EP0610046 - Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispesific fusion proteins in a mammalian cell [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 27.10.2006 Database last updated on 29.07.2024 | Most recent event Tooltip | 05.09.2008 | Change - representative | published on 08.10.2008 [2008/41] | Applicant(s) | For all designated states Bristol-Myers Squibb Company Route 206 and Province Line Road Princeton, NJ 08543 / US | [N/P] |
Former [1994/32] | For all designated states Bristol-Myers Squibb Company 345 Park Avenue New York, N.Y. 10154 / US | Inventor(s) | 01 /
Ledbetter, Jeffrey A. 306 NW 113th Place Seattle, WA 98177 / US | 02 /
Gilliland, Lisa K. 3007 NE 88th Street Seattle, WA 98119 / US | 03 /
Hayden, Martha S. 9896-1 Mercy Road San Diego, CA 92129 / US | 04 /
Linsley, Peter S. 2430 9th Avenue W. Seattle, WA 98119 / US | 05 /
Bajorath, Jurgen 928 137th Street SW Everett, WA 98204 / US | 06 /
Fell, Perry H. 741 218th Place NE Redmond, WA 98053 / US | [1994/32] | Representative(s) | Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB | [N/P] |
Former [2008/41] | Carpmaels & Ransford One Southampton Row London WC1B 5HA / GB | ||
Former [2003/17] | Carpmaels & Ransford 43 Bloomsbury Square London WC1A 2RA / GB | ||
Former [1994/32] | Jones, Alan John, et al CARPMAELS & RANSFORD 43 Bloomsbury Square London, WC1A 2RA / GB | Application number, filing date | 94300692.4 | 31.01.1994 | [1994/32] | Priority number, date | US19930013420 | 01.02.1993 Original published format: US 13420 | US19930121054 | 13.09.1993 Original published format: US 121054 | [1994/32] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP0610046 | Date: | 10.08.1994 | Language: | EN | [1994/32] | Type: | A3 Search report | No.: | EP0610046 | Date: | 24.04.1996 | [1996/17] | Type: | B1 Patent specification | No.: | EP0610046 | Date: | 21.12.2005 | Language: | EN | [2005/51] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 08.03.1996 | Classification | IPC: | C12N15/62, C12N5/10, C12P21/00, C07K19/00, A61K39/395, G01N33/563 | [2005/51] | CPC: |
C07K14/005 (EP,US);
C07K14/70521 (EP,US);
C07K14/7155 (EP,US);
C07K16/00 (EP,US);
C07K16/2809 (EP,US);
C07K16/2818 (EP,US);
C07K16/2827 (EP,US);
C07K16/30 (EP,US);
C07K16/468 (EP,US);
C12N15/62 (EP,US);
G01N33/563 (EP,US);
G01N33/56972 (EP,US);
G01N33/57492 (EP,US);
A61K2039/505 (EP,US);
A61K38/00 (EP,US);
C07K2317/31 (EP,US);
C07K2317/34 (EP,US);
C07K2317/622 (EP,US);
C07K2317/732 (EP,US);
C07K2317/734 (EP,US);
C07K2317/74 (EP,US);
C07K2319/00 (EP,US);
C07K2319/02 (EP,US);
C07K2319/30 (EP,US);
|
Former IPC [1994/32] | C12N15/62, C12N15/13, C12N5/10, C12P21/08, C07K15/00, A61K39/395, G01N33/563 | Designated contracting states | AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1994/32] | Title | German: | Expressionsvektoren die für bispezifische Proteine kodieren, und Verfahren zur Herstellung von biologisch-aktiven bispezifischen Fusionsproteine in Zellen von Säugertieren | [1994/32] | English: | Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispesific fusion proteins in a mammalian cell | [1994/32] | French: | Vecteurs d'expression codant pour des proteins de fusion bispécifiques et méthodes pour la production de ces protéins dans des cellules de mammifèrres | [1994/32] | Biological material | This application mentions deposited biological material, check the file for details | Examination procedure | 10.07.1996 | Examination requested [1996/36] | 06.02.2002 | Despatch of a communication from the examining division (Time limit: M06) | 14.08.2002 | Reply to a communication from the examining division | 06.09.2002 | Despatch of a communication from the examining division (Time limit: M06) | 17.03.2003 | Reply to a communication from the examining division | 09.04.2003 | Despatch of a communication from the examining division (Time limit: M06) | 20.10.2003 | Reply to a communication from the examining division | 21.05.2004 | Despatch of a communication from the examining division (Time limit: M04) | 21.09.2004 | Reply to a communication from the examining division | 19.01.2005 | Communication of intention to grant the patent | 07.07.2005 | Fee for grant paid | 07.07.2005 | Fee for publishing/printing paid | Divisional application(s) | EP05077801.8 / EP1746162 | Opposition(s) | 22.09.2006 | No opposition filed within time limit [2006/48] | Fees paid | Renewal fee | 26.01.1996 | Renewal fee patent year 03 | 08.01.1997 | Renewal fee patent year 04 | 08.01.1998 | Renewal fee patent year 05 | 11.01.1999 | Renewal fee patent year 06 | 10.01.2000 | Renewal fee patent year 07 | 11.01.2001 | Renewal fee patent year 08 | 14.01.2002 | Renewal fee patent year 09 | 14.01.2003 | Renewal fee patent year 10 | 14.01.2004 | Renewal fee patent year 11 | 12.01.2005 | Renewal fee patent year 12 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X]WO8801649 (GENEX CORP [US]) [X] 1 * Claims *; | [XY]WO8809344 (CREATIVE BIOMOLECULES INC [US]) [X] 1,2,4-6,11-13,25-30 * the whole document * [Y] 7-10,14-17; | [Y]EP0439095 (BRISTOL MYERS SQUIBB CO [US]) [Y] 8,15 * Claims *; | [Y]WO9200092 (BRISTOL MYERS SQUIBB CO [US]) [Y] 10,17 * claims 1,4,6,7 *; | [X]EP0506124 (TANOX BIOSYSTEMS INC [US]) [X] 1 * the whole document *; | [Y]WO9300431 (BRISTOL MYERS SQUIBB CO [US]) [Y] 9,16 * claims 3-26 *; | [XY] - HUSTON, J.S. ET AL.;, "Molecular Design and Modeling : Concepts and applications -Part B : antibodies and antigens, nucleic acids, polysaccharides and drugs.", METHODS IN ENZYMOLOGY;, vol. 203, pages 47 - 89, XP002573811 [X] 1-6,11-13,25-30 * [3] Protein engineering of single-chain Fv analogs and fusion proteins * * Paragraph "Linker chemistry" * [Y] 7-10,14-17 | [Y] - KOSTELNY, S.A.; COLE, M.S. AND TSO, J.Y., "Formation of a bispecific antibody by the use of leucine zippers", JOURNAL OF IMMUNOLOGY, BALTIMORE US, (19920301), vol. 148, no. 5, pages 1547 - 1553 [Y] 7,14 * the whole document * | [A] - 1992;NOLAN, O.; O'KENNEDY, R., "Bifunctional antibodies and their potential clinical applications", INTERNATIONAL JOURNAL OF CLINICAL & LABORATORY RESEARCH, vol. 22, pages 21 - 27, XP009023533 [A] 1-30 * the whole document * |