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Extract from the Register of European Patents

EP About this file: EP1187924

EP1187924 - SUBSTRATE TRAPPING PROTEIN TYROSINE PHOSPHATASES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  06.06.2008
Database last updated on 02.11.2024
Most recent event   Tooltip06.06.2008Application deemed to be withdrawnpublished on 09.07.2008  [2008/28]
Applicant(s)For all designated states
COLD SPRING HARBOR LABORATORY
Nichols Building, One Bungtown Road
Cold Spring Harbor, NY 11724 / US
[N/P]
Former [2002/12]For all designated states
Cold Spring Harbor Laboratory
Nichols Building, One Bungtown Road
Cold Spring Harbor, NY 11724 / US
Inventor(s)01 / TONKS, Nicholas, K.
3 Arrowhead Place
Huntington, NY 11732 / US
02 / ZHANG, Shao-Hui
13415 Bavarian Drive
San Diego, CA 92129 / US
 [2002/12]
Representative(s)Lock, Graham James, et al
Fry Heath & Spence LLP
Unit A, Faraday Court
Faraday Road
Crawley, West Sussex RH10 9PU / GB
[N/P]
Former [2002/12]Lock, Graham James, et al
Fry Heath & Spence, The Old College, 53 High Street
Horley, Surrey RH6 7BN / GB
Application number, filing date00937706.024.05.2000
[2002/12]
WO2000US14211
Priority number, dateUS19990137319P03.06.1999         Original published format: US 137319 P
US1999033457516.06.1999         Original published format: US 334575
[2002/12]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0075339
Date:14.12.2000
Language:EN
[2000/50]
Type: A1 Application with search report 
No.:EP1187924
Date:20.03.2002
Language:EN
The application published by WIPO in one of the EPO official languages on 14.12.2000 takes the place of the publication of the European patent application.
[2002/12]
Search report(s)International search report - published on:EP14.12.2000
ClassificationIPC:C12N15/52, C12N9/16, C12N15/62, A61K38/00, C12N15/11, G01N33/566
[2002/12]
CPC:
C12N9/16 (EP); A61P35/00 (EP); A61P43/00 (EP);
C07K2319/02 (EP)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2002/12]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:SUBSTRAT FANGENDE PROTEIN TYROSIN PHOSPHATASE[2002/12]
English:SUBSTRATE TRAPPING PROTEIN TYROSINE PHOSPHATASES[2002/12]
French:PROTEINE-TYROSINE-PHOSPHATASES DE PIEGEAGE DE SUBSTRATS[2002/12]
Entry into regional phase03.01.2002National basic fee paid 
03.01.2002Designation fee(s) paid 
03.01.2002Examination fee paid 
Examination procedure13.12.2000Request for preliminary examination filed
International Preliminary Examining Authority: EP
03.01.2002Examination requested  [2002/12]
13.02.2002Amendment by applicant (claims and/or description)
10.06.2003Despatch of a communication from the examining division (Time limit: M08)
22.01.2004Reply to a communication from the examining division
14.08.2007Despatch of a communication from the examining division (Time limit: M04)
28.12.2007Application deemed to be withdrawn, date of legal effect  [2008/28]
30.01.2008Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2008/28]
Fees paidRenewal fee
14.05.2002Renewal fee patent year 03
13.05.2003Renewal fee patent year 04
13.05.2004Renewal fee patent year 05
19.05.2005Renewal fee patent year 06
30.05.2006Renewal fee patent year 07
30.05.2007Renewal fee patent year 08
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Cited inInternational search[YD]WO9804712  (COLD SPRING HARBOR LAB) [YD] 1-54 * the whole document *;
 [Y]  - J.W. ECKSTEIN ET AL., "Identification of an essential acidic residue in Cdc25 protein phosphatase and a general three-dimensional model for a core region in protein phosphatases.", PROTEIN SCIENCE, (199601), vol. 5, no. 1, pages 5 - 12, XP002051424 [Y] 1-54 * figure 4 *
 [YD]  - A.J. FLINT ET AL., "Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases", PROC. NATL. ACAD. SCI. USA, (199703), vol. 94, pages 1680 - 1685, XP002051429 [YD] 1-54 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.94.5.1680
 [Y]  - A.J. GARTON ET AL., "Identification of p130cas as a substrate for teh cytosolic protein tyrosine phosphatase PTP-PEST.", MOLECULAR AND CELLULAR BIOLOGY, (199611), vol. 16, no. 11, pages 6408 - 6418, XP002051430 [Y] 1-54 * the whole document *
 [Y]  - B.L. SEELY ET AL., "Protein tyrosine phosphatase 1B interacts with the activated insulin receptor.", DIABETES, (199610), vol. 45, no. 10, pages 1379 - 1385, XP002051432 [Y] 1-54 * the whole document *

DOI:   http://dx.doi.org/10.2337/diabetes.45.10.1379
 [Y]  - LAMONTAGNE K.R. JR. ET AL, "Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of rat-1 fibroblasts and promotes differentiation of K562 cells.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (24 NOV 1998) 95/24 (14094-14099)., XP000861906 [Y] 1-54 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.95.24.14094
 [YD]  - TIGANIS T. ET AL, "Epidermal growth factor receptor and the adaptor protein p52(Shc) are specific substrates of T-cell protein tyrosine phosphatase.", MOLECULAR AND CELLULAR BIOLOGY, (1998) 18/3 (1622-1634)., XP000861959 [YD] 1-54 * the whole document *
 [PX]  - ZHANG S.-H. ET AL, "Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein - tyrosine phosphatase PTPH1.", JOURNAL OF BIOLOGICAL CHEMISTRY, (18 JUN 1999) 274/25 (17806-17812)., XP000938707 [PX] 1-54 * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.274.25.17806
 [AD]  - Q. YANG ET AL., "Cloning and expression of PTP-PEST.", THE JOURNAL OF BIOLOGICAL CHEMISTRY, (19930325), vol. 268, no. 9, pages 6622 - 6628, XP002034265 [AD] * figure 2 *
 [A]  - F. LIU ET AL., "Direct binding of a proline-rich region of protein tyrosine phosphatase 1B to the Src Homology 3 Domain of p130 cas", THE JOURNAL OF BIOLOGICAL CHEMISTRY, (19961206), vol. 271, no. 49, pages 31290 - 31295, XP002051433 [A] * the whole document *

DOI:   http://dx.doi.org/10.1074/jbc.271.49.31290
 [A]  - MYERS M.P. ET AL, "The lipid phosphatase activity of PTEN is critical for its tumor supresso function.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, (10 NOV 1998) 95/23 (13513-13518)., XP000861905

DOI:   http://dx.doi.org/10.1073/pnas.95.23.13513
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.