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Extract from the Register of European Patents

EP About this file: EP0688220

EP0688220 - USE OF DHEA AND DERIVATIVES THEREOF FOR THE MANUFACTURE OF A MEDICAMENT FOR PREVENTING PROGRESSIVE TISSUE NECROSIS, REPERFUSION INJURY, BACTERIAL TRANSLOCATION AND ADULT RESPIRATORY DISTRESS SYNDROME [Right-click to bookmark this link]
Former [1995/52]METHODS FOR PREVENTING PROGRESSIVE TISSUE NECROSIS, REPERFUSION INJURY, BACTERIAL TRANSLOCATION AND ADULT RESPIRATORY DISTRESS SYNDROME
[2002/21]
StatusNo opposition filed within time limit
Status updated on  30.09.2005
Database last updated on 24.07.2024
Most recent event   Tooltip28.12.2007Lapse of the patent in a contracting state
New state(s): PT		published on 30.01.2008  [2008/05]
Applicant(s)For all designated states
University of Utah Research Foundation
615 Arapeen Drive
Suite 110
Salt Lake City, UT 84108 / US
[N/P]
Former [2003/01]For all designated states
UNIVERSITY OF UTAH RESEARCH FOUNDATION
615 Arapeen Drive, Suite 110
Salt Lake City, UT 84108 / US
Former [2002/50]For all designated states
The University of Utah Research Foundation
615 Arapeen Drive, Suite 110
Salt Lake City, Utah 84108 / US
Former [1995/52]For all designated states
UNIVERSITY OF UTAH RESEARCH FOUNDATION
421 Wakara Way, Suite 170
Salt Lake City, Utah 84108 / US
Inventor(s)01 / DAYNES, Raymond, A.
8433 Cottonwood Trail
Park City, UT 84060 / US
02 / ARANEO, Barbara, A.
2434 Kentucky Avenue
Salt Lake City, UT 84117 / US
[1995/52]
Representative(s)Rambelli, Paolo, et al
Jacobacci & Partners S.p.A.
Corso Emilia 8
10152 Torino / IT
[N/P]
Former [1995/52]Rambelli, Paolo, et al
c/o JACOBACCI & PERANI S.p.A. Corso Regio Parco, 27
I-10152 Torino / IT
Application number, filing date94911522.408.03.1994
[1995/52]
WO1994US02558
Priority number, dateUS1993002942209.03.1993         Original published format: US 29422
[1995/52]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9420111
Date:15.09.1994
Language:EN
[1994/21]
Type: A1 Application with search report 
No.:EP0688220
Date:27.12.1995
Language:EN
The application published by WIPO in one of the EPO official languages on 15.09.1994 takes the place of the publication of the European patent application.
[1995/52]
Type: B1 Patent specification 
No.:EP0688220
Date:24.11.2004
Language:EN
[2004/48]
Search report(s)International search report - published on:US15.09.1994
(Supplementary) European search report - dispatched on:EP13.02.1998
ClassificationIPC:A61K31/56, A61K31/5685, A61P11/00, A61P9/10, A61P43/00
[2002/21]
CPC:
A61K31/569 (EP,US); A61K31/56 (KR); A61K31/565 (EP,US);
A61K31/566 (EP,US); A61K31/568 (EP,US); A61K31/57 (EP,US);
A61K31/573 (EP,US); A61K31/575 (EP,US); A61K31/58 (EP,US);
A61P11/00 (EP); A61P43/00 (EP); A61P9/00 (EP);
A61P9/10 (EP) (-)
Former IPC [1998/07]A61K31/56, A61K31/565
Former IPC [1995/52]A61K31/56
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1995/52]
TitleGerman:VERWENDUNG VON DHEA ODER DESSEN DERIVATE ZUR HERSTELLUNG EINES MEDIKAMENTS ZUR VORBEUGUNG VON PROGRESSIVER GEWEBE-NEKROSE, REPERFUSIONSSCHÄDIGUNG, BAKTERIELLER TRANSLOKATION UND VOM ATEMNOTSYNDROM BEI ERWACHSENEN[2002/21]
English:USE OF DHEA AND DERIVATIVES THEREOF FOR THE MANUFACTURE OF A MEDICAMENT FOR PREVENTING PROGRESSIVE TISSUE NECROSIS, REPERFUSION INJURY, BACTERIAL TRANSLOCATION AND ADULT RESPIRATORY DISTRESS SYNDROME[2002/21]
French:UTILISATION DE DHEA OU SES DERIVES POUR LA MANUFACTURE D'UN MEDICAMENT POUR PREVENIR LA NECROSE TISSULAIRE EVOLUTIVE, LES LESIONS CONSECUTIVES A LA REPERFUSION, LA TRANSLOCATION BACTERIENNE ET L'INSUFFISANCE RESPIRATOIRE AIGUE DES ETATS DE CHOCS[2002/21]
Former [1995/52]VERFAHREN ZUR VORBEUGUNG VON PROGRESSIVEN GEWEBE-NEKROSE, REPERFUSIONSSCHÄDIGUNG, BAKTERIELLER TRANSLOKATION UND VOM ATEMNOTSYNDROM BEI ERWACHSENEN
Former [1995/52]METHODS FOR PREVENTING PROGRESSIVE TISSUE NECROSIS, REPERFUSION INJURY, BACTERIAL TRANSLOCATION AND ADULT RESPIRATORY DISTRESS SYNDROME
Former [1995/52]PROCEDES PERMETTANT DE PREVENIR LA NECROSE TISSULAIRE EVOLUTIVE, LES LESIONS CONSECUTIVES A LA REPERFUSION, LA TRANSLOCATION BACTERIENNE ET L'INSUFFISANCE RESPIRATOIRE AIGUE DES ETATS DE CHOCS
Entry into regional phase09.08.1995National basic fee paid 
09.08.1995Search fee paid 
09.08.1995Designation fee(s) paid 
09.08.1995Examination fee paid 
Examination procedure30.09.1994Request for preliminary examination filed
International Preliminary Examining Authority: US
09.08.1995Examination requested  [1995/52]
12.05.1999Despatch of a communication from the examining division (Time limit: M04)
15.09.1999Reply to a communication from the examining division
04.02.2002Despatch of a communication from the examining division (Time limit: M02)
26.03.2002Reply to a communication from the examining division
13.06.2002Despatch of communication of intention to grant (Approval: Yes)
19.02.2003Communication of intention to grant the patent
19.05.2003Fee for grant paid
19.05.2003Fee for publishing/printing paid
20.11.2003Despatch of a communication from the examining division (Time limit: M04)
29.03.2004Reply to a communication from the examining division
Opposition(s)25.08.2005No opposition filed within time limit [2005/46]
Fees paidRenewal fee
20.03.1996Renewal fee patent year 03
24.02.1997Renewal fee patent year 04
26.03.1998Renewal fee patent year 05
22.02.1999Renewal fee patent year 06
21.02.2000Renewal fee patent year 07
21.02.2001Renewal fee patent year 08
22.03.2002Renewal fee patent year 09
24.03.2003Renewal fee patent year 10
22.03.2004Renewal fee patent year 11
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT24.11.2004
BE24.11.2004
DK24.02.2005
GR24.02.2005
LU08.03.2005
MC31.03.2005
PT24.04.2005
[2008/05]
Former [2007/26]AT24.11.2004
BE24.11.2004
DK24.02.2005
GR24.02.2005
LU08.03.2005
MC31.03.2005
Former [2007/16]AT24.11.2004
BE24.11.2004
DK24.02.2005
GR24.02.2005
LU31.03.2005
MC31.03.2005
Former [2006/14]AT24.11.2004
BE24.11.2004
DK24.02.2005
GR24.02.2005
MC31.03.2005
Former [2005/51]AT24.11.2004
BE24.11.2004
DK24.02.2005
GR24.02.2005
Former [2005/46]AT24.11.2004
DK24.02.2005
GR24.02.2005
Former [2005/36]AT24.11.2004
GR24.02.2005
Former [2005/26]GR24.02.2005
Documents cited:Search[X]US5162198  (EICH DAVID M [US], et al) [X] 1,5,7-9,14-16 * column 1, line 39 - column 2, line 5 * * column 6, line 9 - line 34 * * claims 1-5 *;
 [PX]US5206008  (LORIA ROGER [US]) [PX] 1,2,5,8,10-16 * column 4, line 21 - column 5, line 25 * * column 11, line 54 - column 13, line 12 * * claims 1-24 *;
 [X]  - D.BEN-NATHAN ET AL., "PROTECTIVE EFFECT OF DEHYDROEPIANDROSTERONE (DHEA) IN VIRAL AND BACTERIAL INFECTIONS", PUBLIC HEALTH REVIEWS, (ISRAEL), (1992), vol. 20, no. 1-2, page 177, XP002049297 [X] 1,2,5,10-16 * abstract *
 [X]  - W.JOTIS ET AL., "antimicrobial properties of testosterone and its intermediates", ANTONIE VAN LEEWENHOEK, NL, (1968), vol. 34, no. 3, pages 275 - 286, XP002049298 [X] 1,2,5 * abstract * * page 283, paragraph 3 - page 285, paragraph 1 *

DOI:   http://dx.doi.org/10.1007/BF02046449
 [X]  - G.B.GORDON ET AL., "REDUCTION OF ATHEROSCLEROSIS BY ADMINISTRATION OF DHEA", J.CLIN.INVEST, USA, (198808), vol. 82, no. 2, pages 712 - 720, XP002049299 [X] 1,5,9 * abstract * * page 712, column L, line 1 - column R, line 42 * * page 717, column R, paragraph 2 - page 719, column L, line 3 *

DOI:   http://dx.doi.org/10.1172/JCI113652
 [X]  - D.M.EICH ET AL., "INHIBITION OF ACCELERATED CORONARY ATHEROSCLEROSIS WITH DHEA IN THE HETEROTOPIC RABBIT MODEL OF CARDIAC TRANSPLANTATION", CIRCULATION, USA, (199301), vol. 87, no. 1, pages 261 - 269, XP002049300 [X] 1,5,9 * abstract * * page 261, column L, line 1 - page 262, column L, line 3 * * page 268, column L, line 9 - page 269, paragraph 2 *
 [X]  - B.A.ARANEO ET AL., "ADMINISTRATION OF DHEA TO BURNED MICE PRESERVES NORMAL IMMUNOLOGIC COMPETENCE", ARCH.SURG., USA, (199303), vol. 128, no. 3, pages 318 - 325, XP002049301 [X] 1,2,5,8,10-12,14-16 * abstract * * page 318, column L, line 1 - page 318, column R, line 20 * * page 322, column L, line 7 - page 322, column R, line 23 * * page 322, column R, paragraph 3 - page 324, column L, paragraph 4 *
 [X]  - R.M.LOGIA ET AL., IMMUNE RESPONSE FACILITATION AND RESISTANCE TO VIRUS AND BACTERIAL INFECTIONS WITH DHEA, BERLIN, NEW YORK, WALTER DE GRUYTER, (1990), XP002049302 [X] 1,2,5,8 * page 107, paragraph 1 - page 108, paragraph 3 * * page 110, line 8 - line 28 * * page 116, line 1 - line 6 * * page 110; figure 3 * * page 124, paragraph 4 - page 125, line 4 * * page 125, paragraph 4 *
International search[Y]US4898694  (SCHWARTZ ARTHUR G [US], et al);
 [X]US5110810  (EICH DAVID M [US], et al)
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.