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Extract from the Register of European Patents

EP About this file: EP0697111

EP0697111 - CELL TEST FOR ALZHEIMER'S DISEASE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  29.05.1998
Database last updated on 16.09.2024
Most recent event   Tooltip29.05.1998No opposition filed within time limitpublished on 15.07.1998 [1998/29]
Applicant(s)For all designated states
THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institute of Health, Office of Technology Transfer, Westwood Building, Box OTT
Bethesda, MD 20892-9902 / US
For all designated states
CORNELL RESEARCH FOUNDATION, INC.
20 Thornwood Drive, Suite 105
Ithaca, NY 14850 / US
[N/P]
Former [1996/08]For all designated states
THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institute of Health, Office of Technology Transfer, Westwood Building, Box OTT
Bethesda, MD 20892-9902 / US
For all designated states
CORNELL RESEARCH FOUNDATION, INC.
20 Thornwood Drive, Suite 105
Ithaca, NY 14850 / US
Inventor(s)01 / ALKON, Daniel, L.
6701 Bonaventure Court
Bethesda, MD 20817 / US
02 / ETCHEBERRIGARAY, Rene
12221 Village Square Terrace
Rockville, MD 20852 / US
03 / ETSURO, Ito
1-45-106, Minami 18-jo, Nishi 17-chome
Chuo-ku Sapporo 060 / JP
04 / GIBSON, Gary, E.
60 Fernwood Road
Larchmont, NY 10538 / US
[1996/08]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [1996/08]VOSSIUS & PARTNER
Postfach 86 07 67
D-81634 München / DE
Application number, filing date94915953.702.05.1994
[1996/08]
WO1994US04754
Priority number, dateUS1993005645603.05.1993         Original published format: US 56456
[1996/08]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9425872
Date:10.11.1994
[1994/25]
Type: A1 Application with search report 
No.:EP0697111
Date:21.02.1996
[1996/08]
Type: B1 Patent specification 
No.:EP0697111
Date:23.07.1997
Language:EN
[1997/30]
Search report(s)International search report - published on:EP10.11.1994
ClassificationIPC:G01N33/50
[1996/08]
CPC:
G01N33/6872 (EP,US); C07K14/4711 (EP,US); C07K16/18 (EP,US);
G01N33/5091 (EP,US); G01N33/6896 (EP,US); G01N2800/2821 (EP,US);
Y10S436/811 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1996/08]
TitleGerman:ZELL-TEST FÜR ALZHEIMERSCHE KRANKHEIT[1997/30]
English:CELL TEST FOR ALZHEIMER'S DISEASE[1996/08]
French:TEST EFFECTUE SUR DES CELLULES POUR DIAGNOSTIQUER LA MALADIE D'ALZHEIMER[1996/08]
Former [1996/08]ZELL-TEST FÜR ALZHEINERSCHE KRANKHEIT
Entry into regional phase01.12.1995National basic fee paid 
01.12.1995Designation fee(s) paid 
01.12.1995Examination fee paid 
Examination procedure10.11.1994Request for preliminary examination filed
International Preliminary Examining Authority: EP
01.12.1995Examination requested  [1996/08]
07.05.1996Despatch of communication of intention to grant (Approval: Yes)
24.09.1996Communication of intention to grant the patent
03.01.1997Fee for grant paid
03.01.1997Fee for publishing/printing paid
Opposition(s)24.04.1998No opposition filed within time limit [1998/29]
Fees paidRenewal fee
22.04.1996Renewal fee patent year 03
28.04.1997Renewal fee patent year 04
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Cited inInternational search[A]WO8909600  (MASSACHUSETTS INST TECHNOLOGY [US]) [A] 5,6,8* claim - *
 [XP]  - E.ITO ET AL., "A laboratory diagnosis of Alzheimer's Disease with patch-clamp and Ca2+-imaging techniques", NEUROSCIENCE RESEARCH, (199312), vol. 18, page 576 [XP] 1-21 * See abstract 615 *
 [XP]  - R.ETCHEBERRIGARAY ET AL., "Potassium channel dysfunction in fibroblasts identifies patients with Alzheimer disease", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA), (19930901), vol. 90, no. 17, pages 8209 - 8213 [XP] 1-12 * the whole document *
 [XP]  - E.ITO ET AL., "Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES (USA), (19940118), vol. 91, no. 2, pages 534 - 538 [XP] 13-21 * the whole document *
 [A]  - H-M.HUANG ET AL., "Inositol Phosphates and Intracellular calcium After Bradykinin Stimulation in Fibroblasts From Young, Normal Aged and Alzheimer Donors", NEUROBIOLOGY OF AGING, (1991), vol. 12, pages 469 - 473 [A] 13-21 * page 469 - page 470 *
 [A]  - A.GROSSMANN ET AL., "Intracellular calcium Response Is Reduced in CD4+ Lymphocytes in Alzheimer's Disease and in Older Persons with Down's Syndrome", NEUROBIOLOGY OF AGING, (199304), vol. 14, no. 2, pages 177 - 185 [A] 5,6,9,11,13,16,17,19,21 * page 177 - page 179 *
 [AD]  - B.SAKMANN ET AL., "Patch Clamp techniques for Studying Ionic Channels in Excitable Membranes", ANN. REV. PHYSIOL., (1984), vol. 46, pages 455 - 472 [AD] 1,4 * See the introduction *
 [AD]  - C.PETERSON ET AL., "Altered response of Fibroblasts From Aged and Alzheimer Donors to Drugs That Elevate Cytosolic Free Calcium", NEUROBIOLOGY OF AGING, (1988), vol. 9, no. 3, pages 261 - 266 [AD] 5-7,9-12 * the whole document *
 [AP]  - A.F.GHUYSEN-ITARD ET AL., "Loss of calcium-Homeostatic Mechanisms in Polymorphonuclear Leukocytes of demented and Nondemented Elderly Subjects", GERONTOLOGY, (199308), vol. 39, pages 163 - 169 [AP] 5-7,9-12 * the whole document *
Examination   - GERONTOLOGY, vol.39August 1993 pages 163 - 169 A.F.GHUYSEN-ITARD ET AL. 'Loss
    - of calcium-Homeostatic Mechanisms in Polymorphonuclear Leukocytes of demented and Nondemented Elderly Subjects'
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.