EP0788364 - TREATMENT OF UROGENITAL CANCER WITH BORON NEUTRON CAPTURE THERAPY [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 17.10.2003 Database last updated on 22.05.2024 | Most recent event Tooltip | 17.10.2003 | Application deemed to be withdrawn | published on 03.12.2003 [2003/49] | Applicant(s) | For all designated states EMORY UNIVERSITY 1380 S. Oxford Road Atlanta, GA 30321 / US | [N/P] |
Former [2003/01] | For all designated states Emory University 1380 S. Oxford Road Atlanta, GA 30321 / US | ||
Former [1997/33] | For all designated states EMORY UNIVERSITY 1380 South Oxford Road Atlanta, GA 30322 / US | Inventor(s) | 01 /
SCHINAZI, Raymond F. 1524 Regency Walk Drive Decatur, GA 30033 / US | 02 /
KEANE, Thomas E. 5378 Dunwoody Club Circle Dunwoody, GA 30360 / US | 03 /
LIOTTA, Dennis C. 251 Montrose Drive McDonough, GA 30253 / US | [1997/33] | Representative(s) | Hallybone, Huw George, et al Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB | [N/P] |
Former [2000/24] | Hallybone, Huw George, et al CARPMAELS AND RANSFORD 43 Bloomsbury Square London WC1A 2RA / GB | ||
Former [1998/22] | Bassett, Richard Simon, et al Eric Potter Clarkson, Park View House, 58 The Ropewalk Nottingham NG1 5DD / GB | ||
Former [1997/33] | Bassett, Richard, et al ERIC POTTER & CLARKSON St. Mary's Court St. Mary's Gate Nottingham NG1 1LE / GB | Application number, filing date | 95939803.3 | 06.11.1995 | [1997/33] | WO1995US14450 | Priority number, date | US19940334759 | 04.11.1994 Original published format: US 334759 | [1997/33] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO9614073 | Date: | 17.05.1996 | Language: | EN | [1996/22] | Type: | A1 Application with search report | No.: | EP0788364 | Date: | 13.08.1997 | Language: | EN | The application published by WIPO in one of the EPO official languages on 17.05.1996 takes the place of the publication of the European patent application. | [1997/33] | Search report(s) | International search report - published on: | US | 17.05.1996 | (Supplementary) European search report - dispatched on: | EP | 19.03.1998 | Classification | IPC: | A61K31/69, A61K31/70, A61K41/00 | [1998/17] | CPC: |
C07H21/00 (EP,US);
A61K41/0095 (EP,US);
A61K49/085 (EP,US);
A61K49/10 (EP,US);
A61P13/02 (EP);
A61P15/00 (EP);
A61P31/12 (EP);
A61P35/00 (EP);
C07H19/06 (EP,US);
C07H19/10 (EP,US);
C07H19/20 (EP,US);
C07H23/00 (EP,US);
C12N15/10 (EP,US);
C12N15/113 (EP,US);
C12N9/1276 (EP,US);
C12Q1/6816 (EP,US);
C12Q1/6827 (EP,US);
C12Q1/6886 (EP,US);
|
Former IPC [1997/33] | A61K31/69, A61K31/70 | Designated contracting states | AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1997/33] | Title | German: | BEHANDLUNG DES UROGENITALKREBSES MIT DER BOR-NEUTRONENEINFANGTHERAPIE | [1997/33] | English: | TREATMENT OF UROGENITAL CANCER WITH BORON NEUTRON CAPTURE THERAPY | [1997/33] | French: | TRAITEMENT DE CANCERS UROGENITAUX PAR THERAPIE AU BORE ET A CAPTURE DE NEUTRONS | [1997/33] | Entry into regional phase | 03.06.1997 | National basic fee paid | 03.06.1997 | Search fee paid | 03.06.1997 | Designation fee(s) paid | 03.06.1997 | Examination fee paid | Examination procedure | 03.06.1996 | Request for preliminary examination filed International Preliminary Examining Authority: US | 03.06.1997 | Examination requested [1997/33] | 26.07.2000 | Despatch of a communication from the examining division (Time limit: M06) | 02.02.2001 | Reply to a communication from the examining division | 10.05.2001 | Despatch of a communication from the examining division (Time limit: M07) | 13.12.2001 | Reply to a communication from the examining division | 06.03.2002 | Despatch of a communication from the examining division (Time limit: M04) | 16.07.2002 | Reply to a communication from the examining division | 15.11.2002 | Communication of intention to grant the patent | 27.05.2003 | Application deemed to be withdrawn, date of legal effect [2003/49] | 02.07.2003 | Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time [2003/49] | Fees paid | Renewal fee | 10.11.1997 | Renewal fee patent year 03 | 10.11.1998 | Renewal fee patent year 04 | 12.11.1999 | Renewal fee patent year 05 | 13.11.2000 | Renewal fee patent year 06 | 14.11.2001 | Renewal fee patent year 07 | 13.11.2002 | Renewal fee patent year 08 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [PXY]WO9515333 (UNIV EMORY [US]) [PX] 1 * page 5 - page 6 * * page 68, paragraph 2 * * page 19, line 4 - page 26, line 9 * * page 66, line 21 - line 25; claim - * [Y] 1-11; | [PX]WO9526359 (UNIV CALIFORNIA [US], et al) [PX] 1,2 * page 29; claim - *; | [X] - ISHIWATA, KIICHI ET AL, "Synthesis and radiation dosimetry of 4-borono-2-[18F]fluoro-DL- phenylalanine: a target compound for PET and boron neutron capture therapy", CHEMABS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, XP002057180 [X] 1,2 * abstract * | [XY] - CHARNG-JUI CHEN ET AL, "SYNTHESIS AND CHARACTERIZATION OF LOIGOMERIC NIDO-CARBORANYL PHOSPHATE DIESTER CONJUGATES TO ANTIBODY AND ANTIBODY FRAGMENTS FOR POTENTIAL USE IN BORON NEUTRON CAPTURE THERAPY OF SOLID TUMORS", BIOCONJUGATE CHEMISTRY, (19941101), vol. 5, no. 6, pages 557 - 564, XP000484174 [XY] 1-11 * figure 1 * DOI: http://dx.doi.org/10.1021/bc00030a011 | [X] - ORN-ANONG PETTERSSON ET AL., "ACCUMULATION OF 10B IN THE CENTRAL DEGENERATIVE AREAS OF HUMAN GLIOMAS AND COLON CARCINOMA SPHEROIDS AFTER SULFHYDRYL BORON HYDRIDE ADMINISTRATION.", CANCER RESEARCH, MD US, (19920315), vol. 52, pages 1587 - 1591, XP002057172 [X] 1,2 * abstract * * page 1587, column 1, paragraph 2 - paragraph 3 * | [X] - GOUDGAON N.M. ET AL., "BORON CONTAINING PYRIMIDINES, NUCLEOSIDES, AND OLIGONUCLEOTIDES FOR NEUTRON CAPTURE THERAPY.", NUCLEOSIDES NUCLEOTIDES, (1994), vol. 13, no. 1-3, pages 849 - 880, XP002057173 [X] 1-11 * the whole document * | [DX] - SCHINAZI, RAYMOND F. ET AL, "Synthesis of 5-(dihydroxyboryl)-2'-deoxyuridine and related boron-containing pyrimidines", J. ORG. CHEM. (1985), 50(6), 841-7 CODEN: JOCEAH;ISSN: 0022-3263, (1985), XP002057174 [DX] 1,2 * abstract * DOI: http://dx.doi.org/10.1021/jo00206a024 | [X] - FULCRAND-EL KATTAN, GERALDINE ET AL, "Synthesis and Biological Properties of5-o-Carboranyl-1-(2-deoxy-2- fluoro-.beta.-D-arabinofuranosyl)uracil", J. MED. CHEM. (1994), 37(16), 2583-8 CODEN: JMCMAR;ISSN: 0022-2623, (1994), XP002057175 [X] 1,2 * table - * DOI: http://dx.doi.org/10.1021/jm00042a011 | [X] - FULCRAND-EL KATTAN, GERALDINE ET AL, "Carboranyl Oligonucleotides. 2. Synthesis and Physicochemical Properties of Dodecathymidylate Containing 5-(o-Carboran-1-yl)-2'- deoxyuridine", J. AM. CHEM. SOC. (1994), 116(17), 7494-501 CODEN: JACSAT;ISSN: 0002-7863, (1994), XP002057176 [X] 1,2 * figure - * DOI: http://dx.doi.org/10.1021/ja00096a004 | [X] - VERRIJK, R. ET AL, "Pharmacokinetics in melanoma-bearing mice of 5-dihydroxyboryl-6- propyl- 2 - thiouracil (BPTU), a candidate compound for boron neutron capture therapy", BR. J. CANCER (1994), 69(4), 641-7 CODEN: BJCAAI;ISSN: 0007-0920, (1994), XP002057177 [X] 1,2 * figure 1; table - * | [PX] - LESNIKOWSKI, Z. J. ET AL, "Boron neutron capture therapy of cancers: nucleic bases, nucleosides, and oligonucleotides as potential boron carriers", POL. J. CHEM. (1995), 69(6), 827-40 CODEN: PJCHDQ;ISSN: 0137-5083, (1995), XP002057178 [PX] 1-11 * page 829, paragraph 3 * | [XY] - SCHINAZI, RAYMOND F. ET AL, "Carboranyl oligonucleotides for antisense technology and boron neutron capture therapy of cancers", ACS SYMP. SER. (1994), 580(CARBOHYDRATE MODIFICATIONS IN ANTISENSE RESEARCH), 169-82 CODEN: ACSMC8;ISSN: 0097-6156, (1994), XP002057179 [X] 1,2 * table - * [Y] 1-11 | [X] - SCHWEMMER B. ET AL., "Specific androgen uptake in rat prostatic carcinoma: a prerequisite for the use of borated androgens in boron neutron capture therapy.", J. OF UROLOGY, (1987), vol. 137, no. 4 part 2, page 358a, XP002057187 [X] 1,2 * abstract * | International search | [Y]US4516535 (RUSSELL JR JOHN L [US], et al); | [AP]US5405598 (SCHINAZI RAYMOND F [US], et al) |