EP0918797 - HUMANIZED IMMUNOGLOBULIN REACTIVE WITH ALPHA4BETA7 INTEGRIN [Right-click to bookmark this link] | |||
Former [1999/22] | HUMANIZED IMMUNOGLOBULIN REACTIVE WITH $g(a)4$g(b)7 INTEGRIN | ||
[1999/52] | Status | Patent maintained as amended Status updated on 21.08.2015 Database last updated on 30.10.2024 | Most recent event Tooltip | 21.08.2015 | Patent maintained (B2 publication) | published on 23.09.2015 [2015/39] | Applicant(s) | For all designated states MILLENNIUM PHARMACEUTICALS, INC. 75 Sidney Street Cambridge Massachusetts 02139 / US | [2006/13] |
Former [2000/46] | For all designated states Millennium Pharmaceuticals, Inc. 75 Sidney Street Cambridge, Massachusetts 02139 / US | ||
Former [2000/44] | For all designated states MILLENIUM PHARMACEUTICALS, INC. 640 Memorial Drive Cambridge, MA 02139 / US | ||
Former [1999/22] | For all designated states Leukosite, Inc. 215 First Street Cambridge, MA 02142 / US | Inventor(s) | 01 /
PONATH, Paul, D. 45 Upton, No. 3 Boston, MA 02118 / US | 02 /
RINGLER, Douglas, J. 382 Ocean Avenue, No. 1008 Revere, MA 02151 / US | 03 /
JONES, S., Tarran 1 Christchurch Crescent Radlett Hertfordshire WD7 8AG / GB | 04 /
NEWMAN, Walter 3 Durham Street, No. 3 Boston, MA 02115 / US | 05 /
SALDANHA, José 22A Lincoln Way Enfield Middlesex EN1 1TE / GB | 06 /
BENDIG, Mary, M. 26 Gresham Avenue London N20 0XL / GB | [2015/39] |
Former [1999/22] | 01 /
PONATH, Paul, D. 45 Upton, No. 3 Boston, MA 02118 / US | ||
02 /
RINGLER, Douglas, J. 382 Ocean Avenue, No. 1008 Revere, MA 02151 / US | |||
03 /
JONES, S., Tarran 1 Christchurch Crescent, Radlett Hertfordshire WD7 8AG / GB | |||
04 /
NEWMAN, Walter 3 Durham Street, No. 3 Boston, MA 02115 / US | |||
05 /
SALDANHA, José 22A Lincoln Way, Enfield Middlesex EN1 1TE / GB | |||
06 /
BENDIG, Mary, M. 26 Gresham Avenue London N20 0XL / GB | Representative(s) | Dossmann, Gérard Casalonga & Partners Bayerstrasse 71-73 80335 München / DE | [2015/39] |
Former [2009/30] | Dossmann, Gérard Bureau D.A. Casalonga & Josse Bayerstrasse 71/73 80335 München / DE | ||
Former [2009/08] | Dossmann, Gérard Bureau Casalonga & Josse Bayerstrasse 71/73 80335 München / DE | ||
Former [1999/22] | Price, Vincent Andrew, et al FRY HEATH & SPENCE The Old College 53 High Street Horley Surrey RH6 7BN / GB | Application number, filing date | 97937148.1 | 06.08.1997 | [1999/22] | WO1997US13884 | Priority number, date | US19960700737 | 15.08.1996 Original published format: US 700737 | [1999/22] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO9806248 | Date: | 19.02.1998 | Language: | EN | [1998/07] | Type: | A2 Application without search report | No.: | EP0918797 | Date: | 02.06.1999 | Language: | EN | The application published by WIPO in one of the EPO official languages on 19.02.1998 takes the place of the publication of the European patent application. | [1999/22] | Type: | B1 Patent specification | No.: | EP0918797 | Date: | 29.03.2006 | Language: | EN | [2006/13] | Type: | B2 New European patent specification | No.: | EP0918797 | Date: | 23.09.2015 | Language: | EN | [2015/39] | Search report(s) | International search report - published on: | EP | 07.05.1998 | Classification | IPC: | C07K16/28, C07K14/705 | [1999/22] | CPC: |
C07K16/2839 (EP,US);
A61P1/00 (EP);
A61P1/04 (EP);
A61P29/00 (EP);
A61P37/00 (EP);
C07K14/70503 (EP,US);
| Designated contracting states | AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2015/39] |
Former [1999/22] | AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE | Extension states | AL | 08.03.1999 | LT | 08.03.1999 | LV | 08.03.1999 | RO | 08.03.1999 | SI | 08.03.1999 | Title | German: | HUMANISIERTES IMMUNGLOBULIN GEGEN DEN ALPHA4BETA7-INTEGRIN | [2003/22] | English: | HUMANIZED IMMUNOGLOBULIN REACTIVE WITH ALPHA4BETA7 INTEGRIN | [2003/22] | French: | IMMUNOGLOBINE HUMANISE REAGISSANT AVEC L'INTEGRINE ALPHA4BETA7 | [2003/22] |
Former [1999/22] | HUMANISIERTES IMMUNGLOBULIN GEGEN DEN ALPHA4BETA7-INTEGRIN | ||
Former [1999/22] | HUMANIZED IMMUNOGLOBULIN REACTIVE WITH $g(a)4$g(b)7 INTEGRIN | ||
Former [1999/22] | IMMUNOGLOBINE HUMANISE REAGISSANT AVEC L'INTEGRINE $g(a)4$g(b)7 | Entry into regional phase | 08.03.1999 | National basic fee paid | 08.03.1999 | Designation fee(s) paid | 08.03.1999 | Examination fee paid | Examination procedure | 27.02.1998 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 08.03.1999 | Examination requested [1999/22] | 06.02.2003 | Amendment by applicant (claims and/or description) | 24.04.2003 | Communication of intention to grant the patent | 11.12.2003 | Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time | 13.02.2004 | Fee for grant paid | 13.02.2004 | Fee for publishing/printing paid | 16.03.2004 | Despatch of a communication from the examining division (Time limit: M04) | 29.06.2004 | Reply to a communication from the examining division | 09.09.2004 | Despatch of a communication from the examining division (Time limit: M02) | 08.11.2004 | Reply to a communication from the examining division | Divisional application(s) | EP06006108.2 / EP1710314 | EP16168412.1 | Opposition(s) | Opponent(s) | 01
22.12.2006
02.02.2007
ADMISSIBLE ELAN PHARMACEUTICALS INC. 800 Gateway Blvd, South San Francisco CALIFORNIA 94080 / US Opponents representative Mercer, Christopher Paul Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB | 02
29.12.2006
02.02.2007
ADMISSIBLE Amgen, Inc One Amgen Center Drive Thousand Oaks CA 91320 / US Opponents representative Grünecker Patent- und Rechtsanwälte PartG mbB Leopoldstraße 4 80802 München / DE | [2015/22] |
Former [2009/51] | |||
Opponent(s) | 01
22.12.2006
02.02.2007
ADMISSIBLE ELAN PHARMACEUTICALS INC. 800 Gateway Blvd, South San Francisco CALIFORNIA 94080 / US Opponents representative Mercer, Christopher Paul Carpmaels & Ransford 43-45 Bloomsbury Square London WC1A 2RA / GB | ||
02
29.12.2006
02.02.2007
ADMISSIBLE Amgen, Inc One Amgen Center Drive Thousand Oaks CA 91320 / US Opponents representative Vogelsang-Wenke, Heike Grünecker Kinkeldey Stockmair & Schwanhäusser Anwaltssozietät Leopoldstrasse 4 80802 München / DE | |||
Former [2007/07] | |||
Opponent(s) | 01
22.12.2006
ELAN PHARMACEUTICALS INC. 800 Gateway Blvd, South San Francisco CALIFORNIA 94080 / US Opponents representative Mercer, Christopher Paul Carpmaels & Ransford, 43-45 Bloomsbury Square London WC1A 2RA / GB | ||
02
29.12.2006
Amgen, Inc One Amgen Center Drive Thousand Oaks CA 91320 / US Opponents representative Vogelsang-Wenke, Heike Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät Maximilianstrasse 58 80538 München / DE | |||
Former [2007/05] | |||
Opponent(s) | 01
22.12.2006
ELAN PHARMACEUTICALS INC. 800 Gateway Blvd, South San Francisco CALIFORNIA 94080 / US Opponents representative Mercer, Christopher Paul Carpmaels & Ransford, 43-45 Bloomsbury Square London WC1A 2RA / GB | 09.02.2007 | Invitation to proprietor to file observations on the notice of opposition | 08.08.2007 | Reply of patent proprietor to notice(s) of opposition | 15.12.2009 | Date of oral proceedings | 26.04.2010 | Despatch of interlocutory decision in opposition | 26.04.2010 | Despatch of minutes of oral proceedings | 02.04.2015 | Legal effect of interlocutory decision in opposition | 11.05.2015 | Despatch of communication that the patent will be maintained as amended | 13.08.2015 | Fee for printing new specification paid | Appeal following opposition | 06.07.2010 | Appeal received No. T1521/10 | 23.08.2010 | Statement of grounds filed | 02.04.2015 | Result of appeal procedure: appeal of the proprietor withdrawn | Request for further processing for: | 13.02.2004 | Request for further processing filed | 13.02.2004 | Full payment received (date of receipt of payment) Request granted | 03.03.2004 | Decision despatched | Fees paid | Renewal fee | 28.07.1999 | Renewal fee patent year 03 | 21.07.2000 | Renewal fee patent year 04 | 31.07.2001 | Renewal fee patent year 05 | 14.08.2002 | Renewal fee patent year 06 | 13.08.2003 | Renewal fee patent year 07 | 12.08.2004 | Renewal fee patent year 08 | 19.08.2005 | Renewal fee patent year 09 |
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Former [2010/05] | IT | 06.08.2008 | Cited in | International search | [A]JPH06303990 ; | [A]WO9417828 (BIOGEN INC [US], et al) [A] 1-51 * page 15, line 4 - page 17, line 25 * * examples 1-4 * * claim - *; | [A]WO9519790 (ATHENA NEUROSCIENCES INC [US], et al) [A] 1-51 * the whole document *; | [PA]WO9718838 (ATHENA NEUROSCIENCES INC [US], et al) [PA] 1-51* the whole document *; | [DA] - A. LAZAROVITS ET AL., "Differential expression in rheumatoid synovium and synovial fluid of alpha4beta7 integrin.", THE JOURNAL OF IMMUNOLOGY, BALTIMORE, MD, USA, (19931201), vol. 151, no. 11, pages 6482 - 6489, XP002048548 [DA] 1-40 * the whole document * | [DA] - C. KETTLEBOROUGH ET AL., "Humanization of a mouse monoclonal antibody by CDR-grafting: the importance of framework residues on loop conformation.", PROTEIN ENGINEERING, OXFORD, GB, (199110), vol. 4, no. 7, pages 773 - 783, XP002048549 [DA] 1-40 * the whole document * | [DA] - T. SCHWEIGHOFFER ET AL., "Selective expression of integrin alpha4beta7 on a subset of human CD4+ memory T cells with hallmarks of gut-trophism.", THE JOURNAL OF IMMUNOLOGY, BALTIMORE, MD, USA, (19930715), vol. 151, no. 2, pages 717 - 729, XP002048550 [DA] 1-40 * the whole document * | [A] - M. BRISKIN ET AL., "Structural requirements for mucosal vascular addressin binding to its lymphocyte receptor alpha4beta7.", THE JOURNAL OF IMMUNOLOGY, BALTIMORE, MD, USA, (19960115), vol. 156, no. 2, pages 719 - 726, XP002048551 [A] 1-51 * abstract * | [A] - DATABASE WPI, 1, Derwent World Patents Index, vol. 95, no. 03, Database accession no. 95-018280, XP002048552 & JPH06303990 A 19941101 (KANEBO LTD.) [A] 1-40 * abstract * | Opposition | US5530101 | - A. I. LAZAROVITS ET AL., "Lymphocyte activation antigens", THE JOURNAL OF IMMUNOLOGY, (19841004), vol. 133, no. 4, pages 1857 - 1862 | - D. G. WOODSIDE ET AL., "Specific Inhibition of T Lymphocyte Coactivation by Triggering Integrin ß¹ Reveals Convergence of ß¹, ß², and ß7 Signaling Pathways¹", THE JOURNAL OF IMMUNOLOGY, (1996), vol. 157, no. 2, pages 700 - 706 | - R. VAN DER VOORT ET AL., "Paracrine Regulation of Germinal Center B Cell Adhesion through the c-Met-Hepatocyte Growth Factor/Scatter Factor Pathway", J. EXP. MED., (19970616), vol. 185, no. 12, pages 2121 - 2131 | - L. S. ROTT ET AL., "Expression of Mucosal Homing Receptor x4ß7 by Circualting CD4+ Cells with Memoryfor Intestinal Rotavirus", THE JOURNAL OF CLINICAL INVESTIGATION, (19970905), vol. 100, no. 5, pages 1204 - 1208 | - T. KENT ET AL., "Integrin x4ß7 Co-Stimulation of Human Peripheral Blood T Cell Proliferation", CELL ADHESION AND COMMUNICATION, (1994), vol. 2, pages 539 - 547 |