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Extract from the Register of European Patents

EP About this file: EP0675904

EP0675904 - HUMAN NEUTRALIZING MONOCLONAL ANTIBODIES TO HUMAN IMMUNODEFICIENCY VIRUS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  09.01.2004
Database last updated on 12.07.2024
Most recent event   Tooltip26.11.2004Lapse of the patent in a contracting state
New state(s): MC		published on 12.01.2005  [2005/02]
Applicant(s)For all designated states
THE SCRIPPS RESEARCH INSTITUTE
10666 North Torrey Pines Road
La Jolla, CA 92037 / US
[1995/41]
Inventor(s)01 / BURTON, Dennis R.
6044 Beaumont Avenue
La Jolla, CA 92041 / US
02 / BARBAS, Carlos F.
7425 Charmant Drive, Apartment 2816
San Diego, CA 92122 / US
03 / LERNER, Richard A.
7750 East Roseland Drive
La Jolla, CA 92037 / US
[1995/41]
Representative(s)Fisher, Adrian John
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [1995/41]Fisher, Adrian John
CARPMAELS & RANSFORD 43 Bloomsbury Square
London WC1A 2RA / GB
Application number, filing date93923749.130.09.1993
[1995/41]
WO1993US09328
Priority number, dateUS1992095414830.09.1992         Original published format: US 954148
[1995/41]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9407922
Date:14.04.1994
Language:EN
[1994/09]
Type: A1 Application with search report 
No.:EP0675904
Date:11.10.1995
Language:EN
The application published by WIPO in one of the EPO official languages on 14.04.1994 takes the place of the publication of the European patent application.
[1995/41]
Type: B1 Patent specification 
No.:EP0675904
Date:05.03.2003
Language:EN
[2003/10]
Search report(s)International search report - published on:US14.04.1994
(Supplementary) European search report - dispatched on:EP09.07.1996
ClassificationIPC:C12N15/13, A61K39/395, G01N33/569
[2003/09]
CPC:
C07K16/1063 (EP); A61K49/16 (EP); A61K51/10 (EP);
A61P31/12 (EP); C07K16/40 (EP); A61K38/00 (EP);
C07K2317/55 (EP); C07K2319/035 (EP); C07K2319/40 (EP) (-)
Former IPC [1996/33]C12N15/13, C07K15/28, A61K39/395, A61K43/00, G01N33/569
Former IPC [1995/41]C07K15/28, A61K39/395, A61K43/00
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1995/41]
TitleGerman:HUMANER NEUTRALISIERENDER MONOKLONALER ANTIKÖRPER GEGEN DEN DIE IMMUNSCHWÄCHE BEIM MENSCHEN HERVORRINGENDEN VIRUS[2003/10]
English:HUMAN NEUTRALIZING MONOCLONAL ANTIBODIES TO HUMAN IMMUNODEFICIENCY VIRUS[1995/41]
French:ANTICORPS MONOCLONAUX NEUTRALISATEURS HUMAINS CONTRE LE VIRUS DE L'IMMUNODEFICIENCE HUMAINE[1995/41]
Former [1995/41]HUMANE NEUTRALISIERENDE MONOKLONALE ANTIKÖRPER GEGEN DEN DIE IMMUNSCHWÄCHE AUSLÖSENDEN VIRUS AUS MENSCH
Entry into regional phase03.04.1995National basic fee paid 
03.04.1995Search fee paid 
03.04.1995Designation fee(s) paid 
03.04.1995Examination fee paid 
Examination procedure20.04.1994Request for preliminary examination filed
International Preliminary Examining Authority: US
03.04.1995Examination requested  [1995/41]
05.05.1999Despatch of a communication from the examining division (Time limit: M04)
08.09.1999Reply to a communication from the examining division
20.03.2000Despatch of a communication from the examining division (Time limit: M06)
22.08.2000Reply to a communication from the examining division
28.06.2001Despatch of communication of intention to grant (Approval: Yes)
17.01.2002Communication of intention to grant the patent
04.06.2002Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time
05.08.2002Fee for grant paid
05.08.2002Fee for publishing/printing paid
Opposition(s)08.12.2003No opposition filed within time limit [2004/09]
Request for further processing for:05.08.2002Request for further processing filed
05.08.2002Full payment received (date of receipt of payment)
Request granted
12.12.2002Decision despatched
Fees paidRenewal fee
03.04.1995Renewal fee patent year 03
12.09.1996Renewal fee patent year 04
10.09.1997Renewal fee patent year 05
09.09.1998Renewal fee patent year 06
13.09.1999Renewal fee patent year 07
13.09.2000Renewal fee patent year 08
12.09.2001Renewal fee patent year 09
27.09.2002Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT05.03.2003
BE05.03.2003
CH05.03.2003
GR05.03.2003
LI05.03.2003
NL05.03.2003
DK05.06.2003
PT05.06.2003
SE05.06.2003
IE30.09.2003
LU30.09.2003
MC30.09.2003
[2005/02]
Former [2004/40]AT05.03.2003
BE05.03.2003
CH05.03.2003
GR05.03.2003
LI05.03.2003
NL05.03.2003
DK05.06.2003
PT05.06.2003
SE05.06.2003
IE30.09.2003
LU30.09.2003
Former [2004/39]AT05.03.2003
BE05.03.2003
CH05.03.2003
GR05.03.2003
LI05.03.2003
NL05.03.2003
DK05.06.2003
PT05.06.2003
SE05.06.2003
LU30.09.2003
Former [2004/23]AT05.03.2003
BE05.03.2003
CH05.03.2003
GR05.03.2003
LI05.03.2003
NL05.03.2003
DK05.06.2003
PT05.06.2003
SE05.06.2003
Former [2004/10]AT05.03.2003
BE05.03.2003
CH05.03.2003
GR05.03.2003
LI05.03.2003
NL05.03.2003
PT05.06.2003
SE05.06.2003
Former [2003/50]AT05.03.2003
CH05.03.2003
GR05.03.2003
LI05.03.2003
NL05.03.2003
PT05.06.2003
SE05.06.2003
Former [2003/47]AT05.03.2003
CH05.03.2003
GR05.03.2003
LI05.03.2003
NL05.03.2003
PT05.06.2003
Former [2003/46]CH05.03.2003
GR05.03.2003
LI05.03.2003
NL05.03.2003
PT05.06.2003
Former [2003/43]CH05.03.2003
LI05.03.2003
NL05.03.2003
PT05.06.2003
Former [2003/41]CH05.03.2003
LI05.03.2003
NL05.03.2003
Former [2003/40]CH05.03.2003
LI05.03.2003
Documents cited:Search[A]  - BUCHACHER A. ET AL., "Human Monoclonal Antibodies against gp41 and gp120 as Potential Agent for Passive Immunization", VACCINES 92: MOD. APPROACHES NEW VACCINES INCL. PREV. AIDS [ANNU. MEET.], 9TH (1992), 191-195. EDITOR(S): BROWN, FRED. PUBLISHER: COLD SPRING HARBOR LAB. PRESS, COLD SPRING HARBOR, N. Y., (1992), XP002006404 [A] 1-33 * the whole document *
 [A]  - ZEBEDEE S.L. ET AL., "Human combinatorial antibody libraries to hepatitis B", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, WASHINGTON US, (19920415), vol. 89, no. 8, pages 3175 - 3179, XP002006405 [A] 1-33 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.89.8.3175
 [PX]  - BARBAS C F III ET AL, "RECOMBINANT HUMAN FAB FRAGMENTS NEUTRALIZE HUMAN TYPE 1 IMMUNODEFICIENCY VIRUS IN-VITRO.", PROC NATL ACAD SCI U S A 89 (19). 1992. 9339-9343, XP002006406 [PX] 1-33 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.89.19.9339
International search[XY]  - Proceedings of the National Academy of Sciences, USA, Vol. 88, issued November 1991, BURTON et al., "A Large Array of Human Monoclonal Antibodies to Type 1 Human Immunodeficiency Virus from Combinatorial Libraries of Asymptomatic Seropositive Inidividuals", pages 10134-10137, see entire document and especially Figure 1.
 [Y]  - Journal of Virology, Vol. 65, No. 1, issued january 1991, HO et al., "Conformational Epitope on gp120 Important in CD4 Binding and Human Immunodeficiency Virus Type 1 Neutralization Identified by a Human Monoclonal Antibody", pages 489-493, see entire document.
 [Y]  - Proceedings of the National Academy of Sciences, USA, Vol. 88, issued April 1991, GORNY et al., "Production of Site-Selected Neutralizing Human Monoclonal Antibodies against the Third Variable Domain of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein", pages 3238-3242, see entire document.
 [Y]  - Journal of Immunology, Vol. 146, No. 12, issued 15 June 1991, POSNER et al., "An IgG Human Monoclonal Antibody that Reacts with HIV-1/gp120, Inhibits Virus Binding to Cells, and Neutralizes Infection", pages 4325-4332, see entire document.
 [Y]  - Research Virology, Vol. 142, issued 1991, TILLEY et al., "A Human Monoclonal Antibody Against CD4-Binding Site of HIV1 gp120 Exhibits Potent, Broadly Neutralizing Activity", pages 247-259, see entire document.
 [Y]  - AIDS Research and Human Retroviruses, Vol. 8, No. 6, issued June 1992, KARWOWSKA et al., "Production of Human Monoclonal Antibodies Specific for Conformational and Linear Non-V3 Epitopes of gp120", pages 1099-1106, see entire document.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.