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Extract from the Register of European Patents

EP About this file: EP0995437

EP0995437 - 2,3-DIHYDROBENZOFURAN DERIVATIVES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  17.09.2004
Database last updated on 08.10.2024
Most recent event   Tooltip25.07.2008Change - representativepublished on 27.08.2008  [2008/35]
Applicant(s)For all designated states
CHUGAI SEIYAKU KABUSHIKI KAISHA
5-1, Ukima 5-chome, Kita-ku
Tokyo, 115-8543 / JP
[N/P]
Former [2000/17]For all designated states
CHUGAI SEIYAKU KABUSHIKI KAISHA
5-1, Ukima 5-chome, Kita-ku
Tokyo, 115-8543 / JP
Inventor(s)01 / ISHIKAWA, Akira, Chugai Seiyaku Kabushiki Kaisha
135, Komakado 1-chome
Gotenba-shi, Shizuoka 412-8513 / JP
02 / KATO, Yoshiaki, Chugai Seiyaku Kabushiki Kaisha
135, Komakado 1-chome
Gotenba-shi, Shizuoka 412-8513 / JP
03 / TAMURA, Kunio, Chugai Seiyaku Kabushiki Kaisha
135, Komakado 1-chome
Gotenba-shi, Shizuoka 412-8513 / JP
04 / TAKASHIMA, Yoshiaki, Chugai Seiyaku K.K.
135, Komakado 1-chome
Gotenba-shi, Shizuoka 412-8513 / JP
05 / CYNSHI, Osamu, Chugai Seiyaku Kabushiki Kaisha
135, Komakado 1-chome
Gotenba-shi, Shizuoka 412-8513 / JP
[2000/17]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2008/35]Vossius & Partner
Siebertstrasse 3
81675 München / DE
Former [2000/17]VOSSIUS & PARTNER
Siebertstrasse 4
81675 München / DE
Application number, filing date98921762.522.05.1998
[2000/17]
WO1998JP02248
Priority number, dateJP1997017088923.05.1997         Original published format: JP 17088997
[2000/17]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9852557
Date:26.11.1998
Language:EN
[1998/47]
Type: A1 Application with search report 
No.:EP0995437
Date:26.04.2000
Language:EN
The application published by WIPO in one of the EPO official languages on 26.11.1998 takes the place of the publication of the European patent application.
[2000/17]
Search report(s)International search report - published on:JP26.11.1998
(Supplementary) European search report - dispatched on:EP19.12.2001
ClassificationIPC:A61K31/34, C07D307/79, C07D307/94
[2000/17]
CPC:
C07D307/79 (EP,US); A61K31/34 (KR); A61K31/343 (EP,US);
C07D307/94 (EP,US)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2000/17]
TitleGerman:2,3-DIHYDROBENZOFURAN DERIVATE[2000/17]
English:2,3-DIHYDROBENZOFURAN DERIVATIVES[2000/17]
French:DERIVES DE 2,3-DIHYDROBENZOFURANE[2000/17]
Entry into regional phase21.12.1999Translation filed 
21.12.1999National basic fee paid 
21.12.1999Search fee paid 
21.12.1999Designation fee(s) paid 
21.12.1999Examination fee paid 
Examination procedure15.06.1998Request for preliminary examination filed
International Preliminary Examining Authority: JP
21.12.1999Examination requested  [2000/17]
21.11.2002Despatch of a communication from the examining division (Time limit: M06)
16.05.2003Reply to a communication from the examining division
12.08.2003Despatch of a communication from the examining division (Time limit: M04)
10.10.2003Reply to a communication from the examining division
11.12.2003Communication of intention to grant the patent
22.04.2004Application deemed to be withdrawn, date of legal effect  [2004/45]
01.06.2004Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2004/45]
Fees paidRenewal fee
30.05.2000Renewal fee patent year 03
31.05.2001Renewal fee patent year 04
31.05.2002Renewal fee patent year 05
30.05.2003Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
31.05.200407   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[E]EP0950405  (CHUGAI PHARMACEUTICAL CO LTD [JP]) [E] 7,15,18 * tables 1-3,5-15 *;
 [E]EP0868913  (CHUGAI PHARMACEUTICAL CO LTD [JP]) [E] 7,15,18 * examples; page 6 - page 8; tables 1-5 *;
 [PX]WO9741844  (ALCON LAB INC [US], et al) [PX] 7,15,18 * page 6, line 20 - page 7, line 13 * * claims 16,18 *;
 [E]WO9834646  (UNIV HERTFORDSHIRE [GB], et al) [E] 7,15,18 * page 9, lines 7,8,15; claim 3 *;
 [X]JPH08109179  (ONO PHARMACEUTICAL CO) [X] 7,15 * column 163; example 0462 * * column 164; example 0472 *;
 [X]  - HAMMOND M L ET AL, "2,3-DIHYDRO-5-BENZOFURANOLS AS ANTIOXIDANT-BASED INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (19890501), vol. 32, no. 5, ISSN 0022-2623, pages 1006 - 1020, XP002009522 [X] 7,15,18 * examples 62-64,68-70; tables 1,2 *

DOI:   http://dx.doi.org/10.1021/jm00125a014
 [X]  - HAMMOND M L ET AL, "ANTIOXIDANT-BASED INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS. THE DISCOVERY OF 6-(1-(2-(HYDROXYMETHYL)PHENYL)-1-PROPEN-3-YL)-2,3- DIHYDRO-5-BENZOFURANOL, A POTENT TOPICAL ANTIINFLAMMATORY AGENT", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (19900301), vol. 33, no. 3, ISSN 0022-2623, pages 908 - 918, XP000673907 [X] 7,15,18 * table 3 *

DOI:   http://dx.doi.org/10.1021/jm00165a005
 [X]  - "New alkyl-hydroxy-benzofuran and derivatives - are 5-lipoxygenase inhibitors useful in allergy or inflammation e.g. bronchial asthma, rheumatic disease, psoriasis", WPI WORLD PATENT INFORMATION DERWENT, DERWENT, GB, vol. 51, no. 95, XP002009524 [X] 1,15,18 * the whole document *
International search[YP]JPH1072458  (CHUGAI PHARMACEUTICAL CO LTD);
 [X]GB2221680  (MERCK & CO INC [US]);
 [X]  - HAMMOND M. L., ET AL., "2,3-DIHYDRO-5-BENZOFURANOLS AS ANTIOXIDANT-BASED INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS.", Journal of Medicinal Chemistry, American Chemical Society, US, US, (19890101), vol. 32., no. 05., doi:10.1021/jm00125a014, ISSN 0022-2623, pages 1006 - 1020., XP002913147

DOI:   http://dx.doi.org/10.1021/jm00125a014
 [X]  - AYA KURANAKA et al., "Antioxidation Mechanism of Vitamin E (in Japanese)", VITAMIN, 1991, Vol. 65, No. 9, pages 453-458.
 [Y]  - MUKAI K., OKABE K., HOSOSE H., "SYNTHESIS AND STOPPED-FLOW INVESTIGATION OF ANTIOXIDANT ACTIVITY OF TOCOPHEROLS. FINDING OF NEW TOCOPHEROL DERIVATIVES HAVING THE HIGHEST ANTIOXIDANT ACTIVITY AMONG PHENOLIC ANTIOXIDANTS.", The Journal of Organic Chemistry, American Chemical Society, US, US, (19890101), vol. 54., no. 03., doi:10.1021/jo00264a011, ISSN 0022-3263, pages 557 - 560., XP002913148

DOI:   http://dx.doi.org/10.1021/jo00264a011
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.