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EP About this file: EP0783893

EP0783893 - INHIBITION OF ABNORMAL GROWTH OF SYNOVIAL CELLS USING IL-6 ANTAGONIST AS ACTIVE INGREDIENT [Right-click to bookmark this link]
Former [1997/29]	RHEUMATOID ARTHRITIS REMEDY CONTAINING IL-6 ANTAGONIST AS ACTIVE INGREDIENT
	[2011/38]
Status	No opposition filed within time limit Status updated on 08.02.2013 Database last updated on 05.07.2024
Most recent event Tooltip	08.02.2013	No opposition filed within time limit	published on 13.03.2013 [2013/11]
Applicant(s)	For all designated states CHUGAI SEIYAKU KABUSHIKI KAISHA 5-1, Ukima 5-chome, Kita-ku Tokyo 115 / JP
	For all designated states Kishimoto, Tadamitsu 3-5-31, Nakano-cho, Tondabayashi-shi Osaka 584 / JP
	[2012/14]
Former [1997/29]	For all designated states CHUGAI SEIYAKU KABUSHIKI KAISHA 5-1, Ukima 5-chome, Kita-ku Tokyo 115 / JP
	For all designated states Kishimoto, Tadamitsu 3-5-31, Nakano-cho, Tondabayashi-shi Osaka 584 / JP
Inventor(s)	01 / KISHIMOTO, Tadamitsu 3-5-31, Nakano-cho-Tondabayashi-shi Osaka 584 / JP
	02 / MIHARA, Masahiko c/o Chugai Seiyaku Kabushiki Kaisha 135, Komakado 1-chome-Gotenba-shi Shizuoka 412 / JP
	03 / MORIYA, Yoichiro c/o Chugai Seiyaku Kabushiki Kaisha 135, Komakado 1-chome-Gotenba-shi Shizuoka 412 / JP
	04 / OHSUGI, Yoshiyuki c/o Chugai Seiyaku Kabushiki Kaisha 135, Komakado 1-chome-Gotenba-shi Shizuoka 412 / JP
	[2011/41]
Former [1997/29]	01 / KISHIMOTO, Tadamitsu 3-5-31, Nakano-cho-Tondabayashi-shi Osaka 584 / JP
	02 / MIHARA, Masahiko-Chugai Seiyaku Kabushiki Kaisha 135, Komakado 1-chome-Gotenba-shi Shizuoka 412 / JP
	03 / MORIYA, Yoichiro-Chugai Seiyaku Kabushiki Kaisha 135, Komakado 1-chome-Gotenba-shi Shizuoka 412 / JP
	04 / OHSUGI, Yoshiyuki-Chugai Seiyaku Kabushiki Kaisha 135, Komakado 1-chome-Gotenba-shi Shizuoka 412 / JP
Representative(s)	Vossius & Partner Patentanwälte Rechtsanwälte mbB Siebertstrasse 3 81675 München / DE
	[N/P]
Former [2012/14]	Vossius & Partner Siebertstrasse 4 81675 München / DE
Former [2008/35]	Vossius & Partner Siebertstrasse 3 81675 München / DE
Former [1997/29]	VOSSIUS & PARTNER Siebertstrasse 4 81675 München / DE
Application number, filing date	95921130.1	07.06.1995
	[1997/29]
	WO1995JP01144
Priority number, date	JP19940244035	07.10.1994 Original published format: JP 24403594
	[1997/29]
Filing language	JA
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9611020
	Date:	18.04.1996
	Language:	EN
	[1996/17]
	Type:	A1 Application with search report
	No.:	EP0783893
	Date:	16.07.1997
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 18.04.1996 takes the place of the publication of the European patent application.
	[1997/29]
	Type:	B1 Patent specification
	No.:	EP0783893
	Date:	04.04.2012
	Language:	EN
	[2012/14]
Search report(s)	International search report - published on:	JP	18.04.1996
	(Supplementary) European search report - dispatched on:	EP	27.02.1998
Classification	IPC:	A61K39/395, A61K38/20, // C12P21/08, C07K16/24, C07K16/28	[1997/29]
	CPC:	C07K16/244 (EP); A61P19/02 (EP); A61P19/04 (EP); A61P29/00 (EP); A61P37/00 (EP); A61P43/00 (EP); (+) C07K16/248 (EP); C07K16/2866 (EP); A61K38/00 (EP) (-)
Designated contracting states	AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1997/29]
Title	German:	HEMMUNG DES ABNORMALEN WACHSTUMS VON SYNOVIALZELLEN DURCH IL-6-ANTAGONISTEN ALS WIRKSTOFF	[2012/13]
	English:	INHIBITION OF ABNORMAL GROWTH OF SYNOVIAL CELLS USING IL-6 ANTAGONIST AS ACTIVE INGREDIENT	[2011/38]
	French:	INHIBITION DE LA CROISSANCE ANORMALE DE CELLULES SYNOVIALES A L' AIDE D' UN ANTAGONISTE D'INTERLEUKINE 6 COMME PRINCIPE ACTIF	[2011/38]
	Former [1997/29]	ARZNEI GEGEN RHEUMATOIDE ARTHRITIS, DIE EINEN IL-6-ANTAGONISTEN ALS AKTIVEN BESTANDTEIL ENTHÄLT
	Former [1997/29]	RHEUMATOID ARTHRITIS REMEDY CONTAINING IL-6 ANTAGONIST AS ACTIVE INGREDIENT
	Former [1997/29]	MEDICAMENT CONTRE LA POLYARTHRITE RHUMATOIDE CONTENANT UN ANTAGONISTE D'INTERLEUKINE 6 COMME PRINCIPE ACTIF
Entry into regional phase	07.04.1997	Translation filed
	06.05.1997	National basic fee paid
	06.05.1997	Search fee paid
	06.05.1997	Designation fee(s) paid
	06.05.1997	Examination fee paid
Examination procedure	12.07.1995	Request for preliminary examination filed International Preliminary Examining Authority: JP
	06.05.1997	Examination requested [1997/29]
	20.11.1998	Despatch of a communication from the examining division (Time limit: M04)
	30.03.1999	Reply to a communication from the examining division
	06.08.1999	Despatch of a communication from the examining division (Time limit: M06)
	15.02.2000	Reply to a communication from the examining division
	13.04.2000	Despatch of a communication from the examining division (Time limit: M04)
	26.06.2000	Reply to a communication from the examining division
	01.10.2002	Despatch of a communication from the examining division (Time limit: M04)
	06.02.2003	Reply to a communication from the examining division
	30.01.2006	Despatch of a communication from the examining division (Time limit: M06)
	04.08.2006	Reply to a communication from the examining division
	18.09.2008	Despatch of a communication from the examining division (Time limit: M04)
	21.01.2009	Reply to a communication from the examining division
	24.04.2009	Observations by third parties
	08.07.2009	Despatch of a communication from the examining division (Time limit: M04)
	17.07.2009	Reply to a communication from the examining division
	16.09.2011	Communication of intention to grant the patent
	26.01.2012	Fee for grant paid
	26.01.2012	Fee for publishing/printing paid
Divisional application(s)	EP09000787.3 / EP2077120
	EP09009350.1 / EP2107070
	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 20.11.1998
Opposition(s)	07.01.2013	No opposition filed within time limit [2013/11]
Fees paid	Renewal fee
	06.05.1997	Renewal fee patent year 03
	29.06.1998	Renewal fee patent year 04
	29.06.1999	Renewal fee patent year 05
	28.06.2000	Renewal fee patent year 06
	29.06.2001	Renewal fee patent year 07
	01.07.2002	Renewal fee patent year 08
	30.06.2003	Renewal fee patent year 09
	30.06.2004	Renewal fee patent year 10
	30.06.2005	Renewal fee patent year 11
	29.06.2006	Renewal fee patent year 12
	29.06.2007	Renewal fee patent year 13
	28.02.2008	Renewal fee patent year 14
	24.06.2009	Renewal fee patent year 15
	31.03.2010	Renewal fee patent year 16
	27.06.2011	Renewal fee patent year 17
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	GR	05.07.2012
	[2012/50]
Documents cited:	Search	[X]EP0399429 (TORAY INDUSTRIES [JP]) [X] 1-4,7-9 * claims 1-6 * * page 2, line 13 - line 53 *;
		[X]EP0409607 (KISHIMOTO TADAMITSU [JP]) [X] 1,2,4-8 * claims 1-8 *;
		[X]DE3939706 (CENTRE REGIONAL DE TRANSFUSION SANGUINE ET AL) [X] 1,2,4,7 * claims 3-7 ** page 2, line 61 - page 3, line 20 *;
		[X]WO9107986 (SCHERING CORP [US], et al) [X] 1-4,7,8 * claims 1-9,11,12 *;
		[XD]WO9219759 (CHUGAI PHARMACEUTICAL CO LTD [JP]) [XD] 1,2,4-8 * abstract *;
		[XD]US5210075 (SCHOLZ WOLFGANG [US], et al) [XD] 1,2,7,9 * claims 1,7,10,13-15 * * column 28, line 63 - column 29, line 49 *;
		[X]EP0572118 (TOSOH CORP [JP], et al) [X] 1,2,4,7,8 * claims 1-5,15-19 * * page 6, column 9, line 17 - line 34 *;
		[XY]FR2694767 (INNOTHERAPIE LAB SA [FR]) [X] 1,2,4-8 * claims 1-6 * [Y] 9;
		[X]EP0617126 (AJINOMOTO KK [JP]) [X] 1-9 * claims 1-4,20-23 * * page 12, line 44 - line 51 *;
		[L]EP0628639 (CHUGAI PHARMACEUTICAL CO LTD [JP]);
		[Y] - HIRANO T ET AL, "BIOLOGICAL AND CLINICAL ASPECTS OF INTERLEUKIN 6", IMMUNOLOGY TODAY, (19901201), vol. 11, no. 12, pages 443 - 449, XP000179752 [Y] 9 * page 444, column R, line 9 - page 445, column L, line 12 * DOI: http://dx.doi.org/10.1016/0167-5699(90)90173-7
	International search	[X] - J. RHEUMATOL., Vol. 15, No. 11, (1988), HARIGAI M. et al., pp. 1616-1622.
		[X] - TOSO KENKYU HOKOKU, JOURNAL OF TOSOH RESEARCH, Vol. 35, No. 2, (1991), YASUKAWA K. et al., pp. 77-91.
		[Y] - EUR. J. IMMUNOL., Vol. 18, (1988), MATSUDA T. et al., pp. 951-956.
		[Y] - J. IMMUNOL., Vol. 143, No. 9, (1989), HIRATA U. et al., pp. 2900-2906.
	Examination	JPH04187646
		- J. WIIDENES, "Interleukin-6 antibodies in rheumatoid arthritis", JOURNAL OF INTERFERON RESEARCH, (1994), vol. 14, pages 297 - 298
		- H. HEREMANS ET AL, "Protective effect of anti-interleukin (IL)-6 antibody against endotoxin, associated with paradoxically increased IL-6 levels", EUROPEAN JOURNAL OF IMMUNOLOGY, (1992), vol. 22, pages 2395 - 2401
		- R. BELLOMO, "the cytokine network in the critically ill", ANEASTHESIA AND INTENSIVE CARE, (1992), vol. 20, no. 3, pages 288 - 302
		- ATSUO MURATA ET AL, "possible implications of cytokines in the pathophysiology of acute pancreatitis", SAISHIN IGAKU, (1992), vol. 47, no. 11, pages 49 - 56
	other	JPH04187645
		FR2694767

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