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Extract from the Register of European Patents

EP About this file: EP1196027

EP1196027 - CORTICOTROPIN RELEASING FACTOR RECEPTOR 2 DEFICIENT MICE AND USES THEREOF [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  24.02.2006
Database last updated on 24.01.2025
Most recent event   Tooltip24.02.2006Application deemed to be withdrawnpublished on 12.04.2006  [2006/15]
Applicant(s)For all designated states
RESEARCH DEVELOPMENT FOUNDATION
402 North Division Street
Carson City, Nevada 89703 / US
[N/P]
Former [2002/16]For all designated states
RESEARCH DEVELOPMENT FOUNDATION
402 North Division Street
Carson City Nevada 89703 / US
Inventor(s)01 / LEE, Kuo-Fen
13269 Mango Drive
Del Mar, CA 92014 / US
02 / BALE, Tracy, L.
7780 Prairie Shadow Road
San Diego, CA 92126 / US
03 / SMITH, George, W.
3051 Gould Road
Onondaga, MI 49264-9728 / US
04 / VALE, Wylie
1643 Valdes
La Jolla, CA 92307 / US
 [2002/22]
Former [2002/16]01 / LEE, Kuo-Fen
13269 Mango Drive
Del Mar, CA 92014 / US
02 / BALE, Tracy, L.
7780 Prairie Shadow Road
San Diego, CA 92126 / US
03 / SMITH, George, W.
530 Beacon Lake Drive 7
Mason, MI 48854 / US
04 / VALE, Wylie
1643 Valdes
La Jolla, CA 92307 / US
Representative(s)Campbell, Joanne Marie
Stevens, Hewlett & Perkins
1 St. Augustine's Place
Bristol BS1 4UD / GB
[N/P]
Former [2005/26]Heaton, Joanne Marie
Stevens, Hewlett & Perkins 1 St. Augustine's Place
Bristol BS1 4UD / GB
Former [2002/16]Wilkinson, Stephen John
Stevens, Hewlett & Perkins 1 St. Augustine's Place
Bristol BS1 4UD / GB
Application number, filing date00948702.614.07.2000
[2002/16]
WO2000US19371
Priority number, dateUS19990144261P15.07.1999         Original published format: US 144261 P
[2002/16]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO0105222
Date:25.01.2001
Language:EN
[2001/04]
Type: A1 Application with search report 
No.:EP1196027
Date:17.04.2002
Language:EN
The application published by WIPO in one of the EPO official languages on 25.01.2001 takes the place of the publication of the European patent application.
[2002/16]
Search report(s)International search report - published on:US25.01.2001
(Supplementary) European search report - dispatched on:EP05.11.2004
ClassificationIPC:A01K67/027
[2002/16]
CPC:
A01K67/0276 (EP,US); A01K67/027 (KR); C07K14/723 (EP,US);
C12N15/8509 (EP,US); A01K2217/075 (EP,US); A01K2227/105 (EP,US);
A01K2267/03 (EP,US); A01K2267/0356 (EP,US); A61K38/00 (EP,US) (-)
Designated contracting statesAT,   BE,   CH,   CY,   DE,   DK,   ES,   FI,   FR,   GB,   GR,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   SE [2002/16]
Extension statesALNot yet paid
LTNot yet paid
LVNot yet paid
MKNot yet paid
RONot yet paid
SINot yet paid
TitleGerman:MÄUSE, DENEN DER "CORTICOTROPIN-RELEASING"-FAKTOR-REZEPTOR 2 FEHLTUND IHRE VERWENDUNGEN[2002/16]
English:CORTICOTROPIN RELEASING FACTOR RECEPTOR 2 DEFICIENT MICE AND USES THEREOF[2002/16]
French:SOURIS A DEFICIENCE DE RECEPTEUR 2 DU FACTEUR DE LIBERATION DE LA CORTICOTROPINE, ET UTILISATIONS CORRESPONDANTES[2002/16]
Entry into regional phase15.01.2002National basic fee paid 
15.01.2002Search fee paid 
15.01.2002Designation fee(s) paid 
15.01.2002Examination fee paid 
Examination procedure22.01.2001Request for preliminary examination filed
International Preliminary Examining Authority: US
15.01.2002Examination requested  [2002/16]
08.03.2002Loss of particular rights, legal effect: Claims
21.06.2002Despatch of communication of loss of particular rights: Claims {1}
21.03.2005Despatch of a communication from the examining division (Time limit: M06)
01.10.2005Application deemed to be withdrawn, date of legal effect  [2006/15]
09.11.2005Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2006/15]
Fees paidRenewal fee
22.07.2002Renewal fee patent year 03
23.07.2003Renewal fee patent year 04
22.07.2004Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
31.07.200506   M06   Not yet paid
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Documents cited:Search[X]WO9534651  (NEUROCRINE BIOSCIENCES INC [US], et al) [X] 1,6 * page 20, line 31 - line 35 *;
 [X]  - BALE T L ET AL, "Characterization of CRF2 receptor deficient mice", SOCIETY FOR NEUROSCIENCE ABSTRACTS, & 28TH ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE, PART 1; LOS ANGELES, CALIFORNIA, USA; NOVEMBER 7-12, 1998, (1998), vol. 24, no. 1-2, ISSN 0190-5295, page 617, XP002300876 [X] 1,6 * the whole document *
 [PA]  - BALE T L ET AL, "Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress.", NATURE GENETICS. APR 2000, (200004), vol. 24, no. 4, ISSN 1061-4036, pages 410 - 414, XP002300877

DOI:   http://dx.doi.org/10.1038/74263
 [PA]  - KISHIMOTO T ET AL, "Deletion of crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2.", NATURE GENETICS. APR 2000, (200004), vol. 24, no. 4, ISSN 1061-4036, pages 415 - 419, XP002300878

DOI:   http://dx.doi.org/10.1038/74271
 [T]  - ANAGNOSTOPOULOS, ANNA V., "TBase:5768 Crhr2 (+/-)", T-BASE, JACKSON LABORATORY, (20000331), Database accession no. TBASE:5768, URL: HTTP://TBASE.JAX.ORG/, XP002300879 [T] * column A *
 [DA]  - LIEBSCH G ET AL, "Differential behavioural effects of chronic infusion of CRH 1 and CRH 2 receptor antisense oligonucleotides into the rat brain", JOURNAL OF PSYCHIATRIC RESEARCH, (199903), vol. 33, no. 2, ISSN 0022-3956, pages 153 - 163, XP008036948

DOI:   http://dx.doi.org/10.1016/S0022-3956(98)80047-2
International search[AP]  - COSTE ET AL., "Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin releasing hormone receptor-2", NATURE GENETICS, (200004), vol. 24, no. 4, doi:doi:10.1038/74255, pages 403 - 409, XP002932992

DOI:   http://dx.doi.org/10.1038/74255
 [AP]  - RADULOVIC ET AL., "Modulation of learning and anxiety by corticotropin-releasing factor (CRF) and stress", THE JOURNAL OF NEUROSCI., (19990615), vol. 19, no. 12, pages 5016 - 5025, XP002932989
 [A]  - LIAW ET AL., "Localization of agonist- and antagonist-binding domains of human corticotropin-releasing factor receptors", MOL. ENDOCRINOL., (199712), vol. 11, no. 13, pages 2048 - 2053, XP002932991

DOI:   http://dx.doi.org/10.1210/me.11.13.2048
 [A]  - RUHMANN ET AL., "Structural requirements for peptidic antagonists of the corticotropin-releasing factor receptor (CRFR)", PROC. NATL. ACAD. SCI. USA, (1996), vol. 95, no. 26, pages 15264 - 15269, XP002932990

DOI:   http://dx.doi.org/10.1073/pnas.95.26.15264
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