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Extract from the Register of European Patents

EP About this file: EP0955301

EP0955301 - 7-aza-bicyclo 2.2.1 -heptane derivatives, their preparation and use according to their affinity for neuronal nicotinic acetylcholine receptors [Right-click to bookmark this link]
Former [1999/45]7-aza-bicyclo[2.2.1]-heptane derivatives, their preparation and use according to their affinity for neuronal nicotinic acetylchloline receptors
[1999/47]
StatusThe application is deemed to be withdrawn
Status updated on  15.02.2008
Database last updated on 19.10.2024
Most recent event   Tooltip15.02.2008Application deemed to be withdrawnpublished on 19.03.2008  [2008/12]
Applicant(s)For all designated states
Pfizer Products Inc.
Eastern Point Road
Groton, CT 06340 / US
[N/P]
Former [1999/45]For all designated states
Pfizer Products Inc.
Eastern Point Road
Groton, Connecticut 06340 / US
Inventor(s)01 / Yohannes, Daniel
600 Meridian Street Ext. No. 403
Groton, Connecticut 06340 / US
02 / Bundesmann, Mark Werner
61 East Main Street
Mystic, Connecticut 06355 / US
[1999/45]
Representative(s)O'Brien, Niall James, et al
Urquhart-Dykes & Lord LLP
30 Welbeck Street
London W1G 8ER / GB
[N/P]
Former [2006/09]O'Brien, Niall James, et al
Urquhart-Dykes & Lord LLP 30 Welbeck Street
GB-London W1G 8ER / GB
Former [1999/45]Simpson, Alison Elizabeth Fraser, et al
Urquhart-Dykes & Lord, 91 Wimpole Street
London W1M 8AH / GB
Application number, filing date99302306.825.03.1999
[1999/45]
Priority number, dateUS19980083108P27.04.1998         Original published format: US 83108 P
[1999/45]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP0955301
Date:10.11.1999
Language:EN
[1999/45]
Type: A3 Search report 
No.:EP0955301
Date:18.04.2001
[2001/16]
Search report(s)(Supplementary) European search report - dispatched on:EP28.02.2001
ClassificationIPC:C07D487/08, A61K31/40, A61K31/44, A61K31/41, A61K31/505, // (C07D487/08, 209:00, 209:00)
[2000/48]
CPC:
C07D487/08 (EP,US); A61P1/00 (EP); A61P1/04 (EP);
A61P21/00 (EP); A61P25/00 (EP); A61P25/04 (EP);
A61P25/06 (EP); A61P25/08 (EP); A61P25/14 (EP);
A61P25/16 (EP); A61P25/18 (EP); A61P25/20 (EP);
A61P25/22 (EP); A61P25/24 (EP); A61P25/28 (EP);
A61P25/30 (EP); A61P25/34 (EP); A61P29/00 (EP);
A61P29/02 (EP); A61P3/00 (EP); A61P3/04 (EP);
A61P35/00 (EP); A61P9/00 (EP); A61P9/06 (EP);
A61P9/12 (EP); Y02P20/55 (EP,US) (-)
Former IPC [1999/45]C07D487/08, A61K31/44, // (C07D487/08, 209:00, 209:00)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   NL,   PT,   SE [2002/02]
Former [1999/45]AT,  BE,  CH,  CY,  DE,  DK,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE 
TitleGerman:7-Aza-bicyclo 2.2.1 -heptan Derivate, deren Herstellung und Verwendung aufgrund ihrer Affinität für neuronale nikotinische Acetylcholin Rezeptoren[2007/46]
English:7-aza-bicyclo 2.2.1 -heptane derivatives, their preparation and use according to their affinity for neuronal nicotinic acetylcholine receptors[2007/46]
French:Dérivés de 7-aza-bicyclo 2.2.1 -heptane, leur préparation et utilisation sur la base d'affinité pour les recepteurs de l'acetylcholine nicotinique neuronaux[2007/46]
Former [1999/45]7-Aza-bicyclo[2.2.1]-heptan Derivate, deren Herstellung und Verwendung aufgrund ihrer Affinität für neuronale nikotinische Acetylchlolin Rezeptoren
Former [1999/45]7-aza-bicyclo[2.2.1]-heptane derivatives, their preparation and use according to their affinity for neuronal nicotinic acetylchloline receptors
Former [1999/45]Dérivés de 7-aza-bicyclo[2.2.1]-heptane, leur préparation et utilisation sur la base d'affinité pour les récepteurs de l'acetylchloline nicotinique neuronaux
Examination procedure12.04.1999Examination requested  [1999/45]
25.11.2002Despatch of a communication from the examining division (Time limit: M06)
03.06.2003Reply to a communication from the examining division
05.11.2003Despatch of a communication from the examining division (Time limit: M06)
20.08.2004Reply to a communication from the examining division
03.03.2005Despatch of a communication from the examining division (Time limit: M06)
22.12.2005Reply to a communication from the examining division
02.10.2007Application deemed to be withdrawn, date of legal effect  [2008/12]
05.11.2007Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2008/12]
Request for further processing for:22.12.2005Request for further processing filed
22.12.2005Full payment received (date of receipt of payment)
Request granted
13.01.2006Decision despatched
20.08.2004Request for further processing filed
20.08.2004Full payment received (date of receipt of payment)
Request granted
03.09.2004Decision despatched
Fees paidRenewal fee
27.01.2001Renewal fee patent year 03
10.01.2002Renewal fee patent year 04
22.01.2003Renewal fee patent year 05
06.02.2004Renewal fee patent year 06
29.01.2005Renewal fee patent year 07
13.01.2006Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
31.03.200709   M06   Not yet paid
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Documents cited:Search[X]WO9318037  (US HEALTH [US]) [X] 1-4,7,8 * claims 2,5,7 *;
 [DX]WO9422868  (UNIV VIRGINIA [US], et al) [DX] 1-3,7,8 * examples 25,40,44,54-56,60,63,64; claims 1-9,14-27,42-46 *;
 [DX]WO9503306  (DU PONT [US], et al) [DX] 1 * claims 1,5,10 *;
 [D]JPH0761940  (EISAI CO LTD) [D] * column 12 - column 13 * * column 16 * * column 18 - column 22 *;
 [DX]WO9507078  (CYTOMED INC [US], et al) [DX] 1-8 * claims 1-3,7-9,12-14; table I *;
 [DX]EP0657455  (EGYT GYOGYSZERVEGYESZETI GYAR [HU]) [DX] 1-4,7,8 * examples 12,19,26,33,42,48; claims 1-5,15,16 *;
 [DX]EP0664293  (DUPHAR INT RES [NL]) [DX] 1-4,7,8 * page 2, line 25 - line 26; example I; claims 1-4 *;
 [DX]WO9606093  (UNIV VIRGINIA [US], et al) [DX] 1-3,7,8 * figures 3,4,6; examples 25,40,44,54-56,60,81,82,84-90,93-95; claims 1-3,5-7,14-25,27-30,32-34 *;
 [PX]WO9846609  (ABBOTT LAB [US]) [PX] 1,5,7 * claims 1-8,13,14 *;
 [X]  - AKASAKA, K. ET AL., "Preparation of azabicycloheptane derivatives and their use as pharmaceuticals including analgesics", CHEMICAL ABSTRACTS, (19950911), vol. 123, no. 11, Database accession no. 132885k, page 130, column 1, XP002149521 [X] 1-4,7,8 * abstract *
 [A]  - HUISGEN R. ET AL., "1-Pyrrolines and 7-azabicyclo[2.2.1]heptane from azlactones and activated alkenes", CHEMISCHE BERICHTE, VERLAG CHEMIE GMBH. WEINHEIM, DE, (1970), vol. 103, no. 8, pages 2368 - 2387, XP000984022 [A] 1 * compounds 17, 19, 24, 26, 40 *
 [A]  - MARCHAND A.P. & ALLEN R.W., "Synthesis of 7-azanorbornene and N-methyl-7-azanorbornene", JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, US, (1975), vol. 40, no. 17, pages 2551 - 2552, XP000941118 [A] 9-11 * scheme I, compound 8 *

DOI:   http://dx.doi.org/10.1021/jo00905a037
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