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Extract from the Register of European Patents

EP About this file: EP0643682

EP0643682 - PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 2-SUBSTITUTED BENZALDEHYDES [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 21.02.1997 Database last updated on 05.08.2024
Most recent event Tooltip	21.02.1997	Application deemed to be withdrawn	published on 09.04.1997 [1997/15]
Applicant(s)	For all designated states SMITHKLINE BEECHAM CORPORATION One Franklin Plaza P.O. Box 7929 Philadelphia, PA 19101 / US
	For all designated states SMITHKLINE BEECHAM PLC New Horizons Court Brentford Middlesex TW8 9BD / GB
	[N/P]
Former [1995/12]	For all designated states SMITHKLINE BEECHAM CORPORATION P.O. Box 7929 1 Franklin Plaza Philadelphia Pennsylvania 19101 / US
	For all designated states SMITHKLINE BEECHAM PLC New Horizons Court Brentford, Middlesex TW8 9BD / GB
Inventor(s)	01 / GOMBATZ, Kerry, Joseph 606 Westbourne Road West Chester, PA 19382 / US
	02 / FORTH, Michael Anthony, SmithKline Beecham Pharm. Old Powder Mills, Near Leigh Tonbridge, Kent TN11 9AN / GB
	03 / HAYES, Jerome Francis, SmithKline Beecham Pharm. Old Powder Mills, Near Leigh Tonbridge, KentTN 11 t9AN / GB
	04 / MITCHELL, Michael Barry, SmithKline Beecham Pharm. Old Powder Mills, Near Leigh Tonbridge, Kent TN11 9AN / GB
	05 / SMITH, Stephen Alexander, SmithKline Beecham Pharm Old Powder Mills, Near Leigh Tonbridge, Kent TN11 9AN / GB
	[1995/12]
Representative(s)	Connell, Anthony Christopher GlaxoSmithKline Global Patents (CN925.1) 980 Great West Road Brentford, Middlesex TW8 9GS / GB
	[N/P]
Former [1995/12]	Connell, Anthony Christopher SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road Brentford, Middlesex TW8 9BD / GB
Application number, filing date	93909170.8	25.03.1993
	[1995/12]
	WO1993US02803
Priority number, date	US19920858384	25.03.1992 Original published format: US 858384
	[1995/12]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9319033
	Date:	30.09.1993
	Language:	EN
	[1993/24]
	Type:	A1 Application with search report
	No.:	EP0643682
	Date:	22.03.1995
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 30.09.1993 takes the place of the publication of the European patent application.
	[1995/12]
Search report(s)	International search report - published on:	US	30.09.1993
	(Supplementary) European search report - dispatched on:	EP	21.04.1995
Classification	IPC:	C07C45/00, C07C45/42, C07C249/02, C07C251/16, C07D307/52, C07D307/58, C07D307/64, C07D333/32, C07D333/34	[1995/12]
	CPC:	C07C251/86 (EP); C07C45/00 (KR); C07C251/24 (EP); C07C45/516 (EP); C07C47/546 (EP)
	C-Set:	C07C45/516, C07C47/546 (EP)
Designated contracting states	AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1995/12]
Title	German:	VERFAHREN UND ZWISCHENPRODUKTE ZUR HERSTELLUNG VON 2-SUBSTITUIERTEN BENZALDEHYDEN	[1995/12]
	English:	PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 2-SUBSTITUTED BENZALDEHYDES	[1995/12]
	French:	PROCEDES ET INTERMEDIAIRES POUR LA PREPARATION DE BENZALDEHYDES 2-SUBSTITUTES	[1995/12]
Entry into regional phase	25.10.1994	National basic fee paid
	25.10.1994	Search fee paid
	25.10.1994	Designation fee(s) paid
	25.10.1994	Examination fee paid
Examination procedure	29.09.1993	Request for preliminary examination filed International Preliminary Examining Authority: US
	25.10.1994	Examination requested [1995/12]
	29.05.1996	Despatch of a communication from the examining division (Time limit: M04)
	01.10.1996	Application deemed to be withdrawn, date of legal effect [1997/15]
	08.11.1996	Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [1997/15]
Fees paid	Renewal fee
	13.03.1995	Renewal fee patent year 03
	Penalty fee
	Penalty fee Rule 85a EPC 1973
	07.02.1994	AT M01 Not yet paid
	07.02.1994	BE M01 Not yet paid
	07.02.1994	CH M01 Not yet paid
	07.02.1994	DE M01 Not yet paid
	07.02.1994	DK M01 Not yet paid
	07.02.1994	ES M01 Not yet paid
	07.02.1994	FR M01 Not yet paid
	07.02.1994	GB M01 Not yet paid
	07.02.1994	GR M01 Not yet paid
	07.02.1994	IE M01 Not yet paid
	07.02.1994	IT M01 Not yet paid
	07.02.1994	LI M01 Not yet paid
	07.02.1994	LU M01 Not yet paid
	07.02.1994	MC M01 Not yet paid
	07.02.1994	NL M01 Not yet paid
	07.02.1994	PT M01 Not yet paid
	Additional fee for renewal fee
	31.03.1996	04 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[ ] - No further relevant documents disclosed
	International search	[Y]US3466164 (GAETANO JOSEPH F DE, et al);
		[Y]US3637851 (RUMANOWSKI EDMUND J);
		[Y]US3910944 (GALL MARTIN);
		[X]US4198349 (DOUGLAS GEORGE H [US], et al);
		[Y]US4231962 (REINEHR DIETER, et al);
		[XY]EP0217269 (BAYER AG [DE]);
		[Y]US4820719 (GLEASON JOHN G [US], et al)
		[Y] - J. Org. Chem., 1984, Vol. 49, WATENABLE et al., "Ortho-Lithiated Tertiary Benzamides, etc.", pp-742-749, see esp. schemes I-III on page 743 and definition for 2.
		[Y] - J. Org. Chem., 1965, Vol. 41, No. 9, ZIEGLER et al., "Substitution Reactions of Specifically Ortho-Metalated Piperonyl Cyclohexylimine", pp. 1564-6, see esp. last paragraph, left col., pg. 1564.
		[Y] - J. Org. Chem., 1975, Vol. 40, No. 13, GECHWEND et al., "Ortho-Lithiation of Aryloxazolines", pp. 2008-9, see esp. figures 1-3 on page 2008.
		[Y] - Tetrahedron Letters, 1978, No. 51, DE SILVA et al., "Directed Lithiation of N, N-Diethylbenzamides, etc.", pp. 5107-10, see esp. pg. 5108, lines 1 and 2 of the text.
		[Y] - Advanced Organic Chemistry, 1977, second edition, March, J., pp. 805-7, see esp. page 806, top.
		[X] - J. Org. Chem., 1978, Vol. 43, No. 21, MURAHASHI et al., "Reactions of Cyclometallated Palladium Complexes with Organolithium Compounds or Grignand Reagents", pp. 4099-106, see esp. compounds 5 and 7 on page 4099, 7 on pages 4100, and 28 and 29 on pages 4102.

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