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Extract from the Register of European Patents

EP About this file: EP0808325

EP0808325 - ANDROSTANE AND PREGNANE SERIES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  23.11.2001
Database last updated on 03.10.2024
Most recent event   Tooltip17.04.2015Change - lapse in a contracting statepublished on 20.05.2015  [2015/21]
Applicant(s)For all designated states
COCENSYS, INC.
213 Technology Drive
Irvine, CA 92718 / US
[1997/48]
Inventor(s)01 / LAN, Nancy, C.
522 Hermosa Street
South Pasadena, CA 91030 / US
02 / GEE, Kelvin, W.
47 Urey Court
Irvine, CA 92715 / US
03 / BOLGER, Michael, B.
3411 Rowena Drive
Los Alamitos, CA 90720 / US
04 / TAHIR, Hasan
F-396 Sarita Vihar
New Delhi 110 044 / IN
05 / PURDY, Robert
7150 Shoreline Drive No. 3304
San Diego, CA 92122 / US
06 / UPASANI, Ravindra, B.
63 Montecilo
Fothill Ranch, CA 92610 / US
 [2001/02]
Former [1997/48]01 / LAN, Nancy, C.
522 Hermosa Street
South Pasadena, CA 91030 / US
02 / GEE, Kelvin, W.
47 Urey Court
Irvine, CA 92715 / US
03 / BOLGER, Michael, B.
3411 Rowena Drive
Los Alamitos, CA 90720 / US
04 / TAHIR, Hasan
F-396 Sarita Vihar
New Delhi 110 044 / IN
05 / PURDY, Robert
7150 Shoreline Drive 3304
San Diego, CA 92122 / US
06 / UPASANI, Ravindra, B.
63 Montecilo
Fothill Ranch, CA 92610 / US
Representative(s)Chapman, Paul William, et al
Kilburn & Strode LLP
20 Red Lion Street
London
WC1R 4PJ / GB
[N/P]
Former [1997/48]Chapman, Paul William, et al
Kilburn & Strode, 30 John Street
London WC1N 2DD / GB
Application number, filing date95942879.822.11.1995
[1997/48]
WO1995US15210
Priority number, dateUS1994034692623.11.1994         Original published format: US 346926
[1997/48]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9616076
Date:30.05.1996
Language:EN
[1996/25]
Type: A1 Application with search report 
No.:EP0808325
Date:26.11.1997
Language:EN
The application published by WIPO in one of the EPO official languages on 30.05.1996 takes the place of the publication of the European patent application.
[1997/48]
Type: B1 Patent specification 
No.:EP0808325
Date:17.01.2001
Language:EN
[2001/03]
Search report(s)International search report - published on:US30.05.1996
(Supplementary) European search report - dispatched on:EP04.11.1997
ClassificationIPC:C07J9/00, C07J5/00, A61K31/56
[1997/48]
CPC:
C07J41/005 (EP); A61P23/00 (EP); A61P25/00 (EP);
A61P25/08 (EP); A61P25/12 (EP); A61P25/22 (EP);
A61P25/24 (EP); C07J5/0015 (EP); C07J7/002 (EP);
C07J7/007 (EP); C07J9/00 (EP) (-)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [1997/48]
TitleGerman:ANDROSTAN- UND PREGNANSERIEN FÜR DIE ALLOSTERISCHE MODULATION DES GABA-REZEPTORS[1997/48]
English:ANDROSTANE AND PREGNANE SERIES FOR ALLOSTERIC MODULATION OF GABA RECEPTOR[1997/48]
French:SERIES DE L'ANDROSTANE ET DE LA PREGNANE PRODUISANT UNE MODULATION ALLOSTERIQUE DU RECEPTEUR DU GABA[1997/48]
Entry into regional phase20.06.1997National basic fee paid 
20.06.1997Search fee paid 
20.06.1997Designation fee(s) paid 
20.06.1997Examination fee paid 
Examination procedure21.06.1996Request for preliminary examination filed
International Preliminary Examining Authority: US
20.06.1997Examination requested  [1997/48]
16.09.1998Despatch of a communication from the examining division (Time limit: M06)
28.05.1999Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
28.07.1999Reply to a communication from the examining division
15.09.1999Despatch of communication of intention to grant (Approval: Yes)
15.03.2000Communication of intention to grant the patent
04.05.2000Fee for grant paid
04.05.2000Fee for publishing/printing paid
Opposition(s)18.10.2001No opposition filed within time limit [2002/02]
Request for further processing for:28.07.1999Request for further processing filed
28.07.1999Full payment received (date of receipt of payment)
Request granted
13.08.1999Decision despatched
Fees paidRenewal fee
27.11.1997Renewal fee patent year 03
27.11.1998Renewal fee patent year 04
08.11.1999Renewal fee patent year 05
10.11.2000Renewal fee patent year 06
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Former [2002/26]ES17.01.2001
Documents cited:Search[Y]US3953429  (COOK MARTIN CHRISTOPHER, et al) [Y] 2,9-16 * examples 17-21 *;
 [Y]WO9303732  (COCENSYS INC [US]) [Y] 2,9-16 * page 45 - page 46; examples 26-28 *;
 [Y]WO9305786  (COCENSYS INC [US]) [Y] 2,9-16 * examples 5,6 *;
 [PX]WO9427608  (COCENSYS INC [US]) [PX] 2,7,9-16* example 25 *;
 [Y]  - PHILLIPPS G H, "STRUCTURE-ACTIVITY RELATIONSHIPS IN STEROIDAL ANAESTHETICS", NOL. MECH. GEN. ANAESTH. GLAXO SYMPOSIUM, (19740101), pages 32 - 47, XP000600765 [Y] 2,9-16 * page 35, paragraph 3 * * page 37, compounds 21 and 22 *
 [Y]  - PHILLIPPS G H, "STRUCTURE-ACTIVITY RELATIONSHIPS IN STEROIDAL ANAESTHETICS", JOURNAL OF STEROID BIOCHEMISTRY, (197505), vol. 6, no. 5, pages 607 - 613, XP000600716 [Y] 2,9-16 * page 608, compounds XXIII and XXIV *; page 609, column 2, paragraph 1 *

DOI:   http://dx.doi.org/10.1016/0022-4731(75)90041-2
 [Y]  - R. PURDY ET AL, "Synthesis, Metabolism and Pharmacological Activity of 3.alpha.-Hydroxy Steroids Which Potentiate GABA-Receptor Mediated Chloride Ion Uptake in Rat Cerebral Cortical Synaptoneurosomes", JOURNAL OF MEDICINAL CHEMISTRY., WASHINGTON US, (199006), vol. 33, no. 6, pages 1572 - 1581, XP002044395 [Y] 2,9-16 * page 1576, column 2; examples 3A,31; table II *

DOI:   http://dx.doi.org/10.1021/jm00168a008
International search[A]US5120723  (GEE KELVIN W [US], et al);
 [Y]US5232917  (BOLGER MICHAEL [US], et al);
 [AP]US5371077  (SCHROEPFER JR GEORGE J [US], et al)
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.