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Extract from the Register of European Patents

EP About this file: EP0962525

EP0962525 - PHAGE BONDED TO NUCLEAR LOCATION SIGNAL [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  08.09.2006
Database last updated on 15.06.2024
Most recent event   Tooltip21.10.2011Lapse of the patent in a contracting statepublished on 23.11.2011  [2011/47]
Applicant(s)For all designated states
Dnavec Research Inc.
25-11 Kannondai 1-chome Tsukuba-shi
Ibaraki 305 / JP
[N/P]
Former [2005/44]For all designated states
Dnavec Research Inc.
25-11 Kannondai 1-chome Tsukuba-shi
Ibaraki 305 / JP
Former [1999/49]For all designated states
Dnavec Research Inc.
25-11, Kannondai 1-chome, Tsukuba-shi
Ibaraki 305 / JP
Inventor(s)01 / NAKANISHI, Mahito
13-53-315, Tsurumi 3-chome, Tsurumi-ku
Osaka-shi, Osaka 538 / JP
02 / NAGOSHI, Emi
7-11, Akasakadai 3-chome
Sakai-shi, Osaka 590-01 / JP
03 / AKUTA, Teruo
Dnavec Research Inc., 25-11, Kannondai 1-chome
Tsukuba-shi, Ibaraki 305 / JP
04 / TAKEDA, Katsuo
Dnavec Research Inc., 25-11, Kannondai 1-chome
Tsukuba-shi, Ibaraki 305 / JP
05 / HASEGAWA, Mamoru
Dnavec Research Inc., 25-11, Kannondai 1-chome
Tsukuba-shi, Ibaraki 305 / JP
[1999/49]
Representative(s)Becker Kurig & Partner Patentanwälte mbB
Bavariastraße 7
80336 München / DE
[N/P]
Former [2000/05]Becker Kurig Straus
Patentanwälte Bavariastrasse 7
80336 München / DE
Former [1999/49]Straus, Alexander, Dr., et al
Patentanwälte Becker, Kurig, Straus Bavariastrasse 7
80336 München / DE
Application number, filing date96943332.527.12.1996
[1999/49]
WO1996JP03861
Priority number, dateJP1996022778709.08.1996         Original published format: JP 22778796
[1999/49]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9806828
Date:19.02.1998
Language:EN
[1998/07]
Type: A1 Application with search report 
No.:EP0962525
Date:08.12.1999
Language:EN
The application published by WIPO in one of the EPO official languages on 19.02.1998 takes the place of the publication of the European patent application.
[1999/49]
Type: B1 Patent specification 
No.:EP0962525
Date:02.11.2005
Language:EN
[2005/44]
Search report(s)International search report - published on:JP19.02.1998
(Supplementary) European search report - dispatched on:EP23.10.2001
ClassificationIPC:C12N7/01, C12N15/87, C07K19/00, C12N1/21, C12N5/10, C12N15/85, // (C12N7/01, C12R1:92)
[2001/48]
CPC:
C12N15/1037 (EP,US); C12N7/00 (KR); C12N15/85 (EP,US);
C12N15/86 (EP,US); C12N15/87 (EP,US); C12N2795/10343 (EP,US)
Former IPC [1999/49]C12N7/01, C12N15/87, C07K19/00, C12N1/21, C12N5/10, // (C12N7/01, C12R1:92)
Designated contracting statesAT,   CH,   DE,   DK,   ES,   FR,   GB,   IT,   LI,   NL,   SE [1999/49]
TitleGerman:PHAGE VERBUNDEN AN EIN NUKLEUS LOKALISIERUNGSSIGNAL[1999/49]
English:PHAGE BONDED TO NUCLEAR LOCATION SIGNAL[1999/49]
French:PHAGE LIE AU SIGNAL DE LOCALISATION NUCLEAIRE[1999/49]
Entry into regional phase03.02.1999Translation filed 
03.02.1999National basic fee paid 
03.02.1999Search fee paid 
03.02.1999Designation fee(s) paid 
03.02.1999Examination fee paid 
Examination procedure16.01.1998Request for preliminary examination filed
International Preliminary Examining Authority: JP
03.02.1999Examination requested  [1999/49]
05.11.2003Despatch of a communication from the examining division (Time limit: M06)
13.05.2004Reply to a communication from the examining division
22.09.2004Despatch of a communication from the examining division (Time limit: M04)
15.11.2004Reply to a communication from the examining division
09.05.2005Communication of intention to grant the patent
18.08.2005Fee for grant paid
18.08.2005Fee for publishing/printing paid
Opposition(s)03.08.2006No opposition filed within time limit [2006/41]
Fees paidRenewal fee
29.04.1999Renewal fee patent year 03
30.12.1999Renewal fee patent year 04
20.12.2000Renewal fee patent year 05
27.12.2001Renewal fee patent year 06
20.12.2002Renewal fee patent year 07
30.12.2003Renewal fee patent year 08
30.12.2004Renewal fee patent year 09
Penalty fee
Additional fee for renewal fee
01.01.199903   M06   Fee paid on   29.04.1999
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipES13.02.2006
[2011/47]
Documents cited:Search[E]WO9805344  (BRIGHAM & WOMENS HOSPITAL [US], et al) [E] 1-20* page 35, line 19 - line 25 *;
 [Y]  - TOMITA NARUYA ET AL, "A novel gene-transfer technique mediated by HVJ (Sendai virus), nuclear protein, and liposomes.", CANCER DETECTION AND PREVENTION, (1994), vol. 18, no. 6, ISSN 0361-090X, pages 485 - 491, XP001018485 [Y] 1-20 * the whole document *
 [Y]  - BARRY MICHAEL A ET AL, "Toward cell-targeting gene therapy vectors: Selection of cell-binding peptides from random peptide-presenting phage libraries", NATURE MEDICINE, NATURE PUBLISHING, CO, US, (1996), vol. 2, no. 3, ISSN 1078-8956, pages 299 - 305, XP002156129 [Y] 1-20 * the whole document * * abstract * * page 304, column 1, paragraph 2 *

DOI:   http://dx.doi.org/10.1038/nm0396-299
 [Y]  - STERNBERG N ET AL, "DISPLAY OF PEPTIDES AND PROTEINS ON THE SURFACE OF BACTERIOPHAGE LAMBDA", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, (199502), vol. 92, no. 5, ISSN 0027-8424, pages 1609 - 1613, XP000999450 [Y] 1-20 * the whole document * * page 1613, column 2, paragraph 2 *

DOI:   http://dx.doi.org/10.1073/pnas.92.5.1609
 [Y]  - MIKAWA Y G ET AL, "SURFACE DISPLAY OF PROTEINS ON BACTERIOPHAGE LAMBDA HEADS", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, (1996), vol. 262, no. 1, ISSN 0022-2836, pages 21 - 30, XP001008025 [Y] 1-13 * the whole document *

DOI:   http://dx.doi.org/10.1006/jmbi.1996.0495
 [Y]  - JESPERS L S ET AL, "SURFACE EXPRESSION AND LIGAND-BASED SELECTION OF CDNAS FUSED TO FILAMENTOUS PHAGE GENE VI", BIO/TECHNOLOGY, NATURE PUBLISHING CO. NEW YORK, US, (19950401), vol. 13, ISSN 0733-222X, pages 378 - 382, XP000652425 [Y] 1,2,6,7,10-13 * the whole document *

DOI:   http://dx.doi.org/10.1038/nbt0495-378
 [A]  - PERALES J C ET AL, "An evaluation of receptor-mediated gene transfer using synthetic DNA-ligand complexes", EUROPEAN JOURNAL OF BIOCHEMISTRY, BERLIN, DE, (199412), vol. 226, no. 2, ISSN 0014-2956, pages 255 - 266, XP002099634 [A] 1-20 * the whole document * * figure 1 * * page 262, column 2, paragraph 2 *

DOI:   http://dx.doi.org/10.1111/j.1432-1033.1994.tb20049.x
 [A]  - RUSSELL S J, "PEPTIDE-DISPLAYING PHAGES FOR TARGETED GENE DELIVERY?", NATURE MEDICINE, NATURE PUBLISHING, CO, US, (19960301), vol. 2, no. 3, ISSN 1078-8956, pages 276 - 277, XP002910199 [A] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.1038/nm0396-276
 [A]  - NAKANISHI AKIRA ET AL, "Association with capsid proteins promotes nuclear targeting of simian virus 40 DNA.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, 1996, (1996), vol. 93, no. 1, ISSN 0027-8424, pages 96 - 100, XP002178496 [A] 1-20 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.93.1.96
 [A]  - BOULIKAS T, "Nuclear localization signals (NLS)", CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION, BEGELL HOUSE, NEW YORK, NY, US, (1993), vol. 3, no. 3, ISSN 1045-4403, pages 193 - 227, XP002113642 [A] 1-20 * the whole document *
 [A]  - LEDLEY F D, "NONVIRAL GENE THERAPY: THE PROMISE OF GENES AS PHARMACEUTICAL PRODUCTS", HUMAN GENE THERAPY, XX, XX, (199509), vol. 6, no. 9, ISSN 1043-0342, pages 1129 - 1144, XP001007686 [A] 1-20 * the whole document *
International search[A]JPH07508168  ;
 [A]  - GREBER U F, KASAMATSU H, "NUCLEAR TARGETING OF SV40 AND ADENOVIRUS", TRENDS IN CELL BIOLOGY., ELSEVIER SCIENCE LTD., XX, XX, (19960501), vol. 06, no. 05, doi:10.1016/0962-8924(96)10016-7, ISSN 0962-8924, pages 189 - 195, XP001008034

DOI:   http://dx.doi.org/10.1016/0962-8924(96)10016-7
 [A]  - ZABNER ET AL, "CELLULAR AND MOLECULAR BARRIERS TO GENE TRANSFER BY A CATIONIC LIPID", Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, US, US, (19950101), vol. 270, no. 32, doi:10.1074/jbc.270.32.18997, ISSN 0021-9258, pages 18997 - 19007, XP002080031

DOI:   http://dx.doi.org/10.1074/jbc.270.32.18997
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.