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Extract from the Register of European Patents

EP About this file: EP1171133

EP1171133 - R-HYDROXYNEFAZODONE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  27.04.2007
Database last updated on 03.10.2024
Most recent event   Tooltip07.08.2009Lapse of the patent in a contracting state
New state(s): CY		published on 09.09.2009  [2009/37]
Applicant(s)For all designated states
Sepracor Inc.
84 Waterford Drive
Marlborough, MA 01752 / US
[2006/22]
Former [2002/03]For all designated states
Sepracor Inc.
111 Locke Drive
Marlborough, MA 01752 / US
Inventor(s)01 / BARBERICH, Timothy, J.
40 Elm Street
Concord, MA 01742 / US
02 / RUBIN, Paul, D.
37 Greystone Lane
Sudbury, MA 01752 / US
03 / YELLE, William, E.
20 Ernie's Drive
Littleton, MA 01460 / US
 [2002/03]
Representative(s)Wallace, Sheila Jane, et al
Marks & Clerk LLP
15 Fetter Lane
London EC4A 1BW / GB
[N/P]
Former [2002/03]Wallace, Sheila Jane, et al
Lloyd Wise, Tregear & Co., Commonwealth House, 1-19 New Oxford Street
London WC1A 1LW / GB
Application number, filing date00921896.707.04.2000
[2002/03]
WO2000US09373
Priority number, dateUS19990128479P09.04.1999         Original published format: US 128479 P
[2002/03]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0061128
Date:19.10.2000
Language:EN
[2000/42]
Type: A2 Application without search report 
No.:EP1171133
Date:16.01.2002
Language:EN
The application published by WIPO in one of the EPO official languages on 19.10.2000 takes the place of the publication of the European patent application.
[2002/03]
Type: B1 Patent specification 
No.:EP1171133
Date:21.06.2006
Language:EN
[2006/25]
Search report(s)International search report - published on:EP16.08.2001
ClassificationIPC:A61K31/496, A61P25/24
[2006/04]
CPC:
A61K31/496 (EP,US); A61P25/00 (EP); A61P25/06 (EP);
A61P25/18 (EP); A61P25/20 (EP); A61P25/22 (EP);
A61P25/24 (EP); A61P29/00 (EP); A61P3/04 (EP);
C07D249/12 (EP,US) (-)
Former IPC [2002/03]A61K31/496, A61P25/00, A61P3/04, A61P25/24, A61P25/20, A61P25/22, A61P25/06
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2002/03]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:R-HYDROXYNEFAZODON[2002/03]
English:R-HYDROXYNEFAZODONE[2002/03]
French:HYDROXY-NEFAZODONE R[2002/03]
Entry into regional phase07.11.2001National basic fee paid 
07.11.2001Designation fee(s) paid 
07.11.2001Examination fee paid 
Examination procedure08.11.2000Request for preliminary examination filed
International Preliminary Examining Authority: EP
07.11.2001Examination requested  [2002/03]
22.01.2002Amendment by applicant (claims and/or description)
18.03.2004Despatch of a communication from the examining division (Time limit: M06)
26.08.2004Reply to a communication from the examining division
12.01.2006Communication of intention to grant the patent
29.03.2006Fee for grant paid
29.03.2006Fee for publishing/printing paid
Opposition(s)22.03.2007No opposition filed within time limit [2007/22]
Fees paidRenewal fee
12.04.2002Renewal fee patent year 03
14.04.2003Renewal fee patent year 04
15.04.2004Renewal fee patent year 05
13.04.2005Renewal fee patent year 06
17.03.2006Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT21.06.2006
BE21.06.2006
CH21.06.2006
CY21.06.2006
FI21.06.2006
IT21.06.2006
LI21.06.2006
NL21.06.2006
DK21.09.2006
SE21.09.2006
GR22.09.2006
PT21.11.2006
[2009/37]
Former [2008/19]AT21.06.2006
BE21.06.2006
CH21.06.2006
FI21.06.2006
IT21.06.2006
LI21.06.2006
NL21.06.2006
DK21.09.2006
SE21.09.2006
GR22.09.2006
PT21.11.2006
Former [2007/35]AT21.06.2006
BE21.06.2006
CH21.06.2006
FI21.06.2006
IT21.06.2006
LI21.06.2006
NL21.06.2006
DK21.09.2006
SE21.09.2006
PT21.11.2006
Former [2007/22]AT21.06.2006
BE21.06.2006
CH21.06.2006
FI21.06.2006
LI21.06.2006
NL21.06.2006
DK21.09.2006
SE21.09.2006
PT21.11.2006
Former [2007/19]AT21.06.2006
BE21.06.2006
CH21.06.2006
FI21.06.2006
LI21.06.2006
NL21.06.2006
SE21.09.2006
PT21.11.2006
Former [2007/13]AT21.06.2006
BE21.06.2006
CH21.06.2006
FI21.06.2006
LI21.06.2006
SE21.09.2006
PT21.11.2006
Former [2007/12]AT21.06.2006
CH21.06.2006
FI21.06.2006
LI21.06.2006
SE21.09.2006
PT21.11.2006
Former [2007/03]AT21.06.2006
CH21.06.2006
FI21.06.2006
LI21.06.2006
SE21.09.2006
Former [2006/52]AT21.06.2006
FI21.06.2006
SE21.09.2006
Former [2006/51]FI21.06.2006
SE21.09.2006
Former [2006/48]SE21.09.2006
Cited inInternational search[A]US4338317  (TEMPLE JR DAVIS L, et al) [A] 1,19-26 * abstract * * column 1, line 5 - line 11 * * column 2, line 64 - column 3, line 13 * * column 3, line 66 - column 4, line 21 * * column 6, line 46 - column 7, line 25 * * claims 1-3 *;
 [DX]US4613600  (GAMMANS RICHARD E [US], et al) [DX] 1,19-27 * abstract * * column 1, line 5 - line 12 * * column 2, line 44 - column 4, line 18 * * column 4, line 51 - line 64 * * column 6, line 64 - column 7, line 50 * * example 1 * * claim - *;
 [X]US5256664  (MAYOL ROBERT F [US], et al) [X] 1 * page 1, line 27 - line 46 * * column 3, line 7 - line 61 *;
 [X]US5788986  (DODMAN NICHOLAS H [US]) [X] 23-25,27 * abstract * * column 12, line 32 - line 67 * * column 14, line 1 - line 19 * * column 21, line 1 - line 6 * * table 2 * * column 23, line 33 - line 63 * * column 24, line 11 - line 37 * * claims 1,6 *;
 [X]  - CYR M ET AL, "NEFAZODONE: ITS PLACE AMONG ANTIDEPRESSANTS", ANNALS OF PHARMACOTHERAPY,XX,XX, (19960901), vol. 30, no. 9, ISSN 1060-0280, pages 1006 - 1012, XP000613004 [X] 1 * page 1006, column 1, paragraph 3 * * page 1007, column 1, paragraph 4 - paragraph 5 *
 [DX]  - MALIK, KEMAL, "Nefazodone: structure, mode of action and pharmacokinetics", J. PSYCHOPHARMACOL., (1996), vol. 10 (Suppl. 1), pages 1 - 4, XP000861812 [DX] 1 * abstract * * page 3, column 1, paragraph 4 * * page 3, column 2, paragraph 2 *
 [A]  - NACCA ANGELO; GUISO GIOVANNA; FRACASSO CLAUDIA; CERVO LUIGI; CACCIA SILVIO, "Brain-to-blood partition and in vivo inhibition of 5-hydroxytryptamine reuptake and quipazine-mediated behaviour of nefazodone and its main active metabolites in rodents.", BRITISH JOURNAL OF PHARMACOLOGY, (199812), vol. 125, no. 7, pages 1617 - 1623, XP000861819 [A] 1,20,21,23,24 * page 1617, column 1, paragraph 2 * * page 1618, column 1, paragraph 2 - paragraph 3 * * page 1619, column 2, paragraph 3 * * figure 3 *

DOI:   http://dx.doi.org/10.1038/sj.bjp.0702251
 [A]  - MONTGOMERY S A, "EFFICACY OF NEFAZODONE IN THE TREATMENT OF DEPRESSION", JOURNAL OF PSYCHOPHARMACOLOGY,GB,OXFORD UNIVERSITY PRESS, (1996), vol. 10, no. SUPPL. 01, ISSN 0269-8811, pages 5 - 10, XP000613043 [A] 1,19-22 * abstract * * page 5, column 1, paragraph 1 * * page 9, column 2, paragraph 2 - paragraph 4 *
 [A]  - GREENE D S ET AL, "Clinical pharmacokinetics of nefazodone.", CLINICAL PHARMACOKINETICS, (1997 OCT) 33 (4) 260-75. REF: 51, XP000911986 [A] * abstract * * page 261, column 1, paragraph 2 * * figures 1,2 * * page 269, column 2, paragraph 2 - page 273, column 1, paragraph 2 * * page 273, column 2, paragraph 1 - paragraph 3 *
 [A]  - SCHMIDER J ET AL, "Inhibition of cytochrome P450 by nefazodone in vitro: studies of dextromethorphan O- and N-demethylation.", BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, (1996 APR) 41 (4) 339-43., XP000861967 [A] * abstract * * page 339, column 1, paragraph 1 - page 340, column 1, paragraph 1 * * page 342, column 1, paragraph 2 *

DOI:   http://dx.doi.org/10.1046/j.1365-2125.1996.30512.x
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.