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Extract from the Register of European Patents

EP About this file: EP1200073

EP1200073 - SELECTIVE iGluR 5? RECEPTOR ANTAGONISTS FOR THE TREATMENT OF MIGRAINE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  16.11.2007
Database last updated on 14.09.2024
Most recent event   Tooltip16.11.2007No opposition filed within time limitpublished on 19.12.2007  [2007/51]
Applicant(s)For all designated states
ELI LILLY AND COMPANY
Lilly Corporate Center
Indianapolis, IN 46285 / US
[N/P]
Former [2007/02]For all designated states
ELI LILLY AND COMPANY
Lilly Corporate Center
Indianapolis IN 46285 / US
Former [2002/18]For all designated states
ELI LILLY AND COMPANY
Lilly Corporate Center
Indianapolis, Indiana 46285 / US
Inventor(s)01 / BLEAKMAN, David
720 Eagle Creek Court
Zionsville, IN 46077 / US
02 / CHAPPELL, Amy Suzon
9040 Woodacre Boulevard, South Drive
Indianapolis, IN 46234 / US
03 / FILLA, Sandra, Ann
1680 Williamsburg Lane
Franklin, IN 46131 / US
04 / JOHNSON, Kirk, Willis
1177 Helford Lane
Carmel, IN 46032 / US
05 / ORNSTEIN, Paul, Leslie
10441 Bosahan Court
Carmel, IN 46032 / US
 [2002/18]
Representative(s)Suarez-Miles, Ana Sanchiz, et al
Eli Lilly and Company Limited
Lilly Research Centre
Erl Wood Manor
Sunninghill Road
Windlesham, Surrey GU20 6PH / GB
[N/P]
Former [2007/08]Suarez-Miles, Ana Sanchiz, et al
Eli Lilly and Company Limited Lilly Research Centre Erl Wood Manor Sunninghill Road
Windlesham, Surrey GU20 6PH / GB
Former [2006/23]Kingsbury, Oliver William, et al
Eli Lilly and Company Limited Lilly Research Centre Erl Wood Manor Sunninghill Road
Windlesham, Surrey GU20 6PH / GB
Former [2002/18]Pritchard, Judith, et al
Eli Lilly and Company Limited Lilly Research Centre Erl Wood Manor
Windlesham, Surrey GU20 6PH / GB
Application number, filing date00944671.727.06.2000
[2002/18]
WO2000US16297
Priority number, dateUS19990142485P06.07.1999         Original published format: US 142485 P
US19990151165P27.08.1999         Original published format: US 151165 P
[2002/18]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO0101972
Date:11.01.2001
Language:EN
[2001/02]
Type: A2 Application without search report 
No.:EP1200073
Date:02.05.2002
Language:EN
The application published by WIPO in one of the EPO official languages on 11.01.2001 takes the place of the publication of the European patent application.
[2002/18]
Type: B1 Patent specification 
No.:EP1200073
Date:10.01.2007
Language:EN
[2007/02]
Search report(s)International search report - published on:EP06.12.2001
ClassificationIPC:A61K31/00, A61K31/4725, A61K31/472, A61K31/5377, C07D401/06, C07D413/06, A61P25/06
[2002/18]
CPC:
C07D401/06 (EP,US); A61K31/4725 (EP,KR,US); A61K31/00 (EP,US);
A61K31/472 (EP,US); A61P21/02 (EP); A61P25/00 (EP);
A61P25/04 (EP); A61P25/06 (EP); A61P25/14 (EP);
A61P25/16 (EP); A61P25/18 (EP); A61P25/22 (EP);
A61P25/24 (EP); A61P25/28 (EP); A61P25/30 (EP);
A61P27/02 (EP); A61P43/00 (EP) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2002/18]
Extension statesAL06.06.2002
LT06.06.2002
LV06.06.2002
MK06.06.2002
RO06.06.2002
SI06.06.2002
TitleGerman:SELEKTIVE IGLUR5 REZEPTORANTAGONISTEN ZUR BEHANDLUNG DER MIGRÄNE[2002/18]
English:SELECTIVE iGluR 5? RECEPTOR ANTAGONISTS FOR THE TREATMENT OF MIGRAINE[2002/18]
French:ANTAGONISTES SELECTIFS DU RECEPTEUR iGluR 5? UTILISES DANS LE TRAITEMENT DE LA MIGRAINE[2002/18]
Entry into regional phase06.02.2002National basic fee paid 
06.06.2002Designation fee(s) paid 
06.06.2002Examination fee paid 
Examination procedure08.01.2001Request for preliminary examination filed
International Preliminary Examining Authority: EP
06.06.2002Examination requested  [2002/32]
18.10.2004Amendment by applicant (claims and/or description)
22.12.2004Despatch of a communication from the examining division (Time limit: M04)
24.03.2005Reply to a communication from the examining division
28.12.2005Communication of intention to grant the patent
08.05.2006Fee for grant paid
08.05.2006Fee for publishing/printing paid
Opposition(s)11.10.2007No opposition filed within time limit [2007/51]
Fees paidRenewal fee
01.07.2002Renewal fee patent year 03
30.06.2003Renewal fee patent year 04
30.06.2004Renewal fee patent year 05
30.06.2005Renewal fee patent year 06
30.06.2006Renewal fee patent year 07
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Cited inInternational search[Y]US5356902  (ORNSTEIN PAUL L [US]) [Y] 1,2,4,9,10,12 * column 3 * * column 5, line 10 - line 30 *;
 [YD]US5670516  (ARNOLD M BRIAN [US], et al) [YD] 1,2,4,5,9,10,12,13 * column 2 * * column 3, line 40 * * column 7, line 21 - line 27 * * see column 45 compounds 7-9 *;
 [A]US5767117  (MOSKOWITZ MICHAEL A [US]) [A] 8 * column A * * column 3, line 59 - line 67 ** column 4, line 1 - line 9 *;
 [YDA]WO9845270  (LILLY CO ELI [US], et al) [YD] 1,2,4,9,10,12 * the whole document * [A] 3,11;
 [E]WO0102367  (LILLY CO ELI [US], et al) [E] 1-3,9-11 * the whole document *;
 [Y]  - PROCTER ET AL, "Possible role of GluR5 glutamate receptors in spinal nociceptive processing in the anaesthetized rat", JOURNAL OF PHYSIOLOGY,XX,XX, (199711), vol. 504P, ISSN 0022-3751, pages 101P - 102P, XP002108296 [Y] 1,4,9,10,12 * the whole document *
 [Y]  - NIKAM ET AL., "The search for AMPA/Gly(N) receptor antagonists", DRUGS FUTURE, (1999), vol. 24, no. 10, pages 1107 - 1124, XP000997758 [Y] 1,4,5,9,10,12,13 * page 1109, column R * * page 1110, column L *

DOI:   http://dx.doi.org/10.1358/dof.1999.024.10.858631
 [YA]  - O'NEILL MJ ET AL, "Decahydroisoquinolines: novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia.", NEUROPHARMACOLOGY, OCT-NOV 1998, 37 (10-11) P1211-22, ENGLAND, XP000997636 [Y] 1,4,5,9,10,12,13 * the whole document * [A] 2,3,11

DOI:   http://dx.doi.org/10.1016/S0028-3908(98)00134-8
 [YA]  - PROCTER MJ ET AL, "Actions of kainate and AMPA selective glutamate receptor ligands on nociceptive processing in the spinal cord.", NEUROPHARMACOLOGY, OCT-NOV 1998, 37 (10-11) P1287-97, ENGLAND, XP000997628 [Y] 1,2,4,9,10,12 * the whole document * [A] 3,11

DOI:   http://dx.doi.org/10.1016/S0028-3908(98)00136-1
 [A]  - BLEAKMAN D., "Kainate receptor pharmacology and physiology", CELLULAR AND MOLECULAR LIFE SCIENCES_(_CELL. MOL. LIFE SCI._), 56/7-8 (558-566), Switzerland, XP000990931 [A] 1,9,10 * page 559, column R, paragraph 3 * * page 562, column R, paragraph 2 *

DOI:   http://dx.doi.org/10.1007/s000180050453
 [YDA]  - SIMMONS RM ET AL, "Kainate GluR5 receptor subtype mediates the nociceptive response to formalin in the rat.", NEUROPHARMACOLOGY, 1998, 37 (1) P25-36, ENGLAND, XP000997629 [YD] 1,2,9,10 * the whole document * [A] 3,11

DOI:   http://dx.doi.org/10.1016/S0028-3908(97)00188-3
 [A]  - MITSIKOSTAS DD ET AL, "Non-NMDA glutamate receptors modulate capsaicin induced c-fos expression within trigeminal nucleus caudalis.", MEDLINE, US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US, Database accession no. 10003939, URL: DIALOG, XP002165715 [A] 1,9,10 * abstract *
    [ ] - BRITISH JOURNAL OF PHARMACOLOGY, JUN 1999, 127 (3) P623-30, ENGLAND
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.