EP0646170 - DIABETOGENE rad: A TYPE II DIABETES SPECIFIC GENE [Right-click to bookmark this link] | |||
Former [1995/14] | DIABETOGENE $i(rad): A TYPE II DIABETES SPECIFIC GENE | ||
[2002/37] | Status | The application is deemed to be withdrawn Status updated on 16.05.2003 Database last updated on 03.09.2024 | Most recent event Tooltip | 16.05.2003 | Application deemed to be withdrawn | published on 02.07.2003 [2003/27] | Applicant(s) | For all designated states JOSLIN DIABETES CENTER One Joslin Place Boston, MA 02215 / US | [1995/17] |
Former [1995/14] | For all designated states THE JOSLIN DIABETES CENTER, INC. One Joslin Place Boston, MA 02215 / US | Inventor(s) | 01 /
KAHN, C.Ronald 64 Valentine Park West Newton, MA 02165 / US | 02 /
REYNET, Christine 80 Mount Vernon Street Boston, MA 02115 / US | [1997/19] |
Former [1995/14] | 01 /
KAHN, C., Ronald 64 Valentine Park West Newton, MA 02165 / US | ||
02 /
REYNET, Christine 80 Mount Vernon Street Boston, MA 02115 / US | Representative(s) | Ruffles, Graham Keith Marks & Clerk LLP 62-68 Hills Road Cambridge CB2 1LA / GB | [N/P] |
Former [1995/14] | Ruffles, Graham Keith MARKS & CLERK, 57-60 Lincoln's Inn Fields London WC2A 3LS / GB | Application number, filing date | 93915327.6 | 11.06.1993 | [1995/14] | WO1993US05643 | Priority number, date | US19920901710 | 19.06.1992 Original published format: US 901710 | [1995/14] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO9400558 | Date: | 06.01.1994 | Language: | EN | [1994/02] | Type: | A1 Application with search report | No.: | EP0646170 | Date: | 05.04.1995 | Language: | EN | The application published by WIPO in one of the EPO official languages on 06.01.1994 takes the place of the publication of the European patent application. | [1995/14] | Search report(s) | International search report - published on: | US | 06.01.1994 | (Supplementary) European search report - dispatched on: | EP | 07.01.1997 | Classification | IPC: | C12N15/12, C12N1/15, C12N1/21, C12N5/00, C12N5/10, C12N15/00, C12N15/10, C12N15/85, C12N15/90, C12Q1/68 | [1997/06] | CPC: |
C12N15/8509 (EP,US);
A61P3/08 (EP);
A61P3/10 (EP);
C07K14/47 (EP,US);
C07K14/4713 (EP,US);
C12N9/1051 (EP,US);
A01K2207/15 (EP,US);
A01K2217/00 (EP,US);
A01K2217/05 (EP,US);
A01K2217/075 (EP,US);
A01K2227/10 (EP,US);
A01K2227/105 (EP,US);
A01K2267/03 (EP,US);
A01K2267/0306 (EP,US);
A01K2267/0362 (EP,US);
|
Former IPC [1995/14] | C12N1/15, C12N1/21, C12N5/00, C12N5/10, C12N15/00, C12N15/10, C12N15/12, C12N15/85, C12N15/90, C12Q1/68, C12P21/02 | Designated contracting states | AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1995/14] | Title | German: | DIABETOGEN rad: EIN TYPE II DIABETES SPEZIFISCHES GEN | [2002/37] | English: | DIABETOGENE rad: A TYPE II DIABETES SPECIFIC GENE | [2002/37] | French: | DIABETOGENE rad : UN GENE SPECIFIQUE AU DIABETE DE TYPE II | [2002/37] |
Former [1995/14] | DIABETOGEN-i(rad): EIN TYPE II DIABETES SPEZIFISCHES GEN | ||
Former [1995/14] | DIABETOGENE $i(rad): A TYPE II DIABETES SPECIFIC GENE | ||
Former [1995/14] | $i(RAD) DIABETOGENE: UN GENE SPECIFIQUE AU DIABETE DE TYPE II | Entry into regional phase | 16.12.1994 | National basic fee paid | 16.12.1994 | Search fee paid | 16.12.1994 | Designation fee(s) paid | 16.12.1994 | Examination fee paid | Examination procedure | 18.01.1994 | Request for preliminary examination filed International Preliminary Examining Authority: US | 16.12.1994 | Examination requested [1995/14] | 18.03.1999 | Despatch of a communication from the examining division (Time limit: M06) | 20.09.1999 | Reply to a communication from the examining division | 03.04.2000 | Despatch of a communication from the examining division (Time limit: M06) | 04.10.2000 | Reply to a communication from the examining division | 27.11.2000 | Despatch of a communication from the examining division (Time limit: M04) | 29.03.2001 | Reply to a communication from the examining division | 20.08.2001 | Despatch of a communication from the examining division (Time limit: M04) | 26.11.2001 | Reply to a communication from the examining division | 13.09.2002 | Communication of intention to grant the patent | 03.01.2003 | Application deemed to be withdrawn, date of legal effect [2003/27] | 04.02.2003 | Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2003/27] | Fees paid | Renewal fee | 12.06.1995 | Renewal fee patent year 03 | 10.06.1996 | Renewal fee patent year 04 | 10.06.1997 | Renewal fee patent year 05 | 15.06.1998 | Renewal fee patent year 06 | 21.05.1999 | Renewal fee patent year 07 | 23.05.2000 | Renewal fee patent year 08 | 23.05.2001 | Renewal fee patent year 09 | Penalty fee | Additional fee for renewal fee | 30.06.2002 | 10   M06   Not yet paid |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [PX] - REYNET C ET AL, "RAD: A novel member of the RAS-GTPase family over-expressed in muscle to type II diabetic humans.", BIOSIS, BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US, XP002020949 [PX] 1 * abstract * | [ ] - KEYSTONE SYMPOSIUM ON MOLECULAR MECHANISMS COMMON TO TYPES I AND II DIABETES, PARK CITY, UTAH, USA, JANUARY 14-21, 1993. JOURNAL OF CELLULAR BIOCHEMISTRY SUPPLEMENT 0 (18 PART A). 1994. 143. ISSN: 0733-1959 | [A] - BRANDS, JOLANDA H. G. M. ET AL, "The primary structure of the.alpha. subunit of human elongation factor 1. Structural aspects of guanine nucleotide-binding sites", EUR. J. BIOCHEM. (1986), 155(1), 167-71 CODEN: EJBCAI;ISSN: 0014-2956, (1986), XP000612183 [A] 7-10 * the whole document * DOI: http://dx.doi.org/10.1111/j.1432-1033.1986.tb09472.x | [A] - UETSUKI, TAICHI ET AL, "Isolation and characterization of the human chromosomal gene for polypeptide chain elongation factor-1.alpha.", J. BIOL. CHEM. (1989), 264(10), 5791-8 CODEN: JBCHA3;ISSN: 0021-9258, (1989), XP002020945 [A] 7-10 * the whole document * | [A] - YOO, OOK JOON ET AL, "Cloning, expression and characterization of the human transcription elongation factor, TFIIS", NUCLEIC ACIDS RES. (1991), 19(5), 1073-9 CODEN: NARHAD;ISSN: 0305-1048, (1991), XP002020946 [A] 7-10 * the whole document * | [A] - GOMEZ-FOIX, ANNA M. ET AL, "Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism", J. BIOL. CHEM. (1992), 267(35), 25129-34 CODEN: JBCHA3;ISSN: 0021-9258, (1992), XP002020947 [A] 7-10 * the whole document * | [A] - CARLSON, M. ET AL, "Isolation and mapping of a polymorphic DNA sequence for human muscle glycogen phosphorylase (pMCMP1) on chromosome 11 [PYGM]", NUCLEIC ACIDS RES. (1988), 16(21), 10403 CODEN: NARHAD;ISSN: 0305-1048, (1988), XP002020948 [A] 7-10 * the whole document * | International search | [YP]US5179017 (AXEL RICHARD [US], et al) | [Y] - Proceedings of the National Academy of Sciences, Volume 88, issued June 1991, L. MOSTHAF et al., "Altered Expression of Insulin Receptor Types A and B in the Skeletal Muscle of Non-Insulin-Dependent Diabetes Mellitus Patients", pages 4728-4730, especially page 4729. | [Y] - Science, Volume 240, issued 10 June 1988, R. JAENISCH, "Transgenic Animals", pages 1468-1474, especially pages 1470, 1471. | [Y] - Methods in Enzymology, Volume 152, issued 1987, A.R. SHATZMAN et al., "Expression, Identification, and Characterization of Recombinant Gene Products in Escherichia coli", pages 661-673, especially page 661. | [Y] - Molecular and Cellular Biology, Volume 10, No. 6, issued June 1990, B.F. SMITH et al., "Genes Transferred by Retroviral Vectors into Normal and Mutant Myoblasts in Primary Cultures are Expressed in Myotubes", pages 3268-3271, see entire document. | [Y] - J. SAMBROOK, E.F. FRITSCH, and T. MANIATIS, "Molecular Cloning, A Laboratory Manual", published 1989 by Cold Spring Harbor Laboratory Press (Cold Spring Harbor, NY), pages 10.38-10.50, see entire document. |