EP0863917 - TARGETED CYTOTOXIC ANTHRACYCLINE ANALOGS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 06.08.2004 Database last updated on 06.07.2024 | Most recent event Tooltip | 06.08.2004 | No opposition filed within time limit | published on 22.09.2004 [2004/39] | Applicant(s) | For all designated states The Administrators of the Tulane Educational Fund 1430 Tulane Avenue, SL 13 New Orleans, LA 70112 / US | [2003/12] |
Former [2001/49] | For all designated states Zentaris AG Weissmüllerstrasse 45 60314 Frankfurt/Main / DE | ||
Former [1998/38] | For all designated states ASTA Medica Aktiengesellschaft An der Pikardie 10 D-01277 Dresden / DE | Inventor(s) | 01 /
SCHALLY, Andrew V., Tulane University Med. Ctr School of Medicine, 1430 Tulane Avenue New Orleans, LA 70112-2699 / US | 02 /
NAGY, Attila A., Tulane University Med. Ctr School of Medicine, 1430 Tulane Avenue New Orleans, LA 70112-2699 / US | 03 /
CAI, Ren-Zhi, Tulane University Med. Ctr School of Medicine, 1430 Tulane Avenue New Orleans, LA 70112-2699 / US | [1998/38] | Representative(s) | Nauwald, Gunter Zentaris AG Patente/Marken Meissner Strasse 35 D-01445 Radebeul / DE | [N/P] |
Former [2003/12] | Nauwald, Gunter Zentaris AG Patente/Marken Meissner Strasse 35 D-01445 Radebeul / DE | ||
Former [2001/37] | (deleted) | ||
Former [1998/38] | Sander, Uwe c/o ASTA MEDICA AKTIENGESELLSCHAFT, Meissner Strasse 35 01435 Radebeul / DE | Application number, filing date | 96938216.7 | 14.11.1996 | [1998/38] | WO1996EP05029 | Priority number, date | US19950562652 | 27.11.1995 Original published format: US 562652 | [1998/38] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO9719954 | Date: | 05.06.1997 | Language: | EN | [1997/24] | Type: | A1 Application with search report | No.: | EP0863917 | Date: | 16.09.1998 | Language: | EN | The application published by WIPO in one of the EPO official languages on 05.06.1997 takes the place of the publication of the European patent application. | [1998/38] | Type: | B1 Patent specification | No.: | EP0863917 | Date: | 01.10.2003 | Language: | EN | [2003/40] | Search report(s) | International search report - published on: | EP | 05.06.1997 | Classification | IPC: | C07K7/23, A61K47/48 | [1998/38] | CPC data not yet available | Designated contracting states | AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1998/38] | Title | German: | ZIELGERICHTETE, ZYTOTOXISCHE ANTHRACYCLIN-ANALOGE | [1998/38] | English: | TARGETED CYTOTOXIC ANTHRACYCLINE ANALOGS | [1998/38] | French: | ANALOGUES CYTOTOXIQUES CIBLES D'ANTHRACYCLINE | [1998/38] | Entry into regional phase | 13.05.1998 | National basic fee paid | 13.05.1998 | Designation fee(s) paid | 13.05.1998 | Examination fee paid | Examination procedure | 31.05.1997 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 13.05.1998 | Examination requested [1998/38] | 13.05.2002 | Despatch of a communication from the examining division (Time limit: M08) | 13.01.2003 | Reply to a communication from the examining division | 19.03.2003 | Communication of intention to grant the patent | 18.06.2003 | Fee for grant paid | 18.06.2003 | Fee for publishing/printing paid | Divisional application(s) | EP03010988.8 / EP1384710 | Opposition(s) | 02.07.2004 | No opposition filed within time limit [2004/39] | Fees paid | Renewal fee | 11.11.1998 | Renewal fee patent year 03 | 10.11.1999 | Renewal fee patent year 04 | 19.01.2001 | Renewal fee patent year 05 | 27.10.2001 | Renewal fee patent year 06 | 31.10.2002 | Renewal fee patent year 07 | Penalty fee | Additional fee for renewal fee | 30.11.2000 | 05   M06   Fee paid on   19.01.2001 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [DX]US4299822 (ISRAEL MERVYN, et al) [DX] 1,32,33 * example -; claim - *; | [X]GB2124224 (STANFORD RES INST INT) [X] 1,32,33 * example -; claim - *; | [DX]EP0434960 (ERBA CARLO SPA [IT]) [DX] 1,32,33 * example -; claim - *; | [DA]EP0450461 (SCHALLY ANDREW VICTOR [US], et al) [DA] 1,2,32-36 * the whole document *; | [A]EP0624377 (BRISTOL MYERS SQUIBB CO [US]) [A] 1,32,33 * reaction schemes 12, 15, 16, 18;; examples 8,9,14,15,23 * * examples 24,28,48,49 * * examples 61,70,71; claim - *; | [DX] - A. CHERIF AND D. FARQUHAR, "N-(5,5-Diacetoxypent-1-yl)doxorubicin: A New Intensely Potent Doxorubicin Analogue", JOURNAL OF MEDICINAL CHEMISTRY, WASHINGTON US, (19920821), vol. 35, no. 17, pages 3208 - 3214, XP002029565 [DX] 1,32,33 * see chart I, Scheme I, scheme III; page 3210, column R, paragraph 4 - page 3212, column L, paragraph 3 * DOI: http://dx.doi.org/10.1021/jm00095a017 | [DX] - MUELLER B M ET AL, "ANTIBODY CONJUGATES WITH MORPHOLINODOXORUBICIN AND ACID-CLEAVABLE LINKERS", BIOCONJUGATE CHEMISTRY, (19900901), vol. 1, no. 5, pages 325 - 330, XP000174625 [DX] 1,32,33 * see scheme I and scheme II; page 327, column L, paragraph 1 - page 329, column L, paragraph 2 * DOI: http://dx.doi.org/10.1021/bc00005a005 | [DX] - F. ZUNINO ET AL., "Comparison of Antitumor Effects of Aunorubicin Covalently Linked to Poly-L-Amino Acid Carriers", EUROPEAN JOURNAL OF CANCER AND CLINICAL ONCOLOGY, (198403), vol. 20, no. 3, pages 421 - 425, XP000670366 [DX] 1,32,33 * page 421, column R, paragraph 3 - page 422, column L, paragraph 1 * * page 424, column L, paragraph 2 - page 425, column L, paragraph 1 * DOI: http://dx.doi.org/10.1016/0277-5379(84)90091-9 | [DA] - A.V. SCHALLY, "Hypothalamic Hormones: from neuroendocrinology to cancer therapy", ANTI-CANCER DRUGS, (199404), vol. 5, no. 2, pages 115 - 130, XP000670356 [DA] 1,2,32,33 * page 120, column R, paragraph 2 - page 121, column L, paragraph 1 * | [DA] - A. TROUET ET AL., "A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate. In vitro and in vivo studies", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, WASHINGTON US, (198201), vol. 79, pages 626 - 629, XP002029566 [DA] 1 * figure 1 * DOI: http://dx.doi.org/10.1073/pnas.79.2.626 |