EP1071745 - PROCESS FOR SYNTHESIZING COX-2 INHIBITORS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 10.06.2005 Database last updated on 02.09.2024 | Most recent event Tooltip | 05.06.2009 | Change - representative | published on 08.07.2009 [2009/28] | Applicant(s) | For all designated states Merck & Co., Inc. 126 East Lincoln Avenue Rahway, New Jersey 07065 / US | [N/P] |
Former [2001/05] | For all designated states MERCK & CO., INC. 126 East Lincoln Avenue Rahway, New Jersey 07065 / US | Inventor(s) | 01 /
CORLEY, Edward, G. 126 East Lincoln Avenue Rahway, NJ 07065 / US | 02 /
DAVIES, Ian, W. 126 East Lincoln Avenue Rahway, NJ 07065 / US | 03 /
LARSEN, Robert, D. 126 East Lincoln Avenue Rahway, NJ 07065 / US | 04 /
PYE, Philip, J. 126 East Lincoln Avenue Rahway, NJ 07065 / US | 05 /
ROSSEN, Kai 126 East Lincoln Avenue Rahway, NJ 07065 / US | [2001/05] | Representative(s) | Horgan, James Michael Frederic Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road, Harlow Essex CM20 2QR / GB | [N/P] |
Former [2009/28] | Horgan, James Michael Frederic Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow Essex CM20 2QR / GB | ||
Former [2001/05] | Horgan, James Michael Frederic Merck & Co., Inc., Terlings Park, Eastwick Road Harlow, Essex CM20 2QR / GB | Application number, filing date | 99918706.5 | 20.04.1999 | [2001/05] | WO1999US08645 | Priority number, date | US19980082888P | 24.04.1998 Original published format: US 82888 P | US19980085668P | 15.05.1998 Original published format: US 85668 P | [2001/05] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO9955830 | Date: | 04.11.1999 | Language: | EN | [1999/44] | Type: | A2 Application without search report | No.: | EP1071745 | Date: | 31.01.2001 | Language: | EN | The application published by WIPO in one of the EPO official languages on 04.11.1999 takes the place of the publication of the European patent application. | [2001/05] | Type: | B1 Patent specification | No.: | EP1071745 | Date: | 04.08.2004 | Language: | EN | [2004/32] | Search report(s) | International search report - published on: | US | 29.12.1999 | (Supplementary) European search report - dispatched on: | EP | 28.03.2002 | Classification | IPC: | C07C251/30, C07D213/61 | [2002/20] | CPC: |
C07D213/61 (EP,US);
C07D401/04 (KR);
A61P15/00 (EP);
A61P29/00 (EP);
A61P31/12 (EP);
A61P31/16 (EP);
A61P35/00 (EP);
A61P35/04 (EP);
A61P43/00 (EP);
C07C251/30 (EP,US)
(-)
|
Former IPC [2001/05] | C12N1/00 | Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, NL, PT, SE [2001/05] | Extension states | AL | 24.11.2000 | LT | 24.11.2000 | LV | 24.11.2000 | MK | 24.11.2000 | RO | 24.11.2000 | SI | 24.11.2000 | Title | German: | VERFAHREN ZUR SYNTHESE VON COX-2 INHIBITOREN | [2001/05] | English: | PROCESS FOR SYNTHESIZING COX-2 INHIBITORS | [2001/05] | French: | PROCEDE DE SYNTHESE D'INHIBITEURS DE COX-2 | [2001/05] | Entry into regional phase | 24.11.2000 | National basic fee paid | 24.11.2000 | Search fee paid | 24.11.2000 | Designation fee(s) paid | 24.11.2000 | Examination fee paid | Examination procedure | 22.11.1999 | Request for preliminary examination filed International Preliminary Examining Authority: US | 24.11.2000 | Examination requested [2001/05] | 29.07.2002 | Despatch of a communication from the examining division (Time limit: M04) | 27.11.2002 | Reply to a communication from the examining division | 20.12.2002 | Despatch of a communication from the examining division (Time limit: M04) | 03.03.2003 | Reply to a communication from the examining division | 10.04.2003 | Communication of intention to grant the patent | 20.10.2003 | Fee for grant paid | 20.10.2003 | Fee for publishing/printing paid | 20.10.2003 | Despatch of a communication from the examining division (Time limit: M06) | 26.04.2004 | Reply to a communication from the examining division | Opposition(s) | 06.05.2005 | No opposition filed within time limit [2005/30] | Fees paid | Renewal fee | 02.05.2001 | Renewal fee patent year 03 | 02.05.2002 | Renewal fee patent year 04 | 07.04.2003 | Renewal fee patent year 05 | 06.04.2004 | Renewal fee patent year 06 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A]GB1397869 (MERCK SHARP & DOHME) [A] 1-22* page 3, line 17 - line 20 *; | [X]WO9006913 (HOECHST AG [DE]) [X] 23,24,27 * claim 1 *; | [A]WO9803484 (MERCK FROSST CANADA INC [CA], et al) [A] 1-22 * claim 1 *; | [X] - PETRICH, S A ET AL, "The Reaction of a benzotriazole substituted vinamidinium salt with Grignard Reagents", HETEROCYCLES, (1994), vol. 39, no. 2, pages 623 - 637, XP000994905 [X] 23,24,27 * examples 2,7 * | [X] - BACHER E ET AL, "1-Acceptorsubstituierte Vinamidiniumsalze : Stabilität und Reaktivität", ZEITSCHRIFT FÜT NATURFORSCHUNG. SECTION B. A JOURNAL OF CHEMICAL SCIENCES, (1989), vol. 44, no. 7, pages 839 - 849, XP000994904 [X] 23-26 * examples 14A,14D,14F,14G,14K * | [X] - LIEPA A J, "A Synthesis of Hydroxylated Isoflavylium Salts and their Reduction Products.", AUSTRALIAN JOURNAL OF CHEMISTRY, (1981), vol. 34, no. 12, pages 2647 - 2655, XP000994913 [X] 23,24 * examples 5A-5D * | [X] - REICHARDT C ET AL, "SYNTHESEN MIT SUBSTITUIERTEN MALONDIALDEHYDEN, XIX DARSTELLUNG FLUORSUBSTITUIERTER CARBO- UND HETEROCYCLEN", JUSTUS LIEBIGS ANNALEN DER CHEMIE,VERLAG CHEMIE GMBH. WEINHEIM,DE, (1975), no. 3, ISSN 0075-4617, pages 470 - 483, XP000994953 [X] 23-25 * example 2 * DOI: http://dx.doi.org/10.1002/jlac.197519750311 | International search | [AP]US5861419 (DUBE DANIEL [CA], et al); | [A] - CHAN K. S., TSE A. K.-S., "SYNTHESIS OF BIS(TRIFLUOROMETHYL)-2,2'-BIPYRIDINES BY NICKEL CATALYSED HOMOCOUPLING REACTIONS.", Synthetic Communications, Taylor & Francis Inc., PHILADELPHIA, PA; US, PHILADELPHIA, PA; US, (19930101), vol. 23., no. 14., doi:10.1080/00397919308009849, ISSN 0039-7911, pages 1929 - 1934., XP002923054 DOI: http://dx.doi.org/10.1080/00397919308009849 | [A] - Uchida, Y. Kajita, R. Kawasaki, Y. Oae, S., "Unusual formation of 5-halo-2,2@?-bipyridyls by treatment of tris(2-pyridyl)phosphine derivatives with halogens", Tetrahedron Letters, Pergamon, GB, GB, (19950605), vol. 36, no. 23, doi:10.1016/0040-4039(95)00719-S, ISSN 0040-4039, pages 4077 - 4080, XP004027920 DOI: http://dx.doi.org/10.1016/0040-4039(95)00719-S | [A] - IWAMOTO K.-I., ET AL., "RING TRANSFORMATION OF FUSED PYRIDAZINES. IV. REACTION OF HALO-SUBSTITUTED FUSED PYRIDAZINES WITH YNAMINES.", Heterocycles: International Journal for Reviews and Communications in Heterocyclic Chemistry, Japan Institute of Heterocyclic Chemistry, JP, JP, (19960101), vol. 43., no. 01., ISSN 0385-5414, pages 199 - 204., XP002923055 |