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Extract from the Register of European Patents

EP About this file: EP1159457

EP1159457 - T CELL RECEPTOR VBETA - DBETA - JBETA) SEQUENCE AND METHODS FOR ITS DETECTION [Right-click to bookmark this link]
Former [2001/49]T CELL RECEPTOR VBETA BETA-JBETA) SEQUENCE AND METHODS FOR ITS DETECTION
[2010/37]
StatusNo opposition filed within time limit
Status updated on  09.09.2011
Database last updated on 19.07.2024
Most recent event   Tooltip24.05.2013Lapse of the patent in a contracting state
New state(s): CY		published on 26.06.2013  [2013/26]
Applicant(s)For all designated states
BAYLOR COLLEGE OF MEDICINE
One Baylor Plaza
Houston, TX 77030 / US
[2001/49]
Inventor(s)01 / ZHANG, Jingwu, Z.
2219 Parkview Lane
Missouri City, TX 77459 / US
 [2001/49]
Representative(s)Walton, Seán Malcolm, et al
Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[N/P]
Former [2010/44]Walton, Seán Malcolm, et al
Mewburn Ellis LLP 33 Gutter Lane London
EC2V 8AS / GB
Former [2005/06]Walton, Seán Malcolm
Mewburn Ellis LLP York House, 23 Kingsway
London WC2B 6HP / GB
Former [2001/49]De Clercq, Ann, et al
De Clercq, Brants & Partners cv., Edgard Gevaertdreef 10a
9830 Sint-Martens-Latem / BE
Application number, filing date00922309.022.02.2000
[2001/49]
WO2000US40006
Priority number, dateUS19990121311P23.02.1999         Original published format: US 121311 P
[2001/49]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0050641
Date:31.08.2000
Language:EN
[2000/35]
Type: A1 Application with search report 
No.:EP1159457
Date:05.12.2001
Language:EN
The application published by WIPO in one of the EPO official languages on 31.08.2000 takes the place of the publication of the European patent application.
[2001/49]
Type: B1 Patent specification 
No.:EP1159457
Date:03.11.2010
Language:EN
[2010/44]
Search report(s)International search report - published on:US31.08.2000
(Supplementary) European search report - dispatched on:EP05.10.2004
ClassificationIPC:C12Q1/68, C07H21/02, C07H21/04, A01N37/18, A61K38/00
[2001/49]
CPC:
C12Q1/6883 (EP,KR,US); A61P1/04 (EP); A61P19/02 (EP);
A61P21/00 (EP); A61P21/04 (EP); A61P25/00 (EP);
A61P27/02 (EP); A61P29/00 (EP); A61P3/10 (EP);
A61P37/00 (EP); A61P37/02 (EP); A61P37/06 (EP);
A61P43/00 (EP); A61P5/14 (EP); A61P9/10 (EP);
C12Q2600/158 (EP,KR,US) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2001/49]
Extension statesAL20.08.2001
LT20.08.2001
LV20.08.2001
MK23.09.2001
RO20.08.2001
SI20.08.2001
TitleGerman:T-ZELLREZEPTOR Vb-Db-Jb-SEQUENZ UND VERFAHREN FÜR IHREN NACHWEIS[2001/49]
English:T CELL RECEPTOR VBETA - DBETA - JBETA) SEQUENCE AND METHODS FOR ITS DETECTION[2010/37]
French:SEQUENCE VBETA-DBETA-JBETA DU RECEPTEUR DE LEUCOCYTES T ET PROCEDES DE SA DETECTION[2001/49]
Former [2001/49]T CELL RECEPTOR VBETA BETA-JBETA) SEQUENCE AND METHODS FOR ITS DETECTION
Entry into regional phase20.08.2001National basic fee paid 
20.08.2001Search fee paid 
20.08.2001Designation fee(s) paid 
20.08.2001Examination fee paid 
Examination procedure20.09.2000Request for preliminary examination filed
International Preliminary Examining Authority: US
20.08.2001Examination requested  [2001/49]
24.12.2004Amendment by applicant (claims and/or description)
03.01.2008Despatch of a communication from the examining division (Time limit: M04)
13.05.2008Reply to a communication from the examining division
07.04.2010Communication of intention to grant the patent
06.08.2010Fee for grant paid
06.08.2010Fee for publishing/printing paid
Opposition(s)04.08.2011No opposition filed within time limit [2011/41]
Fees paidRenewal fee
13.02.2002Renewal fee patent year 03
28.02.2003Renewal fee patent year 04
26.02.2004Renewal fee patent year 05
14.02.2005Renewal fee patent year 06
14.02.2006Renewal fee patent year 07
27.02.2007Renewal fee patent year 08
22.02.2008Renewal fee patent year 09
26.02.2009Renewal fee patent year 10
16.02.2010Renewal fee patent year 11
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT03.11.2010
BE03.11.2010
CY03.11.2010
DK03.11.2010
FI03.11.2010
IT03.11.2010
NL03.11.2010
SE03.11.2010
GR04.02.2011
ES14.02.2011
IE22.02.2011
LU22.02.2011
CH28.02.2011
LI28.02.2011
MC28.02.2011
PT03.03.2011
[2013/26]
Former [2013/25]AT03.11.2010
BE03.11.2010
DK03.11.2010
FI03.11.2010
IT03.11.2010
NL03.11.2010
SE03.11.2010
GR04.02.2011
ES14.02.2011
IE22.02.2011
LU22.02.2011
CH28.02.2011
LI28.02.2011
MC28.02.2011
PT03.03.2011
Former [2012/08]AT03.11.2010
BE03.11.2010
DK03.11.2010
FI03.11.2010
IT03.11.2010
NL03.11.2010
SE03.11.2010
GR04.02.2011
ES14.02.2011
IE22.02.2011
CH28.02.2011
LI28.02.2011
MC28.02.2011
PT03.03.2011
Former [2012/03]AT03.11.2010
BE03.11.2010
DK03.11.2010
FI03.11.2010
IT03.11.2010
NL03.11.2010
SE03.11.2010
GR04.02.2011
ES14.02.2011
CH28.02.2011
LI28.02.2011
MC28.02.2011
PT03.03.2011
Former [2011/48]AT03.11.2010
BE03.11.2010
DK03.11.2010
FI03.11.2010
NL03.11.2010
SE03.11.2010
GR04.02.2011
ES14.02.2011
CH28.02.2011
LI28.02.2011
MC28.02.2011
PT03.03.2011
Former [2011/45]AT03.11.2010
BE03.11.2010
DK03.11.2010
FI03.11.2010
NL03.11.2010
SE03.11.2010
GR04.02.2011
ES14.02.2011
MC28.02.2011
PT03.03.2011
Former [2011/40]AT03.11.2010
BE03.11.2010
DK03.11.2010
FI03.11.2010
NL03.11.2010
SE03.11.2010
GR04.02.2011
ES14.02.2011
PT03.03.2011
Former [2011/35]AT03.11.2010
BE03.11.2010
FI03.11.2010
NL03.11.2010
SE03.11.2010
GR04.02.2011
ES14.02.2011
PT03.03.2011
Former [2011/31]AT03.11.2010
FI03.11.2010
NL03.11.2010
SE03.11.2010
GR04.02.2011
PT03.03.2011
Former [2011/24]FI03.11.2010
NL03.11.2010
SE03.11.2010
PT03.03.2011
Documents cited:Search[Y]WO9618105  (HARVARD COLLEGE [US]) [Y] 4,5,8-10,14,15,17,18,20,21 * abstract * * page 18, line 22 *;
 [Y]  - STEINMAN L, "Specific motifs in T cell receptor VbetaDbetaJbeta gene sequences in multiple sclerosis in brain", BEHRING INSTITUT MITTEILUNGEN, (1994), vol. 94, pages 148 - 157, XP008035925 [Y] 4,5,8-10,14,15,17,18,20,21 * the whole document *
International search[X]  - "OLIGONUCLEOTIDES", BOEHRINGER MANNHEIM BIOCHEMICALS CATALOG, XX, XX, XX, (19930101), page 87, XP002928181
 [AP]  - HONG ET AL., "A Common TCR V-D-J Sequence in Vbetaa13.1 T Cells Recognizing an Immunodominant Peptide of Myeling Basic protein in multiple Sclerosis", JOURNAL OF IMMUNOLOGY,, (199909), vol. 163, no. 6, pages 3530 - 3538, XP002928174
 [A]  - KOZOVSKA ET AL., "T Cell Recognition Motifs of an Immunodominant Peptide of Myelin Basic Protein in Patients with Multiple Sclerosis: Structural Requirements and Clinical Implications", EUROPEAN JOURNAL OF IMMUNOLOGY,, (199806), vol. 28, no. 6, pages 1894 - 1901, XP002928182

DOI:   http://dx.doi.org/10.1002/(SICI)1521-4141(199806)28:06<1894::AID-IMMU1894>3.0.CO;2-W
 [A]  - ZANG ET AL., "Restricted TCR Valpha Gene Rearrangements in T Cells Recognizing an Immunodominant Peptide of Myeling Basic Protein in DR2 Patients with Multiple Sclerosis", INTERNATIONAL IMMUNOLOGY,, (199807), vol. 10, no. 7, pages 991 - 998, XP002928183

DOI:   http://dx.doi.org/10.1093/intimm/10.7.991
 [A]  - ZHANG J., "Emerging Therapeutic Targets in Multiple Sclerosis: Suppression and Elimination of Myelin-Autoreactive T-Lymphocytes", CAPLUS,
    [ ] - EMERGING THERAPEUTIC TARGETS,, (1998), vol. 2, no. 2, pages 137 - 156
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.