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Extract from the Register of European Patents

EP About this file: EP1274431

EP1274431 - 10,11-DIFLUOROMETHYLENEDIOXYCAMPTOTHECIN COMPOUNDS WITH TOPOISOMERASE I INHIBITION [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  30.04.2004
Database last updated on 25.09.2024
Most recent event   Tooltip23.10.2009Change - representativepublished on 25.11.2009  [2009/48]
Applicant(s)For all designated states
RESEARCH TRIANGLE INSTITUTE
Office of Research Contracs, 3040 Cornwallis Road
Research Triangle Park, NC 27709 / US
For all designated states
Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton, NJ 08543 / US
[N/P]
Former [2008/37]For all designated states
RESEARCH TRIANGLE INSTITUTE
Office of Research Contracs, 3040 Cornwallis Road
Research Triangle Park, NC 27709 / US
For all designated states
Bristol-Myers Squibb Company
Route 206 and Province Line Road
Princeton NJ 05843-4000 / US
Former [2003/03]For all designated states
RESEARCH TRIANGLE INSTITUTE
Office of Research Contracs, 3040 Cornwallis Road
Research Triangle Park, NC 27709 / US
For all designated states
Bristol-Myers Squibb Company
Route 206 & Provinceline Road
Princeton, NJ 08543-4000 / US
Inventor(s)01 / WALL, Monroe E.
Villa 406, Carolina Meadows
Chapel Hill, NC 27514 / US
02 / WANI, Manuskh C.
2801 Legion Avenue
Durham, NC 27707 / US
03 / MANIKUMAR, Govindarajan
8008 Selfridge Court
Raleigh, NC 27615 / US
04 / BALASUBRAMANIAN, Neelakantan
26 Horsebarn Lane
Madison, CT 06443 / US
05 / VYAS, Dolatrai
19 Thames Way
Madison, CT 06443 / US
 [2003/03]
Representative(s)Ilgart, Jean-Christophe, et al
BREVALEX
95, Rue d'Amsterdam
75378 Paris Cedex 8 / FR
[N/P]
Former [2009/48]Ilgart, Jean-Christophe, et al
Brevalex 3, rue du Docteur Lancereaux
75008 Paris / FR
Former [2003/03]Ilgart, Jean-Christophe, et al
BREVALEX, 3, rue du Docteur Lancereaux
75008 Paris / FR
Application number, filing date00939455.214.06.2000
[2003/03]
WO2000US15034
Priority number, dateUS1999047475829.12.1999         Original published format: US 474758
[2003/03]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0149291
Date:12.07.2001
Language:EN
[2001/28]
Type: A1 Application with search report 
No.:EP1274431
Date:15.01.2003
Language:EN
The application published by WIPO in one of the EPO official languages on 12.07.2001 takes the place of the publication of the European patent application.
[2003/03]
Search report(s)International search report - published on:US12.07.2001
(Supplementary) European search report - dispatched on:EP13.03.2003
ClassificationIPC:A61K31/4741, A61K31/4745, C07D491/22, A61K31/435
[2003/18]
CPC:
C07D491/22 (EP,KR,US); A61K31/4738 (KR); A61P35/00 (EP);
A61P35/02 (EP); A61P43/00 (EP)
Former IPC [2003/03]A61K31/4741, A61K31/4745, C07D491/22
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2003/03]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:10,11-DIFLUOROMETHYLENDIOXYCAMTOTHECIN-VERBINDUNGEN MIT TOPOISOMERASE-I INHIBITION[2003/03]
English:10,11-DIFLUOROMETHYLENEDIOXYCAMPTOTHECIN COMPOUNDS WITH TOPOISOMERASE I INHIBITION[2003/03]
French:COMPOSES 10, 11-DIFLUOROMETHYLENEDIOXYCAMPTOTHECINE AVEC INHIBITION DE TOPOISOMERASE I[2003/03]
Entry into regional phase08.07.2002National basic fee paid 
08.07.2002Search fee paid 
08.07.2002Designation fee(s) paid 
08.07.2002Examination fee paid 
Examination procedure24.07.2001Request for preliminary examination filed
International Preliminary Examining Authority: US
11.07.2002Examination requested  [2003/03]
31.07.2003Despatch of a communication from the examining division (Time limit: M04)
11.12.2003Application deemed to be withdrawn, date of legal effect  [2004/25]
16.01.2004Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2004/25]
Fees paidRenewal fee
26.06.2002Renewal fee patent year 03
12.06.2003Renewal fee patent year 04
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Documents cited:Search[X]WO9719085  (RES TRIANGLE INST [US]) [X] 1-10* claim 1 *;
 [X]US5646159  (WALL MONROE E [US], et al) [X] 1-10 * claim 1 *
International search[X]  - BRANGI M. ET AL., "Camptothecin resistance: Role of the ATP-binding cassette(ABC), mitoxantrone-resistance half-transporter(MXR) and potential for glucuronidation in MXR-expressing cells", CANCER RES.,, (19991201), vol. 59, pages 5938 - 5946, XP002930493
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.