EP0583579 - New 17-hydroxyiminomethyl-5beta, 14beta-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 09.10.1998 Database last updated on 15.06.2024 | Most recent event Tooltip | 09.10.1998 | No opposition filed within time limit | published on 25.11.1998 [1998/48] | Applicant(s) | For all designated states SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Viale Shakespeare, 47 00144 Roma / IT | [N/P] |
Former [1997/49] | For all designated states Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Viale Shakespeare, 47 00144 Roma / IT | ||
Former [1994/08] | For all designated states Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Viale Shakespeare, 47 I-00144 Roma / IT | Inventor(s) | 01 /
Cerri, Alberto 7, Monte San Michele I-20060 Gessate (Milan) / IT | 02 /
Bernardi, Luigi 30, Via Pinerolo I-20151 Milan / IT | 03 /
Bianchi, Giuseppe 5, Via Vigoni I-20124 Milan / IT | 04 /
Florio, Monica 32 Via Don Sturzo I-20091 Bresso / IT | 05 /
Folpini, Elena 6, Via della Rondine I-20147 Milan / IT | 06 /
Melloni, Piero 1, Via Centurelli I-20091 Bresso (Milan) / IT | [1994/19] |
Former [1994/08] | 01 /
Cerri, Alberto 7, Monte San Michele I-20060 Gessate (Milan) / IT | ||
02 /
Bernardi, Luigi 30, Via Pinerolo I-20151 Milan / IT | |||
03 /
Bianchi, Giuseppe 5, Via Vigoni I-20124 Milan / IT | |||
04 /
Florio, Monica 32 Via Don Sturza I-20091 Bresso / IT | |||
05 /
Folpini, Elena 6, Via della Rondine I-20147 Milan / IT | |||
06 /
Melloni, Piero 1, Via Centurelli I-20091 Bresso (Milan) / IT | Representative(s) | Fassi, Aldo, et al Hoffmann-Eitle & Partner, Patent-und Rechtsanwälte, Postfach 81 04 20 81904 München / DE | [N/P] |
Former [1994/08] | Fassi, Aldo, et al Hoffmann-Eitle & Partner, Patent-und Rechtsanwälte, Postfach 81 04 20 D-81904 München / DE | Application number, filing date | 93110189.3 | 25.06.1993 | [1994/08] | Priority number, date | DE19924227605 | 20.08.1992 Original published format: DE 4227605 | [1994/08] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP0583579 | Date: | 23.02.1994 | Language: | EN | [1994/08] | Type: | A3 Search report | No.: | EP0583579 | Date: | 22.03.1995 | Language: | EN | [1995/12] | Type: | B1 Patent specification | No.: | EP0583579 | Date: | 03.12.1997 | Language: | EN | [1997/49] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 06.02.1995 | Classification | IPC: | C07J41/00, C07J43/00, A61K31/56, A61K31/57, A61K31/58 | [1994/08] | CPC: |
C07J41/0016 (EP,US);
C07J41/0044 (KR);
A61P9/00 (EP);
A61P9/04 (EP);
A61P9/12 (EP);
C07J41/0005 (EP,US);
| Designated contracting states | AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1994/08] | Title | German: | Neue 17-Hydroxyiminomethyl-5beta, 14beta-Androstan-Derivate, kardioaktives Verfahren zu ihrer Herstellung und pharmazeutische Präparate davon | [1994/08] | English: | New 17-hydroxyiminomethyl-5beta, 14beta-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same | [1994/08] | French: | Nouveaux 17-hydroxyiminométhyl-5béta, 14béta-androstanes cardioactifs, procédé pour leur production et les compositions pharmaceutiques les renfermant | [1994/08] | Examination procedure | 23.05.1995 | Examination requested [1995/29] | 06.10.1995 | Despatch of a communication from the examining division (Time limit: M04) | 23.01.1996 | Reply to a communication from the examining division | 08.05.1996 | Despatch of a communication from the examining division (Time limit: M02) | 17.06.1996 | Reply to a communication from the examining division | 14.03.1997 | Despatch of communication of intention to grant (Approval: No) | 04.06.1997 | Despatch of communication of intention to grant (Approval: later approval) | 09.06.1997 | Communication of intention to grant the patent | 02.09.1997 | Fee for grant paid | 02.09.1997 | Fee for publishing/printing paid | Opposition(s) | 04.09.1998 | No opposition filed within time limit [1998/48] | Fees paid | Renewal fee | 27.06.1995 | Renewal fee patent year 03 | 28.06.1996 | Renewal fee patent year 04 | 27.06.1997 | Renewal fee patent year 05 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [DX] - B. TESTA, ADVANCES IN DRUG RESEARCH, VOLUME 19, LONDON, GB, ACADEMIC PRESS, (1990) [DX] 1-3 * pages 535-545, particularly pages 538-540, compound CCXXX * | [PX] - Templeton J F et al, "Synthesis of 20.alpha.- and 20.beta.-acetamido, amino, nitro, and hydroxy derivatives of 14-hydroxy-5.beta.,14.beta.-pregnane 3.beta.-glycosides: pregnanes that bind to the digitalis receptor", JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 1, LETCHWORTH GB, (19921007), no. 19, pages 2503 - 2517 [PX] 1-4 * page 2504; examples 2b,c * | [PA] - Templeton J F et al, "Synthesis of 20-hydroxy-, 20-amino-, and 20-nitro-14-hydroxy-21-nor -5.beta.,14.beta.-pregnane C-3 glycosides and related derivatives: structure-activity relationships of pregnanes that bind to the digitalis receptor", JOURNAL OF MEDICINAL CHEMISTRY, WASHINGTON US, (19930108), vol. 36, no. 1, doi:doi:10.1021/jm00053a006, pages 42 - 45, XP002001546 [PA] 1-4 * page 43; examples 7a,b * DOI: http://dx.doi.org/10.1021/jm00053a006 |