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Extract from the Register of European Patents

EP About this file: EP0511306

EP0511306 - TUMOR KILLING EFFECTS OF ENTEROTOXINS AND RELATED COMPOUNDS [Right-click to bookmark this link]
StatusPatent revoked
Status updated on  22.04.2005
Database last updated on 02.07.2024
Most recent event   Tooltip15.08.2008Change - representativepublished on 17.09.2008  [2008/38]
Applicant(s)For all designated states
Terman, David S.
3183 Palmero Way
Pebble Beach, CA 93953 / US
For all designated states
STONE, Jay L.
7325 Viewpoint Rd.
Aptos, CA 95003 / US
[N/P]
Former [2002/29]For all designated states
TERMAN, David S.
3183 Palermo Way
Pebble Beach, CA 93953 / US
For all designated states
STONE, Jay L.
7325 Viewpoint Rd.
Aptos, CA 95003 / US
Former [2001/30]For all designated states
TERMAN, David S.
3183 Palermo Way
Pepple Beach, CA 93953 / US
For all designated states
STONE, Jay L.
7325 Wiewpoint Rd.
Aptos, CA 95003 / US
Former [1992/45]For all designated states
TERMAN, David S.
3183 Palermo Way
Pepple Beach, CA 93953 / US
For all designated states
STONE, Jay L.
2695 Estate Drive
Aptos, CA 95003 / US
Inventor(s)01 / see applicant
...
[1992/45]
Representative(s)Wichmann, Hendrik, et al
Patentanwälte
Isenbruck Bösl Hörschler PartG mbB
Prinzregentenstrasse 68
81675 München / DE
[N/P]
Former [2008/38]Wichmann, Hendrik, et al
Isenbruck Bösl Hörschler Wichmann Huhn Patentanwälte Prinzregentenstrasse 68
81675 München / DE
Former [2003/28]Wichmann, Hendrik, Dr., et al
Patentanwälte Isenbruck Bösl Hörschler Wichmann Huhn Postfach 86 08 80
81635 München / DE
Former [2002/29]Wichmann, Hendrik, Dr., et al
Patent- und Rechtsanwälte Bardehle - Pagenberg - Dost Altenburg - Geissler - Isenbruck, Galileiplatz 1
81679 München / DE
Former [2001/03]Wichmann, Hendrik
Patent- und Rechtsanwälte Bardehle - Pagenberg - Dost Altenburg - Geissler - Isenbruck, Galileiplatz 1
81679 München / DE
Former [2000/09]Glawe, Delfs, Moll & Partner
Patentanwälte Liebherrstrasse 20
80538 München / DE
Former [1999/50]Keussen, Christof, Dr., et al
Glawe, Delfs, Moll & Partner Patentanwälte Rothenbaumchaussee 58
20148 Hamburg / DE
Former [1996/20]O'Brien, Caroline Jane, et al
MEWBURN ELLIS York House 23 Kingsway
London WC2B 6HP / GB
Former [1992/45]Daniels, Jeffrey Nicholas, et al
Page White & Farrer 54 Doughty Street
London WC1N 2LS / GB
Application number, filing date91903963.617.01.1991
[1992/45]
WO1991US00342
Priority number, dateUS1990046657717.01.1990         Original published format: US 466577
[1992/45]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9110680
Date:25.07.1991
Language:EN
[1991/17]
Type: A1 Application with search report 
No.:EP0511306
Date:04.11.1992
Language:EN
The application published by WIPO in one of the EPO official languages on 25.07.1991 takes the place of the publication of the European patent application.
[1992/45]
Type: B1 Patent specification 
No.:EP0511306
Date:17.07.2002
Language:EN
[2002/29]
Search report(s)International search report - published on:US25.07.1991
(Supplementary) European search report - dispatched on:EP08.03.1993
ClassificationIPC:C07K14/31, A61K38/16
[2001/10]
CPC:
C07K14/315 (EP); A61K31/192 (EP); A61K39/4611 (EP);
A61K39/4622 (EP); A61K39/4632 (EP); A61K39/464821 (EP);
A61K39/464822 (EP); A61K45/06 (EP); A61P35/00 (EP);
C07K14/31 (EP); A61K38/00 (EP); C12N2510/00 (EP) (-)
C-Set:
A61K31/192, A61K2300/00 (EP);
A61K39/464821, A61K2300/00 (EP);
A61K39/464822, A61K2300/00 (EP)
Former IPC [1992/45]C07K7/10, C07K13/00
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [1992/45]
TitleGerman:TUMOR-ZERSTÖRENDE EFFEKTE VON ENTEROTOXINEN UND VERWANDTEN VERBINDUNGEN[1992/45]
English:TUMOR KILLING EFFECTS OF ENTEROTOXINS AND RELATED COMPOUNDS[1992/45]
French:EFFETS DES ENTEROTOXINES ET DE COMPOSES APPARENTES POUR L'ELIMINATION DE TUMEURS[1992/45]
Entry into regional phase14.08.1992National basic fee paid 
14.08.1992Search fee paid 
14.08.1992Designation fee(s) paid 
14.08.1992Examination fee paid 
Examination proceduredeletedDecision about request for accelerated examination - accepted: No
13.08.1991Request for preliminary examination filed
International Preliminary Examining Authority: DE
14.08.1992Examination requested  [1992/45]
06.12.1995Despatch of a communication from the examining division (Time limit: M06)
26.09.1996Reply to a communication from the examining division
22.04.1997Despatch of a communication from the examining division (Time limit: M04)
25.06.1997Reply to a communication from the examining division
19.11.1997Despatch of a communication from the examining division (Time limit: M06)
29.06.1998Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
27.08.1998Reply to a communication from the examining division
24.03.1999Despatch of a communication from the examining division (Time limit: M04)
14.06.1999Reply to a communication from the examining division
25.08.1999Despatch of a communication from the examining division (Time limit: M06)
04.02.2000Reply to a communication from the examining division
10.02.2000Request for accelerated examination filed
06.10.2000Date of oral proceedings
02.11.2000Despatch of a communication from the examining division (Time limit: M02)
02.11.2000Minutes of oral proceedings despatched
09.01.2001Reply to a communication from the examining division
27.02.2001Despatch of communication of intention to grant (Approval: No)
18.10.2001Despatch of communication that the application is refused, reason: formalities examination {1}
28.12.2001Despatch of communication of intention to grant (Approval: later approval)
15.03.2002Communication of intention to grant the patent
02.05.2002Fee for grant paid
02.05.2002Fee for publishing/printing paid
Divisional application(s)EP01102715.8  / EP1103268
EP01104586.1  / EP1129717
Opposition(s)Opponent(s)01  16.04.2003  19.05.2003  ADMISSIBLE
ACTIVE BIOTECH AB
PO Box 724, Scheelevagen 22
SE-220 07 Lund / SE
Opponent's representative
Roques, Sarah Elizabeth
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
 [N/P]
Former [2003/25]
Opponent(s)01  16.04.2003   
ACTIVE BIOTECH AB
PO Box 724, Scheelevagen 22
SE-220 07 Lund / SE
Opponent's representative
Roques, Sarah Elizabeth
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ / GB
22.05.2003Invitation to proprietor to file observations on the notice of opposition
01.07.2004Reply of patent proprietor to notice(s) of opposition
23.03.2005Despatch of communication that the patent will be revoked
02.04.2005Legal effect of revocation of patent [2005/23]
Request for further processing for:28.12.2001Request for further processing filed
28.12.2001Full payment received (date of receipt of payment)
Request granted
14.01.2002Decision despatched
27.08.1998Request for further processing filed
27.08.1998Full payment received (date of receipt of payment)
Request granted
11.09.1998Decision despatched
26.09.1996Request for further processing filed
26.09.1996Full payment received (date of receipt of payment)
Request deemed not to be filed
15.10.1996Decision despatched
Fees paidRenewal fee
22.01.1993Renewal fee patent year 03
25.11.1993Renewal fee patent year 04
16.01.1995Renewal fee patent year 05
26.01.1996Renewal fee patent year 06
21.01.1997Renewal fee patent year 07
22.12.1997Renewal fee patent year 08
25.01.1999Renewal fee patent year 09
14.12.1999Renewal fee patent year 10
31.01.2001Renewal fee patent year 11
29.01.2002Renewal fee patent year 12
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT17.07.2002
BE17.07.2002
CH17.07.2002
GR17.07.2002
LI17.07.2002
NL17.07.2002
DK17.10.2002
LU17.01.2003
ES30.01.2003
IT17.01.2005
[2007/34]
Former [2004/39]AT17.07.2002
BE17.07.2002
CH17.07.2002
GR17.07.2002
LI17.07.2002
NL17.07.2002
DK17.10.2002
LU17.01.2003
ES30.01.2003
Former [2004/04]AT17.07.2002
BE17.07.2002
CH17.07.2002
GR17.07.2002
LI17.07.2002
NL17.07.2002
DK17.10.2002
ES30.01.2003
Former [2003/48]AT17.07.2002
BE17.07.2002
CH17.07.2002
GR17.07.2002
LI17.07.2002
NL17.07.2002
DK17.10.2002
Former [2003/45]AT17.07.2002
CH17.07.2002
GR17.07.2002
LI17.07.2002
NL17.07.2002
DK17.10.2002
Former [2003/31]AT17.07.2002
CH17.07.2002
GR17.07.2002
LI17.07.2002
NL17.07.2002
Former [2003/20]GR17.07.2002
NL17.07.2002
Former [2003/07]NL17.07.2002
Documents cited:Search[X]  - CELLULAR IMMUNOLOGY, vol. 97, no. 2, February 1986, pages 371-385; C.D. PLATSOUCAS et al.: "Immunomodulation of human leukocytes by staphylococcal enterotoxin A: augmentation of natural killer cells and induction of suppressor cells"
International search[Y]WO8802632  (HARVARD COLLEGE [US], et al)
 [X]  - Biological Abstracts, Volume 88, No. 7, issued 01 October 1989, SHCHEGLOVITOVA et al., "Effect of Staphylococcus enterotoxin a on the development of Lewis lung carcinoma in mice". See Abstract 75810, EKSP ONKOL, 11(1): 73-74.
 [X]  - Biological Abstracts, Volume 88, No. 8, issued 10 October 1989, SHCHEGLOVITOVAL et al, "Effect of Staphylococcal enterotoxin A-sensitized spleen cells on the metastasizing of mouse Lewis lung carcinoma". See Abstract 87362, EKSP ONKOL, II(2): 54-57.
 [X]  - Biological Abstracts, Volume 84, No. 5 issued 01 September 1987, SHCHEGLOVITOVA et al., "Nonspecific antitumor activity of staphylococcal enterotoxins". See Abstract 48345, EKSP ONKOL, 9(1): 28-30.
 [X]  - Infection and Immunity, Vol. 57, No. 7, issued July 1989, PENARRUBIA et al., "Selective Proliferation of Nautural killer Cells among Monoate Depleted Peripheral Blood Mononuclear Cells as a Result of Stimulation with Staphylococcal Enterotoxin B" pgs. 2057-2065. See "introduction".
 [Y]  - Proc. Natl. Acad. Sci., Vol. 72, No. 9, issued September 1975, CARSWELL et al., "An endotoxin-induced serum factor that causes necrosis of tumors" pgs. 3666-3670. See entire document.
 [Y]  - Infection and Immunity, Vol. 57, No. 1, issued January 1989, FAST et al. "Toxic Shock Syndrome Associated Staphylococcal and Streptococcal Pyrogenic Toxins are Potent Inducers of Tumor Necrosis Factor Production", pgs. 291-294. See Abstract.
Examination   - NATURE 339 (1989) 221-3; CELLULAR IMMUNOLOGY 122 (1989) 108-121 J EXP MED 171 (1990) 455-464; J IMMUNOL 144 (1990) 2473-9
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.