	Despatch of communication of intention to grant (Approval: No)
	07.02.1996	Despatch of communication of intention to grant (Approval: later approval)
	15.03.1996	Communication of intention to grant the patent
	18.06.1996	Fee for grant paid
	18.06.1996	Fee for publishing/printing paid
Opposition(s)	26.06.1997	No opposition filed within time limit [1997/38]
Fees paid	Renewal fee
	27.05.1992	Renewal fee patent year 03
	14.04.1993	Renewal fee patent year 04
	02.05.1994	Renewal fee patent year 05
	11.05.1995	Renewal fee patent year 06
	22.04.1996	Renewal fee patent year 07
	Penalty fee
	Penalty fee Rule 85b EPC 1973
	12.05.1992	M01 Fee paid on 12.05.1992
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	EP0314863 [ ] (BAYLOR COLLEGE MEDICINE [US], et al);
		EP0346078 [ ] (UNIV ROCKEFELLER [US]);
		EP0365837 [ ] (DANA FARBER CANCER INST INC [US])
		[ ] - Journal of Immunology, Vol. 136, No. 12, 15 June 1986, Baltimore, USA, pages 4548-4553; T. POHLMAN et al.: "An endothelial cell surface factors induced in vitro by polysaccharide, interleukin 1, and tumor necrosis factor-alpha increases neutrophil adherence by a CDw18-dependent mechanism", the whole document.
		[ ] - R. LARSON et al. IN: "Leucocyte Typing IV. White cell differentiation antigens. Eds. W. KNAPP et al.", 1989, Oxford University Press, Oxford, GB, see pages 566-570.
		[ ] - M. DIAMOND et al. IN: "Leucocyte Typing IV. White cell differentiation antigens. Eds. W. KNAPP et al.", 1989, Oxford University Press, Oxford, GB, see pages 570-574.
	International search	[Y]US4506009 (LENHOFF HOWARD M [US], et al);
		[Y]WO8806592 (DANA FARBER CANCER INST INC [US])
		[X] - EUROPEAN JOURNAL OF IMMUNOLOGY, Vol. 17, issued 1987, KEIZER et al., "The Role of p150, 95 in Adhesion, Migration, Chemotaxis and Phagocytosis of Human Monocytes", pp. 1317-1322.
		[X] - IMMUNOLOGY, Vol. 61, issued 1987, "Differential Function of LFA-1 Family Molecules, CCD11 and CD18 in Adhesion of Human Monocytes", pp. 261-267.
		[Y] - THE JOURNAL OF IMMUNOLOGY, Vol. 134, No. 5, issued May 1985, HILDRETH et al., "The Human Lymphocyte Function-Associated (HLFA) Antigen and a Related Macrophage Differentiation Antigen (HMAC-1): Functional Effects of Subunit-Specific Monoclonal Antibodies", pp. 3272-3280.
		[Y] - WEIR D.M., "Handbook of Experimental Immunology", Vol. 4, Published 1986, by BLACKWELL SCIENTIFIC PUBLICATIONS (OXFORD), pages 108.1-108.9.
		[Y] - McMICHAEL A.J., "Leukocyte Typing III White Cell Differentiation Antigens", Published 1987, by OXFORD UNIVERSITY PRESS (OXFORD), pages 839-844.
		[X] - THE JOURNAL OF BIOLOGICAL CHEMISTRY, Vol. 262, No. 12, issued 25 April 1987, HICKSTEIN et al., "Isolation and Characterization of the Receptor on Human Neutrophils that Mediates Cellular Adherence", pp. 5576-5580.
		[X] - JOURNAL OF EXPERIMENTAL MEDICINE, Vol. 158, issued December 1983, SANCHEZ-MADRID et al., "A Human Leukocyte Differentiation Antigen Family with Distinct alpha-Subunits and a Common beta-Subunit: The Lymphocyte Function-Associated Antigen (LFA-1), the C3B-1 Complement Receptor 01CM1/ MAC-1) and p150, 95 Molecule", pp. 1785-1803.
		[X] - SCANDANAVIAN JOURNAL OF IMMUNOLOGY, Vol. 28, issued November 1988, NORTAMO et al., "Immunological Mapping of the Human Leukocyte Adhesion Glycoprotein GP90 (CD18) by Monoclonal Antibodies", pp. 537-546.
	Examination	- European Journal of Immunology, vol. 17, issued 1987, "The Role of p150, 95 in Adhesion, Migration, Chemotaxis and Phagocytosis of Human Monocytes", (Keizer et al.), pp. 1317-1322, see pp. 1317-1318.
		- IMMUNOLOGY, vol. 61, issued 1987, "DIFFERENTIAL FUNCTION OF LFA-1 Family Molecules, CCD11 and CD18 in Adhesion of human Monocytes, pp. 261-267, see pp. 261-262
		- The Journal of Biological Chemistry, vol. 262, no. 12 issued 25 April 1987. "Isolation and Characterization of the receptor on human Neutrophils that mediates cellular adherence", (Hickstein et al.), pp. 5576-5580, see p. 5576
		- Journal of Experimental Medicine, vol. 158, issued December 1983, "A human Leukocyte differentiation antigen family with distinct alpha-sub- units and a common beta-subunit: The lymphocyte function-associated antigen (LFA-1), the C3B-1 complement receptor O1CM1/MAC-1) and p150, 95 Molecule", (Sanchez-Madrid et al.), pp. 1785-1803, see pp. 1875-1877.
		- Scandanavian Journal of Immunology, vo. 28, issued November 1988, "Immunological mapping of the human leukocyte adhesion Glycoprotein (GP90 (Cd18) by monoclonal antibodies", (Nortamo et al.), pp. 537-546, see pp. 537-539

The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.

Legal notice
Terms of use
24.2.25; 35p