EP1165800 - MITOMYCIN BIOSYNTHETIC GENE CLUSTER [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 13.05.2005 Database last updated on 01.01.2025 | Most recent event Tooltip | 13.05.2005 | Application deemed to be withdrawn | published on 29.06.2005 [2005/26] | Applicant(s) | For all designated states REGENTS OF THE UNIVERSITY OF MINNESOTA University Gateway, Suite 600 200 Oak Street SE Minneapolis, MN 55455 / US | For all designated states Sherman, David H. 2248 Drew Avenue South St. Louis Park, MN 55416 / US | For all designated states Mao, Yingqing 1393 North Cleveland Avenue St. Paul, MN 55108 / US | For all designated states Varoglu, Mustafa 2120 Como Avenue 3 St. Paul, MN 55108 / US | For all designated states He, Min 2004 Knapp Avenue St. Paul, MN 55108 / US | For all designated states Sheldon, Paul C. 2959 King James Way Fitchburg, Wi 53719-1674 / US | [N/P] |
Former [2002/01] | For all designated states REGENTS OF THE UNIVERSITY OF MINNESOTA 600 University Gateway, 200 Oak Street SE Minneapolis, MN 55455-2070 / US | ||
For all designated states Sherman, David H. 2248 Drew Avenue South St. Louis Park, MN 55416 / US | |||
For all designated states Mao, Yingqing 1393 North Cleveland Avenue St. Paul, MN 55108 / US | |||
For all designated states Varoglu, Mustafa 2120 Como Avenue 3 St. Paul, MN 55108 / US | |||
For all designated states He, Min 2004 Knapp Avenue St. Paul, MN 55108 / US | |||
For all designated states Sheldon, Paul C. 2959 King James Way Fitchburg, Wi 53719-1674 / US | Inventor(s) | 01 /
SHERMAN, David, H. 2248 Drew Avenue South St. Louis Park, MN 55416 / US | 02 /
MAO, Yingqing 1393 North Cleveland Avenue St. Paul, MN 55108 / US | 03 /
VAROGLU, Mustafa 2120 Como Avenue 3 St. Paul, MN 55108 / US | 04 /
HE, Min 2004 Knapp Avenue St. Paul, MN 55108 / US | 05 /
SHELDON, Paul, C. 2959 King James Way Fitchburg, WI 53719-1674 / US | [2002/01] | Representative(s) | Schüssler, Andrea Kanzlei Huber & Schüssler Truderinger Strasse 246 81825 München / DE | [N/P] |
Former [2002/01] | Schüssler, Andrea, Dr. Kanzlei Huber & Schüssler Truderinger Strasse 246 81825 München / DE | Application number, filing date | 00917855.9 | 10.03.2000 | [2002/01] | WO2000US06394 | Priority number, date | US19990266965 | 12.03.1999 Original published format: US 266965 | [2002/01] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO0053737 | Date: | 14.09.2000 | Language: | EN | [2000/37] | Type: | A2 Application without search report | No.: | EP1165800 | Date: | 02.01.2002 | Language: | EN | The application published by WIPO in one of the EPO official languages on 14.09.2000 takes the place of the publication of the European patent application. | [2002/01] | Search report(s) | International search report - published on: | EP | 21.12.2000 | Classification | IPC: | C12N15/52, C12N9/00, C12N9/02, C12N9/10, C12N9/12, C12N9/14, C12N9/88, C12N1/21, C07D487/14, C07D519/00, C12P17/18 | [2002/01] | CPC: |
C12N9/93 (EP,US);
C07K14/36 (EP,US);
C12N15/52 (EP,US);
C12N9/0004 (EP,US);
C12N9/10 (EP,US);
C12N9/1007 (EP,US);
C12N9/12 (EP,US);
C12N9/14 (EP,US);
C12N9/88 (EP,US);
| Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2002/01] | Extension states | AL | Not yet paid | LT | Not yet paid | LV | Not yet paid | MK | Not yet paid | RO | Not yet paid | SI | Not yet paid | Title | German: | MITOMYCIN-BIOSYNTHESE GENGRUPPE | [2002/01] | English: | MITOMYCIN BIOSYNTHETIC GENE CLUSTER | [2002/01] | French: | GROUPE DE GENES BIOSYNTHETIQUES DESTINES A LA MITOMYCINE | [2002/01] | Entry into regional phase | 12.10.2001 | National basic fee paid | 12.10.2001 | Designation fee(s) paid | 12.10.2001 | Examination fee paid | Examination procedure | 12.10.2000 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 12.10.2001 | Amendment by applicant (claims and/or description) | 12.10.2001 | Examination requested [2002/01] | 19.07.2004 | Despatch of a communication from the examining division (Time limit: M04) | 30.11.2004 | Application deemed to be withdrawn, date of legal effect [2005/26] | 05.01.2005 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2005/26] | Fees paid | Renewal fee | 22.03.2002 | Renewal fee patent year 03 | 24.03.2003 | Renewal fee patent year 04 | 22.03.2004 | Renewal fee patent year 05 | Penalty fee | Additional fee for renewal fee | 31.03.2005 | 06   M06   Not yet paid |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [X]WO9509926 (UNIV MINNESOTA [US], et al) [X] 1,4,5,11,34-37,39,41 * page 4 - page 6; figure 14; examples 1,3,6,9; claims 3-5 * * page 10 - page 15 * * page 19 - page 21 *; | [X]US4395558 (KASAI MASAJI [US], et al) [X] 17-19 * column 1 - column 5 *; | [X]WO9807868 (CIBA GEIGY AG [CH], et al) [X] 29-31 * abstract * * page 5 - page 18 *; | [XD] - KIM C-G ET AL., "3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics", JOURNAL OF BIOLOGICAL CHEMISTRY, (19980313), vol. 273, no. 11, pages 6030 - 6040, XP002145258 [XD] 1,2,4-6,11,22,23,29,31,34,35,37-39 * the whole document * DOI: http://dx.doi.org/10.1074/jbc.273.11.6030 | [X] - XUE Y ET AL, "A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, (19981013), vol. 95, no. 21, ISSN 0027-8424, pages 12111 - 12116, XP002117399 [X] 21,25,27 * the whole document * DOI: http://dx.doi.org/10.1073/pnas.95.21.12111 | [X] - M BIERMAN ET AL, "Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp", GENE,NL,ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, (19920701), vol. 116, no. 1, ISSN 0378-1119, pages 43 - 49, XP002116076 [X] 32,33 * the whole document * DOI: http://dx.doi.org/10.1016/0378-1119(92)90627-2 | [X] - AUGUST P R ET AL, "Inducible synthesis of the Mitomycin C resistance gene product (MCRA) from Streptomyces lavendulae", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES,GB,ELSEVIER SCIENCE PUBLISHERS, BARKING, (19961010), vol. 175, no. 1, ISSN 0378-1119, pages 261 - 267, XP004043324 [X] 40,41 * abstract * * page 266, paragraph 2 * DOI: http://dx.doi.org/10.1016/0378-1119(96)00172-2 | [A] - RUAN X ET AL., "A second type-I PKS cluster isolated from Streptomyces hygroscopicus ATCC 29253, a rapamycin-producing strain", GENE, (1997), vol. 203, pages 1 - 9, XP002145259 [A] 24 * abstract * * page 6 - page 7 * DOI: http://dx.doi.org/10.1016/S0378-1119(97)00450-2 | [PXD] - MAO Y ET AL., "Molecular characterization and analysisof the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces levendulae NRRL 2564", CHEMISTRY AND BIOLOGY, (19990323), vol. 6, pages 251 - 263, XP000924816 [PXD] 1-19,21-44 * the whole document * * see especially page 263, bottom of right hand column * DOI: http://dx.doi.org/10.1016/S1074-5521(99)80040-4 |