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Extract from the Register of European Patents

EP About this file: EP1075284

EP1075284 - THE USE OF A VITAL DYE FOR FACILITATING SURGICAL PROCEDURES FOR VITREO-RETINAL SURGERY [Right-click to bookmark this link]
Status	Patent revoked Status updated on 17.12.2010 Database last updated on 11.04.2026
Most recent event Tooltip	03.06.2011	Lapse of the patent in a contracting state New state(s): CH, LI	published on 06.07.2011 [2011/27]
Applicant(s)	For all designated states Melles, Gerrit Reinold Jacob 's Landswerf 69 3063 GC Rotterdam / NL
	[2001/07]
Inventor(s)	01 / see applicant ...
	[2001/07]
Representative(s)	Prins, Adrianus Willem, et al V.O. Johan de Wittlaan 7 2517 JR Den Haag / NL
	[N/P]
Former [2001/07]	Prins, Adrianus Willem, et al Vereenigde, Nieuwe Parklaan 97 2587 BN Den Haag / NL
Application number, filing date	99921290.5	07.05.1999
	[2001/07]
	WO1999NL00283
Priority number, date	EP19980201542	08.05.1998 Original published format: EP 98201542
	EP19980202751	17.08.1998 Original published format: EP 98202751
	[2001/07]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO9958159
	Date:	18.11.1999
	Language:	EN
	[1999/46]
	Type:	A1 Application with search report
	No.:	EP1075284
	Date:	14.02.2001
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 18.11.1999 takes the place of the publication of the European patent application.
	[2001/07]
	Type:	B1 Patent specification
	No.:	EP1075284
	Date:	12.02.2003
	Language:	EN
	[2003/07]
Search report(s)	International search report - published on:	EP	18.11.1999
Classification	IPC:	A61K49/00, A61F9/007, A61P41/00	[2002/33]
	CPC:	A61K49/006 (EP,US); A61K49/00 (KR); A61P41/00 (EP)
	Former IPC [2001/07]	A61K49/00, A61F9/007
Designated contracting states	AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2001/07]
Extension states	AL	07.12.2000
	LT	07.12.2000
	LV	07.12.2000
	MK	07.12.2000
	RO	07.12.2000
	SI	07.12.2000
Title	German:	VERWENDUNG VON EINEM FARBSTOFF ZUM ERLEICHTERN DER AUGENNETZHAUTOPERATIONEN	[2001/07]
	English:	THE USE OF A VITAL DYE FOR FACILITATING SURGICAL PROCEDURES FOR VITREO-RETINAL SURGERY	[2001/07]
	French:	EMPLOI DE COLORANT VITAL POUR FACILITER DES INTERVENTIONS EN CHIRURGIE VITREO-RETINIENNE	[2001/07]
Entry into regional phase	07.12.2000	National basic fee paid
	07.12.2000	Designation fee(s) paid
	07.12.2000	Examination fee paid
Examination procedure	30.11.1999	Request for preliminary examination filed International Preliminary Examining Authority: EP
	07.12.2000	Examination requested [2001/07]
	12.02.2002	Despatch of a communication from the examining division (Time limit: M04)
	22.02.2002	Reply to a communication from the examining division
	24.07.2002	Communication of intention to grant the patent
	11.11.2002	Fee for grant paid
	11.11.2002	Fee for publishing/printing paid
Opposition(s)	Opponent(s)	01 20.06.2003 03.07.2003 ADMISSIBLE Industria Terapeutica Splendore Alfa Intes Via Fratelli Bandiera, 26 80026 CASORIA NA / IT Opponent's representative Prato, Roberto, et al, et al Studio Torta S.p.A. Via Viotti, 9 10121 Torino / IT
		02 11.11.2003 20.11.2003 ADMISSIBLE FLUORON GmbH Biberkopfweg 1 89231 Ulm / DE Opponent's representative Leißler-Gerstl, Gabriele Hoefer & Partner Patentanwälte mbB Pilgersheimer Strasse 20 81543 München / DE
		[N/P]
	Former [2009/48]
	Opponent(s)	01 20.06.2003 03.07.2003 ADMISSIBLE Industria Terapeutica Splendore Alfa Intes Via Fratelli Bandiera, 26 80026 CASORIA NA / IT Opponent's representative Prato, Roberto, et al, et al STUDIO TORTA Via Viotti 9 10121 Torino / IT
		02 11.11.2003 20.11.2003 ADMISSIBLE FLUORON GmbH Biberkopfweg 1 89231 Ulm / DE Opponent's representative Leissler-Gerstl, Gabriele Hoefer & Partner Patentanwälte Pilgersheimer Strasse 20 81543 München / DE
	Former [2009/46]
	Opponent(s)	01 20.06.2003 03.07.2003 ADMISSIBLE Industria Terapeutica Splendore Alfa Intes Via Fratelli Bandiera, 26 80026 CASORIA NA / IT Opponent's representative Prato, Roberto, et al, et al STUDIO TORTA Via Viotti 9 10121 Torino / IT
		02 11.11.2003 20.11.2003 ADMISSIBLE FLUORON GmbH Biberkopfweg 1 89231 Ulm / DE Opponent's representative Leissler-Gerstl, Gabriele Hoefer & Partner Patentanwälte Pilgersheimer Straße 20 D-81543 München / DE
	Former [2009/45]
	Opponent(s)	01 20.06.2003 03.07.2003 ADMISSIBLE Industria Terapeutica Splendore Alfa Intes Via Fratelli Bandiera, 26 80026 CASORIA NA / IT Opponent's representative Prato, Roberto, et al, et al STUDIO TORTA Via Viotti 9 10121 Torino / IT
		02 11.11.2003 20.11.2003 ADMISSIBLE FLUORON GmbH Biberkopfweg 1 89231 Ulm / DE
	Former [2008/45]
	Opponent(s)	01 20.06.2003 03.07.2003 ADMISSIBLE Industria Terapeutica Splendore Alfa Intes Via Fratelli Bandiera, 26 80026 CASORIA NA / IT Opponent's representative Prato, Roberto, et al, et al STUDIO TORTA Via Viotti 9 10121 Torino / IT
		02 11.11.2003 20.11.2003 ADMISSIBLE FLUORON GmbH Biberkopfweg 1 89231 Ulm / DE Opponent's representative Nöth, Heinz Patent Attorney, Arnulfstrasse 25 80335 München / DE
	Former [2004/02]
	Opponent(s)	01 20.06.2003 03.07.2003 ADMISSIBLE Industria Terapeutica Splendore Alfa Intes Via Fratelli Bandiera, 26 80026 CASORIA NA / IT Opponent's representative Prato, Roberto, et al, et al Studio Torta S.r.l., Via Viotti, 9 10121 Torino / IT
		02 11.11.2003 20.11.2003 ADMISSIBLE FLUORON GmbH Biberkopfweg 1 89231 Ulm / DE Opponent's representative Nöth, Heinz Patent Attorney, Arnulfstrasse 25 80335 München / DE
	Former [2003/33]
	Opponent(s)	01 20.06.2003 03.07.2003 ADMISSIBLE Industria Terapeutica Splendore Alfa Intes Via Fratelli Bandiera, 26 80026 CASORIA NA / IT Opponent's representative Prato, Roberto, et al, et al Studio Torta S.r.l., Via Viotti, 9 10121 Torino / IT
	deleted	Deletion: Legal effect of rejection of opposition [ N /P ]
	18.12.2003	Invitation to proprietor to file observations on the notice of opposition
	20.01.2004	Reply of patent proprietor to notice(s) of opposition
	05.11.2004	Despatch of a communication from the opposition division (Time limit: M04)
	14.03.2005	Reply to a communication from the opposition division
	13.12.2006	Date of oral proceedings
	01.02.2007	Despatch of minutes of oral proceedings
	01.02.2007	Date of despatch of rejection of opposition
	17.05.2010	Legal effect of revocation of patent [2011/03]
	17.05.2010	Despatch of communication that the patent will be revoked
Appeal following opposition	02.04.2007	Appeal received No. T0566/07
	30.05.2007	Statement of grounds filed
	17.05.2010	Result of appeal procedure: revocation of the patent
	17.05.2010	Date of oral proceedings
	25.05.2010	Minutes of the oral proceedings despatched
Fees paid	Renewal fee
	31.05.2001	Renewal fee patent year 03
	31.05.2002	Renewal fee patent year 04
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	CH	12.02.2003
	LI	12.02.2003
	MC	31.05.2009
	[2011/27]
Former [2010/06]	MC	31.05.2009
Cited in	International search	[X] LIU Z. H.: "Trypan blue staining on retinal ganglion cell of rat insulted in experimental high intraocular pressure", SOCIETY FOR NEUROSCIENCE ABSTACTS, vol. 18, no. 1-2, 1992, pages 1030, XP002082879 [X] 7-13 * abstract *
		[X] SPECTOR A. ET AL: "Brief photochemically induced oxidative insult causes irreversible lens damage and cataract I. Transparency and epithelial cell layer", EXP. EYE RES, vol. 60, no. 5, - May 1995 (1995-05-01), pages 471 - 481, XP002082880 [X] 7-13 * page 473, column 2, paragraph 3; figure 3; table 1 *
		[X] TANIUCHI O.: "Intraocular penetration of trypan blue and of colloidal carbon administered by intraTenon's capsulary injection", FOLIA OPHTHALMOL. JPN., 1981, 32/1 (343-350), JAPAN, XP002082881 [X] 7-13 * abstract *
		[T] SCHMIDT KL ET AL: "Ultrastructure of trypan blue induced ocular defects: I. Retina and lens.", TERATOLOGY, AUG 1983, 28 (1) P131-44, UNITED STATES, XP002082882 [T] 7-13 * see discussion paragraph 1;; table 1 * * page 143, column 1, paragraph 2 * DOI: http://dx.doi.org/10.1002/tera.1420280116
		[X] ATMACA L. ET AL: "Detection of subretinal neovascular membranes with indocyanine green videoangiography", JOURNAL FRANCAIS D'OPHTALMOLOGIE, 1997, 20/3 (189-194), France, XP002082883 [X] 7-13 * abstract * * page 194, paragraph 3 *
		[X] SAITO T: "[Vital staining of retina and uvea with trypan blue--particularly in comparison with neutral red staining (author's transl)]", NIPPON GANKA GAKKAI ZASSHI, JUL 10 1979, 83 (7) P659-68, JAPAN, XP002082884 [X] 7-13 * abstract * * page 665; table 1 *

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