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Extract from the Register of European Patents

EP About this file: EP0633892

EP0633892 - N-T-BUTYL-ANDROST-3,5-DIENE-17-beta-CARBOXAMIDE-3-CARBOXYLIC ACID POLYMORPH A [Right-click to bookmark this link]
Former [1995/03]N-T-BUTYL-ANDROST-3,5-DIENE-17$g(b)-CARBOXAMIDE-3-CARBOXYLIC ACID POLYMORPH A
[1998/33]
StatusNo opposition filed within time limit
Status updated on  31.03.2000
Database last updated on 19.07.2024
Most recent event   Tooltip31.03.2000No opposition filed within time limitpublished on 17.05.2000 [2000/20]
Applicant(s)For all designated states
SMITHKLINE BEECHAM CORPORATION
One Franklin Plaza P.O. Box 7929
Philadelphia, PA 19101 / US
[N/P]
Former [1999/21]For all designated states
SMITHKLINE BEECHAM CORPORATION
One Franklin Plaza, P.O. Box 7929
Philadelphia Pennsylvania 19101 / US
Former [1995/03]For all designated states
SMITHKLINE BEECHAM CORPORATION
P.O. Box 7929 1 Franklin Plaza
Philadelphia Pennsylvania 19101 / US
Inventor(s)01 / BAINE, Neil, Howard
216 Edgehill Road
Merion, PA 19066 / US
02 / HOLDER, Neville, Lewis
13 Clemson Road
Cherry Hill, NJ 08034 / US
03 / KLINE, Donald, Nathaniel
912 Mill Grove Drive
Audubon, PA 19403 / US
04 / WEBB, Robert, Lee
512 N. Veronica Road
West Chester, PA 19380 / US
05 / ZUBER, Gary, Edward
35 Skyline Drive
Audubon, PA 19403 / US
[1995/03]
Representative(s)Giddings, Peter John, et al
GlaxoSmithKline
Global Patents (CN925.1)
980 Great West Road
Brentford, Middlesex TW8 9GS / GB
[N/P]
Former [1995/03]Giddings, Peter John, Dr., et al
SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road
Brentford, Middlesex TW8 9BD / GB
Application number, filing date93911567.124.03.1993
[1995/03]
WO1993US02974
Priority number, dateGB1992000641324.03.1992         Original published format: GB 9206413
[1995/03]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9319081
Date:30.09.1993
Language:EN
[1993/24]
Type: A1 Application with search report 
No.:EP0633892
Date:18.01.1995
Language:EN
The application published by WIPO in one of the EPO official languages on 30.09.1993 takes the place of the publication of the European patent application.
[1995/03]
Type: B1 Patent specification 
No.:EP0633892
Date:26.05.1999
Language:EN
[1999/21]
Search report(s)International search report - published on:US30.09.1993
(Supplementary) European search report - dispatched on:EP03.04.1995
ClassificationIPC:C07J41/00, C07J75/00
[1995/03]
CPC:
C07J41/0066 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1995/03]
TitleGerman:N-T-BUTYL-ANDROST-3, 5-DIEN-17-beta-CARBOXAMID-3-CARBONSÄURE POLYMORPHA[1998/33]
English:N-T-BUTYL-ANDROST-3,5-DIENE-17-beta-CARBOXAMIDE-3-CARBOXYLIC ACID POLYMORPH A[1998/33]
French:POLYMORPHE A D'ACIDE N-T-BUTYL-ANDROST-3,5-DIENE-17-beta-CARBOXAMIDE-3-CARBOXYLIQUE[1998/33]
Former [1995/03]N-T-BUTYL-ANDROST-3, 5-DIEN-17-g(b)-CARBOXAMID-3-CARBONSÄURE POLYMORPHA
Former [1995/03]N-T-BUTYL-ANDROST-3,5-DIENE-17$g(b)-CARBOXAMIDE-3-CARBOXYLIC ACID POLYMORPH A
Former [1995/03]POLYMORPHE A D'ACIDE N-T-BUTYL-ANDROST-3,5-DIENE-17$g(b)-CARBOXAMIDE-3-CARBOXYLIQUE
Entry into regional phase27.09.1994National basic fee paid 
27.09.1994Search fee paid 
27.09.1994Designation fee(s) paid 
27.09.1994Examination fee paid 
Examination procedure21.10.1993Request for preliminary examination filed
International Preliminary Examining Authority: DE
27.09.1994Examination requested  [1995/03]
23.07.1997Despatch of a communication from the examining division (Time limit: M04)
20.11.1997Reply to a communication from the examining division
13.07.1998Despatch of communication of intention to grant (Approval: Yes)
23.10.1998Communication of intention to grant the patent
22.01.1999Fee for grant paid
22.01.1999Fee for publishing/printing paid
Opposition(s)29.02.2000No opposition filed within time limit [2000/20]
Fees paidRenewal fee
13.03.1995Renewal fee patent year 03
07.03.1996Renewal fee patent year 04
07.03.1997Renewal fee patent year 05
05.03.1998Renewal fee patent year 06
04.03.1999Renewal fee patent year 07
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Documents cited:Search[XD]EP0289327  (SMITHKLINE BECKMAN CORP [US]) [XD] 1,4,8* the whole document *
International search[YP]  - Endocrinology, 1992, LAMB et al., "Prostatic Involution in Rats Induced by a Novel 5 - Reductase Inhibitor, SK&F 105657: Role for Testosterone in the Androgenic Response", pp. 685-694, see 686.
 [YP]  - Proceedings of the National Academy of Sciences, 1992, HARRIS et al., "Identification and Selective Inhibition of an Isozyme of Steroid 5 - Reductase in Human Scalp", pp. 10787-10791, see p. 10789.
 [Y]  - Bioorganic Chemistry, 1989, METCALF et al., "Potent Inhibition of Human Steroid 5 - Reductase by 3-Androstene -3- Carboxylic Acids", pp. 372-376, see p. 374.
 [Y]  - Journal of Steroid Biochemistry, 1989, LEVY et al., "Interaction Between Rat Prostatic Steroid 5 - Reductase and 3-Carboxy-17B-Substituted Steroids: Novel Mechanism of Enzyme Inhibition", pp. 571-575, see 572-3.
 [Y]  - Biochemistry, 1990, LEVY et al., "Inhibition of Rat Liver Steroid 5 - Reductase by 3-Androstene-3- Carboxylic Acids: Mechanism of Enzyme Inhibitor Interaction", pp. 2815-2823, see p. 2817.
 [Y]  - Bioorganic Chemistry, 1991, LEVY et al., "3-Phosphinic Acid and 3-Phosphonic Acid Steroids as Inhibitors of Steroid 5 - Reductase: Species Comparison and Mechanistic Studies", pp. 245-260, see pp. 246, 254.
 [Y]  - Journal of Medicinal Chemistry, 1990, HOLT et al., "Inhibition of Steroid 5 - Reductase by Unsaturated 3-Carboxy Steroids", pp. 943-950, see p. 945.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.