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Extract from the Register of European Patents

EP About this file: EP0646170

EP0646170 - DIABETOGENE rad: A TYPE II DIABETES SPECIFIC GENE [Right-click to bookmark this link]
Former [1995/14]DIABETOGENE $i(rad): A TYPE II DIABETES SPECIFIC GENE
[2002/37]
StatusThe application is deemed to be withdrawn
Status updated on  16.05.2003
Database last updated on 03.09.2024
Most recent event   Tooltip16.05.2003Application deemed to be withdrawnpublished on 02.07.2003  [2003/27]
Applicant(s)For all designated states
JOSLIN DIABETES CENTER
One Joslin Place
Boston, MA 02215 / US
[1995/17]
Former [1995/14]For all designated states
THE JOSLIN DIABETES CENTER, INC.
One Joslin Place
Boston, MA 02215 / US
Inventor(s)01 / KAHN, C.Ronald
64 Valentine Park
West Newton, MA 02165 / US
02 / REYNET, Christine
80 Mount Vernon Street
Boston, MA 02115 / US
[1997/19]
Former [1995/14]01 / KAHN, C., Ronald
64 Valentine Park
West Newton, MA 02165 / US
02 / REYNET, Christine
80 Mount Vernon Street
Boston, MA 02115 / US
Representative(s)Ruffles, Graham Keith
Marks & Clerk LLP 62-68 Hills Road Cambridge
CB2 1LA / GB
[N/P]
Former [1995/14]Ruffles, Graham Keith
MARKS & CLERK, 57-60 Lincoln's Inn Fields
London WC2A 3LS / GB
Application number, filing date93915327.611.06.1993
[1995/14]
WO1993US05643
Priority number, dateUS1992090171019.06.1992         Original published format: US 901710
[1995/14]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9400558
Date:06.01.1994
Language:EN
[1994/02]
Type: A1 Application with search report 
No.:EP0646170
Date:05.04.1995
Language:EN
The application published by WIPO in one of the EPO official languages on 06.01.1994 takes the place of the publication of the European patent application.
[1995/14]
Search report(s)International search report - published on:US06.01.1994
(Supplementary) European search report - dispatched on:EP07.01.1997
ClassificationIPC:C12N15/12, C12N1/15, C12N1/21, C12N5/00, C12N5/10, C12N15/00, C12N15/10, C12N15/85, C12N15/90, C12Q1/68
[1997/06]
CPC:
C12N15/8509 (EP,US); A61P3/08 (EP); A61P3/10 (EP);
C07K14/47 (EP,US); C07K14/4713 (EP,US); C12N9/1051 (EP,US);
A01K2207/15 (EP,US); A01K2217/00 (EP,US); A01K2217/05 (EP,US);
A01K2217/075 (EP,US); A01K2227/10 (EP,US); A01K2227/105 (EP,US);
A01K2267/03 (EP,US); A01K2267/0306 (EP,US); A01K2267/0362 (EP,US);
A61K38/00 (EP,US); C07K2319/00 (EP,US) (-)
Former IPC [1995/14]C12N1/15, C12N1/21, C12N5/00, C12N5/10, C12N15/00, C12N15/10, C12N15/12, C12N15/85, C12N15/90, C12Q1/68, C12P21/02
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1995/14]
TitleGerman:DIABETOGEN rad: EIN TYPE II DIABETES SPEZIFISCHES GEN[2002/37]
English:DIABETOGENE rad: A TYPE II DIABETES SPECIFIC GENE[2002/37]
French:DIABETOGENE rad : UN GENE SPECIFIQUE AU DIABETE DE TYPE II[2002/37]
Former [1995/14]DIABETOGEN-i(rad): EIN TYPE II DIABETES SPEZIFISCHES GEN
Former [1995/14]DIABETOGENE $i(rad): A TYPE II DIABETES SPECIFIC GENE
Former [1995/14]$i(RAD) DIABETOGENE: UN GENE SPECIFIQUE AU DIABETE DE TYPE II
Entry into regional phase16.12.1994National basic fee paid 
16.12.1994Search fee paid 
16.12.1994Designation fee(s) paid 
16.12.1994Examination fee paid 
Examination procedure18.01.1994Request for preliminary examination filed
International Preliminary Examining Authority: US
16.12.1994Examination requested  [1995/14]
18.03.1999Despatch of a communication from the examining division (Time limit: M06)
20.09.1999Reply to a communication from the examining division
03.04.2000Despatch of a communication from the examining division (Time limit: M06)
04.10.2000Reply to a communication from the examining division
27.11.2000Despatch of a communication from the examining division (Time limit: M04)
29.03.2001Reply to a communication from the examining division
20.08.2001Despatch of a communication from the examining division (Time limit: M04)
26.11.2001Reply to a communication from the examining division
13.09.2002Communication of intention to grant the patent
03.01.2003Application deemed to be withdrawn, date of legal effect  [2003/27]
04.02.2003Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2003/27]
Fees paidRenewal fee
12.06.1995Renewal fee patent year 03
10.06.1996Renewal fee patent year 04
10.06.1997Renewal fee patent year 05
15.06.1998Renewal fee patent year 06
21.05.1999Renewal fee patent year 07
23.05.2000Renewal fee patent year 08
23.05.2001Renewal fee patent year 09
Penalty fee
Additional fee for renewal fee
30.06.200210   M06   Not yet paid
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Documents cited:Search[PX]  - REYNET C ET AL, "RAD: A novel member of the RAS-GTPase family over-expressed in muscle to type II diabetic humans.", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, XP002020949 [PX] 1 * abstract *
    [ ] - KEYSTONE SYMPOSIUM ON MOLECULAR MECHANISMS COMMON TO TYPES I AND II DIABETES, PARK CITY, UTAH, USA, JANUARY 14-21, 1993. JOURNAL OF CELLULAR BIOCHEMISTRY SUPPLEMENT 0 (18 PART A). 1994. 143. ISSN: 0733-1959
 [A]  - BRANDS, JOLANDA H. G. M. ET AL, "The primary structure of the.alpha. subunit of human elongation factor 1. Structural aspects of guanine nucleotide-binding sites", EUR. J. BIOCHEM. (1986), 155(1), 167-71 CODEN: EJBCAI;ISSN: 0014-2956, (1986), XP000612183 [A] 7-10 * the whole document *

DOI:   http://dx.doi.org/10.1111/j.1432-1033.1986.tb09472.x
 [A]  - UETSUKI, TAICHI ET AL, "Isolation and characterization of the human chromosomal gene for polypeptide chain elongation factor-1.alpha.", J. BIOL. CHEM. (1989), 264(10), 5791-8 CODEN: JBCHA3;ISSN: 0021-9258, (1989), XP002020945 [A] 7-10 * the whole document *
 [A]  - YOO, OOK JOON ET AL, "Cloning, expression and characterization of the human transcription elongation factor, TFIIS", NUCLEIC ACIDS RES. (1991), 19(5), 1073-9 CODEN: NARHAD;ISSN: 0305-1048, (1991), XP002020946 [A] 7-10 * the whole document *
 [A]  - GOMEZ-FOIX, ANNA M. ET AL, "Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism", J. BIOL. CHEM. (1992), 267(35), 25129-34 CODEN: JBCHA3;ISSN: 0021-9258, (1992), XP002020947 [A] 7-10 * the whole document *
 [A]  - CARLSON, M. ET AL, "Isolation and mapping of a polymorphic DNA sequence for human muscle glycogen phosphorylase (pMCMP1) on chromosome 11 [PYGM]", NUCLEIC ACIDS RES. (1988), 16(21), 10403 CODEN: NARHAD;ISSN: 0305-1048, (1988), XP002020948 [A] 7-10 * the whole document *
International search[YP]US5179017  (AXEL RICHARD [US], et al)
 [Y]  - Proceedings of the National Academy of Sciences, Volume 88, issued June 1991, L. MOSTHAF et al., "Altered Expression of Insulin Receptor Types A and B in the Skeletal Muscle of Non-Insulin-Dependent Diabetes Mellitus Patients", pages 4728-4730, especially page 4729.
 [Y]  - Science, Volume 240, issued 10 June 1988, R. JAENISCH, "Transgenic Animals", pages 1468-1474, especially pages 1470, 1471.
 [Y]  - Methods in Enzymology, Volume 152, issued 1987, A.R. SHATZMAN et al., "Expression, Identification, and Characterization of Recombinant Gene Products in Escherichia coli", pages 661-673, especially page 661.
 [Y]  - Molecular and Cellular Biology, Volume 10, No. 6, issued June 1990, B.F. SMITH et al., "Genes Transferred by Retroviral Vectors into Normal and Mutant Myoblasts in Primary Cultures are Expressed in Myotubes", pages 3268-3271, see entire document.
 [Y]  - J. SAMBROOK, E.F. FRITSCH, and T. MANIATIS, "Molecular Cloning, A Laboratory Manual", published 1989 by Cold Spring Harbor Laboratory Press (Cold Spring Harbor, NY), pages 10.38-10.50, see entire document.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.