blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP0788364

EP0788364 - TREATMENT OF UROGENITAL CANCER WITH BORON NEUTRON CAPTURE THERAPY [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  17.10.2003
Database last updated on 22.05.2024
Most recent event   Tooltip17.10.2003Application deemed to be withdrawnpublished on 03.12.2003  [2003/49]
Applicant(s)For all designated states
EMORY UNIVERSITY
1380 S. Oxford Road
Atlanta, GA 30321 / US
[N/P]
Former [2003/01]For all designated states
Emory University
1380 S. Oxford Road
Atlanta, GA 30321 / US
Former [1997/33]For all designated states
EMORY UNIVERSITY
1380 South Oxford Road
Atlanta, GA 30322 / US
Inventor(s)01 / SCHINAZI, Raymond F.
1524 Regency Walk Drive
Decatur, GA 30033 / US
02 / KEANE, Thomas E.
5378 Dunwoody Club Circle
Dunwoody, GA 30360 / US
03 / LIOTTA, Dennis C.
251 Montrose Drive
McDonough, GA 30253 / US
[1997/33]
Representative(s)Hallybone, Huw George, et al
Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[N/P]
Former [2000/24]Hallybone, Huw George, et al
CARPMAELS AND RANSFORD 43 Bloomsbury Square
London WC1A 2RA / GB
Former [1998/22]Bassett, Richard Simon, et al
Eric Potter Clarkson, Park View House, 58 The Ropewalk
Nottingham NG1 5DD / GB
Former [1997/33]Bassett, Richard, et al
ERIC POTTER & CLARKSON St. Mary's Court St. Mary's Gate
Nottingham NG1 1LE / GB
Application number, filing date95939803.306.11.1995
[1997/33]
WO1995US14450
Priority number, dateUS1994033475904.11.1994         Original published format: US 334759
[1997/33]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9614073
Date:17.05.1996
Language:EN
[1996/22]
Type: A1 Application with search report 
No.:EP0788364
Date:13.08.1997
Language:EN
The application published by WIPO in one of the EPO official languages on 17.05.1996 takes the place of the publication of the European patent application.
[1997/33]
Search report(s)International search report - published on:US17.05.1996
(Supplementary) European search report - dispatched on:EP19.03.1998
ClassificationIPC:A61K31/69, A61K31/70, A61K41/00
[1998/17]
CPC:
C07H21/00 (EP,US); A61K41/0095 (EP,US); A61K49/085 (EP,US);
A61K49/10 (EP,US); A61P13/02 (EP); A61P15/00 (EP);
A61P31/12 (EP); A61P35/00 (EP); C07H19/06 (EP,US);
C07H19/10 (EP,US); C07H19/20 (EP,US); C07H23/00 (EP,US);
C12N15/10 (EP,US); C12N15/113 (EP,US); C12N9/1276 (EP,US);
C12Q1/6816 (EP,US); C12Q1/6827 (EP,US); C12Q1/6886 (EP,US);
C12N2310/318 (EP,US); C12N2310/33 (EP,US); C12N2310/3527 (EP,US) (-)
Former IPC [1997/33]A61K31/69, A61K31/70
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1997/33]
TitleGerman:BEHANDLUNG DES UROGENITALKREBSES MIT DER BOR-NEUTRONENEINFANGTHERAPIE[1997/33]
English:TREATMENT OF UROGENITAL CANCER WITH BORON NEUTRON CAPTURE THERAPY[1997/33]
French:TRAITEMENT DE CANCERS UROGENITAUX PAR THERAPIE AU BORE ET A CAPTURE DE NEUTRONS[1997/33]
Entry into regional phase03.06.1997National basic fee paid 
03.06.1997Search fee paid 
03.06.1997Designation fee(s) paid 
03.06.1997Examination fee paid 
Examination procedure03.06.1996Request for preliminary examination filed
International Preliminary Examining Authority: US
03.06.1997Examination requested  [1997/33]
26.07.2000Despatch of a communication from the examining division (Time limit: M06)
02.02.2001Reply to a communication from the examining division
10.05.2001Despatch of a communication from the examining division (Time limit: M07)
13.12.2001Reply to a communication from the examining division
06.03.2002Despatch of a communication from the examining division (Time limit: M04)
16.07.2002Reply to a communication from the examining division
15.11.2002Communication of intention to grant the patent
27.05.2003Application deemed to be withdrawn, date of legal effect  [2003/49]
02.07.2003Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2003/49]
Fees paidRenewal fee
10.11.1997Renewal fee patent year 03
10.11.1998Renewal fee patent year 04
12.11.1999Renewal fee patent year 05
13.11.2000Renewal fee patent year 06
14.11.2001Renewal fee patent year 07
13.11.2002Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[PXY]WO9515333  (UNIV EMORY [US]) [PX] 1 * page 5 - page 6 * * page 68, paragraph 2 * * page 19, line 4 - page 26, line 9 * * page 66, line 21 - line 25; claim - * [Y] 1-11;
 [PX]WO9526359  (UNIV CALIFORNIA [US], et al) [PX] 1,2 * page 29; claim - *;
 [X]  - ISHIWATA, KIICHI ET AL, "Synthesis and radiation dosimetry of 4-borono-2-[18F]fluoro-DL- phenylalanine: a target compound for PET and boron neutron capture therapy", CHEMABS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, XP002057180 [X] 1,2 * abstract *
 [XY]  - CHARNG-JUI CHEN ET AL, "SYNTHESIS AND CHARACTERIZATION OF LOIGOMERIC NIDO-CARBORANYL PHOSPHATE DIESTER CONJUGATES TO ANTIBODY AND ANTIBODY FRAGMENTS FOR POTENTIAL USE IN BORON NEUTRON CAPTURE THERAPY OF SOLID TUMORS", BIOCONJUGATE CHEMISTRY, (19941101), vol. 5, no. 6, pages 557 - 564, XP000484174 [XY] 1-11 * figure 1 *

DOI:   http://dx.doi.org/10.1021/bc00030a011
 [X]  - ORN-ANONG PETTERSSON ET AL., "ACCUMULATION OF 10B IN THE CENTRAL DEGENERATIVE AREAS OF HUMAN GLIOMAS AND COLON CARCINOMA SPHEROIDS AFTER SULFHYDRYL BORON HYDRIDE ADMINISTRATION.", CANCER RESEARCH, MD US, (19920315), vol. 52, pages 1587 - 1591, XP002057172 [X] 1,2 * abstract * * page 1587, column 1, paragraph 2 - paragraph 3 *
 [X]  - GOUDGAON N.M. ET AL., "BORON CONTAINING PYRIMIDINES, NUCLEOSIDES, AND OLIGONUCLEOTIDES FOR NEUTRON CAPTURE THERAPY.", NUCLEOSIDES NUCLEOTIDES, (1994), vol. 13, no. 1-3, pages 849 - 880, XP002057173 [X] 1-11 * the whole document *
 [DX]  - SCHINAZI, RAYMOND F. ET AL, "Synthesis of 5-(dihydroxyboryl)-2'-deoxyuridine and related boron-containing pyrimidines", J. ORG. CHEM. (1985), 50(6), 841-7 CODEN: JOCEAH;ISSN: 0022-3263, (1985), XP002057174 [DX] 1,2 * abstract *

DOI:   http://dx.doi.org/10.1021/jo00206a024
 [X]  - FULCRAND-EL KATTAN, GERALDINE ET AL, "Synthesis and Biological Properties of5-o-Carboranyl-1-(2-deoxy-2- fluoro-.beta.-D-arabinofuranosyl)uracil", J. MED. CHEM. (1994), 37(16), 2583-8 CODEN: JMCMAR;ISSN: 0022-2623, (1994), XP002057175 [X] 1,2 * table - *

DOI:   http://dx.doi.org/10.1021/jm00042a011
 [X]  - FULCRAND-EL KATTAN, GERALDINE ET AL, "Carboranyl Oligonucleotides. 2. Synthesis and Physicochemical Properties of Dodecathymidylate Containing 5-(o-Carboran-1-yl)-2'- deoxyuridine", J. AM. CHEM. SOC. (1994), 116(17), 7494-501 CODEN: JACSAT;ISSN: 0002-7863, (1994), XP002057176 [X] 1,2 * figure - *

DOI:   http://dx.doi.org/10.1021/ja00096a004
 [X]  - VERRIJK, R. ET AL, "Pharmacokinetics in melanoma-bearing mice of 5-dihydroxyboryl-6- propyl- 2 - thiouracil (BPTU), a candidate compound for boron neutron capture therapy", BR. J. CANCER (1994), 69(4), 641-7 CODEN: BJCAAI;ISSN: 0007-0920, (1994), XP002057177 [X] 1,2 * figure 1; table - *
 [PX]  - LESNIKOWSKI, Z. J. ET AL, "Boron neutron capture therapy of cancers: nucleic bases, nucleosides, and oligonucleotides as potential boron carriers", POL. J. CHEM. (1995), 69(6), 827-40 CODEN: PJCHDQ;ISSN: 0137-5083, (1995), XP002057178 [PX] 1-11 * page 829, paragraph 3 *
 [XY]  - SCHINAZI, RAYMOND F. ET AL, "Carboranyl oligonucleotides for antisense technology and boron neutron capture therapy of cancers", ACS SYMP. SER. (1994), 580(CARBOHYDRATE MODIFICATIONS IN ANTISENSE RESEARCH), 169-82 CODEN: ACSMC8;ISSN: 0097-6156, (1994), XP002057179 [X] 1,2 * table - * [Y] 1-11
 [X]  - SCHWEMMER B. ET AL., "Specific androgen uptake in rat prostatic carcinoma: a prerequisite for the use of borated androgens in boron neutron capture therapy.", J. OF UROLOGY, (1987), vol. 137, no. 4 part 2, page 358a, XP002057187 [X] 1,2 * abstract *
International search[Y]US4516535  (RUSSELL JR JOHN L [US], et al);
 [AP]US5405598  (SCHINAZI RAYMOND F [US], et al)
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.