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Extract from the Register of European Patents

EP About this file: EP0730607

EP0730607 - NOVEL INTEGRIN-BINDING PEPTIDES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  05.04.2002
Database last updated on 02.09.2024
Most recent event   Tooltip04.01.2008Lapse of the patent in a contracting state
New state(s): IT		published on 06.02.2008  [2008/06]
Applicant(s)For all designated states
LA JOLLA CANCER RESEARCH FOUNDATION
10901 North Torrey Pines Road
La Jolla, CA 92037 / US
[1996/37]
Inventor(s)01 / RUOSLAHTI, Erkki
P.O. Box 1054
Rancho Santa Fe, CA 92067 / US
02 / KOIVUNEN, Erkki
VIIKINKAARI 5, BIOCENTER 1B PL56
HELSINKI UNIVERSITY, 00014 HELSINKI / FI
[1996/52]
Former [1996/37]01 / RUOSLAHTI, Erkki
P.O. Box 1054
Rancho Santa Fe, CA 92067 / US
02 / KOIVUNEN, Erkki
4158 Decoro 66
San Diego, 92122 / US
Representative(s)Uexküll & Stolberg
Partnerschaft von
Patent- und Rechtsanwälten mbB
Beselerstraße 4
22607 Hamburg / DE
[N/P]
Former [1996/37]UEXKÜLL & STOLBERG
Patentanwälte Beselerstrasse 4
22607 Hamburg / DE
Application number, filing date95903595.722.11.1994
[1996/37]
WO1994US13542
Priority number, dateUS1993015800124.11.1993         Original published format: US 158001
US1994028686104.08.1994         Original published format: US 286861
[1996/37]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9514714
Date:01.06.1995
Language:EN
[1995/23]
Type: A1 Application with search report 
No.:EP0730607
Date:11.09.1996
Language:EN
The application published by WIPO in one of the EPO official languages on 01.06.1995 takes the place of the publication of the European patent application.
[1996/37]
Type: B1 Patent specification 
No.:EP0730607
Date:30.05.2001
Language:EN
[2001/22]
Search report(s)International search report - published on:EP01.06.1995
ClassificationIPC:C07K14/75, C07K14/78, C07K14/705, A61K38/39, A61K38/00
[1996/37]
CPC:
C07K14/70546 (EP,US); A61L27/227 (EP,US); A61P17/00 (EP);
A61P19/10 (EP); A61P35/00 (EP); C07K14/75 (EP,US);
C07K14/78 (EP,US); A61K38/00 (EP,US) (-)
Designated contracting statesBE,   CH,   DE,   DK,   FR,   GB,   IT,   LI,   NL,   SE [1996/37]
TitleGerman:NEUE INTEGRINBINDENDE PEPTIDE[2001/22]
English:NOVEL INTEGRIN-BINDING PEPTIDES[1996/37]
French:NOUVEAUX PEPTIDES FIXANT L'INTEGRINE[1996/37]
Former [1996/37]NEUE INTEGRINBINDENDEN PEPTIDE
Entry into regional phase18.06.1996National basic fee paid 
18.06.1996Designation fee(s) paid 
18.06.1996Examination fee paid 
Examination procedure22.06.1995Request for preliminary examination filed
International Preliminary Examining Authority: EP
18.06.1996Examination requested  [1996/37]
21.08.1997Despatch of a communication from the examining division (Time limit: M06)
26.02.1998Reply to a communication from the examining division
19.05.1999Despatch of a communication from the examining division (Time limit: M04)
20.09.1999Reply to a communication from the examining division
26.07.2000Despatch of communication of intention to grant (Approval: Yes)
27.11.2000Communication of intention to grant the patent
27.02.2001Fee for grant paid
27.02.2001Fee for publishing/printing paid
Divisional application(s)EP98250245.2  / EP0906919
Opposition(s)01.03.2002No opposition filed within time limit [2002/21]
Fees paidRenewal fee
11.11.1996Renewal fee patent year 03
10.11.1997Renewal fee patent year 04
27.11.1998Renewal fee patent year 05
25.11.1999Renewal fee patent year 06
28.11.2000Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipBE30.05.2001
CH30.05.2001
IT30.05.2001
LI30.05.2001
NL30.05.2001
DK30.08.2001
SE30.08.2001
[2008/06]
Former [2003/45]BE30.05.2001
CH30.05.2001
LI30.05.2001
NL30.05.2001
DK30.08.2001
SE30.08.2001
Former [2003/08]BE30.05.2001
CH30.05.2001
LI30.05.2001
NL30.05.2001
SE30.08.2001
Former [2002/15]BE30.05.2001
CH30.05.2001
LI30.05.2001
SE30.08.2001
Former [2002/12]BE30.05.2001
SE30.08.2001
Former [2002/05]SE30.08.2001
Cited inInternational search[Y]WO9201464  (SCRIPPS RESEARCH INST [US]) [Y] 14-18,22-71* see Table 1 together with figures 5-7 *
 [X]  - C E PEISHOFF ET AL., "Investigation of conformational specificity oat GPIIb/IIIa; evaluation of conformationally constrained peptides", JOURNAL OF MEDICINAL CHEMISTRY., WASHINGTON US, (19921016), vol. 35, no. 21, pages 3962 - 3969 [X] 9-13,22-71 * see Table 1, compounds 11 and 13 *
 [Y]  - J SAMANEN ET AL., "Development of a small RGD peptide fibrinogen receptor antagonist with potent antiaggregatory activity in vitro", JOURNAL OF MEDICINAL CHEMISTRY., WASHINGTON US, (199110), vol. 34, no. 10, pages 3114 - 3125 [Y] 14-18,22-71 * see discussion, especially second paragraph *
 [A]  - E KOIVUNEN ET AL., "Selection of peptides binding to the alphaVbetaI integrin from phage display library", JOURNAL OF BIOLOGICAL CHEMISTRY, BALTIMORE, MD US, (19930925), vol. 268, no. 27, pages 20205 - 20210 [A] 1-71 * the whole document *
 [A]  - A P N SKUBITZ ET AL., "Synthetic peptides from the carboxy-terminal globular domain of the A chain of laminin: their ability to promote cell adhesion and neurite outgrowth, and interact with heparin and the beta1 integrin subunit", J CELL BIOL., NEW YORK, NY, USA, (199111), vol. 115, no. 4, pages 1137 - 1148 [A] 15-18 * see Table 1, second compound *
 [PX]  - E KOIVUNEN ET AL., "Isolation of a highly specific ligand for the alphaVbeta1 integrin from a phage display library", J CELL BIOL., NEW YORK, NY, USA, (199402), vol. 124, no. 3, pages 373 - 380 [PX] 1-8,22-71 * the whole document *
Examination   - BIOTechnology 13 (1995) 265 Proteins Struct Funct Genet 14 (1992) 509-515 J Biol Chem 266 (1991) 12809-12
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.