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EP About this file: EP0746610

EP0746610 - MAMMALIAN CLONING BY EMBRYONIC STEM CELL (ESC) NUCLEAR TRANSPLANTATION AND ESC [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 03.12.1999 Database last updated on 15.06.2024
Most recent event Tooltip	03.12.1999	Application deemed to be withdrawn	published on 19.01.2000 [2000/03]
Applicant(s)	For all designated states OHIO UNIVERSITY 1 President Street Athens Ohio 45701-2979 / US
	For all designated states POLISH ACADEMY OF SCIENCES INSTITUTE OF GENETICS AND ANIMAL BREEDING Astrzebiec 05-551 Mrokow / PL
	[N/P]
Former [1996/50]	For all designated states OHIO UNIVERSITY 1 President Street Athens, Ohio 45701-2979 / US
	For all designated states POLISH ACADEMY OF SCIENCES INSTITUTE OF GENETICS AND ANIMAL BREEDING Astrzebiec 05-551 Mrokow / PL
Inventor(s)	01 / REED, Michael A. Edison Animal Biotechnology Center Ohio University Wilson Hall West Green Room102 Athens, OH 45701-2979 / US
	02 / WAGNER, Thomas Edward Edison AnimalBiotechnology Center Ohio University Wilson Hall West Green Room102 Athens, OH 45701-2979 / US
	03 / MODLINSKI, Jacek A. Institute of Genetics and Animal Breeding Ul. Okrezna 3 PL-Warsaw / PL
	[1996/50]
Representative(s)	Ritter, Stephen David Mathys & Squire LLP 120 Holborn London EC1N 2SQ / GB
	[N/P]
Former [1996/50]	Ritter, Stephen David Mathys & Squire 100 Grays Inn Road London WC1X 8AL / GB
Application number, filing date	93923115.5	22.09.1993
	[1996/50]
	WO1993US08878
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9508625
	Date:	30.03.1995
	Language:	EN
	[1995/14]
	Type:	A1 Application with search report
	No.:	EP0746610
	Date:	11.12.1996
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 30.03.1995 takes the place of the publication of the European patent application.
	[1996/50]
Search report(s)	International search report - published on:	US	30.03.1995
	(Supplementary) European search report - dispatched on:	EP	09.10.1997
Classification	IPC:	C12N15/00, C12N15/06, A01K67/027, C12N15/90	[1996/51]
	CPC:	A01K67/0275 (EP); C12N15/90 (EP); A01K2217/05 (EP)
	Former IPC [1996/50]	C12N15/00, C12N15/06
Designated contracting states	AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LI, NL, PT, SE [1996/50]
Title	German:	KLONIERUNG VON SÄUGETIEREN DURCH NUKLEÄRE TRANSPLANTATION EMBRYONALER STAMMZELLEN UND ESC	[1996/50]
	English:	MAMMALIAN CLONING BY EMBRYONIC STEM CELL (ESC) NUCLEAR TRANSPLANTATION AND ESC	[1996/50]
	French:	CLONAGE MAMMALIEN PAR TRANSPLANTATION NUCLEAIRE DE CELLULES SOUCHES EMBRYONNAIRES (CSE) ET CSE	[1996/50]
Entry into regional phase	17.04.1996	National basic fee paid
	17.04.1996	Search fee paid
	17.04.1996	Designation fee(s) paid
	17.04.1996	Examination fee paid
Examination procedure	24.04.1995	Request for preliminary examination filed
	17.04.1996	Examination requested [1996/50]
	01.04.1999	Application deemed to be withdrawn, date of legal effect [2000/03]
	16.08.1999	Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2000/03]
Fees paid	Renewal fee
	17.04.1996	Renewal fee patent year 03
	21.09.1996	Renewal fee patent year 04
	25.09.1997	Renewal fee patent year 05
	Penalty fee
	Additional fee for renewal fee
	30.09.1998	06 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[XY] - MODLINSKI, J.A. ET AL., "Developmental capacity of mouse embryonic stem cells and embryonic stem cell nuclei", ANIMAL SCIENCE PAPERS AND REPORTS, (19930101), vol. 11, no. 2, pages 135 - 140, XP000603974 [X] 1-3 * the whole document * [Y] 1-12
		[ ] - Meeting "Molecular Biology and Embryo Technology in Animal Breeding" September 27-30, 1992 Jastrzebiec & Popielno, Poland
		[Y] - SEAMARK, R.F., "Embryo multiplication- Present status of nuclear transfer and embryonic stem cell technology in livestock", MEDE FAC LANDBOUW UNIV GENT, (1992), vol. 57, no. 4 part b, pages 1837 - 1842, XP000603947 [Y] 1-12 * the whole document *
		[Y] - REED, M.A. ET AL., "Progress in establishing embryonic stem cells in cattle", ANIMAL SCIENCE PAPERS AND REPORTS, (19930101), vol. 11, no. 2, pages 141 - 146, XP000603973 [Y] 3,4,7,8,11,12 * the whole document *
		[ ] - Meeting: "Molecular Biology and Embryo Technology in Animal Breeding" September 27-30, 1992 Jastrzbiec & Popielno, Poland
		[AX] - FIRST, N.L. & PRATHER, R.C., "Genomic potential in mammals", DIFFERENTIATION, (199109), vol. 48, no. 1, pages 1 - 8, XP000607074 [A] 1 * the whole document * [X] 5
		[T] - SIMS, M. ET FIRST, N.L., "Production of calves by transfer of nuclei from cultured inner cell mass cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, WASHINGTON US, (19940921), vol. 91, no. 13, pages 6143 - 6147, XP000604993 [T] 1-12 * the whole document *
		[T] - FIRST, N.L. ET AL., "Systems for production of calves from cultured bovine embryonic cells", REPRODUCTION , FERTILITY AND DEVELOPMENT, (19940101), vol. 6, no. 5, pages 553 - 562, XP000603897 [T] 1-12 * the whole document * DOI: http://dx.doi.org/10.1071/RD9940553
	International search	[Y]US5057420 ;
		[Y]US4873191 ;
		[Y]US4619899 ;
		[Y]US5032407 ;
		[Y]US4806476 ;
		[Y]US4664097
		[Y] - DEVELOPMENT, Volume 110, issued 1990, J. NICHOLS et al., "Establishment of Germ-Line-Competent Embryonic Stem (ES) Cells Using Differentiation Inhibiting Activity", pages 1341-1348.
		[Y] - JOURNAL OF EMBRYOLOGY AND EXPERIMENTAL MORPHOLOGY, Volume 87, issued 1985, T.C. DOETSCHMAN et al., "The In Vitro Development of Blastocyst-Derived Embryonic Stem Cell Lines: Formation of Visceral Yolk Sac, Blood Islands and Myocardium", pages 27-45.
		[Y] - EXPERIMENTAL CELL RESEARCH, Volume 190, issued 1990, S. PEASE et al., "Formation of Germ-Line Chimeras from Embryonic Stem Cells Maintained with Recombinant Leukemia Inhibitory Factor", pages 209-211.
		[Y] - TRENDS IN GENETICS, Volume 5, Number 8, issued August 1989, J. ROSSANT et al., "Towards a Molecular Genetic Analysis of Mammalian Development", pages 277-283.
		[Y] - THE EMBO JOURNAL, Volume 9, Number 10, issued 1990, E.F. WAGNER, "On Transferring Genes into Stem Cells and Mice", pages 3025-3032.
		[Y] - SCIENCE, Volume 240, issued 10 June 1988, R. JAENISCH, "Transgenic Animals", pages 1468-1474.
		[Y] - BIOTECHNIQUES, Volume 5, Number 7, issued 1987, S.A. CAMPER, "Research Applications of Transgenic Mice", pages 638-650.
		[Y] - JOURNAL OF EMBRYOLOGY AND EXPERIMENTAL MORPHOLOGY, Volume 73, issued 1983, M.H. KAUFMAN et al., "Establishment of Pluripotential Cell Lines from Haploid Mouse Embryos", pages 249-261.
		[Y] - TRENDS IN GENETICS, Volume 2, issued January 1986, E.J. ROBERTSON, "Pluripotential Stem Cell Lines as a Route into the Mouse Germ Line", pages 9-13.
		[Y] - BIOTECHNOLOGY, Volume 6, Number 10, issued October 1988, J. VAN BRUNT, "Molecular Farming: Transgenic Animals as Bioreactors", pages 1149-1154.
		[Y] - JOURNAL OF CELL SCIENCE, SUPPLEMENT, Volume 10, issued 1988, J.K. HEATH et al., "Regulatory Factors of Embryonic Stem Cells", pages 257-266.
		[Y] - JOURNAL OF REPRODUCTION AND FERTILITY, Volume 93, issued 1991, T. KONO et al., "Development of Enucleated Mouse Oocytes Reconstituted with Embryonic Nuclei", pages 165-172.
		[Y] - NATURE, Volume 273, issued 08 June 1978, J.A. MODLINSKI, "Transfer of Embryonic Nuclei to Fertilised Mouse Eggs and Development of Tetraploid Blastocysts", pages 466-467.
		[Y] - NATURE, Volume 292, issued 23 July 1981, J.A. MODLINSKI et al., "The Fate of Inner Cell Mass and Trophectoderm Nuclei Transplanted to Fertilized Mouse Eggs", pages 342-343.
		[Y] - NATURE, Volume 320, issued 06 March 1986, S.M. WILLADSEN, "Nuclear Transplantation in Sheep Embryos", pages 63-65.
		[Y] - SCIENCE, Volume 220, issued 1983, J. MCGRATH et al., "Nuclear Transplantation in the Mouse Embryo by Microsurgery and Cell Fusion", pages 1300-1302.
		[Y] - SCIENCE, Volume 226, issued 14 December 1984, J. MCGRATH et al., "Inability of Mouse Blastomere Nuclei Transferred to Enucleated Zygotes to Support Development In Vitro", pages 1317-1319.
		[Y] - JOURNAL OF CELL SCIENCE, Volume 69, issued 1984, R. CZOLOWSKA et al., "Behavior of Thymocyte Nuclei in Non-Activated and Activated Mouse Oocytes", pages 19-34.
		[Y] - JOURNAL OF CELL SCIENCE, Volume 84, issued 1986, R. CZOLOWSKA et al., "Chromosome Condensation Activity in Ovulated Metaphase II Mouse Oocytes Assayed by Fusion with Interphase Blastomeres", pages 129-138.
		[Y] - CELL, Volume 23, issued January 1981, K. ILLMENSEE, "Nuclear Transplantation in Mus Musculus: Developmental Potential of Nuclei from Preimplantation Embryos", pages 9-18.
		[Y] - DEVELOPMENT, Volume 107, issued 1989, Y. TSUNODA et al., "Nuclear Transplantation of Male Primordia Germ Cells in the Mouse", pages 407-411.
		[Y] - DEVELOPMENT, Volume 101, issued 1987, S.K. HOWLETT et al., "Nuclear Cytoplasmic Interactions Following Nuclear Transplantation in Mouse Embryos", pages 915-923.
		[Y] - DEVELOPMENT, Volume 108, issued 1990, J.A. MODLINSKI et al., "Nuclear Transfer from Teratocarcinoma Cells into Mouse Oocytes and Eggs", pages 337-348.

The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.

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