Deutsch English Français

Contact

EP0815111

European procedure

Quick help

Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...

News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...

Extract from the Register of European Patents

EP About this file: EP0815111

EP0815111 - ANALOGUES OF N-ACETYLARDEEMIN, METHOD OF PREPARATION AND USES THEREOF [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 15.08.2008 Database last updated on 26.06.2024
Most recent event Tooltip	03.06.2011	Lapse of the patent in a contracting state New state(s): IT	published on 06.07.2011 [2011/27]
Applicant(s)	For all designated states The Trustees of Columbia University in the City of New York West 116th Street and Broadway New York New York 10027 / US
	For all designated states Sloan-Kettering Institute for Cancer Research 1275 York Avenue New York New York 10021 / US
	[N/P]
Former [2007/41]	For all designated states The Trustees of Columbia University in the City of New York West 116th Street and Broadway New York New York 10027 / US
	For all designated states Sloan-Kettering Institute For Cancer Research 1275 York Avenue New York New York 10021 / US
Former [1998/02]	For all designated states THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK West 116th Street and Broadway New York, New York 10027 / US
	For all designated states Sloan-Kettering Institute For Cancer Research 1275 York Avenue New York, New York 10021 / US
Inventor(s)	01 / DANISHEFSKY, Samuel 22 Brayton Street Englewood, NJ 07631 / US
	02 / DEPEW, Kristopher Apartment 2B 410 W. 24th Street New York, NY 10011 / US
	03 / MARSDEN, Stephen, P. Mitchell House Apartment 6 2a Oxford Road North London W4 4DT / GB
	04 / BORNMANN, William Apartment 9S 504 E. 63rd Street New York, NY 10021 / US
	05 / WOO, Jonathan, C., G. Apartment D 312 E. 66th Street New York, NY 10021 / US
	06 / CHOU, Ting-Chao 5 Daisy Way Paramus, NJ 07652 / US
	07 / SCHKERYANTZ, Jeffrey 526 English Lane Winthrop Harbor, IL 60048 / US
	08 / ZATORSKI, Andrej 303 E. 60th Street 33F New York, NY 10022 / US
	[1998/02]
Representative(s)	Crooks, Elizabeth Caroline Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL / GB
	[N/P]
Former [2005/01]	King, Elizabeth Caroline Kilburn & Strode 20 Red Lion Street London WC1R 4PJ / GB
Former [1998/02]	Sheard, Andrew Gregory Kilburn & Strode 30, John Street London WC1N 2DD / GB
Application number, filing date	96942827.5	15.11.1996
	[1998/02]
	WO1996US19086
Priority number, date	US19950006750	15.11.1995 Original published format: US 6750
	[1998/02]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9718215
	Date:	22.05.1997
	Language:	EN
	[1997/22]
	Type:	A1 Application with search report
	No.:	EP0815111
	Date:	07.01.1998
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 22.05.1997 takes the place of the publication of the European patent application.
	[1998/02]
	Type:	B1 Patent specification
	No.:	EP0815111
	Date:	10.10.2007
	Language:	EN
	[2007/41]
Search report(s)	International search report - published on:	US	22.05.1997
	(Supplementary) European search report - dispatched on:	EP	20.03.1998
Classification	IPC:	C07D487/22, C07D487/14, A61K31/505, A61K31/70, A61K31/495, A61K31/50	[2007/22]
	CPC:	C07D487/22 (EP,US); A61P35/02 (EP)
	Former IPC [1998/15]	C07D487/22, C07D487/14, A61K31/505, A61K31/70, A61K31/495, A61K31/50, // (C07D487/22, 241:00, 239:00, 209:00, 209:00),(C07D487/22, 241:00, 209:00, 209:00)
	Former IPC [1998/02]	C07D487/22, C07D487/14, A61K31/505, A61K31/70, A61K31/495
Designated contracting states	AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [1998/02]
Title	German:	ANALOGE VON N-ACETYLARDEEMIN, VERFAHREN ZUR HERSTELLUNG UND VERWENDUNG DIESER ANALOGEN	[1998/02]
	English:	ANALOGUES OF N-ACETYLARDEEMIN, METHOD OF PREPARATION AND USES THEREOF	[1998/02]
	French:	ANALOGUES DE LA N-ACETYLARDEEMINE, PROCEDES DE PREPARATION ET UTILISATION DESDITS ANALOGUES	[1998/02]
Entry into regional phase	14.08.1997	National basic fee paid
	14.08.1997	Search fee paid
	14.08.1997	Designation fee(s) paid
	20.11.1997	Examination fee paid
Examination procedure	20.11.1997	Examination requested [1998/04]
	23.12.1999	Despatch of a communication from the examining division (Time limit: M06)
	26.06.2000	Reply to a communication from the examining division
	08.11.2001	Despatch of a communication from the examining division (Time limit: M06)
	19.08.2002	Reply to a communication from the examining division
	17.02.2005	Despatch of a communication from the examining division (Time limit: M06)
	16.08.2005	Reply to a communication from the examining division
	31.08.2005	Despatch of a communication from the examining division (Time limit: M06)
	18.04.2006	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
	12.06.2006	Reply to a communication from the examining division
	22.09.2006	Despatch of a communication from the examining division (Time limit: M04)
	15.01.2007	Reply to a communication from the examining division
	07.05.2007	Communication of intention to grant the patent
	24.08.2007	Fee for grant paid
	24.08.2007	Fee for publishing/printing paid
Opposition(s)	11.07.2008	No opposition filed within time limit [2008/38]
Request for further processing for:	12.06.2006	Request for further processing filed
	14.06.2006	Full payment received (date of receipt of payment) Request granted
	07.08.2006	Decision despatched
	19.08.2002	Request for further processing filed
	20.08.2002	Full payment received (date of receipt of payment) Request granted
	06.09.2002	Decision despatched
Fees paid	Renewal fee
	10.11.1998	Renewal fee patent year 03
	12.11.1999	Renewal fee patent year 04
	20.11.2000	Renewal fee patent year 05
	22.11.2001	Renewal fee patent year 06
	25.11.2002	Renewal fee patent year 07
	21.11.2003	Renewal fee patent year 08
	22.11.2004	Renewal fee patent year 09
	29.11.2005	Renewal fee patent year 10
	27.11.2006	Renewal fee patent year 11
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	AT	10.10.2007
	BE	10.10.2007
	CH	10.10.2007
	DK	10.10.2007
	FI	10.10.2007
	LI	10.10.2007
	NL	10.10.2007
	IE	15.11.2007
	LU	15.11.2007
	IT	30.11.2007
	MC	30.11.2007
	GB	10.01.2008
	SE	10.01.2008
	DE	11.01.2008
	GR	11.01.2008
	ES	21.01.2008
	PT	10.03.2008
	[2011/27]
Former [2010/05]	AT	10.10.2007
	BE	10.10.2007
	CH	10.10.2007
	DK	10.10.2007
	FI	10.10.2007
	LI	10.10.2007
	NL	10.10.2007
	IE	15.11.2007
	LU	15.11.2007
	MC	30.11.2007
	GB	10.01.2008
	SE	10.01.2008
	DE	11.01.2008
	GR	11.01.2008
	ES	21.01.2008
	PT	10.03.2008
Former [2009/13]	AT	10.10.2007
	BE	10.10.2007
	CH	10.10.2007
	DK	10.10.2007
	FI	10.10.2007
	LI	10.10.2007
	NL	10.10.2007
	IE	15.11.2007
	MC	30.11.2007
	GB	10.01.2008
	SE	10.01.2008
	DE	11.01.2008
	GR	11.01.2008
	ES	21.01.2008
	PT	10.03.2008
Former [2009/04]	AT	10.10.2007
	BE	10.10.2007
	CH	10.10.2007
	DK	10.10.2007
	LI	10.10.2007
	NL	10.10.2007
	IE	15.11.2007
	MC	30.11.2007
	GB	10.01.2008
	SE	10.01.2008
	DE	11.01.2008
	ES	21.01.2008
	PT	10.03.2008
Former [2008/48]	AT	10.10.2007
	BE	10.10.2007
	CH	10.10.2007
	DK	10.10.2007
	LI	10.10.2007
	NL	10.10.2007
	IE	15.11.2007
	MC	30.11.2007
	SE	10.01.2008
	DE	11.01.2008
	ES	21.01.2008
	PT	10.03.2008
Former [2008/40]	AT	10.10.2007
	BE	10.10.2007
	CH	10.10.2007
	DK	10.10.2007
	LI	10.10.2007
	NL	10.10.2007
	MC	30.11.2007
	SE	10.01.2008
	DE	11.01.2008
	ES	21.01.2008
	PT	10.03.2008
Former [2008/35]	AT	10.10.2007
	CH	10.10.2007
	DK	10.10.2007
	LI	10.10.2007
	NL	10.10.2007
	MC	30.11.2007
	SE	10.01.2008
	DE	11.01.2008
	ES	21.01.2008
	PT	10.03.2008
Former [2008/29]	AT	10.10.2007
	CH	10.10.2007
	LI	10.10.2007
	NL	10.10.2007
	MC	30.11.2007
	SE	10.01.2008
	ES	21.01.2008
	PT	10.03.2008
Former [2008/24]	CH	10.10.2007
	LI	10.10.2007
	NL	10.10.2007
	SE	10.01.2008
	ES	21.01.2008
	PT	10.03.2008
Former [2008/23]	CH	10.10.2007
	LI	10.10.2007
	NL	10.10.2007
	SE	10.01.2008
	ES	21.01.2008
Documents cited:	Search	JPS58152487 [ ] (FUJISAWA PHARMACEUTICAL CO);
		JPS6041678 [ ] (FUJISAWA PHARMACEUTICAL CO);
		[A]WO9301718 (US AGRICULTURE [US], et al) [A] 11-17 * claim - *;
		[AD] - J.E. HOCHLOWSKI ET AL., JOURNAL OF ANTIBIOTICS., TOKYO JP, (1993), vol. 46, no. 3, pages 380 - 386, XP002055667 [AD] 1-10 * the whole document *
		[A] - CHEMICAL ABSTRACTS, (19840130), vol. 100, no. 5, Database accession no. 33257, XP002055668 [A] 11-17 * abstract *
		[A] - CHEMICAL ABSTRACTS, (19850916), vol. 103, no. 11, Database accession no. 87904, XP002055669 [A] 11-17 * CAS RN: 97565-53-2;97591-56-5;88901-66-0;88901-67 -1;88930-18-1;94607-93-9;97565-55-4;97565- 56-5;97591-57-6,97591-58-7,94607-92-8 *
		[A] - CHEMICAL ABSTRACTS, (19850930), vol. 103, no. 13, Database accession no. 101553, XP002055670 [A] 11-17 * abstract *
		[ ] - I. LAWS ET AL., PHYTOCHEMISTRY, (1985), vol. 24, no. 6, pages 1395 - 1397
		[X] - CHEMICAL ABSTRACTS, (19880509), vol. 108, no. 19, Database accession no. 164470, XP002055671 [X] 18 * abstract *
		[ ] - R.P. HODGE ET AL., J. NAT. PROD., (1988), vol. 51, no. 1, pages 66 - 73
	International search	[X]US5284947 (KADAM SUNIL K [US], et al);
		[X]US5338845 (BARROW COLIN J [US], et al)
		[X] - JOURNAL OF ANTIBIOTICS, March 1993, Vol. 46, No. 3, KARWOWSKI et al., "5N-Acetylardeemin, A Novel Heterocyclic Compound Which Reverses Multipe Drug Resistance in Tumor Cells", pages 374-379.
		[X] - JOURNAL OF AMERICAN CHEMICAL SOCIETY, 30 November 1994, Vol. 116, MARSDEN et al., "Stereoselective Total Syntheses of Amauromine and 5-N-Acetylardeemin. A Concise Route to the Family of "Reverse-Prenylated" Hexahydropyrroloindole Alkaloids", pages 11143-11144.
		[A] - JOURNAL OF ANTIBIOTICS, February 1994, Vol. 47, No. 2, SHINOHARA et al., "Gypsetin, a New Inhibitor of Acyl-CoA: Cholesterol Acyltransferase Produced by Nannizzia Gypsea Var. Incurvata IFO 9228", pages 163-167.
		[A] - TETRAHEDRON LETTERS, 1984, Vol. 25, No. 41, TAKASE et al., "Structure of Amauromine, a New Alkaloid With Vasodilating Activity Produced by Amauroascus Sp", pages 4673-4676.
		[X] - TAKEUCHI CHEMICAL AND PHARMACEUTICAL BULLETIN, November 1989, Vol. 37, No. 11, ARAI et al., "Structures of Fructigenines A and B, New Alkaloids Isolated from Penicillium Fructigenum", pages 2937-2939.

The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.

Legal notice
Terms of use
24.1.24; 34p