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Extract from the Register of European Patents

EP About this file: EP1025121

EP1025121 - PEPTIDES CAPABLE OF INHIBITING THE INTERACTION BETWEEN PRESENILINS AND THE BETA-AMYLOID PEPTIDE OR ITS PRECURSOR [Right-click to bookmark this link]
Former [2000/32]PEPTIDES CAPABLE OF INHIBITING THE INTERACTION BETWEEN PRESENILINS AND THE $g(b)-AMYLOID PEPTIDE OR ITS PRECURSOR
[2010/49]
StatusNo opposition filed within time limit
Status updated on  29.06.2012
Database last updated on 15.07.2024
Most recent event   Tooltip29.06.2012No opposition filed within time limitpublished on 01.08.2012  [2012/31]
Applicant(s)For all designated states
Aventis Pharma S.A.
20, avenue Raymond Aron
92160 Antony / FR
[2000/32]
Inventor(s)01 / CZECH, Christian
4, Cité de l'Alma
F-75007 Paris / FR
02 / MERCKEN, Luc
18 bis, rue Jules Joffrin
F-94100 Saint Maur / FR
03 / PRADIER, Laurent
23, avenue Cambacérès
F-91370 Verrières / FR
04 / REBOUL-BECQUART, Soline
10, avenue de Verdun
F-92120 Montrouge / FR
[2000/32]
Representative(s)Bouvet, Philippe
Aventis Pharma S.A.
Direction des Brevets Tri LEO/144
20 Avenue Raymond Aron
92165 Antony Cedex / FR
[N/P]
Former [2000/32]Bouvet, Philippe
Rhône-Poulenc Rorer S.A. 20, Avenue Raymond Aron
92160 Antony / FR
Application number, filing date98951547.323.10.1998
[2000/32]
WO1998FR02278
Priority number, dateFR1997001338424.10.1997         Original published format: FR 9713384
US19980095671P07.08.1998         Original published format: US 95671 P
[2000/32]
Filing languageFR
Procedural languageFR
PublicationType: A1 Application with search report
No.:WO9921886
Date:06.05.1999
Language:FR
[1999/18]
Type: A1 Application with search report 
No.:EP1025121
Date:09.08.2000
Language:FR
The application published by WIPO in one of the EPO official languages on 06.05.1999 takes the place of the publication of the European patent application.
[2000/32]
Type: B1 Patent specification 
No.:EP1025121
Date:24.08.2011
Language:FR
[2011/34]
Search report(s)International search report - published on:EP06.05.1999
ClassificationIPC:C07K14/47, C12N15/12, C12N5/10, C12N15/86, C07K16/18
[2000/32]
CPC:
G01N33/502 (EP); C07K14/47 (KR); A61P25/28 (EP);
C07K14/4711 (EP); G01N33/5008 (EP); G01N33/542 (EP);
G01N33/6896 (EP); A61K38/00 (EP); A61K48/00 (EP);
C07K2319/02 (EP); C12N2799/021 (EP); G01N2333/4709 (EP);
G01N2500/02 (EP) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   NL,   PT,   SE [2000/32]
Extension statesSI25.04.2000
TitleGerman:PEPTIDE DIE DIE WECHSELWIRKUNG ZWISCHEN PRESENILINEN UND BETA-AMYLOIDPEPTID ODER SEINEM VORLÄUFER HEMMEN[2011/08]
English:PEPTIDES CAPABLE OF INHIBITING THE INTERACTION BETWEEN PRESENILINS AND THE BETA-AMYLOID PEPTIDE OR ITS PRECURSOR[2010/49]
French:PEPTIDES CAPABLES D'INHIBER L'INTERACTION ENTRE LES PRESENILINES ET LE PEPTIDE BETA-AMYLOIDE OU SON PRECURSEUR[2010/49]
Former [2000/32]PEPTIDE DIE DIE WECHSELWIRKUNG ZWISCHEN PRESENILINS UND BETA-AMYLOIDPEPTID ODER SEIN VORLÄUFER HEMMEN
Former [2000/32]PEPTIDES CAPABLE OF INHIBITING THE INTERACTION BETWEEN PRESENILINS AND THE $g(b)-AMYLOID PEPTIDE OR ITS PRECURSOR
Former [2000/32]PEPTIDES CAPABLES D'INHIBER L'INTERACTION ENTRE LES PRESENILINES ET LE PEPTIDE SS-AMYLOIDE OU SON PRECURSEUR
Entry into regional phase25.04.2000National basic fee paid 
25.04.2000Designation fee(s) paid 
25.04.2000Examination fee paid 
Examination procedure12.05.1999Request for preliminary examination filed
International Preliminary Examining Authority: EP
25.04.2000Examination requested  [2000/32]
04.04.2007Despatch of a communication from the examining division (Time limit: M06)
15.10.2007Reply to a communication from the examining division
02.06.2008Despatch of a communication from the examining division (Time limit: M04)
23.07.2008Reply to a communication from the examining division
22.07.2009Despatch of a communication from the examining division (Time limit: M02)
14.09.2009Reply to a communication from the examining division
29.10.2010Cancellation of oral proceeding that was planned for 26.11.2010
26.11.2010Date of oral proceedings (cancelled)
08.02.2011Communication of intention to grant the patent
31.05.2011Fee for grant paid
31.05.2011Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  04.04.2007
Opposition(s)25.05.2012No opposition filed within time limit [2012/31]
Fees paidRenewal fee
22.09.2000Renewal fee patent year 03
15.10.2001Renewal fee patent year 04
31.10.2002Renewal fee patent year 05
31.10.2003Renewal fee patent year 06
02.11.2004Renewal fee patent year 07
31.10.2005Renewal fee patent year 08
12.10.2006Renewal fee patent year 09
12.10.2007Renewal fee patent year 10
31.03.2008Renewal fee patent year 11
13.10.2009Renewal fee patent year 12
11.10.2010Renewal fee patent year 13
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Cited inInternational search[A]WO9213069  (IMPERIAL COLLEGE [GB]) [A] 1,8-10,16,20 * page 47 - page 48 *;
 [A]WO9634099  (HSC RES DEV LP [CA], et al) [A] 1-7,11,12,16-19,21-51 * page 3, line 21 - page 10, line 17 * * page 11, line 2 - page 12, line 6 *;
 [YA]WO9727296  (HSC RES DEV LP [CA], et al) [Y] 1 * page 56, line 10 - page 59, line 2 * [A] 11,12,20-22,36-38,42-51;
    [DYAX] - XIA W ET AL, "Interaction between amyloid precursor protein and presenilins in mammalian cells: Implications for the pathogenesis of Alzheimer disease", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA., WASHINGTON US, (199707), vol. 94, pages 8208 - 8213, XP002067171 [DY] 1 * the whole document * [A] 2-10,16-22,24,25,33,38,40 [X] 23,44

DOI:   http://dx.doi.org/10.1073/pnas.94.15.8208
 [A]  - KIM S S ET AL, "Lack of interactions between amyloid precursor protein and hydrophilic domains of presenilin 1 and 2 using the yeast two hybrid system", JOURNAL OF MOLECULAR NEUROSCIENCE, TOTOWA US, (199708), vol. 9, no. 1, pages 49 - 54, XP002072945 [A] 1 * the whole document *
 [DXA]  - WEIDEMANN A ET AL., "Formation of stable complexes between two Alzheimer's disease gene products: Presenilin-2 and beta amyloid precursor protein", NATURE MEDICINE., NEW YORK US, (199703), vol. 3, no. 3, pages 328 - 332, XP002067172 [DX] 21,44 * the whole document * [A] 1,24,25,33

DOI:   http://dx.doi.org/10.1038/nm0397-328
 [A]  - WARAGAI M ET AL., "Presenilin 1 binds to amyloid precursor protein directly", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., ORLANDO, FL US, (19971020), vol. 239, pages 480 - 482, XP002094076 [A] 1 * the whole document *

DOI:   http://dx.doi.org/10.1006/bbrc.1997.7488
 [PX]  - WEIDEMANN A ET AL., "Modulation of APP metabolism by presenilin-2 derivatives", SOCIETY FOR NEOROSCIENCE ABSTRACTS, US, (19971025), vol. 23, no. 1-2, page 1118, XP002094077 [PX] 1-3,24,25,33 * voir abérégé no. 443.10 *
 [T]  - HAAS C ET AL., "A technical KO of amyloid-beta peptide", NATURE., LONDON GB, (19980122), vol. 391, pages 339 - 340, XP002094078 [T] 1 * the whole document *

DOI:   http://dx.doi.org/10.1038/34800
 [T]  - THINAKARAN G ET AL, "Stable association of presenilin derivatives and absence of presenilin interactions with APP", NEUROBIOLOGY OF DISEASE, NEW YORK US, (1998), vol. 4, no. 6, pages 438 - 453, XP002072947 [T] 1 * the whole document *

DOI:   http://dx.doi.org/10.1006/nbdi.1998.0171
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.