EP0730607 - NOVEL INTEGRIN-BINDING PEPTIDES [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 05.04.2002 Database last updated on 02.09.2024 | Most recent event Tooltip | 04.01.2008 | Lapse of the patent in a contracting state New state(s): IT | published on 06.02.2008 [2008/06] | Applicant(s) | For all designated states LA JOLLA CANCER RESEARCH FOUNDATION 10901 North Torrey Pines Road La Jolla, CA 92037 / US | [1996/37] | Inventor(s) | 01 /
RUOSLAHTI, Erkki P.O. Box 1054 Rancho Santa Fe, CA 92067 / US | 02 /
KOIVUNEN, Erkki VIIKINKAARI 5, BIOCENTER 1B PL56 HELSINKI UNIVERSITY, 00014 HELSINKI / FI | [1996/52] |
Former [1996/37] | 01 /
RUOSLAHTI, Erkki P.O. Box 1054 Rancho Santa Fe, CA 92067 / US | ||
02 /
KOIVUNEN, Erkki 4158 Decoro 66 San Diego, 92122 / US | Representative(s) | Uexküll & Stolberg Partnerschaft von Patent- und Rechtsanwälten mbB Beselerstraße 4 22607 Hamburg / DE | [N/P] |
Former [1996/37] | UEXKÜLL & STOLBERG Patentanwälte Beselerstrasse 4 22607 Hamburg / DE | Application number, filing date | 95903595.7 | 22.11.1994 | [1996/37] | WO1994US13542 | Priority number, date | US19930158001 | 24.11.1993 Original published format: US 158001 | US19940286861 | 04.08.1994 Original published format: US 286861 | [1996/37] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO9514714 | Date: | 01.06.1995 | Language: | EN | [1995/23] | Type: | A1 Application with search report | No.: | EP0730607 | Date: | 11.09.1996 | Language: | EN | The application published by WIPO in one of the EPO official languages on 01.06.1995 takes the place of the publication of the European patent application. | [1996/37] | Type: | B1 Patent specification | No.: | EP0730607 | Date: | 30.05.2001 | Language: | EN | [2001/22] | Search report(s) | International search report - published on: | EP | 01.06.1995 | Classification | IPC: | C07K14/75, C07K14/78, C07K14/705, A61K38/39, A61K38/00 | [1996/37] | CPC: |
C07K14/70546 (EP,US);
A61L27/227 (EP,US);
A61P17/00 (EP);
A61P19/10 (EP);
A61P35/00 (EP);
C07K14/75 (EP,US);
| Designated contracting states | BE, CH, DE, DK, FR, GB, IT, LI, NL, SE [1996/37] | Title | German: | NEUE INTEGRINBINDENDE PEPTIDE | [2001/22] | English: | NOVEL INTEGRIN-BINDING PEPTIDES | [1996/37] | French: | NOUVEAUX PEPTIDES FIXANT L'INTEGRINE | [1996/37] |
Former [1996/37] | NEUE INTEGRINBINDENDEN PEPTIDE | Entry into regional phase | 18.06.1996 | National basic fee paid | 18.06.1996 | Designation fee(s) paid | 18.06.1996 | Examination fee paid | Examination procedure | 22.06.1995 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 18.06.1996 | Examination requested [1996/37] | 21.08.1997 | Despatch of a communication from the examining division (Time limit: M06) | 26.02.1998 | Reply to a communication from the examining division | 19.05.1999 | Despatch of a communication from the examining division (Time limit: M04) | 20.09.1999 | Reply to a communication from the examining division | 26.07.2000 | Despatch of communication of intention to grant (Approval: Yes) | 27.11.2000 | Communication of intention to grant the patent | 27.02.2001 | Fee for grant paid | 27.02.2001 | Fee for publishing/printing paid | Divisional application(s) | EP98250245.2 / EP0906919 | Opposition(s) | 01.03.2002 | No opposition filed within time limit [2002/21] | Fees paid | Renewal fee | 11.11.1996 | Renewal fee patent year 03 | 10.11.1997 | Renewal fee patent year 04 | 27.11.1998 | Renewal fee patent year 05 | 25.11.1999 | Renewal fee patent year 06 | 28.11.2000 | Renewal fee patent year 07 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | BE | 30.05.2001 | CH | 30.05.2001 | IT | 30.05.2001 | LI | 30.05.2001 | NL | 30.05.2001 | DK | 30.08.2001 | SE | 30.08.2001 | [2008/06] |
Former [2003/45] | BE | 30.05.2001 | |
CH | 30.05.2001 | ||
LI | 30.05.2001 | ||
NL | 30.05.2001 | ||
DK | 30.08.2001 | ||
SE | 30.08.2001 | ||
Former [2003/08] | BE | 30.05.2001 | |
CH | 30.05.2001 | ||
LI | 30.05.2001 | ||
NL | 30.05.2001 | ||
SE | 30.08.2001 | ||
Former [2002/15] | BE | 30.05.2001 | |
CH | 30.05.2001 | ||
LI | 30.05.2001 | ||
SE | 30.08.2001 | ||
Former [2002/12] | BE | 30.05.2001 | |
SE | 30.08.2001 | ||
Former [2002/05] | SE | 30.08.2001 | Cited in | International search | [Y]WO9201464 (SCRIPPS RESEARCH INST [US]) [Y] 14-18,22-71* see Table 1 together with figures 5-7 * | [X] - C E PEISHOFF ET AL., "Investigation of conformational specificity oat GPIIb/IIIa; evaluation of conformationally constrained peptides", JOURNAL OF MEDICINAL CHEMISTRY., WASHINGTON US, (19921016), vol. 35, no. 21, pages 3962 - 3969 [X] 9-13,22-71 * see Table 1, compounds 11 and 13 * | [Y] - J SAMANEN ET AL., "Development of a small RGD peptide fibrinogen receptor antagonist with potent antiaggregatory activity in vitro", JOURNAL OF MEDICINAL CHEMISTRY., WASHINGTON US, (199110), vol. 34, no. 10, pages 3114 - 3125 [Y] 14-18,22-71 * see discussion, especially second paragraph * | [A] - E KOIVUNEN ET AL., "Selection of peptides binding to the alphaVbetaI integrin from phage display library", JOURNAL OF BIOLOGICAL CHEMISTRY, BALTIMORE, MD US, (19930925), vol. 268, no. 27, pages 20205 - 20210 [A] 1-71 * the whole document * | [A] - A P N SKUBITZ ET AL., "Synthetic peptides from the carboxy-terminal globular domain of the A chain of laminin: their ability to promote cell adhesion and neurite outgrowth, and interact with heparin and the beta1 integrin subunit", J CELL BIOL., NEW YORK, NY, USA, (199111), vol. 115, no. 4, pages 1137 - 1148 [A] 15-18 * see Table 1, second compound * | [PX] - E KOIVUNEN ET AL., "Isolation of a highly specific ligand for the alphaVbeta1 integrin from a phage display library", J CELL BIOL., NEW YORK, NY, USA, (199402), vol. 124, no. 3, pages 373 - 380 [PX] 1-8,22-71 * the whole document * | Examination | - BIOTechnology 13 (1995) 265 Proteins Struct Funct Genet 14 (1992) 509-515 J Biol Chem 266 (1991) 12809-12 |