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Extract from the Register of European Patents

EP About this file: EP1158045

EP1158045 - Culture conditions allowing to modulate the expression of CYP3A4 in CaCo2 cells [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  15.02.2003
Database last updated on 13.11.2024
Most recent event   Tooltip15.02.2003Application deemed to be withdrawnpublished on 02.04.2003  [2003/14]
Applicant(s)For all designated states
UNIVERSITE CATHOLIQUE DE LOUVAIN
Halles Universitaires Place de l'Université, 1
1348 Louvain-la-Neuve / BE
[N/P]
Former [2001/48]For all designated states
UNIVERSITE CATHOLIQUE DE LOUVAIN
Halles Universitaires Place de l'Université, 1
1348 Louvain-la-Neuve / BE
Inventor(s)01 / Schneider, Yves-Jacques
rue de la draisienne, 152
5500 Flamignoul / BE
02 / Burteau, Nathalie
rue des Glacières 47
6001 Marcinelle / BE
 [2001/48]
Representative(s)De Clercq, Ann G. Y.
De Clercq & Partners cvba Edgard Gevaertdreef 10 a
9830 Sint-Martens-Latem / BE
[N/P]
Former [2001/48]De Clercq, Ann
De Clercq, Brants & Partners cv., Edgard Gevaertdreef 10a
9830 Sint-Martens-Latem / BE
Application number, filing date00870108.817.05.2000
[2001/48]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP1158045
Date:28.11.2001
Language:EN
[2001/48]
Search report(s)(Supplementary) European search report - dispatched on:EP08.03.2001
ClassificationIPC:C12N5/08, G01N33/50
[2001/48]
CPC:
C12N5/0679 (EP); C12N5/0693 (EP); C12N2501/11 (EP);
C12N2501/33 (EP); C12N2501/39 (EP); C12N2503/02 (EP)
Designated contracting states(deleted) [2002/33]
Former [2001/48]AT,  BE,  CH,  CY,  DE,  DK,  ES,  FI,  FR,  GB,  GR,  IE,  IT,  LI,  LU,  MC,  NL,  PT,  SE 
TitleGerman:Kulturzustände die erlauben die Modulierung der Expression von CYP3A4 in CaCo2 Zellen[2001/48]
English:Culture conditions allowing to modulate the expression of CYP3A4 in CaCo2 cells[2001/48]
French:Conditions de culture permettant de moduler l'expression de CYP3A4 dans des cellules CaCo2[2001/48]
Biological materialThis application mentions deposited biological material, check the file for details
Examination procedure26.09.2000Loss of particular rights, legal effect: Claims
25.10.2000Despatch of communication of loss of particular rights: Claims {1}
29.05.2002Application deemed to be withdrawn, date of legal effect  [2003/14]
29.10.2002Despatch of communication that the application is deemed to be withdrawn, reason: examination fee not paid in time  [2003/14]
Fees paidPenalty fee
Penalty fee Rule 85a EPC 1973
26.07.2002AT   M01   Not yet paid
26.07.2002BE   M01   Not yet paid
26.07.2002CH   M01   Not yet paid
26.07.2002CY   M01   Not yet paid
26.07.2002DE   M01   Not yet paid
26.07.2002DK   M01   Not yet paid
26.07.2002ES   M01   Not yet paid
26.07.2002FI   M01   Not yet paid
26.07.2002FR   M01   Not yet paid
26.07.2002GB   M01   Not yet paid
26.07.2002GR   M01   Not yet paid
26.07.2002IE   M01   Not yet paid
26.07.2002IT   M01   Not yet paid
26.07.2002LU   M01   Not yet paid
26.07.2002MC   M01   Not yet paid
26.07.2002NL   M01   Not yet paid
26.07.2002PT   M01   Not yet paid
26.07.2002SE   M01   Not yet paid
Penalty fee Rule 85b EPC 1973
26.07.2002M01   Not yet paid
Additional fee for renewal fee
31.05.200203   M06   Not yet paid
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Documents cited:Search[A]US5856189  (WATKINS PAUL B [US], et al) [A] 1-10 * column W *;
 [X]  - FISHER JEANNINE M ET AL, "Midazolam metabolism by modified Caco-2 monolayers: Effects of extracellular protein binding.", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, (199905), vol. 289, no. 2, ISSN 0022-3565, pages 1143 - 1150, XP000982476 [X] 1,2,4-10 * the whole document *
 [A]  - SCHUETZ ERIN G ET AL, "Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.", MOLECULAR PHARMACOLOGY, (1996), vol. 49, no. 2, ISSN 0026-895X, pages 311 - 318, XP000906895 [A] 1-10 * the whole document *
 [DA]  - SCHMKIEDLIN-REN PHYLLSSA ET AL, "Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1-alpha,25-dihydroxyvitamin D-3.", MOLECULAR PHARMACOLOGY, (1997), vol. 51, no. 5, ISSN 0026-895X, pages 741 - 754, XP002161257 [DA] 1-10 * the whole document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.