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Extract from the Register of European Patents

EP About this file: EP0671923

EP0671923 - LIVER RESERVE CELLS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  22.02.2002
Database last updated on 19.10.2024
Most recent event   Tooltip22.02.2002No opposition filed within time limitpublished on 10.04.2002  [2002/15]
Applicant(s)For all designated states
ADVANCED TISSUE SCIENCES, INC.
10933 North Torrey Pines Road
La Jolla, CA 92037 / US
[1995/38]
Inventor(s)01 / NAUGHTON, Brian A.
10461 Quail Canyon Road
El Cajon, CA 92021 / US
02 / SIBANDA, Benson
2652 Sycamore Drive
Oceanside, CA 92056 / US
[1996/44]
Former [1995/38]01 / NAUGHTON, Brian, A.
10461 Quail Canyon Road
El Cajon, CA 92021 / US
02 / SIBANDA, Benson
2652 Sycamore Drive
Oceanside, CA 92056 / US
Representative(s)Bentz, Jean-Paul, et al
Cabinet Weinstein
56A Rue du Faubourg Saint-Honoré
75008 Paris / FR
[N/P]
Former [2001/03]Bentz, Jean-Paul, et al
Cabinet Weinstein, 56 A, rue du Faubourg Saint-Honoré
75008 Paris / FR
Former [1995/38]Durand, Yves Armand Louis
CABINET WEINSTEIN 20, Avenue de Friedland
F-75008 Paris / FR
Application number, filing date93923823.408.10.1993
[1995/38]
WO1993US09657
Priority number, dateUS1992095862109.10.1992         Original published format: US 958621
[1995/38]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9408598
Date:28.04.1994
Language:EN
[1994/10]
Type: A1 Application with search report 
No.:EP0671923
Date:20.09.1995
Language:EN
The application published by WIPO in one of the EPO official languages on 28.04.1994 takes the place of the publication of the European patent application.
[1995/38]
Type: B1 Patent specification 
No.:EP0671923
Date:18.04.2001
Language:EN
[2001/16]
Search report(s)International search report - published on:US28.04.1994
(Supplementary) European search report - dispatched on:EP08.07.1996
ClassificationIPC:A61K35/407, A61K45/00, A61K48/00, C12N5/00, C12N5/06, C12N5/08, C12N5/16, C12N5/22
[1995/38]
CPC:
A61K48/00 (EP,US); C12N5/16 (KR); A61K35/407 (EP,US);
A61P1/16 (EP); C12N5/0672 (EP,US); A61K35/12 (EP,US)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1995/38]
TitleGerman:LEBERRESERVEZELLEN[1995/38]
English:LIVER RESERVE CELLS[1995/38]
French:CELLULES HEPATIQUES DE RESERVE[1995/38]
Entry into regional phase09.05.1995National basic fee paid 
09.05.1995Search fee paid 
09.05.1995Designation fee(s) paid 
09.05.1995Examination fee paid 
Examination procedure03.05.1994Request for preliminary examination filed
International Preliminary Examining Authority: US
09.05.1995Examination requested  [1995/38]
02.07.1998Despatch of a communication from the examining division (Time limit: M06)
08.12.1998Reply to a communication from the examining division
30.12.1998Despatch of a communication from the examining division (Time limit: M04)
22.04.1999Reply to a communication from the examining division
24.07.2000Despatch of communication of intention to grant (Approval: Yes)
20.10.2000Communication of intention to grant the patent
24.01.2001Fee for grant paid
24.01.2001Fee for publishing/printing paid
Opposition(s)19.01.2002No opposition filed within time limit [2002/15]
Fees paidRenewal fee
21.10.1995Renewal fee patent year 03
18.10.1996Renewal fee patent year 04
29.08.1997Renewal fee patent year 05
01.08.1998Renewal fee patent year 06
20.09.1999Renewal fee patent year 07
15.09.2000Renewal fee patent year 08
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipBE18.04.2001
[2002/12]
Documents cited:Search[E]WO9402601  (UNIV PENNSYLVANIA [US], et al) [E] 15-18* page 5, paragraph 2 - page 11, paragraph 2 *;
 [XA]  - SIGAL ET AL, "THE LIVER AS A STEM CELL AND LINEAGE SYSTEM", AMERICAN JOURNAL OF PHYSIOLOGY, (199208), vol. 263, no. 2, pages G139 - G148, XP000572600 [X] 15-18 * the whole document * [A]
 [PA]  - HARRISON ET AL, "PRIMITIVE HEMOPOIETIC STEM CELLS:DIRECT ASSAY OF MOST PRODUCTIVE POPULATIONS BY COMPETITIVE REPOPULATION WITH SIMPLE BINOMIAL,CORRELATION AND COVARIANCE CALCULATIONS", EXPERIMENTAL HEMATOLOGY, (199302), vol. 21, pages 206 - 219, XP000568703
 [PA]  - HUANG ET AL, "FORMATION OF HAEMATOPOIETIC MICROENVIROMENT AND HAEMATOPOIETIC STEM CELLS FROM SINGLE HUMAN BONE MARROW STEM CELLS", NATURE, (199212), vol. 360, pages 745 - 749, XP002005282

DOI:   http://dx.doi.org/10.1038/360745a0
 [A]  - CHOWDHURY ET AL, "LONG-TERM IMPROVEMENT OF HYPERCHOLESTEROLEMIA AFTER EX VIVO GENE THERAPY IN LDLR-DEFICIENT RABBITS", SCIENCE, (19911220), vol. 254, pages 1802 - 1805, XP002005283

DOI:   http://dx.doi.org/10.1126/science.1722351
 [A]  - LAPIDOT ET AL, "CYTOKINE STIMULATION OF MULTILINEAGE HEMATOPOIESIS FROM IMMATURE HUMAN CELLS ENGRAFTED IN SCID MICE", SCIENCE, (19920228), vol. 255, pages 1137 - 1141, XP002005284

DOI:   http://dx.doi.org/10.1126/science.1372131
International search[Y]  - Hepatology, Volume 6, No. 5, issued 1986, J.J. GUMUCIO et al., "The Isolation of Functionally Heterogeneous Hepatocytes of the Proximal and Distal Half of the Liver Acinus in the Rat", pages 932-944, especially pages 934 and 938-939.
 [Y]  - Cancer Research, Volume 45, issued November 1985, C.J. PETROPOULOS et al., "Cell Lineages in Liver Carcinogenesis: Possible Clues from Studies of the Distribution of Alpha-Fetoprotein RNA Sequences in Cell Populations Isolated from Normal, Regenerating, and Preneoplastic Rat Livers", pages 5762-5768, especially pages
 [Y]  - Cancer Research, Volume 50, issued 01 July 1990, S. SELL, "Is There a Liver Stem Cell?", pages 3811-3815, especially page 3813.
 [Y]  - Science, Volume 233, issued 12 September 1986, A. DEMITRIOU, "Replacement of Liver Function in Rats by Transplantation of Microcarrier-Attached Hepatocytes", pages 1190-1192, especially page 1190.
 [Y]  - Proceedings of the National Academy of Sciences, Volume 87, issued November 1990, J.M. WILSON et al., "Temporary Amelioration of Hyperlipidemia in Low Density Lipoprotein Receptor-Deficient Rabbits Transplanted with Genetically Modified Hepatocytes", pages 8437-8441, especially page 8437.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.