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EP About this file: EP0772454

EP0772454 - ANTISENSE OLIGONUCLEOTIDES AGAINST HEPATITIS B VIRAL REPLICATION [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 25.02.2005 Database last updated on 17.07.2024
Most recent event Tooltip	25.02.2005	Application deemed to be withdrawn	published on 13.04.2005 [2005/15]
Applicant(s)	For all designated states GEORGETOWN UNIVERSITY 37th & "O" Streets, Northwest Ryan Administration Building Washington, DC 20057 / US
	[N/P]
Former [1997/20]	For all designated states GEORGETOWN UNIVERSITY 37th & "O" Streets, Northwest Ryan Administration Building Washington, DC 20057 / US
Inventor(s)	01 / KORBA, Brent E. 8255 Stone Trail Court Laurel, MD 20707 / US
	02 / GERIN, John L. 8910 Melwood Road Bethesda, MD 20817 / US
	[1997/20]
Representative(s)	Mercer, Christopher Paul, et al Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB
	[N/P]
Former [1997/20]	Mercer, Christopher Paul, et al Carpmaels & Ransford 43, Bloomsbury Square London WC1A 2RA / GB
Application number, filing date	95926752.7	28.07.1995
	[1997/20]
	WO1995US09143
Priority number, date	US19940281106	28.07.1994 Original published format: US 281106
	[1997/20]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9603152
	Date:	08.02.1996
	Language:	EN
	[1996/07]
	Type:	A1 Application with search report
	No.:	EP0772454
	Date:	14.05.1997
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 08.02.1996 takes the place of the publication of the European patent application.
	[1997/20]
Search report(s)	International search report - published on:	US	08.02.1996
	(Supplementary) European search report - dispatched on:	EP	27.11.1998
Classification	IPC:	A61K48/00, C12N15/11	[2004/26]
	CPC:	C12N15/1131 (EP,US); A61P31/12 (EP); A61K38/00 (EP,US); C12N2310/3125 (EP,US); C12N2310/315 (EP,US)
	Former IPC [1997/20]	A61K48/00, C07H21/04
Designated contracting states	AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1997/20]
Title	German:	ANTISENS-OLIGONUKLEOTIDE GEGEN DIE REPLIKATION DES HEPATITUS B-VIRUS	[1997/20]
	English:	ANTISENSE OLIGONUCLEOTIDES AGAINST HEPATITIS B VIRAL REPLICATION	[1997/20]
	French:	OLIGONUCLEOTIDES ANTISENS CONTRE LA REPLICATION VIRALE DE L'HEPATITE B	[1997/20]
Entry into regional phase	27.02.1997	National basic fee paid
	27.02.1997	Search fee paid
	27.02.1997	Designation fee(s) paid
	27.02.1997	Examination fee paid
Examination procedure	28.02.1996	Request for preliminary examination filed International Preliminary Examining Authority: US
	03.03.1997	Examination requested [1997/20]
	07.02.2001	Despatch of a communication from the examining division (Time limit: M08)
	17.10.2001	Reply to a communication from the examining division
	25.11.2002	Despatch of a communication from the examining division (Time limit: M06)
	18.09.2003	Reply to a communication from the examining division
	24.05.2004	Communication of intention to grant the patent
	05.10.2004	Application deemed to be withdrawn, date of legal effect [2005/15]
	05.11.2004	Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time [2005/15]
Request for further processing for:	18.09.2003	Request for further processing filed
	18.09.2003	Full payment received (date of receipt of payment) Request granted
	17.10.2003	Decision despatched
Fees paid	Renewal fee
	27.02.1997	Renewal fee patent year 03
	27.07.1998	Renewal fee patent year 04
	02.07.1999	Renewal fee patent year 05
	03.07.2000	Renewal fee patent year 06
	12.07.2001	Renewal fee patent year 07
	12.07.2002	Renewal fee patent year 08
	23.07.2003	Renewal fee patent year 09
	14.07.2004	Renewal fee patent year 10
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[PX]WO9519433 (TARGETECH INC [US]) [PX] 1-4 * the whole document *;
		[E]WO9639502 (HOFFMANN LA ROCHE [CH], et al) [E] 1-4 * page 4, line 27 - page 5, line 27 * * page 12, line 18 - line 23 * * page 18, line 32 - page 20, line 13 * * figures 3,4 * * page 12, line 54 *;
		[E]WO9703211 (ISIS PHARMACEUTICALS INC [US], et al) [E] 1-4 * abstract * * page 16, line 16 - line 24 ** claim - *;
		[X] - "Hepatitis B virus", INTERNATIONAL ANTIVIRAL NEWS, (1994), vol. 2, page 59, XP002085113 [X] 1 * column R, line 3 - line 22 *
		[A] - KORBA B ET AL, "Inhibition of hepatitis B virus replication in vitro by antisense oligonucleotides", ANTIVIRAL RES.;(1994) 23, SUPPL.1, 78, XP002085114 [A] 1 * Abstract 80 *
		[DA] - HIRSCH R C ET AL, "CIS-ACTING SEQUENCES REQUIRED FOR ENCAPSIDATION OF DUCK HEPATITIS BVIRUS PREGENOMIC RNA", JOURNAL OF VIROLOGY, (199106), vol. 65, no. 6, pages 3309 - 3316, XP000614651 [DA] 1-4 * the whole document *
		[PX] - KORBA B E ET AL, "ANTISENSE OLIGONUCLEOTIDES ARE EFFECTIVE INHIBITORS OF HEPATITIS B VIRUS REPLICATION IN VITRO", ANTIVIRAL RESEARCH, (1995), vol. 28, pages 225 - 242, XP000603334 [PX] 1 * the whole document * DOI: http://dx.doi.org/10.1016/0166-3542(95)00050-V
	International search	[Y]US5190931 (INOUYE MASAYORI [US])
		[Y] - JOURNAL OF VIROLOGY, Volume 67, Number 6, issued June 1993, POLLACK et al., "An RNA Stem-Loop Structure Directs Hepatitis B Virus Genomic RNA Encapsidation", pages 3254-3263.
		[Y] - NUCLEIC ACIDS RESEARCH, Volume 21, Number 17, issued 25 August 1993, KNAUS et al., "The Encapsidation Signal on the Hepatitis B Virus RNA Pregenome Forms a Stem-Loop Structure That is Critical for its Function", pages 3967-3975.
		[Y] - JOURNAL OF GENERAL VIROLOGY, Volume 71, issued 1990, GOODARZI et al., "Antisense Oligodeoxyribonucleotides Inhibit the Expression of the Gene for Hepatitis B Virus Surface Antigen", pages 3021-3025.

The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.

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