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Extract from the Register of European Patents

EP About this file: EP0583566

EP0583566 - Process for the preparation of glycine-conjugated bile acids [Right-click to bookmark this link]
Former [1994/08]Process for the preparation of glycine-conjugated bile acids and relative pharmaceutical compositions useful for treating hepatic insufficiency
[1997/34]
StatusNo opposition filed within time limit
Status updated on  30.07.1999
Database last updated on 13.07.2024
Most recent event   Tooltip28.12.2007Lapse of the patent in a contracting state
New state(s): IT		published on 30.01.2008  [2008/05]
Applicant(s)For all designated states
ERREGIERRE INDUSTRIA CHIMICA Spa
via F. Baracca 19
I-24060 San Paolo d'Argon (BG) / IT
[1994/08]
Inventor(s)01 / Bonaldi, Antonio
Via A. Frank 4
I-24060 Chiuduno / IT
02 / Molinari, Egidio
Via A. Manzoni 12
I-22030 Longone Al Segrino (Como) / IT
03 / Roda, Aldo
Via Alamandini 9/2
I-40136 Bologna / IT
[1998/39]
Former [1994/08]01 / Bonaldi, Antonio
Via A. Frank 4
I-24060 Chiuduno / IT
02 / Molinari, Egidio
Via A. Manzoni 12
I-22030 Longone Al Segrino (Como) / IT
03 / Roda, AldoEgidio
Via Alamandini 9/2
I-40136 Bologna / IT
Representative(s)Gervasi, Gemma, et al
Notarbartolo & Gervasi S.p.A.
Viale Achille Papa, 30
20149 Milano / IT
[N/P]
Former [1994/40]Gervasi, Gemma, Dr., et al
NOTARBARTOLO & GERVASI Srl Viale Bianca Maria 33
I-20122 Milano / IT
Former [1994/08]Gervasi, Gemma, Dr.
NOTARBARTOLO & GERVASI Srl 33, Viale Bianca Maria
I-20122 Milano / IT
Application number, filing date93109377.711.06.1993
[1994/08]
Priority number, dateIT1992MI0192404.08.1992         Original published format: IT MI921924
[1994/08]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP0583566
Date:23.02.1994
Language:EN
[1994/08]
Type: A3 Search report 
No.:EP0583566
Date:27.12.1995
Language:EN
[1995/52]
Type: B1 Patent specification 
No.:EP0583566
Date:23.09.1998
Language:EN
[1998/39]
Search report(s)(Supplementary) European search report - dispatched on:EP08.11.1995
ClassificationIPC:C07J41/00, A61K31/575, // C07J9/00
[1994/08]
CPC:
C07J41/0061 (EP); A61K31/575 (EP); A61P1/16 (EP);
C07J9/005 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1994/08]
TitleGerman:Verfahren zur Herstellung Glycin-konjugierter Gallensäure[1997/34]
English:Process for the preparation of glycine-conjugated bile acids[1997/34]
French:Procédé de préparation des acides biliaires conjugés à glycine[1997/34]
Former [1994/08]Verfahren zur Herstellung Glycin-konjugierter Gallensäure und relative pharmazeutische Präparate zur Behandlung hepatischer Insuffizienz
Former [1994/08]Process for the preparation of glycine-conjugated bile acids and relative pharmaceutical compositions useful for treating hepatic insufficiency
Former [1994/08]Procédé de préparation des acides biliaires conjugés à glycine et compositions pharmaceutiques Relatives, utiles dans le traitement des insuffisances hepatiques
Examination procedure13.06.1996Examination requested  [1996/34]
29.01.1997Despatch of a communication from the examining division (Time limit: M04)
02.05.1997Reply to a communication from the examining division
08.07.1997Despatch of communication of intention to grant (Approval: Yes)
07.11.1997Communication of intention to grant the patent
30.01.1998Fee for grant paid
30.01.1998Fee for publishing/printing paid
Opposition(s)24.06.1999No opposition filed within time limit [1999/37]
Fees paidRenewal fee
23.06.1995Renewal fee patent year 03
22.06.1996Renewal fee patent year 04
23.06.1997Renewal fee patent year 05
25.06.1998Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT23.09.1998
BE23.09.1998
CH23.09.1998
ES23.09.1998
FR23.09.1998
GR23.09.1998
IT23.09.1998
LI23.09.1998
NL23.09.1998
DK23.12.1998
PT23.12.1998
SE23.12.1998
DE24.12.1998
GB11.06.1999
IE11.06.1999
LU11.06.1999
[2008/05]
Former [2006/14]AT23.09.1998
BE23.09.1998
CH23.09.1998
ES23.09.1998
FR23.09.1998
GR23.09.1998
LI23.09.1998
NL23.09.1998
DK23.12.1998
PT23.12.1998
SE23.12.1998
DE24.12.1998
GB11.06.1999
IE11.06.1999
LU11.06.1999
Former [2004/39]AT23.09.1998
BE23.09.1998
CH23.09.1998
ES23.09.1998
GR23.09.1998
LI23.09.1998
NL23.09.1998
DK23.12.1998
PT23.12.1998
SE23.12.1998
DE24.12.1998
FR19.02.1999
GB11.06.1999
IE11.06.1999
LU11.06.1999
Former [2003/45]AT23.09.1998
BE23.09.1998
CH23.09.1998
ES23.09.1998
GR23.09.1998
LI23.09.1998
NL23.09.1998
DK23.12.1998
PT23.12.1998
SE23.12.1998
DE24.12.1998
FR19.02.1999
GB11.06.1999
IE11.06.1999
Former [2003/07]AT23.09.1998
BE23.09.1998
CH23.09.1998
ES23.09.1998
GR23.09.1998
LI23.09.1998
NL23.09.1998
PT23.12.1998
SE23.12.1998
DE24.12.1998
FR19.02.1999
GB11.06.1999
IE11.06.1999
Former [2002/25]AT23.09.1998
BE23.09.1998
CH23.09.1998
ES23.09.1998
GR23.09.1998
LI23.09.1998
PT23.12.1998
SE23.12.1998
DE24.12.1998
FR19.02.1999
GB11.06.1999
IE11.06.1999
Former [2001/23]AT23.09.1998
BE23.09.1998
CH23.09.1998
GR23.09.1998
LI23.09.1998
PT23.12.1998
SE23.12.1998
DE24.12.1998
FR19.02.1999
GB11.06.1999
IE11.06.1999
Former [2001/09]AT23.09.1998
BE23.09.1998
CH23.09.1998
LI23.09.1998
PT23.12.1998
SE23.12.1998
DE24.12.1998
FR19.02.1999
GB11.06.1999
IE11.06.1999
Former [2001/07]AT23.09.1998
BE23.09.1998
CH23.09.1998
LI23.09.1998
PT23.12.1998
SE23.12.1998
DE24.12.1998
FR19.02.1999
GB11.06.1999
Former [1999/36]AT23.09.1998
BE23.09.1998
CH23.09.1998
LI23.09.1998
PT23.12.1998
SE23.12.1998
DE24.12.1998
FR19.02.1999
Former [1999/34]AT23.09.1998
BE23.09.1998
CH23.09.1998
LI23.09.1998
PT23.12.1998
SE23.12.1998
DE24.12.1998
Former [1999/32]BE23.09.1998
CH23.09.1998
LI23.09.1998
PT23.12.1998
SE23.12.1998
DE24.12.1998
Former [1999/30]BE23.09.1998
CH23.09.1998
LI23.09.1998
PT23.12.1998
DE24.12.1998
Former [1999/29]BE23.09.1998
CH23.09.1998
LI23.09.1998
PT23.12.1998
Former [1999/27]BE23.09.1998
CH23.09.1998
LI23.09.1998
Former [1999/22]CH23.09.1998
LI23.09.1998
Documents cited:Search[X]JPS5126870  ;
 [Y]EP0046523  (US HEALTH [US]) [Y] 1-10 * page 9 *;
 JPS5826360  [ ] (SONY CORP);
 [Y]EP0400695  (PRODOTTI CHIMICI ALIMENTARI [IT]) [Y] 1-10 * example 1 *;
 [X]  - A. BELLINI ET AL., "Antimicrobial Activity of Cholane Compounds", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.CHIMICA THERAPEUTICA, PARIS, FR, (1983), vol. 18, no. 2, pages 185 - 190, XP002073925 [X] 1-10 * page 185, column 2 - page 186, column 2 *
 [Y]  - J. GOTO ET AL., "Studies on the Analysis of Bile Acids. Preparation of 3-Glucuronides of 7- and 12-Oxo Bile AScids", CHEMICAL AND PHARMACEUTICAL BULLETIN, TOKYO, JP, (198212), vol. 30, no. 12, pages 4422 - 4428, XP002073926 [Y] 1-10 * page 4425 - page 4427 *

DOI:   http://dx.doi.org/10.1248/cpb.30.4422
 [A]  - HOFMANN A.F. ET AL., "The Biological Utility of Bile Acid Conjugation with Glycine or Taurine", FALK SYMPOSIUM (PUBL. 1985), (1984), vol. 40, pages 245 - 264, XP002073927 [A] 1-10 * the whole document *
 [X]  - H. IGIMI ET AL., "Cholesterol gallstone dissolution in bile: dissolution kinetics of crystalline (anhydrate and monohydrate) cholesterol with chenodeoxycholate, ursodeoxycholate and their glycine and taurine conjugates.", J. LIPID RES., (1981), vol. 22, no. 2, pages 254 - 270, XP002073928 [X] 11-16 * abstract *
 [X]  - R. RAEDSCH ET AL., "Kinetics of cholesterol gallstone dissolution by glycocheno-,glycoursodeoxycholic acid, end mixtures thereof in vitro.", Z. GASTROENTEROLOGIE, (1981), vol. 19, no. 4, pages 159 - 163, XP002073929 [X] 11-16 * summary *
 [X]  - DATABASE WPI, 1, Derwent World Patents Index, vol. 76, no. 16, Database accession no. 76-29269x, XP002073930 & JPS5126870 A 19760306 (EISAI KK) [X] 11-16 * abstract *
ExaminationEP0100983
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.