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Extract from the Register of European Patents

EP About this file: EP0661972

EP0661972 - USE OF SPIPERONE OR SPIPERONE DERIVATIVES AS IMMUNOSUPPRESSANT AGENTS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  05.11.1999
Database last updated on 26.06.2024
Most recent event   Tooltip05.11.1999Application deemed to be withdrawnpublished on 22.12.1999 [1999/51]
Applicant(s)For all designated states
BETH ISRAEL HOSPITAL
330 Brookline Avenue Boston
Massachusetts 02215 / US
[N/P]
Former [1995/28]For all designated states
BETH ISRAEL HOSPITAL
330 Brookline Avenue
Boston Massachusetts 02215 / US
Inventor(s)01 / SHARPE, Richard, J.
30 Melbourne Avenue
Newtonville, MA 02160 / US
02 / ARNDT, Kenneth, A.
104 Lake Avenue
Newton Centre, MA 02159 / US
03 / GALLI, Stephen, J.
9 Lakeview Terrace
Winchester, MA 01890 / US
04 / MELTZER, Peter, C.
8 Rumford Road
Lexington, MA 02173 / US
05 / RAZDAN, Raj, K.
76 Lawrence Lane
Belmont, MA 02178 / US
06 / SARD, Howard, P.
67 Hillside Avenue
Arlington, MA 02174 / US
[1995/28]
Representative(s)Bassett, Richard Simon, et al
Potter Clarkson LLP The Belgrave Centre
Talbot Street
Nottingham NG1 5GG / GB
[N/P]
Former [1995/28]Bassett, Richard Simon, et al
ERIC POTTER & CLARKSON St. Mary's Court St. Mary's Gate
Nottingham NG1 1LE / GB
Application number, filing date93902752.023.12.1992
[1995/28]
WO1992US11205
Priority number, dateUS1991081528327.12.1991         Original published format: US 815283
US1992083142905.02.1992         Original published format: US 831429
US1992089353604.06.1992         Original published format: US 893536
US1992089353404.06.1992         Original published format: US 893534
[1995/28]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9312789
Date:08.07.1993
Language:EN
[1993/16]
Type: A1 Application with search report 
No.:EP0661972
Date:12.07.1995
Language:EN
The application published by WIPO in one of the EPO official languages on 08.07.1993 takes the place of the publication of the European patent application.
[1995/28]
Search report(s)International search report - published on:US08.07.1993
(Supplementary) European search report - dispatched on:EP27.10.1994
ClassificationIPC:A61K31/44, A61K31/435
[1995/28]
CPC:
A61K31/435 (EP); A61P37/06 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1995/28]
TitleGerman:VERWENDUNG VON SPIPERON UND SPIPERONDERIVATEN ALS IMMUNSUPPRESSIVE WIRKSTOFFE[1995/28]
English:USE OF SPIPERONE OR SPIPERONE DERIVATIVES AS IMMUNOSUPPRESSANT AGENTS[1995/28]
French:UTILISATION DE LA SPIPERONE OU DE DERIVES DE LA SPIPERONE COMME AGENTS IMMUNODEPRESSEURS[1995/28]
Entry into regional phase27.07.1994National basic fee paid 
27.07.1994Search fee paid 
27.07.1994Designation fee(s) paid 
27.07.1994Examination fee paid 
Examination procedure26.07.1993Request for preliminary examination filed
International Preliminary Examining Authority: DE
27.07.1994Examination requested  [1995/28]
16.04.1998Despatch of a communication from the examining division (Time limit: M06)
22.10.1998Reply to a communication from the examining division
01.07.1999Application deemed to be withdrawn, date of legal effect  [1999/51]
29.07.1999Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [1999/51]
Fees paidRenewal fee
22.12.1994Renewal fee patent year 03
29.03.1996Renewal fee patent year 04
11.12.1996Renewal fee patent year 05
12.12.1997Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
31.12.199504   M06   Fee paid on   29.03.1996
31.12.199807   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XA]WO9113622  (BETH ISRAEL HOSPITAL [US]) [X] 1-17,19-28 * the whole document * [A] 18,29;
 [X]WO9102527  (BETH ISRAEL HOSPITAL [US]) [X] 1-4,8-10,13,14,16,21-23,26 * abstract * * page 10, line 1 - page 11, line 20 * * page 18, line 30 - page 19, line 28; examples 2-4; claims 1-5,8-14,16-20 *
 [T]  - A. CHANDRASEKAR ET AL., "SPIPERONE METHYL AMMONIUM BROMIDE INHIBITS CUTANEOUS CONTACT HYPERSENSITIVITY IN THE MOUSE", CLINICAL RESEARCH, (1993), vol. 41, no. 3, page 606A [T] 1-29 * the whole document *
 [PX]  - R.J. SHARPE ET AL., "INHIBITION OF CUTANEOUS CONTACT HYPERSENSITIVITY IN THE MOUSE WITH SYSTEMIC OR TOPICAL SPIPERONE: TOPICAL APPLICATION OF SPIPERONE PRODUCES LOCAL IMMUNOSUPPRESSION WITHOUT INDUCING SYSTEMIC NEUROLEPTIC EFFECTS", THE JOURNAL OF INVESTIGATIVE DERMATOLOGY, (199211), vol. 99, no. 5, pages 594 - 600 [PX] 1-4,8-10,13,14,16,22,23,28 * the whole document *
 [A]  - E. OKKERSE ET AL., "IDENTIFICATION OF CRYSTALLINE DERIVATIVES OF BUTYROPHENONES BY X-RAY DIFFRACTION: ...", JOURNAL OF THE ASSOCIATION OF OFFICIAL ANALYTICAL CHEMISTS, (1971), vol. 54, no. 6, pages 1406 - 1419 [A] 5-7,18,29 * the whole document *
 [DA]  - S.M. MOERLEIN ET AL., "EFFECT OF LIPOPHILICITY ON THE IN VIVO LOCALIZATION OF RADIOLABELLED SPIPERONE ANALOGUES", INTERNATIONAL JOURNAL OF NUCLEAR MEDICINE AND BIOLOGY, (1985), vol. 12, no. 5, pages 353 - 356 [DA] 1-29 * the whole document *
International search[X]US3155669  ;
 [X]US4839342
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.