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EP1307219
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EP About this file: EP1307219
| EP1307219 - METHODS OF INHIBITING BINDING OF BETA-SHEET FIBRIL TO RAGE AND CONSEQUENCES THEREOF [Right-click to bookmark this link] | Status | The application has been refused Status updated on 13.11.2009 Database last updated on 03.09.2024 | Most recent event Tooltip | 13.11.2009 | Refusal of application | published on 16.12.2009 [2009/51] | Applicant(s) | For all designated states The Trustees of Columbia University in the City of New York Broadway and West 116th Street New York, NY 10027-6699 / US | [N/P] |
| Former [2003/19] | For all designated states The Trustees of Columbia University in the City of New York Broadway and West 116th Street New York, NY 10027-6699 / US | Inventor(s) | 01 /
STERN, David 63 Tanners Road Great Neck, NY 11026 / US | 02 /
YAN, Shi Du Apt. 4B, 60 Haven Avenue New York, NY 10032 / US | 03 /
SCHMIDT, Ann, Marie 242 Haven Road Franklin Lakes, NJ 07417 / US | [2003/19] | Representative(s) | Almond-Martin, Carol, et al Ernest Gutmann - Yves Plasseraud S.A.S. 3, rue Auber 75009 Paris / FR | [N/P] |
| Former [2003/19] | Almond-Martin, Carol, et al Ernest Gutmann - Yves Plasseraud S.A. 3, rue Chauveau-Lagarde 75008 Paris / FR | Application number, filing date | 00955464.3 | 11.08.2000 | [2003/19] | WO2000US22059 | Priority number, date | US19990374213 | 13.08.1999 Original published format: US 374213 | [2003/19] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO0112598 | Date: | 22.02.2001 | Language: | EN | [2001/08] | Type: | A2 Application without search report | No.: | EP1307219 | Date: | 07.05.2003 | Language: | EN | The application published by WIPO in one of the EPO official languages on 22.02.2001 takes the place of the publication of the European patent application. | [2003/19] | Search report(s) | International search report - published on: | US | 17.01.2002 | (Supplementary) European search report - dispatched on: | EP | 21.02.2005 | Classification | IPC: | A61K38/17, A61K39/395, C07K14/705, C07K16/28, C07K14/47, G01N33/68, A61P25/28 | [2005/13] | CPC: |
C07K16/2803 (EP,US);
A61P1/02 (EP);
A61P13/12 (EP);
A61P15/10 (EP);
A61P17/00 (EP);
A61P21/00 (EP);
A61P25/00 (EP);
A61P25/28 (EP);
A61P27/02 (EP);
A61P29/00 (EP);
A61P3/06 (EP);
A61P3/10 (EP);
A61P31/00 (EP);
A61P35/00 (EP);
A61P37/02 (EP);
A61P9/10 (EP);
A61P9/12 (EP);
A61K2039/505 (EP,US);
C07K2317/54 (EP,US)
(-)
|
| Former IPC [2003/19] | A61K39/00, A61K39/395, C07K5/00, C07K14/00, C07K16/00 | Designated contracting states | AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, MC, NL, PT, SE [2003/19] | Title | German: | VERFAHREN ZUR HEMMUNG DER BINDUNG VON BETA-FALTBLATTFIBRILLEN AN RAGE( ADVANCED GLYCATION ENDPRODUCT RECEPTOR ) | [2003/19] | English: | METHODS OF INHIBITING BINDING OF BETA-SHEET FIBRIL TO RAGE AND CONSEQUENCES THEREOF | [2003/19] | French: | PROCEDES D'INHIBITION DE LA LIAISON DE LA FIBRILLE A FEUILLETS BETA AU RECEPTEUR RAGE, ET LEURS CONSEQUENCES | [2003/19] | Entry into regional phase | 11.03.2002 | National basic fee paid | 11.03.2002 | Search fee paid | 11.03.2002 | Designation fee(s) paid | 11.03.2002 | Examination fee paid | Examination procedure | 13.03.2001 | Request for preliminary examination filed International Preliminary Examining Authority: US | 11.03.2002 | Examination requested [2003/19] | 02.05.2005 | Despatch of a communication from the examining division (Time limit: M06) | 14.11.2005 | Reply to a communication from the examining division | 29.11.2006 | Despatch of a communication from the examining division (Time limit: M06) | 11.06.2007 | Reply to a communication from the examining division | 29.06.2009 | Cancellation of oral proceeding that was planned for 30.06.2009 | 29.06.2009 | Minutes of oral proceedings despatched | 30.06.2009 | Date of oral proceedings | 30.06.2009 | Date of oral proceedings (cancelled) | 30.07.2009 | Despatch of communication that the application is refused, reason: substantive examination [2009/51] | 09.08.2009 | Application refused, date of legal effect [2009/51] | Fees paid | Renewal fee | 12.07.2002 | Renewal fee patent year 03 | 18.07.2003 | Renewal fee patent year 04 | 13.07.2004 | Renewal fee patent year 05 | 15.07.2005 | Renewal fee patent year 06 | 13.07.2006 | Renewal fee patent year 07 | 18.07.2007 | Renewal fee patent year 08 | 18.07.2008 | Renewal fee patent year 09 | 24.08.2009 | Renewal fee patent year 10 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A]WO9520979 (PICOWER INST MED RES [US], et al) [A] 3* page 15, line 28 - page 16, line 11; example 2 *; | [XY]WO9726913 (UNIV COLUMBIA [US]) [X] 1,2,4-33,35,39,41 * abstract * [Y] 34-40; | [XY]WO9918987 (UNIV COLUMBIA [US]) [X] 1,2,4-33,35,39,41 * abstract; page 47, lines 34-37; page 48, lines 21-31; claims 1-6,15-29,32,34,37-41 * [Y] 8-13,41; | [XY] - ZHU A ET AL, "Rage interaction with Abeta fibrils activates signal transduction mechanisms and results in apoptosis activation of MAP kinases and nuclear translocation of NF-EkB", SOCIETY FOR NEUROSCIENCE ABSTRACTS, & 28TH ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE, PART 1; LOS ANGELES, CALIFORNIA, USA; NOVEMBER 7-12, 1998, (1998), vol. 24, no. 1-2, ISSN 0190-5295, page 228, XP009043575 [X] 1,2,4-7,14-33,35,37-40 * abstract * [Y] 8-13,34-41 | [X] - YAN S D ET AL, "RAGE AND AMYLOID-BETA PEPTIDE NEUROTOXICITY IN ALZHEIMER'S DISEASE", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, (19960822), vol. 382, ISSN 0028-0836, pages 685 - 691, XP002916067 [X] 1,2,4-6,14-32,34-40 * page 685, paragraph joining left- and right-hand columns; page 687, right-hand column, last paragraph; page 688, left-hand column, lines 9-14; page 691, right-hand column, lines 2-8 * DOI: http://dx.doi.org/10.1038/382685a0 | [PX] - YAN S. D. ET AL, "Cellular cofactors potentiating induction of stress and cytotoxicity by amyloid beta-peptide", BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE, AMSTERDAM, NL, (20000726), vol. 1502, no. 1, ISSN 0925-4439, pages 145 - 157, XP004276982 [PX] 1,2,4-6,14-32,34-40 * the whole document * DOI: http://dx.doi.org/10.1016/S0925-4439(00)00041-7 | [PX] - YAN SHI DU ET AL, "Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis", NATURE MEDICINE, (200006), vol. 6, no. 6, ISSN 1078-8956, pages 643 - 651, XP002316616 [PX] 1-41 * the whole document * DOI: http://dx.doi.org/10.1038/76216 | [PX] - SOUSA MONICA MENDES ET AL, "Interaction of the receptor for advanced glycation end products (RAGE) with transthyretin triggers nuclear transcription factor kB (NF-kB) activation", LABORATORY INVESTIGATION, (200007), vol. 80, no. 7, ISSN 0023-6837, pages 1101 - 1110, XP002316617 [PX] 1,4,7-31,33-41 * abstract * | International search | [X]WO9739121 (SCHERING AG [DE]); | [X]WO9844955 (MINDSET LTD [IL], et al); | [X]US5864018 (MORSER MICHAEL JOHN [US], et al); | [XP]US6100098 (NEWKIRK MARIANNA M [CA]) |