| EP1100885 - RAPID SUBCLONING USING SITE-SPECIFIC RECOMBINATION [Right-click to bookmark this link] | Status | The application has been refused Status updated on 27.04.2007 Database last updated on 11.04.2026 | Most recent event Tooltip | 18.07.2008 | Change - representative | published on 20.08.2008 [2008/34] | Applicant(s) | For all designated states BAYLOR COLLEGE OF MEDICINE One Baylor Plaza Houston, TX 77030 / US | [2001/21] | Inventor(s) | 01 /
ELLEDGE, Stephen, J., Dr. BCMT-T303, Baylor College of Medicine Houston, TX 77030 / US | 02 /
LIU, Qinghua Apt. 26-2G, 2900 Cambridge Houston, TX 77054 / US | [2001/31] |
| Former [2001/21] | 01 /
ELLEDGE, Stephen, J. 2505 Wordsworth Avenue Houston, TX 77030 / US | ||
| 02 /
LIU, Qinghua Apt. 26-2G, 2900 Cambridge Houston, TX 77054 / US | Representative(s) | Uexküll & Stolberg Partnerschaft von Patent- und Rechtsanwälten mbB Beselerstrasse 4 22607 Hamburg / DE | [N/P] |
| Former [2008/34] | UEXKÜLL & STOLBERG Patentanwälte Beselerstrasse 4 22607 Hamburg / DE | ||
| Former [2001/21] | UEXKÜLL & STOLBERG Patentanwälte Beselerstrasse 4 22607 Hamburg / DE | Application number, filing date | 98937141.4 | 27.07.1998 | [2001/21] | WO1998US15481 | Priority number, date | US19980122384 | 24.07.1998 Original published format: US 122384 | [2001/21] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO0005355 | Date: | 03.02.2000 | Language: | EN | [2000/05] | Type: | A1 Application with search report | No.: | EP1100885 | Date: | 23.05.2001 | Language: | EN | The application published by WIPO in one of the EPO official languages on 03.02.2000 takes the place of the publication of the European patent application. | [2001/21] | Search report(s) | International search report - published on: | US | 03.02.2000 | (Supplementary) European search report - dispatched on: | EP | 31.10.2001 | Classification | IPC: | C12N15/00, C12N15/09, C12N15/63, C12P21/06 | [2001/21] | CPC: |
C12N15/905 (EP);
C12N15/66 (EP)
| Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2001/21] | Title | German: | SCHNELLE SUBKLONIERUNG MITTELS ORTSSPEZIFISCHER REKOMBINATION | [2001/21] | English: | RAPID SUBCLONING USING SITE-SPECIFIC RECOMBINATION | [2001/21] | French: | SOUS-CLONAGE RAPIDE FAISANT APPEL A UNE RECOMBINAISON SPECIFIQUE A UN SITE | [2001/21] | Entry into regional phase | 14.02.2001 | National basic fee paid | 14.02.2001 | Search fee paid | 14.02.2001 | Designation fee(s) paid | 14.02.2001 | Examination fee paid | Examination procedure | 09.02.2000 | Request for preliminary examination filed International Preliminary Examining Authority: US | 14.02.2001 | Examination requested [2001/21] | 20.04.2001 | Amendment by applicant (claims and/or description) | 30.07.2004 | Despatch of a communication from the examining division (Time limit: M06) | 08.02.2005 | Reply to a communication from the examining division | 03.05.2006 | Cancellation of oral proceeding that was planned for 10.05.2006 | 03.05.2006 | Minutes of oral proceedings despatched | 10.05.2006 | Date of oral proceedings (cancelled) | 18.05.2006 | Despatch of communication that the application is refused, reason: substantive examination [2007/22] | 13.04.2007 | Application refused, date of legal effect [2007/22] | Appeal following examination | 18.07.2006 | Appeal received No. T1780/06 | 20.04.2007 | Result of appeal procedure: appeal of the applicant inadmissible | Request for further processing for: | 08.02.2005 | Request for further processing filed | 08.02.2005 | Full payment received (date of receipt of payment) Request granted | 24.02.2005 | Decision despatched | Fees paid | Renewal fee | 14.02.2001 | Renewal fee patent year 03 | 12.07.2001 | Renewal fee patent year 04 | 12.07.2002 | Renewal fee patent year 05 | 14.07.2003 | Renewal fee patent year 06 | 14.07.2004 | Renewal fee patent year 07 | 13.07.2005 | Renewal fee patent year 08 | 12.07.2006 | Renewal fee patent year 09 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X] SAUER B ET AL: "CONSTRUCTION OF ISOGENIC CELL LINES EXPRESSING HUMAN AND RAT ANGIOTENSIN II AT1 RECEPTORS BY CRE-MEDIATED SITE-SPECIFIC RECOMBINATION", METHODS: A COMPANION TO METHODS IN ENZYMOLOGY, ACADEMIC PRESS INC., NEW YORK, NY, US, vol. 4, no. 2, 1992, pages 143 - 149, XP000613888, ISSN: 1046-2023 DOI: http://dx.doi.org/10.1016/1046-2023(92)90046-B | [X] AKAGI K ET AL: "CRE-MEDIATED SOMATIC SITE-SPECIFIC RECOMBINATION IN MICE", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 25, no. 9, 1997, pages 1766 - 1773, XP001004602, ISSN: 0305-1048 DOI: http://dx.doi.org/10.1093/nar/25.9.1766 | [X] QIN M ET AL: "CRE RECOMBINASE-MEDIATED SITE-SPECIFIC RECOMBINATION BETWEEN PLANT CHROMOSOMES", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 91, no. 5, 1 March 1994 (1994-03-01), pages 1706 - 1710, XP000615549, ISSN: 0027-8424 DOI: http://dx.doi.org/10.1073/pnas.91.5.1706 | [X] ODELL J T ET AL: "SEED-SPECIFIC GENE ACTIVATION MEDIATED BY THE CRE/LOX SITE-SPECIFIC RECOMBINATION SYSTEM", PLANT PHYSIOLOGY, AMERICAN SOCIETY OF PLANT PHYSIOLOGISTS, ROCKVILLE, MD, US, vol. 106, no. 2, 1 October 1994 (1994-10-01), pages 447 - 458, XP002912196, ISSN: 0032-0889 DOI: http://dx.doi.org/10.1104/pp.106.2.447 | [T] LIU QINGHUA ET AL: "The univector plasmid-fusion system, a method for rapid construction of recombinant DNA without restriction enzymes.", CURRENT BIOLOGY, vol. 8, no. 24, 3 December 1998 (1998-12-03), pages 1300 - 1309, XP002155212, ISSN: 0960-9822 DOI: http://dx.doi.org/10.1016/S0960-9822(07)00560-X | [Y] HALL RUTH M ET AL: "Mobile gene cassettes and integrons: Capture and spread of genes by site-specific recombination.", MOLECULAR MICROBIOLOGY, vol. 15, no. 4, 1995, pages 593 - 600, XP001028961, ISSN: 0950-382X [Y] 1-31 * the whole document * DOI: http://dx.doi.org/10.1111/j.1365-2958.1995.tb02368.x | [Y] ELLEDGE S J ET AL: "LAMBDAYES A MULTIFUNCTIONAL COMPLEMENTARY DNA EXPRESSION VECTOR FOR THE ISOLATION OF GENES BY COMPLEMENTATION OF YEAST AND ESCHERICHIA-COLI MUTATIONS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 88, no. 5, 1991, 1991, pages 1731 - 1735, XP002916290, ISSN: 0027-8424 DOI: http://dx.doi.org/10.1073/pnas.88.5.1731 | [Y] KILBY N J ET AL: "SITE-SPECIFIC RECOMBINASES: TOOLS FOR GENOME ENGINEERING", TRENDS IN GENETICS, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 9, no. 12, 1993, pages 413 - 421, XP002916291, ISSN: 0168-9525 DOI: http://dx.doi.org/10.1016/0168-9525(93)90104-P | [A] BOUHASSIRA ERIC E ET AL: "Transcriptional behavior of LCR enhancer elements integrated at the same chromosomal locus by recombinase-mediated cassette exchange.", BLOOD, vol. 90, no. 9, 1997, pages 3332 - 3344, XP002143981, ISSN: 0006-4971 | [A] SCHLAKE THOMAS ET AL: "Use of Mutated FLP Recognition Target (FRT) Sites for the Exchange of Expression Cassettes at Defined Chromosomal Loci.", BIOCHEMISTRY, vol. 33, no. 43, 1994, pages 12746 - 12751, XP000616165, ISSN: 0006-2960 [A] 1-31 * the whole document * DOI: http://dx.doi.org/10.1021/bi00209a003 | [Y] ALADJEM MIRIT I ET AL: "Positive of FLP-mediated unequal sister chromatid exchange products in mammalian cells.", MOLECULAR AND CELLULAR BIOLOGY, vol. 17, no. 2, 1997, pages 857 - 861, XP002180200, ISSN: 0270-7306 | [X] ANGRAND PIERRE-OLIVIER ET AL: "Inducible expression based on regulated recombination: A single vector strategy for stable expression in cultured cells.", NUCLEIC ACIDS RESEARCH, vol. 26, no. 13, 1 July 1998 (1998-07-01), pages 3263 - 3269, XP001021788, ISSN: 0305-1048 [X] 1-31 * The whole document, see specially Figure 1. * DOI: http://dx.doi.org/10.1093/nar/26.13.3263 | Examination | AUBRECHT ET AL, GENE, vol. 172, 1996, pages 227 - 231, XP000404274 |