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EP About this file: EP1007062

EP1007062 - THERAPEUTIC USE OF HEMOGLOBIN TO TREAT HEAD INJURY [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 27.08.2004 Database last updated on 31.08.2024
Most recent event Tooltip	27.08.2004	Application deemed to be withdrawn	published on 13.10.2004 [2004/42]
Applicant(s)	For all designated states Baxter International Inc. One Baxter Parkway Deerfield, IL 60015 / US
	[N/P]
Former [2000/24]	For all designated states BAXTER INTERNATIONAL INC. One Baxter Parkway Deerfield, IL 60015 / US
Inventor(s)	01 / BURHOP, Kenneth, E. 1230 Regent Drive Mundelein, IL 60060 / US
	02 / SHACKFORD, Steven, R. 10 Westview Lane Shelburne, VT 05482 / US
	[2000/24]
Representative(s)	Bassett, Richard Simon, et al Potter Clarkson LLP The Belgrave Centre Talbot Street Nottingham NG1 5GG / GB
	[N/P]
Former [2004/15]	Bassett, Richard Simon, et al Eric Potter Clarkson, Park View House, 58 The Ropewalk Nottingham NG1 5DD / GB
Former [2000/24]	Baker, Colin John, et al Eric Potter Clarkson Park View House 58 The Ropewalk Nottingham NG1 5DD / GB
Application number, filing date	97945406.3	30.09.1997
	[2000/24]
	WO1997US17673
Priority number, date	US19960734296	21.10.1996 Original published format: US 734296
	[2000/24]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9817289
	Date:	30.04.1998
	Language:	EN
	[1998/17]
	Type:	A1 Application with search report
	No.:	EP1007062
	Date:	14.06.2000
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 30.04.1998 takes the place of the publication of the European patent application.
	[2000/24]
Search report(s)	International search report - published on:	US	30.04.1998
	(Supplementary) European search report - dispatched on:	EP	20.08.2002
Classification	IPC:	A61K35/14, A61K38/42, A61P43/00	[2002/39]
	CPC:	A61K38/42 (EP,US); A61P17/00 (EP); A61P25/00 (EP); A61P31/00 (EP); A61P43/00 (EP)
	Former IPC [2000/24]	A61K35/14, A61K38/16
Designated contracting states	DE, FR, GB [2000/24]
Title	German:	THERAPEUTISCHE VERWENDUNG VON HÄMOGLOBIN ZUR BEHANDLUNG VON KOPFVERLETZUNGEN	[2000/24]
	English:	THERAPEUTIC USE OF HEMOGLOBIN TO TREAT HEAD INJURY	[2000/24]
	French:	UTILISATION THERAPEUTIQUE DE L'HEMOGLOBINE DANS LE TRAITEMENT DES LESIONS CEREBRALES	[2000/24]
Entry into regional phase	15.04.1999	National basic fee paid
	15.04.1999	Search fee paid
	15.04.1999	Designation fee(s) paid
	15.04.1999	Examination fee paid
Examination procedure	28.04.1998	Request for preliminary examination filed International Preliminary Examining Authority: US
	15.04.1999	Examination requested [2000/24]
	30.09.2003	Despatch of a communication from the examining division (Time limit: M06)
	14.04.2004	Application deemed to be withdrawn, date of legal effect [2004/42]
	14.05.2004	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2004/42]
Fees paid	Renewal fee
	03.09.1999	Renewal fee patent year 03
	04.09.2000	Renewal fee patent year 04
	24.09.2001	Renewal fee patent year 05
	23.09.2002	Renewal fee patent year 06
	24.09.2003	Renewal fee patent year 07
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[X]WO9632130 (BAXTER INT [US]) [X] 1-25 cf. abstract, page 2, lines 11-21, line 35 bridging with page 3, lines 1-18;
		[X] - COLE D J ET AL, "FOCAL CEREBRAL ISCHEMIA IN RATS EFFECT OF HYPERVOLEMIC HEMODILUTION WITH DIASPIRIN CROSS-LINKED HEMOGLOBIN VERSUS ALBUMIN ON BRAIN INJURY AND EDEMA", ANESTHESIOLOGY, AMERICAN SOCIETY OF ANESTHESIOLOGISTS, PHILADELPHIA, PA,, US, (199302), vol. 78, no. 2, ISSN 0003-3022, pages 335 - 342, XP001041008 [X] 1-25 cf. abstract, page 341, left-sided col. 2nd para.
		[X] - COLE D J ET AL, "DIASPIRIN CROSSLINKED HEMOGLOBIN (DCLHB): EFFECT OF HEMODILUTION DURING FOCAL CEREBRAL ISCHEMIA IN RATS", ARTIFICIAL CELLS, BLOOD SUBSTITUTES, AND IMMOBILIZATION BIOTECHNOLOGY, MARCEL DEKKER INC, US, (1994), vol. 22, no. 3, ISSN 1073-1199, pages 813 - 818, XP002066050 [X] 1-25 cf. abstract, page 814, para. 2, page 817, last para. DOI: http://dx.doi.org/10.3109/10731199409117915
		[X] - J.E. CHAPPELL ET AL., "Diaspirin cross-linked hemoglobin resuscitation improves cerebral perfusion after head injury and shock", JOURNAL OF TRAUMA, (1996), vol. 41, no. 5, pages 781 - 788, XP001095507 [X] 1-25 cf. abstract, page 787, left-sided col., last para. DOI: http://dx.doi.org/10.1097/00005373-199611000-00003
		[X] - D.J. COLE, J.C. DRUMMOND ET AL., "Effect of oncotic pressure of diaspirin cross-linked hemoglobin (DCLHb) on brain injury after temporary focal cerebral ischemia in rats", ANESTHESIA & ANALGESIA, loma linda univ. ca, (1996), vol. 83, no. 2, pages 342 - 347, XP002208454 [X] 1-25 cf. abstract, page 346, left-sided col., last para. bridging with right-sided col., 1st para. DOI: http://dx.doi.org/10.1097/00000539-199608000-00024
		[X] - J.E. CHAPPELL ET AL., "Hemodilution with diaspirin-cross-linked hemoglobin lowers intracranial pressure, improves cerebral perfusion pressure, and reduces fluid requirement following head injury and shock", SURGICAL FORUM, (1995), vol. 46, no. 0, pages 569 - 571, XP002208455 [X] 1-25 cf. abstract, page 571, last para., "discussion"
		[A] - S.M. COHN ET AL., "Diaspirin cross-linked hemoglobin resucitation of hemorrhage: comparison ofa blood substitute with hypertonic saline and isotonic saline", JOURNAL OF TRAUMA, (1995), vol. 39, no. 2, pages 210 - 217, XP002208456 [A] 1-25 cf. abstract DOI: http://dx.doi.org/10.1097/00005373-199508000-00005
	International search	[X] - SURGICAL FORUM, 1995, Vol. 46, No. 1, CHAPPELL J.E. et al., "Hemodilution with Diaspirin Cross-Linked Hemoglobin Lowers Intracranial Pressure, Improves Cerebral Perfusion Pressure and Reduces Fluid Requirement Following Head Injury and Shock", pages 569-571.
		[X] - CAN. J. NEUR. SCI., 1993, Vol. 20, COLE D.J. et al., "Focal Cerebral Ischemia in Rats Effect of Hemodilution with Alpha-Alpha Cross-Linked Hemoglobin on Brain Injury and Edema", page 30-36.
		[X] - ANESTH., February 1993, Vol. 8, No. 2, COLE D.J. et al., "Focal Cerebral Ischemia in Rats Effect of Hypervolemic Hemodilution with Diaspirin Cross-Linked Hemoglobin Versus Albumin on Brain Injury and Edema", pages 335-342.
		[Y] - J. LAB. CLIN. MED., February 1991, Vol. 117, No. 2, PRZYBELSKI R.J. et al., "Cross-Linked Hemoglobin Solution as a Resuscitative Fluid After Hemorrhage in the Rat", pages 143-151.
		[Y] - ANESTH. ANALG., 1992, Vol. 74, SCHELL R.M. et al., "Hemodilution During Cerebral Ischemia in Rats: Effects of Stroma-Free Hemoglobin on Blood Flow", S262.

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