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Extract from the Register of European Patents

EP About this file: EP0765871

EP0765871 - Substituted Quinoline-2-carboxamides, their preparation and their use as prolyle-4-hydroxylase Inhibitors [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  04.02.2005
Database last updated on 18.03.2026
Most recent event   Tooltip04.01.2008Lapse of the patent in a contracting state
New state(s): PT		published on 06.02.2008  [2008/06]
Applicant(s)For all designated states
FIBROGEN, INC.
225 Gateway Boulevard
South San Francisco, CA 94080 / US
[N/P]
Former [2002/31]For all designated states
FibroGen, Inc.
225 Gateway Boulevard
South San Francisco, CA 94080 / US
Former [1997/14]For all designated states
HOECHST AKTIENGESELLSCHAFT
Brüningstrasse 50
65929 Frankfurt am Main / DE
Inventor(s)01 / Weidmann, Klaus, Dr.
Scheibenbuschweg 2
61476 Kronberg / DE
02 / Baringhaus, Karl-Heinz, Dr.
Weingartenstrasse 31
61200 Wölfersheim / DE
03 / Tschank, Georg, Dr.
Pariser Strasse 30
55270 Klein-Winterheim / DE
04 / Bickel, Martin, Dr.
Mittelstedter Weg 3
61348 Bad Homburg / DE
[1997/14]
Representative(s)Janssen, Bernd Christian, et al
Uexküll & Stolberg Partnerschaft von
Patent- und Rechtsanwälten mbB
Beselerstrasse 4
22607 Hamburg / DE
[N/P]
Former [2002/22]Janssen, Bernd Christian, et al
Uexküll & Stolberg Patentanwälte Beselerstrasse 4
22607 Hamburg / DE
Application number, filing date96115110.720.09.1996
[1997/14]
Priority number, dateDE199513626328.09.1995         Original published format: DE 19536263
DE199610517013.02.1996         Original published format: DE 19605170
[1997/14]
Filing languageDE
Procedural languageDE
PublicationType: A1 Application with search report 
No.:EP0765871
Date:02.04.1997
Language:DE
[1997/14]
Type: B1 Patent specification 
No.:EP0765871
Date:31.03.2004
Language:DE
[2004/14]
Search report(s)(Supplementary) European search report - dispatched on:EP29.01.1997
ClassificationIPC:C07D215/60, C07D215/16, C07D215/48, A61K31/47
[1997/14]
CPC data not yet available
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   NL,   PT,   SE [1997/14]
TitleGerman:Substituierte Chinolin-2-Carbonsäureamide, ihre Herstellung und ihre Verwendung als Prolyl-4-hydroylase Inhibitoren[1997/14]
English:Substituted Quinoline-2-carboxamides, their preparation and their use as prolyle-4-hydroxylase Inhibitors[1997/14]
French:Dérivés de quinoline-2-carboxamide, leur préparation et leur utilisation comme inhibiteur de la prolyl-4-hydroxylase[1997/14]
Examination procedure02.10.1997Examination requested  [1997/49]
30.08.1999Despatch of a communication from the examining division (Time limit: M06)
13.06.2000Reply to a communication from the examining division
24.09.2001Despatch of a communication from the examining division (Time limit: M08)
11.07.2002Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
13.08.2002Reply to a communication from the examining division
14.04.2003Despatch of a communication from the examining division (Time limit: M06)
25.08.2003Reply to a communication from the examining division
15.10.2003Communication of intention to grant the patent
27.01.2004Fee for grant paid
27.01.2004Fee for publishing/printing paid
Opposition(s)04.01.2005No opposition filed within time limit [2005/12]
Request for further processing for:13.08.2002Request for further processing filed
13.08.2002Full payment received (date of receipt of payment)
Request granted
03.09.2002Decision despatched
13.06.2000Request for further processing filed
13.06.2000Full payment received (date of receipt of payment)
Request granted
28.06.2000Decision despatched
Fees paidRenewal fee
30.09.1998Renewal fee patent year 03
30.09.1999Renewal fee patent year 04
02.10.2000Renewal fee patent year 05
01.10.2001Renewal fee patent year 06
07.08.2002Renewal fee patent year 07
04.09.2003Renewal fee patent year 08
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipFI31.03.2004
IE31.03.2004
NL31.03.2004
DK30.06.2004
GR30.06.2004
SE30.06.2004
PT31.08.2004
AT20.09.2004
LU20.09.2004
BE30.09.2004
CH30.09.2004
LI30.09.2004
[2008/06]
Former [2007/16]FI31.03.2004
IE31.03.2004
NL31.03.2004
DK30.06.2004
GR30.06.2004
SE30.06.2004
AT20.09.2004
LU20.09.2004
BE30.09.2004
CH30.09.2004
LI30.09.2004
Former [2006/12]FI31.03.2004
IE31.03.2004
NL31.03.2004
DK30.06.2004
GR30.06.2004
SE30.06.2004
AT20.09.2004
BE30.09.2004
CH30.09.2004
LI30.09.2004
Former [2005/51]FI31.03.2004
IE31.03.2004
DK30.06.2004
GR30.06.2004
SE30.06.2004
BE30.09.2004
Former [2005/19]FI31.03.2004
IE31.03.2004
DK30.06.2004
GR30.06.2004
SE30.06.2004
Former [2005/18]FI31.03.2004
DK30.06.2004
GR30.06.2004
SE30.06.2004
Former [2004/41]FI31.03.2004
GR30.06.2004
SE30.06.2004
Former [2004/40]FI31.03.2004
SE30.06.2004
Documents cited:Search[YD]   FRANKLIN,J.F. ET AL.: "Approaches to the design of anti-fibrotic drugs", BIOCHEM.SOC.TRANS., vol. 19, 1991, pages 812 - 815, XP002022664 [YD] 1-32 * column W *
 [X]   BRESLOW,D.S. ET AL.: "Synthesis of Antimalerials. V. The Syntheis of Certain 4-Aminoquinoline Derivatives", J.AM.CHEM.SOC., vol. 68, 1946, WASHINGTON, pages 1232 - 1238, XP002022665 [X] 31 * seihe Seite 1233, Table I und Formeln rechts unten *
 [X]   KANEKO,C. ET AL.: "The Isomerisation of 1aH-Oxazirino[2,3-a]quinoline 1a-carbonitrile ....", CHEM.PHARM.BULL., vol. 15, no. 5, 1967, TOKYO, pages 663 - 669, XP002022666 [X] 31 * siehe Seite 664, Formel IVa, IVb *
 [X]   FATTORUSSO,E. ET AL.: "Isolation of 3,4-dihydroxyquinoline2-carboxylic acid from the sponge Aplysina aerophoba", GAZZ.CHIM.ITAL., vol. 101, 1971, ROM, pages 104 - 105, XP002022667 [X] 31 * siehe Seite 105, Formel I *
 [X]   HANNAH,E.D. ET AL.: "Removal of tolyl-sulphonyl groups from sulfonamides. III. some N-(tolyl-p-sulphonyl) glycine esters", J.CHEM.SOC. C, no. 4, 1967, pages 256 - 261, XP002022668 [X] 31 * Seite 256,Verbindung V, RN 14370-68-4 *
 [X]   BOGER,D.L. ET AL.: "(-)Sandramycin: Totoal Syntesei and Preliminary DNA Binding Properties", J.AM.CHEM.SOC., vol. 115, 1993, WASHINGTON, pages 11624 - 11625, XP002022669 [X] 31 * siehe Seite 11624, Formel 25 *
 [X]   KONISHI,M. ET AL.: "Structures of BBM-928 A,B and C....", J.AM.CHEM.SOC., vol. 103, no. 5, 1981, WASHINGTON, pages 1241 - 1243, XP002022670 [X] 31 * siehe Seite 1242, Formel 3 *
 [X]   BAYNE,D.W.ET AL.: "Synthesis of 2-Acyl-3-hydroxyquinolines Embodying a Novel Variant of the Smiles Rearrangement", J.CHEM.SOC.,CHEM.COMMUM., no. 19, 1975, LONDON, pages 782 - 783, XP002022671 [X] 32 * siehe Seite 783, Formel 7 a - c, e *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.