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Extract from the Register of European Patents

EP About this file: EP0522091

EP0522091 - USE OF A MBP PEPTIDE FOR THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF MULTIPLE SCLEROSIS [Right-click to bookmark this link]
Former [1993/02]MULTIPLE SCLEROSIS T-CELL RECEPTOR
[2001/09]
StatusNo opposition filed within time limit
Status updated on  18.10.2002
Database last updated on 06.07.2024
Most recent event   Tooltip19.10.2007Correction of patent specificationpublished on 21.11.2007  [2007/47]
Applicant(s)For all designated states
BRIGHAM AND WOMEN'S HOSPITAL
75 Francis Street Boston
Massachusetts 02115 / US
For all designated states
AUTOIMMUNE, INC.
1199 Madia Street
Pasadena, CA 91103 / US
[N/P]
Former [2002/01]For all designated states
BRIGHAM AND WOMEN'S HOSPITAL
75 Francis Street
Boston, Massachusetts 02115 / US
For all designated states
AUTOIMMUNE, INC.
1199 Madia Street
Pasadena, CA 91103 / US
Former [1993/02]For all designated states
BRIGHAM AND WOMEN'S HOSPITAL
75 Francis Street
Boston, Massachusetts 02115 / US
For all designated states
AUTOIMMUNE, INC.
1041 Third Avenue
New York, NY 10021 / US
Inventor(s)01 / WUCHERPFENNING, Kai, W.
117 Park Drive
Boston, MA 02215 / US
02 / WEINER, Howard, L.
114 Somerset Road
Brookline, MA 02146 / US
03 / HAFLER, David, Allen
110 Forest Avenue
West Newton, MA 02165 / US
[1993/02]
Representative(s)Grünecker Patent- und Rechtsanwälte PartG mbB
Leopoldstrasse 4
80802 München / DE
[N/P]
Former [1993/02]Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät
Maximilianstrasse 58
D-80538 München / DE
Application number, filing date91910085.929.03.1991
[1993/02]
WO1991US02218
Priority number, dateUS1990050255930.03.1990         Original published format: US 502559
[1993/02]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9115225
Date:17.10.1991
Language:EN
[1991/24]
Type: A1 Application with search report 
No.:EP0522091
Date:13.01.1993
Language:EN
The application published by WIPO in one of the EPO official languages on 17.10.1991 takes the place of the publication of the European patent application.
[1993/02]
Type: B1 Patent specification 
No.:EP0522091
Date:12.12.2001
Language:EN
[2001/50]
Type: B9 Corrected patent specification 
No.:EP0522091
Date:21.11.2007
[2007/47]
Search report(s)International search report - published on:US17.10.1991
(Supplementary) European search report - dispatched on:EP05.04.1993
ClassificationIPC:C12N5/08, C12N5/06, A61K38/00, C12Q1/68
[2001/10]
CPC:
C12Q1/6883 (EP); A61K39/0008 (EP); A61P25/00 (EP);
A61P25/28 (EP); A61P29/00 (EP); A61P37/06 (EP);
C07K14/7051 (EP); C12Q1/6881 (EP); A61K38/00 (EP);
C12Q2600/156 (EP); C12Q2600/172 (EP) (-)
Former IPC [1993/21]C12N5/08, C12N5/06, A61K37/02, C12Q1/68
Former IPC [1993/02]A61K37/02, C12N5/06, C12N5/08, C12Q1/68
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IT,   LI,   LU,   NL,   SE [1993/02]
TitleGerman:VERWENDUNG EINES MBP PEPTIDES ZUR HERSTELLUNG EINES MEDIKAMENTES FÜR DIE BEHANDLUNG VON MULTIPLER SCLEROSE[2001/09]
English:USE OF A MBP PEPTIDE FOR THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF MULTIPLE SCLEROSIS[2001/09]
French:UTILISATION D'UN PEPTIDE DE MBP POUR LA PREPARATION D'UN MEDICAMENT POUR LE TRAITEMENT THERAPEUTIQUE DE LA SCLEROSE EN PLAQUES[2001/09]
Former [1993/02]BEI MULTIPLER SKLEROSE AUSGEPRÄGTER T-ZELL-REZEPTOR
Former [1993/02]MULTIPLE SCLEROSIS T-CELL RECEPTOR
Former [1993/02]RECEPTEUR DE LYMPHOCITES T SE MANIFESTANT DANS LA SCLEROSE EN PLAQUES
Entry into regional phase29.09.1992National basic fee paid 
29.09.1992Search fee paid 
29.09.1992Designation fee(s) paid 
29.09.1992Examination fee paid 
Examination procedure10.10.1991Request for preliminary examination filed
International Preliminary Examining Authority: DE
29.09.1992Examination requested  [1993/02]
24.04.1995Despatch of a communication from the examining division (Time limit: M04)
30.05.1995Reply to a communication from the examining division
14.08.1995Despatch of a communication from the examining division (Time limit: M06)
13.02.1996Reply to a communication from the examining division
19.07.1996Despatch of a communication from the examining division (Time limit: M06)
03.03.1997Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
13.05.1997Reply to a communication from the examining division
17.03.1998Despatch of a communication from the examining division (Time limit: M06)
28.09.1998Reply to a communication from the examining division
23.10.1998Despatch of a communication from the examining division (Time limit: M06)
30.04.1999Reply to a communication from the examining division
05.10.1999Despatch of a communication from the examining division (Time limit: M06)
02.03.2000Reply to a communication from the examining division
04.04.2000Despatch of a communication from the examining division (Time limit: M04)
11.08.2000Reply to a communication from the examining division
16.02.2001Despatch of communication of intention to grant (Approval: Yes)
18.06.2001Communication of intention to grant the patent
24.09.2001Fee for grant paid
24.09.2001Fee for publishing/printing paid
Opposition(s)13.09.2002No opposition filed within time limit [2002/49]
Request for further processing for:13.05.1997Request for further processing filed
13.05.1997Full payment received (date of receipt of payment)
Request granted
30.05.1997Decision despatched
Fees paidRenewal fee
26.02.1993Renewal fee patent year 03
24.02.1994Renewal fee patent year 04
20.02.1995Renewal fee patent year 05
08.03.1996Renewal fee patent year 06
12.03.1997Renewal fee patent year 07
10.03.1998Renewal fee patent year 08
11.03.1999Renewal fee patent year 09
13.03.2000Renewal fee patent year 10
16.03.2001Renewal fee patent year 11
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Documents cited:Search[A]  - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE USA vol. 85, no. 22, 15 November 1988, WASHINGTON DC, US pages 8608 - 8612 K. SAKAI ET AL. 'Involvement of distinct murine T-cell receptors in the autoimmune encephalitogenic response to nested epitopes of myelin basic protein.'
International search[X]  - Nature, Vol. 341, issued 12 October 1989, VANDENBARK et al., "Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis", pages 541-544, see page 542.
 [XP]  - Science, Vol. 248, issued 1990, WUCHERPFENNIG et al., "Shares human T-cell Receptor V-beta usage to immunodominant regions of myclin basis protein", see page 4958, Abstract No. 90:334456.
 [XP]  - J. Exp. Med., Vol. 171, issued June 1990, ZALLER et al., "Prevention and Treatment of Murine Experimental Allergic Encephalomyelitis with T-cell Receptor V.B. Specific Antibodies", pages 1943-1955. See entire document.
 [YP]  - Journal of Immunology, Vol. 144, No. 12, issued 15 June 1990, HASHIM et al., "Antibodies Specific for VB8 Receptor Peptide Suppress Experimental Autoimmune Encephalomyelitis", pages 4621-4627, see entire document.
Examination   - JOURNAL OF IMMUNOLOGY, vol. 144, no. 12, 15 June 1990; HASHIM et al., pp. 4621-4627
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.