EP0671923 - LIVER RESERVE CELLS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 22.02.2002 Database last updated on 19.10.2024 | Most recent event Tooltip | 22.02.2002 | No opposition filed within time limit | published on 10.04.2002 [2002/15] | Applicant(s) | For all designated states ADVANCED TISSUE SCIENCES, INC. 10933 North Torrey Pines Road La Jolla, CA 92037 / US | [1995/38] | Inventor(s) | 01 /
NAUGHTON, Brian A. 10461 Quail Canyon Road El Cajon, CA 92021 / US | 02 /
SIBANDA, Benson 2652 Sycamore Drive Oceanside, CA 92056 / US | [1996/44] |
Former [1995/38] | 01 /
NAUGHTON, Brian, A. 10461 Quail Canyon Road El Cajon, CA 92021 / US | ||
02 /
SIBANDA, Benson 2652 Sycamore Drive Oceanside, CA 92056 / US | Representative(s) | Bentz, Jean-Paul, et al Cabinet Weinstein 56A Rue du Faubourg Saint-Honoré 75008 Paris / FR | [N/P] |
Former [2001/03] | Bentz, Jean-Paul, et al Cabinet Weinstein, 56 A, rue du Faubourg Saint-Honoré 75008 Paris / FR | ||
Former [1995/38] | Durand, Yves Armand Louis CABINET WEINSTEIN 20, Avenue de Friedland F-75008 Paris / FR | Application number, filing date | 93923823.4 | 08.10.1993 | [1995/38] | WO1993US09657 | Priority number, date | US19920958621 | 09.10.1992 Original published format: US 958621 | [1995/38] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO9408598 | Date: | 28.04.1994 | Language: | EN | [1994/10] | Type: | A1 Application with search report | No.: | EP0671923 | Date: | 20.09.1995 | Language: | EN | The application published by WIPO in one of the EPO official languages on 28.04.1994 takes the place of the publication of the European patent application. | [1995/38] | Type: | B1 Patent specification | No.: | EP0671923 | Date: | 18.04.2001 | Language: | EN | [2001/16] | Search report(s) | International search report - published on: | US | 28.04.1994 | (Supplementary) European search report - dispatched on: | EP | 08.07.1996 | Classification | IPC: | A61K35/407, A61K45/00, A61K48/00, C12N5/00, C12N5/06, C12N5/08, C12N5/16, C12N5/22 | [1995/38] | CPC: |
A61K48/00 (EP,US);
C12N5/16 (KR);
A61K35/407 (EP,US);
A61P1/16 (EP);
C12N5/0672 (EP,US);
A61K35/12 (EP,US)
| Designated contracting states | AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1995/38] | Title | German: | LEBERRESERVEZELLEN | [1995/38] | English: | LIVER RESERVE CELLS | [1995/38] | French: | CELLULES HEPATIQUES DE RESERVE | [1995/38] | Entry into regional phase | 09.05.1995 | National basic fee paid | 09.05.1995 | Search fee paid | 09.05.1995 | Designation fee(s) paid | 09.05.1995 | Examination fee paid | Examination procedure | 03.05.1994 | Request for preliminary examination filed International Preliminary Examining Authority: US | 09.05.1995 | Examination requested [1995/38] | 02.07.1998 | Despatch of a communication from the examining division (Time limit: M06) | 08.12.1998 | Reply to a communication from the examining division | 30.12.1998 | Despatch of a communication from the examining division (Time limit: M04) | 22.04.1999 | Reply to a communication from the examining division | 24.07.2000 | Despatch of communication of intention to grant (Approval: Yes) | 20.10.2000 | Communication of intention to grant the patent | 24.01.2001 | Fee for grant paid | 24.01.2001 | Fee for publishing/printing paid | Opposition(s) | 19.01.2002 | No opposition filed within time limit [2002/15] | Fees paid | Renewal fee | 21.10.1995 | Renewal fee patent year 03 | 18.10.1996 | Renewal fee patent year 04 | 29.08.1997 | Renewal fee patent year 05 | 01.08.1998 | Renewal fee patent year 06 | 20.09.1999 | Renewal fee patent year 07 | 15.09.2000 | Renewal fee patent year 08 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | BE | 18.04.2001 | [2002/12] | Documents cited: | Search | [E]WO9402601 (UNIV PENNSYLVANIA [US], et al) [E] 15-18* page 5, paragraph 2 - page 11, paragraph 2 *; | [XA] - SIGAL ET AL, "THE LIVER AS A STEM CELL AND LINEAGE SYSTEM", AMERICAN JOURNAL OF PHYSIOLOGY, (199208), vol. 263, no. 2, pages G139 - G148, XP000572600 [X] 15-18 * the whole document * [A] | [PA] - HARRISON ET AL, "PRIMITIVE HEMOPOIETIC STEM CELLS:DIRECT ASSAY OF MOST PRODUCTIVE POPULATIONS BY COMPETITIVE REPOPULATION WITH SIMPLE BINOMIAL,CORRELATION AND COVARIANCE CALCULATIONS", EXPERIMENTAL HEMATOLOGY, (199302), vol. 21, pages 206 - 219, XP000568703 | [PA] - HUANG ET AL, "FORMATION OF HAEMATOPOIETIC MICROENVIROMENT AND HAEMATOPOIETIC STEM CELLS FROM SINGLE HUMAN BONE MARROW STEM CELLS", NATURE, (199212), vol. 360, pages 745 - 749, XP002005282 DOI: http://dx.doi.org/10.1038/360745a0 | [A] - CHOWDHURY ET AL, "LONG-TERM IMPROVEMENT OF HYPERCHOLESTEROLEMIA AFTER EX VIVO GENE THERAPY IN LDLR-DEFICIENT RABBITS", SCIENCE, (19911220), vol. 254, pages 1802 - 1805, XP002005283 DOI: http://dx.doi.org/10.1126/science.1722351 | [A] - LAPIDOT ET AL, "CYTOKINE STIMULATION OF MULTILINEAGE HEMATOPOIESIS FROM IMMATURE HUMAN CELLS ENGRAFTED IN SCID MICE", SCIENCE, (19920228), vol. 255, pages 1137 - 1141, XP002005284 DOI: http://dx.doi.org/10.1126/science.1372131 | International search | [Y] - Hepatology, Volume 6, No. 5, issued 1986, J.J. GUMUCIO et al., "The Isolation of Functionally Heterogeneous Hepatocytes of the Proximal and Distal Half of the Liver Acinus in the Rat", pages 932-944, especially pages 934 and 938-939. | [Y] - Cancer Research, Volume 45, issued November 1985, C.J. PETROPOULOS et al., "Cell Lineages in Liver Carcinogenesis: Possible Clues from Studies of the Distribution of Alpha-Fetoprotein RNA Sequences in Cell Populations Isolated from Normal, Regenerating, and Preneoplastic Rat Livers", pages 5762-5768, especially pages | [Y] - Cancer Research, Volume 50, issued 01 July 1990, S. SELL, "Is There a Liver Stem Cell?", pages 3811-3815, especially page 3813. | [Y] - Science, Volume 233, issued 12 September 1986, A. DEMITRIOU, "Replacement of Liver Function in Rats by Transplantation of Microcarrier-Attached Hepatocytes", pages 1190-1192, especially page 1190. | [Y] - Proceedings of the National Academy of Sciences, Volume 87, issued November 1990, J.M. WILSON et al., "Temporary Amelioration of Hyperlipidemia in Low Density Lipoprotein Receptor-Deficient Rabbits Transplanted with Genetically Modified Hepatocytes", pages 8437-8441, especially page 8437. |