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EP About this file: EP0888341

EP0888341 - NOVEL SULPHUR DERIVATIVES COMPRISING AN AMIDE BOND, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 06.10.2006 Database last updated on 22.08.2024
Most recent event Tooltip	06.10.2006	No opposition filed within time limit	published on 08.11.2006 [2006/45]
Applicant(s)	For all designated states Aventis Pharma S.A. 20, avenue Raymond Aron 92160 Antony / FR
	For all designated states INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) 101, rue de Tolbiac 75654 Paris Cédex 13 / FR
	[2005/48]
Former [2001/14]	For all designated states Aventis Pharma S.A. 20, avenue Raymond Aron 92160 Antony / FR
	For all designated states INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) 101, rue de Tolbiac 75654 Paris Cédex 13 / FR
Former [1999/01]	For all designated states HOECHST MARION ROUSSEL 1, Terrasse Bellini 92800 Puteaux / FR
	For all designated states INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) 101, rue de Tolbiac 75654 Paris Cédex 13 / FR
Inventor(s)	01 / DEPREZ, Pierre 4, rue Albert-de-Dion F-94320 Thiais / FR
	02 / DUMAS, Jacques 10, rue de la Pelouse F-93360 Neuilly-Plaisance / FR
	03 / FOURNIE-ZALUSKI, Marie-Claude 16, avenue de Bouvines F-75011 Paris / FR
	04 / GUILLAUME, Jacques 52, boulevard de la République F-93190 Livry-Gargan / FR
	05 / ROQUES, Bernard, Pierre 12, rue Eugène-Delacroix F-94440 Saint-Maurice / FR
	[1999/01]
Representative(s)	(deleted)
	[2005/02]
Former [2004/29]	Grosset-Fournier, Chantal Catherine, et al Grosset-Fournier & Demachy, 54,rue Saint-Lazare 75009 Paris / FR
Former [2001/14]	(deleted)
Former [1999/01]	Vieillefosse, Jean-Claude Hoechst Marion Roussel Département des Brevets 102, Route de Noisy 93235 Romainville Cedex / FR
Application number, filing date	97907157.8	03.03.1997
	[1999/01]
	WO1997FR00367
Priority number, date	FR19960002672	04.03.1996 Original published format: FR 9602672
	[1999/01]
Filing language	FR
Procedural language	FR
Publication	Type:	A1 Application with search report
	No.:	WO9732874
	Date:	12.09.1997
	Language:	FR
	[1997/39]
	Type:	A1 Application with search report
	No.:	EP0888341
	Date:	07.01.1999
	Language:	FR
	The application published by WIPO in one of the EPO official languages on 12.09.1997 takes the place of the publication of the European patent application.
	[1999/01]
	Type:	B1 Patent specification
	No.:	EP0888341
	Date:	30.11.2005
	Language:	FR
	[2005/48]
Search report(s)	International search report - published on:	EP	12.09.1997
Classification	IPC:	C07D405/12, C07D333/24, C07D257/04, C07C323/60, C07D209/18, A61K31/405, A61K31/195	[1999/01]
	CPC:	C07D257/04 (EP,KR,US); A61P13/00 (EP); A61P13/12 (EP); A61P43/00 (EP); A61P9/00 (EP); C07C323/60 (EP,KR,US); (+) C07D209/18 (EP,KR,US); C07D333/24 (EP,KR,US); C07D405/12 (EP,KR,US) (-)
Designated contracting states	AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, NL, PT, SE [1999/01]
Title	German:	EINE AMIDGRUPPE TRAGENDE SCHWEFELHALTIGE VERBINDUNGEN, VERFAHREN ZU IHRER HERSTELLUNG, DEREN VERWENDUNG IN MEDIKAMENTEN UND SIE ENTHALTENDE PHARMAZEUTISCHE ZUBEREITUNGEN	[1999/01]
	English:	NOVEL SULPHUR DERIVATIVES COMPRISING AN AMIDE BOND, METHOD FOR PREPARING SAME, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH DERIVATIVES	[1999/01]
	French:	NOUVEAUX DERIVES SOUFRES COMPORTANT UNE LIAISON AMIDE, LEUR PROCEDE DE PREPARATION, LEUR APPLICATION A TITRE DE MEDICAMENTS ET LES COMPOSITIONS PHARMACEUTIQUES LES RENFERMANT	[1999/01]
Entry into regional phase	05.10.1998	National basic fee paid
	05.10.1998	Designation fee(s) paid
	05.10.1998	Examination fee paid
Examination procedure	18.09.1997	Request for preliminary examination filed International Preliminary Examining Authority: EP
	05.10.1998	Examination requested [1999/01]
	06.12.2000	Despatch of a communication from the examining division (Time limit: M04)
	17.04.2001	Reply to a communication from the examining division
	29.11.2001	Despatch of a communication from the examining division (Time limit: M06)
	31.05.2002	Reply to a communication from the examining division
	25.09.2003	Despatch of a communication from the examining division (Time limit: M06)
	13.04.2004	Reply to a communication from the examining division
	22.04.2004	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
	02.07.2004	Despatch of a communication from the examining division (Time limit: M06)
	27.12.2004	Reply to a communication from the examining division
	17.05.2005	Communication of intention to grant the patent
	27.09.2005	Fee for grant paid
	27.09.2005	Fee for publishing/printing paid
Opposition(s)	31.08.2006	No opposition filed within time limit [2006/45]
Request for further processing for:	03.05.2004	Request for further processing filed
	03.05.2004	Full payment received (date of receipt of payment) Request granted
	14.05.2004	Decision despatched
Fees paid	Renewal fee
	31.03.1999	Renewal fee patent year 03
	31.03.2000	Renewal fee patent year 04
	02.04.2001	Renewal fee patent year 05
	02.04.2002	Renewal fee patent year 06
	31.03.2003	Renewal fee patent year 07
	31.03.2004	Renewal fee patent year 08
	31.03.2005	Renewal fee patent year 09
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited in	International search	[A]DE2349707 (SANTEN PHARMACEUTICAL CO LTD ) [A] 1-10 * example 1; claim - *;
		[X]US4053651 (ONDETTI MIGUEL ANGEL, et al) [X] 1-10 * abstract *;
		[X] - J.L. BALWIERCZAK ET AL., "Effects of metalloproteinase inhibitors on smooth muscle endothelin-converting enzyme activity", CHEMICAL ABSTRACTS, (19950508), vol. 122, no. 19, Database accession no. 230128, XP002019777 [X] 1-10 * abstract *
		[ ] - BIOCHEM. PHARMACOL., (1995), vol. 49, no. 3, pages 291 - 296
		[X] - M.-C. FOURNI -ZALUSKI ET AL., "New Dual Inhibitors of Neutral Endopeptidase and Angiotensin-Converting Enzyme:...", JOURNAL OF MEDICINAL CHEMISTRY, WASHINGTON US, (1994), vol. 37, no. 8, pages 1070 - 1083, XP002019771 [X] 1-10 * abstract * DOI: http://dx.doi.org/10.1021/jm00034a005
		[X] - T. KOMORI ET AL., "Sulfur-Containing Acylamino Acids. I. ...", CHEMICAL AND PHARMACEUTICAL BULLETIN, TOKYO JP, (1987), vol. 35, no. 6, pages 2382 - 2387, XP002019773 [X] 1-10 * abstract *
		[X] - T. KOMORI ET AL., "Sulfur-Containing Acylamino Acids. II. ...", CHEMICAL AND PHARMACEUTICAL BULLETIN, TOKYO JP, (1987), vol. 35, no. 6, pages 2388 - 2393, XP002019774 [X] 1-10 * abstract *
		[X] - M. OYA ET AL., "Thiol Compounds. I. Synthesis and Antihypertensive Activity of Mercaptoacylamino Acids", CHEMICAL AND PHARMACEUTICAL BULLETIN, TOKYO JP, (1981), vol. 29, no. 1, pages 63 - 70, XP002019775 [X] 1-10 * the whole document *
		[A] - M.-C. FOURNI -ZALUSKI ET AL., ""Mixed Inhibitor-Prodrug" as a New Approach toward Systematically Active Inhibitors of Enkephalin-Degrading Enzyme", JOURNAL OF MEDICINAL CHEMISTRY, WASHINGTON US, (1992), vol. 35, no. 13, pages 2473 - 2481, XP002019768 [A] 1-10 * abstract * DOI: http://dx.doi.org/10.1021/jm00091a016
		[A] - M.-C. FOURNI -ZALUSKI ET AL., "1H-NMR Configurational Correlation for Retro-Inverso Dipeptides: Application to the Determination of the Absolute Configuration of the "Enkephalinase" Inhibitors. ....", JOURNAL OF MEDICINAL CHEMISTRY, WASHINGTON US, (1986), vol. 29, no. 5, pages 751 - 757, XP002019769 [A] 1-10 * abstract * DOI: http://dx.doi.org/10.1021/jm00155a027
		[A] - M.-C. FOURNI -ZALUSKI ET AL., "New Bidentates as Full Inhibitors of Enkephalin-Degrading Enzymes: Synthesis and Analgesic Properties", JOURNAL OF MEDICINAL CHEMISTRY, WASHINGTON US, (1985), vol. 28, no. 9, pages 1158 - 1169, XP002019770 [A] 1-10 * abstract * DOI: http://dx.doi.org/10.1021/jm00147a007
		[A] - B.R. NEUSTADT ET AL., "Mercaptoacyl Amino Acid Inhibitors of Atriopeptidase. ...", JOURNAL OF MEDICINAL CHEMISTRY, WASHINGTON US, (1994), vol. 37, no. 15, pages 2461 - 2476, XP002019772 [A] 1-10 * abstract * DOI: http://dx.doi.org/10.1021/jm00041a026
		[A] - D.A. EVANS ET AL., "Asymmetric Synthesis of the Enkephalinase Inhibitor Thiorphan", JOURNAL OF ORGANIC CHEMISTRY, EASTON US, (1985), vol. 50, no. 11, pages 1830 - 1835, XP002019776 [A] 1-10 * abstract * DOI: http://dx.doi.org/10.1021/jo00211a008
		[PX] - K. BARNES ET AL., "Metallopeptidase inhibitors induce an up-regulation of endothelin-converting enzyme levels and its redistribution from the plasma membrane to an intracellular compartment", CHEMICAL ABSTRACTS, (19960729), vol. 125, no. 5, Database accession no. 54282, XP002019778 [PX] 1-10 * abstract *
		[ ] - J. CELL SCI., (1996), vol. 109, no. 5, pages 919 - 928

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