Deutsch English Français

Contact

EP1003543

European procedure

Quick help

Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...

News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...

Extract from the Register of European Patents

EP About this file: EP1003543

EP1003543 - APOPTOSIS-INDUCING GELSOLIN SEQUENCES [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 12.04.2002 Database last updated on 14.08.2024
Most recent event Tooltip	08.08.2008	Change - applicant	published on 10.09.2008 [2008/37]
Applicant(s)	For all designated states CHIRON CORPORATION 4560 Horton Street Emeryville CA 94608-2916 / US
	[2008/37]
Former [2000/22]	For all designated states CHIRON CORPORATION 4560 Horton Street Emeryville California 94608-2916 / US
Inventor(s)	01 / KOTHS, Kirston 4650 Horton Street Emeryville, CA 94608-2916 / US
	02 / KOTHAKOTA, Srinivas 4560 Horton Street Emeryville, CA 94608-2916 / US
	03 / WILLIAMS, Louis, T. 4650 Horton Street Emeryville, CA 94608-2916 / US
	04 / REINHART, Christoph 4650 Horton Street Emeryville, CA 94608-2916 / US
	[2000/22]
Representative(s)	Goldin, Douglas Michael, et al J.A. KEMP & CO. 14 South Square Gray's Inn London WC1R 5JJ / GB
	[N/P]
Former [2000/22]	Goldin, Douglas Michael, et al J.A. KEMP & CO. 14 South Square Gray's Inn London WC1R 5LX / GB
Application number, filing date	98923505.6	18.05.1998
	[2000/22]
	WO1998US10181
Priority number, date	US19970047080P	19.05.1997 Original published format: US 47080 P
	[2000/22]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9852597
	Date:	26.11.1998
	Language:	EN
	[1998/47]
	Type:	A1 Application with search report
	No.:	EP1003543
	Date:	31.05.2000
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 26.11.1998 takes the place of the publication of the European patent application.
	[2000/22]
Search report(s)	International search report - published on:	US	26.11.1998
	(Supplementary) European search report - dispatched on:	EP	08.08.2001
Classification	IPC:	C12N15/12, C07K14/47, C12N15/63, C12N5/10, A61K38/17, A61K48/00, C12Q1/68, G01N33/53	[2001/38]
	CPC:	C07K14/4702 (EP); A61P35/00 (EP); A61P43/00 (EP); A61K38/00 (EP); A61K48/00 (EP)
	Former IPC [2000/22]	A61K38/17, A61K48/00, C12N1/00, C12N5/10, C12N15/12, C12N15/63, C12Q1/37, C12Q1/68
Designated contracting states	AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2000/22]
Title	German:	APOPTOSE-INDUZIERENDE GELSOLINSEQUENZEN	[2000/22]
	English:	APOPTOSIS-INDUCING GELSOLIN SEQUENCES	[2000/22]
	French:	SEQUENCES DE GELSOLINE INDUISANT L'APOPTOSE	[2000/22]
Entry into regional phase	29.11.1999	National basic fee paid
	29.11.1999	Search fee paid
	29.11.1999	Designation fee(s) paid
	29.11.1999	Examination fee paid
Examination procedure	26.10.1998	Request for preliminary examination filed International Preliminary Examining Authority: US
	29.11.1999	Examination requested [2000/22]
	21.10.2001	Application deemed to be withdrawn, date of legal effect [2002/22]
	29.11.2001	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2002/22]
Fees paid	Renewal fee
	29.11.1999	Renewal fee patent year 03
	Penalty fee
	Additional fee for renewal fee
	31.05.2001	04 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[X]US5508265 (STOSSEL THOMAS P [US], et al) [X] 1,12 * gelsolin/fragments and their use in therapeutic composition (e.g. decreasing levels of actin in the bloodstream); column 7 - column 8 *;
		[X] - WEN D ET AL, "THE PLASMA AND CYTOPLASMIC FORMS OF HUMAN GELSOLIN DIFFER IN DISULFIDE STRUCTURE", BIOCHEMISTRY,US,AMERICAN CHEMICAL SOCIETY. EASTON, PA, (19960730), vol. 35, no. 30, ISSN 0006-2960, pages 9700 - 9709, XP002045563 [X] 1-10 * page 9701, column R, paragraph SECOND * DOI: http://dx.doi.org/10.1021/bi960920n
		[X] - DIEFFENBACH C W ET AL, "CLONING OF MURINE CELSOLIN AND ITS REGULATION DURING DIFFERENTIATION OF EMBRYONAL CARCINOMA CELLS", JOURNAL OF BIOLOGICAL CHEMISTRY,US,AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, (19890805), vol. 264, no. 22, ISSN 0021-9258, pages 13281,13283 - 13288, XP002911330 [X] 1-10 * page 13282, column R; figure 2 *
		[A] - PAUNIO TIINA ET AL, "Toward understanding the pathogenic mechanisms in gelsolin-related amyloidosis: In vitro expression reveals an abnormal gelsolin fragment.", HUMAN MOLECULAR GENETICS, (1994), vol. 3, no. 12, ISSN 0964-6906, pages 2223 - 2229, XP000999605 [A] 1-14 * the whole document * DOI: http://dx.doi.org/10.1093/hmg/3.12.2223
		[T] - KAMADA SHINJI ET AL, "A cloning method for caspase substrates that uses the yeast two-hybrid system: Cloning of the antiapoptotic gene gelsolin", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA,NATIONAL ACADEMY OF SCIENCE. WASHINGTON,US, (19980721), vol. 95, no. 15, ISSN 0027-8424, pages 8532 - 8537, XP002158013 [T] 1-18 * the whole document * DOI: http://dx.doi.org/10.1073/pnas.95.15.8532
		[PX] - OHTSU MAKOTO ET AL, "Inhibition of apoptosis by the actin-regulatory protein gelsolin.", EMBO (EUROPEAN MOLECULAR BIOLOGY ORGANIZATION) JOURNAL, (1997), vol. 16, no. 15, ISSN 0261-4189, pages 4650 - 4656, XP000999489 [PX] 1-18 * the whole document * DOI: http://dx.doi.org/10.1093/emboj/16.15.4650
	International search	[A] - POLTSCH M. C., ET AL., "CHARACTERIZATION OF THE ENDOGENOUS DEOXYRIBONUCLEASE INVOLVED IN NUCLEAR DNA DEGRADATION DURING APOPTOSIS (PROGRAMMED CELL DEATH).", EMBO JOURNAL., OXFORD UNIVERSITY PRESS, SURREY., GB, GB, (19930101), vol. 12., no. 01., ISSN 0261-4189, pages 371 - 377., XP002910319
		[XP] - KOTHAKOTA S., ET AL., "CASPASE-3-GENERATED FRAGMENT OF GELSOLIN: EFFECTOR OF MORPHOLOGICAL CHANGE IN APOPTOSIS.", Science, American Association for the Advancement of Science, US, US, (19971010), vol. 278., no. 5336., doi:10.1126/science.278.5336.294, ISSN 0036-8075, pages 294 - 298., XP002910320 DOI: http://dx.doi.org/10.1126/science.278.5336.294
		[XP] - DOSAKA-AKITA H., ET AL., "FREQUENT LOSS OF GELSOLIN EXPRESSION IN NON-SMALL CELL LUNG CANCERS OF HEAVY SMOKERS.", Cancer Research, American Association for Cancer Research, US, US, (19980115), vol. 58., no. 02., ISSN 0008-5472, pages 322 - 327., XP002910321
		[X] - TANAKA M., ET AL., "GELSOLIN: A CANDIDATE FOR SUPPRESSOR OF HUMAN BLADDER CANCER.", Cancer Research, American Association for Cancer Research, US, US, (19950801), vol. 55., no. 15., ISSN 0008-5472, pages 3228 - 3232., XP002910322
		[X] - KWIATKOWSKI D. J., JANMEY P. A., YIN H. L., "IDENTIFICATION OF CRITICAL FUNCTIONAL AND REGULATORY DOMAINS IN GELSOLIN.", The journal of cell biology : JCB, The Rockefeller University Press, US, US, (19890501), vol. 108., no. 05., doi:10.1083/jcb.108.5.1717, ISSN 0021-9525, pages 1717 - 1726., XP002910323 DOI: http://dx.doi.org/10.1083/jcb.108.5.1717
		[X] - TANAKA M., ET AL., "IN VIVO THERAPY WITH GELSOLIN GENE FOR HUMAN BLADDER CANCERS.", Cancer Gene Therapy, Appleton & Lange, GB, GB, (19961101), vol. 03., no. 06., ISSN 0929-1903, page 116., XP002910324

The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.

Legal notice
Terms of use
24.2.25; 35p