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Extract from the Register of European Patents

EP About this file: EP1162980

EP1162980 - PYRIDOXINE COMPOUNDS IN THE TREATMENT OF CARDIOVASCULAR PATHOLOGIES [Right-click to bookmark this link]
Former [2001/51]	USE OF PYRIDOXINE COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR AND RELATED PATHOLOGIES
	[2003/36]
Status	No opposition filed within time limit Status updated on 24.12.2004 Database last updated on 05.05.2025
Most recent event Tooltip	24.12.2004	No opposition filed within time limit	published on 09.02.2005 [2005/06]
Applicant(s)	For all designated states Medicure Inc. 4-1200 Waverly Street Winnipeg Manitoba R3T 0P4 / CA
	For all designated states The University of Manitoba Room 202 Administration Building Winnipeg, Manitoba R3T 2N2 / CA
	[N/P]
Former [2001/51]	For all designated states Medicure Inc. 4-1200 Waverly Street Winnipeg, Manitoba R3T 0P4 / CA
	For all designated states THE UNIVERSITY OF MANITOBA Room 202 Administration Building Winnipeg, Manitoba R3T 2N2 / CA
Inventor(s)	01 / DHALLA, Naranjan, S. 52 River Pointe Drive Winnipeg, Manitoba R2M 5N6 / CA
	02 / SETHI, Rajat 3 Bunton Court Winnipeg, Manitoba R3X 1K4 / CA
	03 / DAKSHINAMURTI, Krishnamurti 934 Crestview Park Drive Winnipeg, Manitoba R2Y 0V7 / CA
	[2002/22]
Former [2001/51]	01 / DHALLA, Naranjan, S. 52 River Pointe Drive Winnipeg, Manitoba R2M 5N6 / CA
	02 / SETHI, Rajat 68 Sauve Crescent Winnipeg, Manitoba R2N 3K9 / CA
	03 / DAKSHINAMURTI, Krishnamurti 934 Crestview Park Drive Winnipeg, Manitoba R2Y 0V7 / CA
Representative(s)	Lotti, Giorgio c/o Ing. Barzanò & Zanardo Milano S.p.A. Corso Vittorio Emanuele II, 61 10128 Torino / IT
	[N/P]
Former [2001/51]	Lotti, Giorgio c/o Ing. Barzanò & Zanardo Milano S.p.A. Corso Vittorio Emanuele II, 61 10128 Torino / IT
Application number, filing date	00911153.5	22.03.2000
	[2001/51]
	WO2000IB00340
Priority number, date	US19990276280	25.03.1999 Original published format: US 276280
	[2001/51]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO0057863
	Date:	05.10.2000
	Language:	EN
	[2000/40]
	Type:	A2 Application without search report
	No.:	EP1162980
	Date:	19.12.2001
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 05.10.2000 takes the place of the publication of the European patent application.
	[2001/51]
	Type:	B1 Patent specification
	No.:	EP1162980
	Date:	18.02.2004
	Language:	EN
	[2004/08]
Search report(s)	International search report - published on:	EP	05.04.2001
Classification	IPC:	A61K31/675, A61K31/4415, A61P9/10	[2001/51]
	CPC:	A61K31/675 (EP,US); A61K31/4415 (EP,US); A61P43/00 (EP); A61P9/00 (EP); A61P9/04 (EP); A61P9/06 (EP); (+) A61P9/10 (EP); A61P9/12 (EP) (-)
Designated contracting states	AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2001/51]
Extension states	AL	Not yet paid
	LT	Not yet paid
	LV	Not yet paid
	MK	Not yet paid
	RO	Not yet paid
	SI	Not yet paid
Title	German:	PYRIDOXIN-DERIVATE IN DER BEHANDLUNG VON KARDIOVASKULÄREN BESCHWERDEN	[2003/36]
	English:	PYRIDOXINE COMPOUNDS IN THE TREATMENT OF CARDIOVASCULAR PATHOLOGIES	[2003/36]
	French:	DERIVES DE PYRIDOXINE DANS LE TRAITEMENT DE PATHOLOGIES CARDIOVASCULAIRES	[2003/36]
	Former [2001/51]	VERWENDUNG DER PYRIDOXIN-DERIVATEN ZUR BEHANDLUNG VON KARDIOVASKULÄREN UND VERWANDTEN BESCHWERDEN
	Former [2001/51]	USE OF PYRIDOXINE COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR AND RELATED PATHOLOGIES
	Former [2001/51]	TRAITEMENT DE PATHOLOGIES CARDIOVASCULAIRES ET APPARENTEES
Entry into regional phase	10.09.2001	National basic fee paid
	10.09.2001	Designation fee(s) paid
	10.09.2001	Examination fee paid
Examination procedure	06.10.2000	Request for preliminary examination filed International Preliminary Examining Authority: EP
	10.09.2001	Examination requested [2001/51]
	15.05.2002	Despatch of a communication from the examining division (Time limit: M04)
	16.09.2002	Reply to a communication from the examining division
	13.12.2002	Despatch of a communication from the examining division (Time limit: M02)
	11.02.2003	Reply to a communication from the examining division
	05.08.2003	Communication of intention to grant the patent
	04.12.2003	Fee for grant paid
	04.12.2003	Fee for publishing/printing paid
Opposition(s)	19.11.2004	No opposition filed within time limit [2005/06]
Fees paid	Renewal fee
	04.03.2002	Renewal fee patent year 03
	05.03.2003	Renewal fee patent year 04
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited in	International search	[X]FR5801M (BEAF) [X] 7 * the whole document *;
		[X]FR2034539 (SOC D ETUDES PROD CHIMIQUE [FR]) [X] 7 * page 1, lines 4-19 *;
		[PX]WO9953928 (UNIV MANITOBA [CA], et al) [PX] 1,7,9 * page 7, paragraph 3 * * page 5, paragraph 3 * * page 3, lines 1-3, paragraph 5 *;
		[X] - FOLSOM, AARON R. ET AL, "Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins The Atherosclerosis Risk in Communities (ARIC) study", CIRCULATION ( 1998 ), 98(3), 204-210, XP000965312 [X] 1,4-6,9,12-14 * page 209, column L, paragraph 3 *
		[X] - RIMM ET AL, "Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women", JAMA, (1998), vol. 279, no. 5, pages 359 - 364, XP000965325 [X] 1,4-7,9,11-14 * the whole document * DOI: http://dx.doi.org/10.1001/jama.279.5.359
		[X] - KUBYSHKIN V F, ET AL, "COMPARATIVE CHARACTERISTICS OF THE ARRHYTHMIC SYNDROME AND THE POSSIBILITY FOR ITS COENZYME CORRECTION IN DILATED AND HYPERTROPHIC CARDIOMYOPATHY", medline, (19000101), Database accession no. 90085046, XP002154067 [X] 1,3 * the whole document *
		[ ] - KUBYSHKIN, "[Comparative characteristics of the arrhythmic syndrome and the possibility for its coenzyme correction in dilated and hypertrophic cardiomyopathy]. Sravnitel'naia kharakteristika aritmicheskogo sindroma i vozmozhnosti ego kofermentnoi korrektsii pri dilatatsionnoi i gipertroficheskoi kardiomiopatii", TERAPEVTICHESKII ARKHIV, (1989), vol. 61, no. 9, pages 82 - 85, XP000965693
		[X] - LEVY H A ET AL, "Pyridoxine deficiency in congestive heart failure.", PROC SOC EXP BIOL MED, (1959 AUG-SEPT) 101 617-21., XP000965627 [X] 9,12-14 * page 621 * * page 618, column L * * page 620, column R *
		[X] - MENDELSOHN ET AL, "Hemodynamic and clinical effects of oral levodopa in children with congestive heart failure", JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, (19970701), vol. 30, pages 237 - 242, XP000965154 [X] 9,14 * page 238, column R, paragraph 1 * DOI: http://dx.doi.org/10.1016/S0735-1097(97)00109-5
		[A] - AYBAK ET AL, "Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension", ARZNEIMITTEL FORSCHUNG, (19951201), vol. 45, no. 12, pages 1271 - 1273, XP000961002 [A] 7 * page 1272, column L, paragraph 2 * * page 1271, column L, paragraph 1 *
		[A] - MANORE M M ET AL, "CHANGES IN PLASMA PYRIDOXAL PHOSPHATE PLP IN DIABETIC D HYPERTENSIVE HTN AND HYPERTENSIVE -DIABETIC HTN-D ME FED A CONSTANT VITAMIN B-6 B6 DIET.", 75TH ANNUAL MEETING OF THE FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY, ATLANTA, GEORGIA, USA, APRIL 21-25, 1991. FASEB (FE AM SOC EXP BIOL) J. (1991) 5 (4), A586., XP000961053 [A] 7 * the whole document *
		[A] - MULVANEY D A ET AL, "Electrocardiographic changes in vitamin B6 deficient rats.", CARDIOVASCULAR RESEARCH, (1979 SEP) 13 (9) 506-13., XP000965568 [A] 1,3-6,9,11-14 * the whole document * DOI: http://dx.doi.org/10.1093/cvr/13.9.506
		[A] - BHAGAVAN H N ET AL, "Effect of postweanling pyridoxine deficiency on growth and concentration of the coenzyme pyridoxal -5'-phosphate in heart, kidneys, lungs, and adrenals in rats.", PEDIATRIC RESEARCH, (1976 AUG) 10 (8) 730-2., XP000965630 [A] 1,3-6 * page 731 *
		[A] - TAKUMA ET AL, "Combination therapy of infantile spasms with high-dose pyridoxal phosphate and low-dose corticotropin", JOURNAL OF CHILD NEUROLOGY, (19960101), vol. 11, pages 35 - 40, XP000965567 [A] 7,8 * the whole document *
		[A] - VIDRIO H, "Interaction with pyridoxal as a possible mechanism of hydralazine hypotension", JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, (19900101), vol. 15, pages 150 - 156, XP000965625 [A] 7,8 * the whole document *

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