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Extract from the Register of European Patents

EP About this file: EP1059285

EP1059285 - Process for the preparation of 1,3-diamino-2-propanol and 1,3-diamino-2-propanone derivatives [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  19.11.2004
Database last updated on 02.11.2024
Most recent event   Tooltip19.11.2004Application deemed to be withdrawnpublished on 05.01.2005  [2005/01]
Applicant(s)For all designated states
Johnson Matthey Pharmaceutical Materials Inc
25 Patton Road
Devens, Massachusetts 01432 / US
[2003/11]
Former [2003/06]For all designated states
Pharmaceutical Materials, Inc.
25 Patton Road
Devens, Massachusetts 01432 / US
Former [2001/44]For all designated states
Pharm-Eco Laboratories, Inc.
128 Spring Street
Lexington, MA 02173 / US
Former [2000/50]For all designated states
Pharm-Eco Laboratoires, Incorporated
128 Spring Street
Lexington, MA 02173 / US
Inventor(s)01 / Pal, Biman
172 Summer Street, No. 11
Watham, MA 02154 / US
02 / Ram, Siya
9 Grant Road
Winchester, MA 01890 / US
03 / Cai, Bing
1320 Cheryl Drive
Iselin, NJ 08830 / US
04 / Sachdeva, Yesh P.
324 Hayward Mill Road
Concord, MA 01742 / US
05 / Shim, Jaechul
21 Walden Square Road, No. 630
Cambridge, MA 02140 / US
06 / Zahr, Salah A.
37 Nylander Way
Acton, MA 01720 / US
07 / Al-Farhan, Emile
140 Chickering Road
Dedham, MA 02026 / US
08 / Gabriel, Richard
20 Blodgett Avenue
Swampscott, MA 01907 / US
 [2001/09]
Former [2000/50]01 / Pal, Biman
172 Summer Street, No. 11
Watham, MA 02154 / US
02 / Ram, Siya
9 Grant Road
Winchester, MA 01890 / US
03 / Cai, Bing
1320 Cheryl Drive
Iselin, NJ 08830 / US
04 / Sachdeva, Yesh P.
324 Hayward Mill Road
Concord, MA 01742 / US
05 / Shim, Jaechul
21 Walden Square Road, No. 630
Cambridge, MA 02140 / US
06 / Zahr, Salah A.
37 Nylander Way
Acton, MA 01720 / US
07 / Al-Farhan, Emile
140 Chickering Road
Dedham, MA 02026 / US
08 / Gabriel, Richard
60 Andrew Road
Swampscott, MA 01907 / US
Representative(s)Kirkham, Nicholas Andrew, et al
Graham Watt & Co. LLP
St. Botolph's House
7-9 St. Botolph's Road
Sevenoaks, Kent TN13 3AJ / GB
[N/P]
Former [2000/50]Kirkham, Nicholas Andrew, et al
Graham Watt & Co., Riverhead
Sevenoaks, Kent TN13 2BN / GB
Application number, filing date00202817.305.07.1995
[2000/50]
Priority number, dateUS1994027161907.07.1994         Original published format: US 271619
US1995047249607.06.1995         Original published format: US 472496
US1995048729407.06.1995         Original published format: US 487294
US1995048729607.06.1995         Original published format: US 487296
[2000/50]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP1059285
Date:13.12.2000
Language:EN
[2000/50]
Type: A3 Search report 
No.:EP1059285
Date:31.10.2001
[2001/44]
Search report(s)(Supplementary) European search report - dispatched on:EP17.09.2001
ClassificationIPC:C07C215/28, C07C269/06, C07C271/20, C07C271/22, C07D207/09, C07C271/16, C07C273/18, C07C275/14, C07C215/18
[2000/50]
CPC:
C07C271/16 (EP); C07C271/20 (EP)
Designated contracting statesAT,   BE,   CH,   DE,   DK,   ES,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2000/50]
TitleGerman:Verfahren zur Herstellung von 1,3-Diamino-2-propanol und 1,3-Diamino-2-propanon Derivativen[2000/50]
English:Process for the preparation of 1,3-diamino-2-propanol and 1,3-diamino-2-propanone derivatives[2000/50]
French:Procédé pour la préparation dérivés du 1,3-diamino-2-propanol et de 1,3-diamino-2-propanone[2000/50]
Examination procedure29.04.2002Examination requested  [2002/27]
17.01.2003Despatch of a communication from the examining division (Time limit: M06)
30.06.2003Reply to a communication from the examining division
16.07.2003Despatch of a communication from the examining division (Time limit: M06)
15.01.2004Reply to a communication from the examining division
20.02.2004Despatch of a communication from the examining division (Time limit: M04)
05.08.2004Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2005/01]
03.09.2004Application deemed to be withdrawn, date of legal effect  [2005/01]
Parent application(s)   TooltipEP95926176.9  / EP0769003
Fees paidRenewal fee
26.08.2000Renewal fee patent year 03
26.08.2000Renewal fee patent year 04
26.08.2000Renewal fee patent year 05
26.08.2000Renewal fee patent year 06
21.06.2001Renewal fee patent year 07
12.07.2002Renewal fee patent year 08
28.07.2003Renewal fee patent year 09
Penalty fee
Additional fee for renewal fee
31.07.200410   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XA]GB2200115  (SANDOZ LTD) [X] 7,9 * page 30 - page 31; examples 22C-E * * page 48 - page 51; example 55 * * page 51; examples 56A,,B * * page 55; example 57A * * page 57 - page 58; example 62 * [A] 1-6;
 [X]EP0389898  (HOFFMANN LA ROCHE [CH]) [X] 7 * example 16 *;
 [X]EP0580402  (SQUIBB & SONS INC [US]) [X] 9* examples 16B,27A,44A,185A,298A,379D *;
 [X]  - BARRISH J C ET AL, "AMINODIOL HIV PROTEASE INHIBITORS. 1. DESIGN, SYNTHESIS, AND PRELIMINARY SAR", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (1994), vol. 37, no. 12, ISSN 0022-2623, pages 1758 - 1768, XP001002509 [X] 9 * page 1759; figures 7A,,7B * * page 1760; table 1 * * page 1763 *

DOI:   http://dx.doi.org/10.1021/jm00038a005
 [X]  - ROSENBERG S H ET AL, "NOVEL RENIN INHIBITORS CONTAINING ANALOGUES OF STATINE RETRO-INVERTED AT THE C-TERMIN: SPECIFICITY AT THE P2 HISTIDINE SITE1,2", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, (19870701), vol. 30, no. 7, ISSN 0022-2623, pages 1224 - 1228, XP002027217 [X] 9 * page 1225; figures 3A,B * * page 1226, paragraph L - page 1227, paragraph 2 *

DOI:   http://dx.doi.org/10.1021/jm00390a018
 [X]  - D.S. HOLMES ET AL., "Synthesis and structure-activity relationships of a series of penicillin-derived HIV proteinase inhibitors containing a stereochemically unique peptide isostere", JOURNAL OF MEDICINAL CHEMISTRY, WASHINGTON US, (1993), vol. 36, pages 3129 - 3136, XP002176369 [X] 9 * page 3131: Scheme III, reaction e * * page 3135, column L, paragraph L - column R, paragraph 1 *

DOI:   http://dx.doi.org/10.1021/jm00073a012
 [X]  - W.J. GREENLEE ET AL., "Synthesis of an analogue of Tabtoxinine as a potential inhibitoe of D-alanine:D-alanine Ligase (ADP forming)", JOURNAL OF MEDICINAL CHEMISTRY, WASHINGTON US, (1989), vol. 32, pages 165 - 170, XP002176370 [X] 9 * page 167; figure 14 *

DOI:   http://dx.doi.org/10.1021/jm00121a030
 [A]  - WEI YUAN ET AL., "Development of selective tight-binding inhibitors of Leukotriene A4 hydrolase", JOURNAL OF MEDICINAL CHEMISTRY, WASHINGTON US, (1993), vol. 36, pages 211 - 220, XP002176371 [A] 1-6 * page 217, paragraph L - page 218, paragraph 1 * * page 213; figure 22 *

DOI:   http://dx.doi.org/10.1021/jm00054a004
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