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EP About this file: EP0780123

EP0780123 - Beta-hydroxybutyric acid or acetoacetic acid or salts or esters therof for use in improving cerebral function [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 18.04.2003 Database last updated on 26.06.2024
Most recent event Tooltip	18.04.2003	No opposition filed within time limit	published on 04.06.2003 [2003/23]
Applicant(s)	For all designated states BTG INTERNATIONAL LIMITED 10 Fleet Place, Limeburner Lane London EC4M 7SB / GB
	[N/P]
Former [2001/17]	For all designated states BTG INTERNATIONAL LIMITED 10 Fleet Place, Limeburner Lane London EC4M 7SB / GB
Former [1997/26]	For all designated states Shimizu Pharmaceutical Co., Ltd. 235, Miyakami Shimizu-shi, Shizuoka 424 / JP
Inventor(s)	01 / Hiraide, Atsushi, M.D. 1-7-19-206, Shibahara-cho Toyonaka-shi, Osaka 560 / JP
	02 / Dohi, Sekiko, Ph.D. Shimizu-Pharmaceutical Co., Ltd., 235, Miyakami Shimizu-shi, Shizuoka 424 / JP
	03 / Suzuki, Motohisa Shimizu-Pharmaceutical Co., Ltd., 235, Miyakami Shimizu-shi, Shizuoka 424 / JP
	04 / Shiba, Yoshihiro Shimizu-Pharmaceutical Co., Ltd., 235, Miyakami Shimizu-shi, Shizuoka 424 / JP
	[1997/26]
Representative(s)	Weisert, Annekäte, et al Patentanwälte Kraus & Weisert Thomas-Wimmer-Ring 15 80539 München / DE
	[N/P]
Former [1997/26]	Weisert, Annekäte, Dipl.-Ing. Dr.-Ing., et al Patentanwälte Kraus Weisert & Partner Thomas-Wimmer-Ring 15 80539 München / DE
Application number, filing date	96118764.8	22.11.1996
	[1997/26]
Priority number, date	JP19950337750	01.12.1995 Original published format: JP 33775095
	JP19960202671	31.07.1996 Original published format: JP 20267196
	JP19960202676	01.08.1996 Original published format: JP 20267696
	JP19960299247	24.10.1996 Original published format: JP 29924796
	[1997/26]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	EP0780123
	Date:	25.06.1997
	Language:	EN
	[1997/26]
	Type:	B1 Patent specification
	No.:	EP0780123
	Date:	12.06.2002
	Language:	EN
	[2002/24]
Search report(s)	(Supplementary) European search report - dispatched on:	EP	23.04.1997
Classification	IPC:	A61K31/191, A61K31/22	[2001/19]
	CPC:	A61K31/19 (EP,US); A61K31/22 (EP,US); A61P25/00 (EP); A61P25/28 (EP); A61P3/00 (EP); A61P9/00 (EP); (+) A61P9/10 (EP) (-)
	Former IPC [1997/26]	A61K31/19, A61K31/22
Designated contracting states	DE, FR, GB [1997/26]
Title	German:	Betahydroxybuttersäure oder Acetoessigsäure oder deren Salze oder Ester zur Verwendung zur Verbesserung der Gehirnfunktion	[1997/26]
	English:	Beta-hydroxybutyric acid or acetoacetic acid or salts or esters therof for use in improving cerebral function	[1997/26]
	French:	L'acide bêta-hydroxybutyrique ou l'acide acétoacétique ou leurs sels ou esters pour l'utilisation dans l'amélioration du fonctionnement cérébral	[1997/26]
Examination procedure	11.12.1997	Examination requested [1998/07]
	20.03.1998	Despatch of a communication from the examining division (Time limit: M04)
	30.06.1998	Reply to a communication from the examining division
	25.02.2000	Despatch of a communication from the examining division (Time limit: M04)
	31.05.2000	Reply to a communication from the examining division
	20.03.2001	Date of oral proceedings
	05.04.2001	Despatch of communication of intention to grant (Approval: No)
	05.04.2001	Minutes of oral proceedings despatched
	28.09.2001	Despatch of communication of intention to grant (Approval: later approval)
	20.12.2001	Communication of intention to grant the patent
	15.03.2002	Fee for grant paid
	15.03.2002	Fee for publishing/printing paid
Divisional application(s)	EP01122563.8 / EP1188437
Opposition(s)	13.03.2003	No opposition filed within time limit [2003/23]
Fees paid	Renewal fee
	09.11.1998	Renewal fee patent year 03
	11.11.1999	Renewal fee patent year 04
	06.11.2000	Renewal fee patent year 05
	22.11.2001	Renewal fee patent year 06
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[Y]RU2007168 ;
		[Y]JPS57183748 ;
		[Y]US4346107 (CAVAZZA CLAUDIO, et al) [Y] 1-6* column 2, line 17 - line 48 *;
		[X]GB2126082 (SCHULZE HEINRICH, et al) [X] 1-6 * page 1, line 79 - page 2, line 68; claims 1,5,6 *;
		[X]US5116868 (CHEN CHUNG-HO [US], et al) [X] 1-6 * claims 1,5 *;
		[X] - ALBERT S.Y.CHANG ET AL., "Hypoxia and beta-hydroxybutyrate acutely reduce glucose extraction by the brain in anesthetized dogs", CAN.J.PHYSIOL.PHARMACOL., (1993), vol. 71, no. 7, pages 465 - 472, XP000652713 [X] 1-6 * abstract * * page 465, column L * * page 470, column R, paragraph 4 *
		[Y] - CLAUDIA ROBERTSON ET AL., "Dietary nonprotein calories and cerebral infarction size in rats", STROKE, (1992), vol. 23, no. 4, pages 564 - 568, XP000652742 [Y] 1-6 * abstract * * page 564, column R * * page 568, column L, paragraph 1 *
		[Y] - BENDIKOV ET AL., "Effect of sodium hydroxybutyrate on cerebral circulation and regional vasomotor reflexes", MEDLINE, Knight-Ridder, XP002029059 [Y] 1-6 * abstract *
		[ ] - BIULL.EKSP.BIOL.MED., (1979), vol. 88, no. 11, pages 555 - 557
		[Y] - DATABASE WPI, 1, Derwent World Patents Index, vol. 94, no. 33, Database accession no. 94-270349, XP002029060 & RU2007168 C 19940215 (KIRG MED INST) [Y] 1-6 * abstract *
		[Y] - DATABASE WPI, 1, Derwent World Patents Index, vol. 82, no. 51, Database accession no. 82-10255J, XP002029061 & JPS57183748 A 19821112 (DENKI KAGAKU KOGYO KK) [Y] 1-6 * abstract *
		[Y] - ALAN A. ARTRU ET AL., "gamma-hydroxybutyrate: cerebral metabolic, vascular, and protective effects", JOURNAL OF NEUROCHEMISTRY, (1980), vol. 35, no. 5, pages 1114 - 1119, XP000652714 [Y] 1-6 * abstract * DOI: http://dx.doi.org/10.1111/j.1471-4159.1980.tb07866.x
	by applicant	JPS58201746
		- OWEN ET AL., J. CLIN. INVEST., (1967), vol. 46, no. 10, pages 1589 - 1595
		- FUJII ET AL., JPN. J. ACUTE MED., (1993), vol. 4, no. 5, page 484

The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.

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