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Extract from the Register of European Patents

EP About this file: EP1087954

EP1087954 - CYCLOALKYL-SUBSTITUTED ARYL-PIPERAZINES, PIPERIDINES AND TETRAHYDROPYRIDINES AS SEROTONERGIC AGENTS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  16.06.2006
Database last updated on 15.06.2024
Most recent event   Tooltip16.06.2006Application deemed to be withdrawnpublished on 19.07.2006  [2006/29]
Applicant(s)For all designated states
Wyeth
Five Giralda Farms
Madison, NJ 07940-0874 / US
[N/P]
Former [2002/25]For all designated states
Wyeth
Five Giralda Farms
Madison, New Jersey 07940-0874 / US
Former [2001/14]For all designated states
AMERICAN HOME PRODUCTS CORPORATION
Five Giralda Farms
Madison, New Jersey 07940-0874 / US
Inventor(s)01 / CHILDERS, Wayne, Everett
201 Riverwoods Drive
New Hope, PA 18938 / US
02 / KELLY, Michael, Gerard
790 Sandoval Place
Thousand Oaks, CA 91360 / US
03 / PALMER, Yvette, Latko
106 North Main Street
Yardley, PA 19067 / US
04 / PODLESNY, Edward, James
8196 Rabbit Run Road
New Tripoli, PA 18066 / US
 [2001/14]
Representative(s)Connelly, Michael John
C/o Patent Department Wyeth Laboratories Huntercombe Lane South Taplow
Maidenhead Berkshire SL6 0PH / GB
[N/P]
Former [2001/14]Connelly, Michael John
c/o Patent Department Wyeth Laboratories Huntercombe Lane South Taplow
Maidenhead Berkshire SL6 0PH / GB
Application number, filing date99928648.714.06.1999
[2001/14]
WO1999US13397
Priority number, dateUS1998009746315.06.1998         Original published format: US 97463
[2001/14]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO9965887
Date:23.12.1999
Language:EN
[1999/51]
Type: A1 Application with search report 
No.:EP1087954
Date:04.04.2001
Language:EN
The application published by WIPO in one of the EPO official languages on 23.12.1999 takes the place of the publication of the European patent application.
[2001/14]
Search report(s)International search report - published on:EP23.12.1999
ClassificationIPC:C07D295/12, C07D319/18, C07D209/08, A61K31/495
[2001/14]
CPC:
C07D295/13 (EP); A61P1/08 (EP); A61P13/08 (EP);
A61P25/22 (EP); A61P25/24 (EP); A61P25/28 (EP);
A61P35/00 (EP); A61P43/00 (EP); C07D209/08 (EP);
C07D211/22 (EP); C07D319/18 (EP) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   NL,   PT,   SE [2001/14]
Extension statesAL27.11.2000
LT27.11.2000
LV27.11.2000
RO27.11.2000
SI27.11.2000
TitleGerman:CYCLOALKYL-SUBSTITUIERTTE ARYL-PIPERAZINE, PIPERIDINE UND TETRAHYDROPYRIDINE ALS SEROTONERGISCHE AGENTIEN[2005/42]
English:CYCLOALKYL-SUBSTITUTED ARYL-PIPERAZINES, PIPERIDINES AND TETRAHYDROPYRIDINES AS SEROTONERGIC AGENTS[2001/14]
French:TETRAHYDROPYRIDINES, PIPERIDINES ET ARYL-PIPERAZINES A SUBSTITUTION CYCLOALKYLE, UTILISES EN TANT QU'AGENTS SEROTONINERGIQUES[2001/14]
Former [2001/14]CYCLOALKYL-SUBSTITUIERTTE ARYL-PIPERAZINE, PIPERIDINE UND TETRAHYDROPYRIDINE ALS SEROTONERGISCHE AGENTE
Entry into regional phase27.11.2000National basic fee paid 
27.11.2000Designation fee(s) paid 
27.11.2000Examination fee paid 
Examination procedure29.11.1999Request for preliminary examination filed
International Preliminary Examining Authority: EP
27.11.2000Examination requested  [2001/14]
23.05.2001Despatch of a communication from the examining division (Time limit: M06)
29.11.2001Reply to a communication from the examining division
11.02.2003Despatch of a communication from the examining division (Time limit: M07)
26.08.2003Reply to a communication from the examining division
29.07.2004Despatch of a communication from the examining division (Time limit: M04)
22.10.2004Reply to a communication from the examining division
15.09.2005Communication of intention to grant the patent
26.01.2006Application deemed to be withdrawn, date of legal effect  [2006/29]
01.03.2006Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2006/29]
Fees paidRenewal fee
05.06.2001Renewal fee patent year 03
07.06.2002Renewal fee patent year 04
04.06.2003Renewal fee patent year 05
04.06.2004Renewal fee patent year 06
06.06.2005Renewal fee patent year 07
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Cited inInternational search[Y]EP0737678  (AMERICAN HOME PROD [US]) [Y] 1-3,10 * page 2, line 7; claim - *;
 [Y]EP0506468  (LILLY CO ELI [US]) [Y] 1-3,10 * page 2, line 8; claim - *;
 [Y]WO9740038  (MERCK PATENT GMBH [DE], et al) [Y] 1-3,10 * abstract *;
 [Y]EP0395313  (AMERICAN HOME PROD [US], et al) [Y] 1-3,10 * page 2, line 14; claim - *;
 [Y]WO9601656  (WYETH JOHN & BROTHER LTD [GB], et al) [Y] 1-3,10 * abstract *;
 [Y]WO9533743  (WYETH JOHN & BROTHER LTD [GB], et al) [Y] 1-3,10 * abstract *;
 [Y]WO9421610  (WYETH JOHN & BROTHER LTD [GB], et al) [Y] 1-3,10 * abstract *;
 [Y]WO9311122  (WYETH JOHN & BROTHER LTD [GB]) [Y] 1-3,10 * abstract *;
 [Y]EP0512755  (WYETH JOHN & BROTHER LTD [GB]) [Y] 1-3,10 * abstract *;
 [A]EP0434561  (ADIR [FR]) [A] 1-3,10 * page 3, line 14 *;
 [A]WO9616949  (PF MEDICAMENT [FR], et al) [A] 1-3,10 * page 3, line 20 *;
 [A]WO9533729  (LUNDBECK & CO AS H [DK], et al) [A] 1-3,10 * abstract *;
 [A]WO9303016  (BOEHRINGER INGELHEIM ITALIA [IT]) [A] 1-3,10 * abstract *;
 [Y]  - I.A. CLIFFE ET AL., DRUGS OF THE FUTURE, (1993), vol. 18, no. 7, pages 631 - 642, XP002114577 [Y] 1-3,10 * page 636 - page 638 *
 [Y]  - GLENNON R A, "CONCEPTS FOR THE DESIGN OF 5-HT1A SEROTONIN AGONISTS AND ANTAGONISTS", DRUG DEVELOPMENT RESEARCH, (19920101), vol. 26, no. 3, ISSN 0272-4391, pages 251 - 274, XP000562325 [Y] 1-3,10 * page 262 - page 264 *

DOI:   http://dx.doi.org/10.1002/ddr.430260306
 [Y]  - SLEIGHT A J ET AL, "IDENTIFICATION OF 5-HYDROXYTRYPTAMINE1A RECEPTOR AGENTS USING A COMPOSITE PHARMACOPHORE ANALYSIS AND CHEMICAL DATABASE SCREENING", NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY, (19910101), vol. 343, pages 109 - 116, XP000650292 [Y] 1-3,10 * page 111 *

DOI:   http://dx.doi.org/10.1007/BF00168596
 [Y]  - D.L. NELSON, PHARMACOLOGY BIOCHEMISTRY & BEHAVIOR, (1991), vol. 40, pages 1041 - 1051, XP002114414 [Y] 1-3,10 * page 1048 *

DOI:   http://dx.doi.org/10.1016/0091-3057(91)90124-K
 [Y]  - GLENNON R A ET AL, "N-(PHTHALIMIDOALKYL) DERIVATIVES OF SEROTONERGIC AGENTS: A COMMON INTERACTION AT 5-HT1A SEROTONIN BINDING SITES?", JOURNAL OF MEDICINAL CHEMISTRY, (19890801), vol. 32, no. 8, ISSN 0022-2623, pages 1921 - 1926, XP000571455 [Y] 1-3,10 * page 1922 *

DOI:   http://dx.doi.org/10.1021/jm00128a039
 [Y]  - GLENNON R A ET AL, "STIMULUS PROPERTIES OF ARYLPIPERAZINES: NAN-190, A POTENTIAL 5 -HT1A SEROTONIN ANTAGONIST", DRUG DEVELOPMENT RESEARCH, (19890101), vol. 16, no. 2/04, ISSN 0272-4391, pages 335 - 343, XP000575594 [Y] 1-3,10 * page 341 *

DOI:   http://dx.doi.org/10.1002/ddr.430160227
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